HUE045556T2 - Eljárás egy kívánt fehérje elõállítására mikrobiális gazdaszervezetben - Google Patents

Eljárás egy kívánt fehérje elõállítására mikrobiális gazdaszervezetben

Info

Publication number
HUE045556T2
HUE045556T2 HUE14811909A HUE14811909A HUE045556T2 HU E045556 T2 HUE045556 T2 HU E045556T2 HU E14811909 A HUE14811909 A HU E14811909A HU E14811909 A HUE14811909 A HU E14811909A HU E045556 T2 HUE045556 T2 HU E045556T2
Authority
HU
Hungary
Prior art keywords
interest
protein
production
host organism
microbial host
Prior art date
Application number
HUE14811909A
Other languages
English (en)
Inventor
Stefan Jenewein
Max Fabian Felle
Jan Reyelt
Original Assignee
Basf Se
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Se filed Critical Basf Se
Publication of HUE045556T2 publication Critical patent/HUE045556T2/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/64General methods for preparing the vector, for introducing it into the cell or for selecting the vector-containing host
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245Escherichia (G)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67General methods for enhancing the expression
    • C12N15/68Stabilisation of the vector
HUE14811909A 2013-12-20 2014-12-12 Eljárás egy kívánt fehérje elõállítására mikrobiális gazdaszervezetben HUE045556T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP13198797 2013-12-20

Publications (1)

Publication Number Publication Date
HUE045556T2 true HUE045556T2 (hu) 2020-01-28

Family

ID=49885024

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE14811909A HUE045556T2 (hu) 2013-12-20 2014-12-12 Eljárás egy kívánt fehérje elõállítására mikrobiális gazdaszervezetben

Country Status (8)

Country Link
US (1) US20170022531A1 (hu)
EP (1) EP3083965B1 (hu)
JP (2) JP6692747B2 (hu)
CN (1) CN105849267A (hu)
CA (1) CA2933975C (hu)
DK (1) DK3083965T3 (hu)
HU (1) HUE045556T2 (hu)
WO (1) WO2015091280A1 (hu)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2021193932A (ja) 2020-06-12 2021-12-27 ナガセケムテックス株式会社 目的タンパク質の製造方法
MX2023001016A (es) 2020-07-24 2023-03-01 Basf Se Eliminacion simple de alanina racemasa y transcomplementacion.

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11196877A (ja) * 1998-01-12 1999-07-27 Akira Kaji リボソームリサイクリング因子(rrf)の阻害を検出する方法、同因子を阻害する物質のスクリーニング方法、該方法によってスクリーニングされた抗菌物質、並びにそれらの方法に有用なプラスミド及びそのプラスミドで形質転換された宿主細胞
SE0102204D0 (sv) * 2001-06-21 2001-06-21 Leif Isaksson New method
DE10360483B4 (de) * 2003-12-22 2007-11-15 Scil Proteins Gmbh Expressionsvektor und dessen Verwendung
JP2006067883A (ja) * 2004-09-01 2006-03-16 Kao Corp 組換えバチルス属細菌
JP4839169B2 (ja) * 2006-09-22 2011-12-21 花王株式会社 組換え微生物
DE102007021001A1 (de) * 2007-05-04 2008-11-06 Ab Enzymes Gmbh Expressionssystem zur antibiotikafreien Produktion von Polypeptiden
JP2009207417A (ja) * 2008-03-04 2009-09-17 Tottori Univ 線虫における簡便な多重遺伝子同時機能抑制法
CN103596970A (zh) * 2011-03-11 2014-02-19 帝斯曼知识产权资产管理有限公司 载体-宿主系统
IL237508B2 (en) * 2012-09-06 2023-04-01 Eveliqure Biotechnologies Gmbh A new live attenuated shigella vaccine

Also Published As

Publication number Publication date
EP3083965B1 (en) 2019-07-10
WO2015091280A1 (en) 2015-06-25
US20170022531A1 (en) 2017-01-26
JP6692747B2 (ja) 2020-05-13
EP3083965A1 (en) 2016-10-26
CA2933975A1 (en) 2015-06-25
DK3083965T3 (da) 2019-10-14
CN105849267A (zh) 2016-08-10
JP2020018304A (ja) 2020-02-06
JP2017500042A (ja) 2017-01-05
CA2933975C (en) 2022-06-21

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