HUE043136T2 - Eljárás lakózamid elõállítására - Google Patents
Eljárás lakózamid elõállításáraInfo
- Publication number
- HUE043136T2 HUE043136T2 HUE15003058A HUE15003058A HUE043136T2 HU E043136 T2 HUE043136 T2 HU E043136T2 HU E15003058 A HUE15003058 A HU E15003058A HU E15003058 A HUE15003058 A HU E15003058A HU E043136 T2 HUE043136 T2 HU E043136T2
- Authority
- HU
- Hungary
- Prior art keywords
- lacosamide
- preparation
- Prior art date
Links
- VPPJLAIAVCUEMN-GFCCVEGCSA-N lacosamide Chemical compound COC[C@@H](NC(C)=O)C(=O)NCC1=CC=CC=C1 VPPJLAIAVCUEMN-GFCCVEGCSA-N 0.000 title 1
- 229960002623 lacosamide Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/14—Preparation of carboxylic acid amides by formation of carboxamide groups together with reactions not involving the carboxamide groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN5001CH2015 IN2015CH05001A (enExample) | 2015-09-18 | 2015-09-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUE043136T2 true HUE043136T2 (hu) | 2019-07-29 |
Family
ID=54398495
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE15003058A HUE043136T2 (hu) | 2015-09-18 | 2015-10-23 | Eljárás lakózamid elõállítására |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US9447024B1 (enExample) |
| EP (1) | EP3144295B1 (enExample) |
| KR (1) | KR101886643B1 (enExample) |
| CN (1) | CN106543018A (enExample) |
| DK (1) | DK3144295T3 (enExample) |
| ES (1) | ES2708176T3 (enExample) |
| HR (1) | HRP20190403T1 (enExample) |
| HU (1) | HUE043136T2 (enExample) |
| IN (1) | IN2015CH05001A (enExample) |
| SI (1) | SI3144295T1 (enExample) |
| TR (1) | TR201901398T4 (enExample) |
| TW (1) | TWI634100B (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107641087A (zh) * | 2017-06-01 | 2018-01-30 | 合肥远志医药科技开发有限公司 | 一种工业化拉科酰胺的制备方法 |
| CN108558690B (zh) * | 2018-03-28 | 2021-04-20 | 浙江海正药业股份有限公司 | 环丝氨酸酯化物盐酸盐的晶型及其制备方法 |
| CN110320291A (zh) * | 2019-06-21 | 2019-10-11 | 山东省药学科学院 | 一种hplc法定量检测拉考沙胺注射液含量的方法 |
| CN115825300B (zh) * | 2022-11-30 | 2024-12-06 | 山东百诺医药股份有限公司 | 一种检测拉考沙胺对映异构体的反相液相色谱方法 |
| CN118271200A (zh) * | 2024-03-29 | 2024-07-02 | 北京澳合药物研究院有限公司 | 一种拉考沙胺的工业化制备方法和其应用 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5773475A (en) | 1997-03-17 | 1998-06-30 | Research Corporation Technologies, Inc. | Anticonvulsant enantiomeric amino acid derivatives |
| EP1642889A1 (en) | 2004-10-02 | 2006-04-05 | Schwarz Pharma Ag | Improved synthesis scheme for lacosamide |
| US8093426B2 (en) | 2007-12-04 | 2012-01-10 | Ranbaxy Laboratories Limited | Intermediate compounds and their use in preparation of lacosamide |
| JP5564570B2 (ja) | 2009-09-25 | 2014-07-30 | カディラ・ヘルスケア・リミテッド | ラコサミドおよびその中間体の調製方法 |
| IT1398044B1 (it) | 2010-01-29 | 2013-02-07 | Archimica Srl | Processo per la preparazione della lacosamide |
| WO2011095995A1 (en) * | 2010-02-08 | 2011-08-11 | Natco Pharma Limited | A process for the preparation of lacosamide |
| US8907132B2 (en) * | 2010-02-09 | 2014-12-09 | Msn Laboratories Private Limited | Process for preparing (R)-2-acetamido-N-benzyl-3-methoxy-propionamide |
| US20130123537A1 (en) * | 2010-05-17 | 2013-05-16 | K a s s Narayan Garimella | Process for the preparation of lacosamide |
| EP2399901A1 (en) * | 2010-06-23 | 2011-12-28 | Archimica GmbH | Intermediate for producing lacosamide and a process for its preparation and conversion to lacosamide |
| ES2619403T3 (es) * | 2010-10-19 | 2017-06-26 | Euticals Gmbh | Proceso para producir lacosamida |
| EP2487152A1 (en) | 2010-11-17 | 2012-08-15 | UCB Pharma GmbH | Process for the preparation of Lacosamide including resolution of O-methyl-DL-serine |
| CN103113256A (zh) * | 2011-11-17 | 2013-05-22 | 苏州洪瑞医药科技有限公司 | 一种拉科酰胺的合成方法 |
| CN104892450A (zh) * | 2015-06-01 | 2015-09-09 | 江苏海岸药业有限公司 | 一种拉科酰胺的制备方法 |
-
2015
- 2015-09-18 IN IN5001CH2015 patent/IN2015CH05001A/en unknown
- 2015-10-16 US US14/885,321 patent/US9447024B1/en active Active
- 2015-10-23 DK DK15003058.3T patent/DK3144295T3/en active
- 2015-10-23 SI SI201530610T patent/SI3144295T1/sl unknown
- 2015-10-23 ES ES15003058T patent/ES2708176T3/es active Active
- 2015-10-23 HU HUE15003058A patent/HUE043136T2/hu unknown
- 2015-10-23 TR TR2019/01398T patent/TR201901398T4/tr unknown
- 2015-10-23 EP EP15003058.3A patent/EP3144295B1/en active Active
- 2015-11-10 KR KR1020150157145A patent/KR101886643B1/ko active Active
- 2015-12-25 TW TW104143667A patent/TWI634100B/zh active
- 2015-12-29 CN CN201511017774.6A patent/CN106543018A/zh active Pending
-
2019
- 2019-03-01 HR HRP20190403TT patent/HRP20190403T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US9447024B1 (en) | 2016-09-20 |
| CN106543018A (zh) | 2017-03-29 |
| EP3144295A1 (en) | 2017-03-22 |
| SI3144295T1 (sl) | 2019-03-29 |
| KR101886643B1 (ko) | 2018-08-08 |
| DK3144295T3 (en) | 2019-03-25 |
| KR20170034281A (ko) | 2017-03-28 |
| EP3144295B1 (en) | 2018-12-05 |
| ES2708176T3 (es) | 2019-04-09 |
| TWI634100B (zh) | 2018-09-01 |
| TR201901398T4 (tr) | 2019-02-21 |
| IN2015CH05001A (enExample) | 2015-10-16 |
| HRP20190403T1 (hr) | 2019-05-03 |
| TW201711992A (zh) | 2017-04-01 |
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