HUE040647T2 - A központi idegrendszerrel kapcsolatos betegségek vagy állapotok kezelésére hasznos N-(hetero)aril-szubsztituált heterociklusos származékok - Google Patents
A központi idegrendszerrel kapcsolatos betegségek vagy állapotok kezelésére hasznos N-(hetero)aril-szubsztituált heterociklusos származékokInfo
- Publication number
- HUE040647T2 HUE040647T2 HUE15774987A HUE15774987A HUE040647T2 HU E040647 T2 HUE040647 T2 HU E040647T2 HU E15774987 A HUE15774987 A HU E15774987A HU E15774987 A HUE15774987 A HU E15774987A HU E040647 T2 HUE040647 T2 HU E040647T2
- Authority
- HU
- Hungary
- Prior art keywords
- heteroyclic
- hetero
- aryl
- diseases
- substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/48—Oxygen atoms attached in position 4 having an acyclic carbon atom attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Diabetes (AREA)
- Pain & Pain Management (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Child & Adolescent Psychology (AREA)
- Addiction (AREA)
- Anesthesiology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1416351.3A GB201416351D0 (en) | 2014-09-16 | 2014-09-16 | Heterocyclic derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUE040647T2 true HUE040647T2 (hu) | 2019-03-28 |
Family
ID=51869694
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE15774987A HUE040647T2 (hu) | 2014-09-16 | 2015-09-14 | A központi idegrendszerrel kapcsolatos betegségek vagy állapotok kezelésére hasznos N-(hetero)aril-szubsztituált heterociklusos származékok |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US9920053B2 (hu) |
| EP (1) | EP3194385B3 (hu) |
| JP (3) | JP6800855B2 (hu) |
| CN (2) | CN111848577B (hu) |
| AU (1) | AU2015316472C1 (hu) |
| BR (1) | BR112017005241B1 (hu) |
| CA (1) | CA2997869C (hu) |
| CY (1) | CY1120875T1 (hu) |
| DK (1) | DK3194385T6 (hu) |
| ES (1) | ES2687604T7 (hu) |
| GB (1) | GB201416351D0 (hu) |
| HR (1) | HRP20181391T1 (hu) |
| HU (1) | HUE040647T2 (hu) |
| LT (1) | LT3194385T (hu) |
| PL (1) | PL3194385T6 (hu) |
| PT (1) | PT3194385T (hu) |
| RS (1) | RS57617B1 (hu) |
| SI (1) | SI3194385T1 (hu) |
| WO (1) | WO2016042453A1 (hu) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201416351D0 (en) * | 2014-09-16 | 2014-10-29 | Shire Internat Gmbh | Heterocyclic derivatives |
| WO2020113094A1 (en) | 2018-11-30 | 2020-06-04 | Nuvation Bio Inc. | Pyrrole and pyrazole compounds and methods of use thereof |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2734265B1 (fr) | 1995-05-17 | 1997-06-13 | Adir | Nouveaux composes spiro heterocycliques, leur procede de preparation et les compositions pharmaceutiques les contenant |
| US6326368B1 (en) * | 1996-03-27 | 2001-12-04 | Dupont Pharmaceuticals Company | Aryloxy- and arylthiosubstituted pyrimidines and triazines and derivatives thereof |
| US6835371B1 (en) | 1997-09-12 | 2004-12-28 | David R. Elmaleh | Diagnostic and therapeutic piperazine and piperidine compounds and process |
| EA200200731A1 (ru) * | 1999-12-30 | 2002-12-26 | Х. Лундбекк А/С | Производные фенилпиперазинила |
| PL366630A1 (en) * | 2000-08-30 | 2005-02-07 | F.Hoffmann-La Roche Ag | Selective cyclic peptides |
| AU2003225305A1 (en) * | 2002-05-08 | 2003-11-11 | Bristol-Myers Squibb Company | Pyridine-based thyroid receptor ligands |
| MXPA05000370A (es) | 2002-07-05 | 2005-04-19 | Targacept Inc | Compuestos n-aril diazaespiraciclicos y metodos de preparacion y usos de los mismos. |
| US20070275990A1 (en) | 2003-11-13 | 2007-11-29 | Ono Pharmaceutical Co., Ltd. | Heterocyclic Spiro Compound |
| JP2008510711A (ja) | 2004-08-20 | 2008-04-10 | ターガセプト，インコーポレイテッド | 嗜癖治療におけるｎ−アリールジアザスピラ環状化合物の使用 |
| WO2006066747A1 (en) * | 2004-12-20 | 2006-06-29 | F. Hoffmann-La Roche Ag | 4-aminopiperidine derivatives |
| CN101228127B (zh) * | 2005-05-30 | 2012-05-16 | Msdk.K.公司 | 哌啶衍生物 |
| JP5140597B2 (ja) | 2005-10-21 | 2013-02-06 | メルク・シャープ・エンド・ドーム・コーポレイション | カリウムチャネル阻害剤 |
| GB0522715D0 (en) * | 2005-11-08 | 2005-12-14 | Helperby Therapeutics Ltd | New use |
| EP1968961A2 (en) * | 2005-12-21 | 2008-09-17 | Decode Genetics EHF | Biaryl nitrogen heterocycle inhibitors of lta4h for treating inflammation |
| US7728031B2 (en) * | 2006-02-24 | 2010-06-01 | Abbott Laboratories | Octahydro-pyrrolo[3,4-b]pyrrole derivatives |
| WO2007148185A2 (en) * | 2006-06-21 | 2007-12-27 | Pfizer Products Inc. | Substituted 3 -amino- pyrrolidino-4 -lactams as dpp inhibitors |
| CA2656089A1 (en) * | 2006-06-29 | 2008-01-03 | Janssen Pharmaceutica N.V. | Substituted benzyl amine compounds |
| CL2008000467A1 (es) * | 2007-02-14 | 2008-08-22 | Janssen Pharmaceutica Nv | Compuestos derivados de 2-aminopirimidina, moduladores del receptor histamina h4; su procedimiento de preparacion; composicion farmaceutica que comprende a dichos compuestos; y su uso para tratar un trastorno inflamatorio seleccionado de alegia, asma |
| US8148408B2 (en) * | 2008-05-09 | 2012-04-03 | Abbott Laboratories | Selective substituted pyridine ligands for neuronal nicotinic receptors |
| EP2606049A4 (en) | 2010-08-17 | 2014-01-08 | Albany Molecular Res Inc | 2,5-METHANO- AND 2,5-ETHANO-TETRAHYDROBENZAZEPINE DERIVATIVES AND USES THEREOF FOR BLOCKING NOREPINEPHRINE, DOPAMINE, AND SEROTONIN REUPTAKE |
| WO2015031036A1 (en) | 2013-08-26 | 2015-03-05 | Purdue Pharma L.P. | Azaspiro[4.5] decane derivatives and use thereof |
| US9815813B2 (en) * | 2014-01-17 | 2017-11-14 | Novartis Ag | 1-(triazin-3-yl/pyridazin-3-yl)-piper(-azine)idine derivatives and compositions therefor for inhibiting the activity of SHP2 |
| JP6574438B2 (ja) | 2014-03-17 | 2019-09-11 | リマインド エヌヴイＲｅｍｙｎｄ Ｎｖ | ２，７−ジアザスピロ［３．５］ノナン化合物 |
| GB201416351D0 (en) * | 2014-09-16 | 2014-10-29 | Shire Internat Gmbh | Heterocyclic derivatives |
-
2014
- 2014-09-16 GB GBGB1416351.3A patent/GB201416351D0/en not_active Ceased
-
2015
- 2015-09-14 AU AU2015316472A patent/AU2015316472C1/en active Active
- 2015-09-14 WO PCT/IB2015/057031 patent/WO2016042453A1/en active Application Filing
- 2015-09-14 DK DK15774987.0T patent/DK3194385T6/da active
- 2015-09-14 CN CN202010667511.4A patent/CN111848577B/zh active Active
- 2015-09-14 SI SI201530344T patent/SI3194385T1/sl unknown
- 2015-09-14 PL PL15774987T patent/PL3194385T6/pl unknown
- 2015-09-14 CN CN201580057347.2A patent/CN107001318B/zh active Active
- 2015-09-14 CA CA2997869A patent/CA2997869C/en active Active
- 2015-09-14 RS RS20180999A patent/RS57617B1/sr unknown
- 2015-09-14 BR BR112017005241-5A patent/BR112017005241B1/pt active IP Right Grant
- 2015-09-14 HU HUE15774987A patent/HUE040647T2/hu unknown
- 2015-09-14 EP EP15774987.0A patent/EP3194385B3/en active Active
- 2015-09-14 LT LTEP15774987.0T patent/LT3194385T/lt unknown
- 2015-09-14 JP JP2017534018A patent/JP6800855B2/ja active Active
- 2015-09-14 PT PT15774987T patent/PT3194385T/pt unknown
- 2015-09-14 ES ES15774987T patent/ES2687604T7/es active Active
- 2015-09-14 US US15/511,515 patent/US9920053B2/en active Active
-
2018
- 2018-08-23 CY CY181100879T patent/CY1120875T1/el unknown
- 2018-08-29 HR HRP20181391TT patent/HRP20181391T1/hr unknown
-
2020
- 2020-11-25 JP JP2020195362A patent/JP2021042231A/ja active Pending
-
2022
- 2022-10-28 JP JP2022173152A patent/JP2023012506A/ja active Pending
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL253945A0 (en) | kdm1a inhibitors to treat the disease | |
| HK1256795A1 (zh) | 可用於治療自身免疫疾病的二吡唑基衍生物 | |
| HK1217706A1 (zh) | 用於治療過度增殖性病症的 -乙酰基氨基- 苯基-雜芳基-氨基羰基或苯基-雜芳基-羰基氨基 苯衍生物 | |
| RS63231B1 (sr) | Primena derivata hinolina u lečenju upalnih bolesti | |
| IL249502A0 (en) | Novel therapeutic uses of benzylideneguanidine derivatives for the treatment of protein-associated diseases | |
| HK1232220A1 (zh) | 用於治療心血管疾病的 -苄基異喹啉衍生物 | |
| PL3210973T3 (pl) | Związki heteroarylowe do leczenia chorób oczu | |
| IL259297A (en) | Heterocyclic compounds for the treatment of disease | |
| HRP20181391T1 (hr) | N-(hetero)aril-supstituirani heterociklički derivati korisni za liječenje bolesti ili stanja povezanih sa središnjim živčanim sustavom | |
| EP3122356A4 (en) | Treatment of parkinson's disease through arfgap1 inhibition using substituted piperazine derivatives | |
| AP2015008751A0 (en) | 3-acetylamino-1-(phenyl-heteroaryl-aminocarbonyl or phenyl-heteroaryl-carbonylamino)benzene derivatives for the treatment of hyperproliferative disorders |