LT3216784T - Histamino h3 receptoriaus moduliatorių gamybos būdas - Google Patents

Histamino h3 receptoriaus moduliatorių gamybos būdas

Info

Publication number
LT3216784T
LT3216784T LTEP17151754.3T LT17151754T LT3216784T LT 3216784 T LT3216784 T LT 3216784T LT 17151754 T LT17151754 T LT 17151754T LT 3216784 T LT3216784 T LT 3216784T
Authority
LT
Lithuania
Prior art keywords
histamine
preparation
receptor modulators
modulators
receptor
Prior art date
Application number
LTEP17151754.3T
Other languages
English (en)
Inventor
Diego Broggini
Vit Lellek
Neelakandha Mani
Susanne Lochner
Adrian Mauer
Daniel Pippel
Lana Young
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of LT3216784T publication Critical patent/LT3216784T/lt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81Amides; Imides
    • C07D213/82Amides; Imides in position 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Plant Substances (AREA)
LTEP17151754.3T 2009-03-18 2010-03-17 Histamino h3 receptoriaus moduliatorių gamybos būdas LT3216784T (lt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US16117709P 2009-03-18 2009-03-18

Publications (1)

Publication Number Publication Date
LT3216784T true LT3216784T (lt) 2019-03-25

Family

ID=42315639

Family Applications (2)

Application Number Title Priority Date Filing Date
LTEP17151754.3T LT3216784T (lt) 2009-03-18 2010-03-17 Histamino h3 receptoriaus moduliatorių gamybos būdas
LTEP10722449.5T LT2429996T (lt) 2009-03-18 2010-03-17 Histamino h3 receptoriaus moduliatorių gamybos būdas

Family Applications After (1)

Application Number Title Priority Date Filing Date
LTEP10722449.5T LT2429996T (lt) 2009-03-18 2010-03-17 Histamino h3 receptoriaus moduliatorių gamybos būdas

Country Status (18)

Country Link
US (4) US8748596B2 (lt)
EP (3) EP3216784B1 (lt)
JP (1) JP5642149B2 (lt)
CN (1) CN102428070B (lt)
AU (1) AU2010226711B2 (lt)
CA (2) CA2965059C (lt)
CY (2) CY1119437T1 (lt)
DK (2) DK2429996T3 (lt)
ES (2) ES2714852T3 (lt)
HR (2) HRP20170776T1 (lt)
HU (2) HUE044837T2 (lt)
LT (2) LT3216784T (lt)
MX (3) MX2011009784A (lt)
PL (2) PL2429996T3 (lt)
PT (2) PT2429996T (lt)
SI (2) SI2429996T1 (lt)
TR (1) TR201902858T4 (lt)
WO (1) WO2010107897A2 (lt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2714852T3 (es) 2009-03-18 2019-05-30 Janssen Pharmaceutica Nv Procedimiento para la preparación de moduladores de receptores H3 de histamina
KR101427221B1 (ko) * 2012-08-29 2014-08-13 주식회사 에스텍파마 플루복사민 자유 염기의 정제방법 및 이를 이용한 고순도 플루복사민 말레이트의 제조방법
CN104447867B (zh) * 2013-09-17 2017-12-26 江苏天士力帝益药业有限公司 一种噻吩并哌啶衍生物、制备方法及其应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5724346B2 (lt) * 1973-06-22 1982-05-24
ES2335584T3 (es) * 2002-10-23 2010-03-30 Janssen Pharmaceutica Nv Piperazinil y diazepanil - benzamidas y benzotioamidas.
CA2653940C (en) * 2006-05-30 2015-07-14 Janssen Pharmaceutica N.V. Substituted pyridyl amide compounds as modulators of the histamine h3 receptor
CN105712977B (zh) 2007-11-20 2021-06-29 詹森药业有限公司 作为组胺h3受体调节剂的环烷基氧基吡啶化合物和杂环烷基氧基吡啶化合物
ES2714852T3 (es) 2009-03-18 2019-05-30 Janssen Pharmaceutica Nv Procedimiento para la preparación de moduladores de receptores H3 de histamina

Also Published As

Publication number Publication date
HRP20190476T1 (hr) 2019-05-03
DK3216784T3 (en) 2019-04-08
LT2429996T (lt) 2017-06-12
CA2965059C (en) 2020-04-28
US8748596B2 (en) 2014-06-10
PT3216784T (pt) 2019-04-01
ES2714852T3 (es) 2019-05-30
HUE044837T2 (hu) 2019-11-28
PT2429996T (pt) 2017-06-12
HUE032345T2 (en) 2017-09-28
CA2755335A1 (en) 2010-09-23
US20140343279A1 (en) 2014-11-20
CA2965059A1 (en) 2010-09-23
PL3216784T3 (pl) 2019-07-31
CY1119437T1 (el) 2018-03-07
JP2012520889A (ja) 2012-09-10
EP3492451B1 (en) 2021-11-03
JP5642149B2 (ja) 2014-12-17
EP3492451A3 (en) 2019-07-31
US20180022704A1 (en) 2018-01-25
MX2011009784A (es) 2011-09-30
CA2755335C (en) 2018-09-18
EP3216784A1 (en) 2017-09-13
ES2625261T3 (es) 2017-07-19
CN102428070B (zh) 2015-05-06
MX347775B (es) 2017-05-11
US20120029189A1 (en) 2012-02-02
US20170057919A1 (en) 2017-03-02
PL2429996T3 (pl) 2017-08-31
AU2010226711B2 (en) 2015-06-18
TR201902858T4 (tr) 2019-03-21
MX349489B (es) 2017-07-31
US9518021B2 (en) 2016-12-13
US10323002B2 (en) 2019-06-18
EP2429996B1 (en) 2017-03-08
WO2010107897A2 (en) 2010-09-23
CN102428070A (zh) 2012-04-25
EP3492451A2 (en) 2019-06-05
CY1121556T1 (el) 2020-05-29
EP2429996A2 (en) 2012-03-21
EP3216784B1 (en) 2018-12-26
WO2010107897A3 (en) 2011-04-14
SI3216784T1 (sl) 2019-05-31
HRP20170776T1 (hr) 2017-08-11
DK2429996T3 (en) 2017-06-19
US9809547B2 (en) 2017-11-07
SI2429996T1 (sl) 2017-08-31
AU2010226711A1 (en) 2011-10-13

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