HUE044837T2 - Eljárás hisztamin H3 receptor modulátorok elõállítására - Google Patents

Eljárás hisztamin H3 receptor modulátorok elõállítására

Info

Publication number
HUE044837T2
HUE044837T2 HUE17151754A HUE044837T2 HU E044837 T2 HUE044837 T2 HU E044837T2 HU E17151754 A HUE17151754 A HU E17151754A HU E044837 T2 HUE044837 T2 HU E044837T2
Authority
HU
Hungary
Prior art keywords
histamine
preparation
receptor modulators
modulators
receptor
Prior art date
Application number
Other languages
English (en)
Inventor
Diego Broggini
Vit Lellek
Neelakandha Mani
Susanne Lochner
Adrian Mauer
Daniel Pippel
Lana Young
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of HUE044837T2 publication Critical patent/HUE044837T2/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81Amides; Imides
    • C07D213/82Amides; Imides in position 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Plant Substances (AREA)
HUE17151754 2009-03-18 2010-03-17 Eljárás hisztamin H3 receptor modulátorok elõállítására HUE044837T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US16117709P 2009-03-18 2009-03-18

Publications (1)

Publication Number Publication Date
HUE044837T2 true HUE044837T2 (hu) 2019-11-28

Family

ID=42315639

Family Applications (2)

Application Number Title Priority Date Filing Date
HUE17151754 HUE044837T2 (hu) 2009-03-18 2010-03-17 Eljárás hisztamin H3 receptor modulátorok elõállítására
HUE10722449A HUE032345T2 (hu) 2009-03-18 2010-03-17 Eljárás hisztamin H3 receptor modulátorok elõállítására

Family Applications After (1)

Application Number Title Priority Date Filing Date
HUE10722449A HUE032345T2 (hu) 2009-03-18 2010-03-17 Eljárás hisztamin H3 receptor modulátorok elõállítására

Country Status (18)

Country Link
US (4) US8748596B2 (hu)
EP (3) EP3216784B1 (hu)
JP (1) JP5642149B2 (hu)
CN (1) CN102428070B (hu)
AU (1) AU2010226711B2 (hu)
CA (2) CA2755335C (hu)
CY (2) CY1119437T1 (hu)
DK (2) DK3216784T3 (hu)
ES (2) ES2625261T3 (hu)
HR (2) HRP20170776T1 (hu)
HU (2) HUE044837T2 (hu)
LT (2) LT2429996T (hu)
MX (3) MX347775B (hu)
PL (2) PL3216784T3 (hu)
PT (2) PT3216784T (hu)
SI (2) SI2429996T1 (hu)
TR (1) TR201902858T4 (hu)
WO (1) WO2010107897A2 (hu)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8748596B2 (en) 2009-03-18 2014-06-10 Janssen Pharmaceutica Nv Process for the preparation of histamine H3 receptor modulators
KR101427221B1 (ko) * 2012-08-29 2014-08-13 주식회사 에스텍파마 플루복사민 자유 염기의 정제방법 및 이를 이용한 고순도 플루복사민 말레이트의 제조방법
CN104447867B (zh) * 2013-09-17 2017-12-26 江苏天士力帝益药业有限公司 一种噻吩并哌啶衍生物、制备方法及其应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5724346B2 (hu) * 1973-06-22 1982-05-24
NZ576432A (en) * 2002-10-23 2010-06-25 Janssen Pharmaceutica Nv Piperazinyl and diazapanyl benzamides and benzthioamides
AU2007256931B2 (en) 2006-05-30 2013-01-24 Janssen Pharmaceutica N.V. Substituted pyridyl amide compounds as modulators of the histamine H3 receptor
KR101546712B1 (ko) * 2007-11-20 2015-08-24 얀센 파마슈티카 엔.브이. 히스타민 h3 수용체의 조절제로서 사이클로알킬옥시- 및 헤테로사이클로알킬옥시피리딘 화합물
US8748596B2 (en) 2009-03-18 2014-06-10 Janssen Pharmaceutica Nv Process for the preparation of histamine H3 receptor modulators

Also Published As

Publication number Publication date
MX2011009784A (es) 2011-09-30
US20140343279A1 (en) 2014-11-20
SI2429996T1 (sl) 2017-08-31
EP3492451A2 (en) 2019-06-05
AU2010226711B2 (en) 2015-06-18
MX349489B (es) 2017-07-31
CA2755335A1 (en) 2010-09-23
EP3492451B1 (en) 2021-11-03
CA2965059C (en) 2020-04-28
PL3216784T3 (pl) 2019-07-31
JP2012520889A (ja) 2012-09-10
PL2429996T3 (pl) 2017-08-31
EP3216784A1 (en) 2017-09-13
EP3492451A3 (en) 2019-07-31
US10323002B2 (en) 2019-06-18
DK2429996T3 (en) 2017-06-19
EP2429996A2 (en) 2012-03-21
CY1119437T1 (el) 2018-03-07
SI3216784T1 (sl) 2019-05-31
TR201902858T4 (tr) 2019-03-21
HUE032345T2 (hu) 2017-09-28
DK3216784T3 (en) 2019-04-08
US20170057919A1 (en) 2017-03-02
WO2010107897A2 (en) 2010-09-23
US20180022704A1 (en) 2018-01-25
CN102428070B (zh) 2015-05-06
CY1121556T1 (el) 2020-05-29
LT3216784T (lt) 2019-03-25
JP5642149B2 (ja) 2014-12-17
US20120029189A1 (en) 2012-02-02
PT2429996T (pt) 2017-06-12
EP2429996B1 (en) 2017-03-08
US9809547B2 (en) 2017-11-07
CA2755335C (en) 2018-09-18
HRP20170776T1 (hr) 2017-08-11
MX347775B (es) 2017-05-11
CN102428070A (zh) 2012-04-25
ES2714852T3 (es) 2019-05-30
LT2429996T (lt) 2017-06-12
HRP20190476T1 (hr) 2019-05-03
CA2965059A1 (en) 2010-09-23
PT3216784T (pt) 2019-04-01
ES2625261T3 (es) 2017-07-19
WO2010107897A3 (en) 2011-04-14
US9518021B2 (en) 2016-12-13
US8748596B2 (en) 2014-06-10
EP3216784B1 (en) 2018-12-26
AU2010226711A1 (en) 2011-10-13

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