HUE027749T2 - Methods of treating hepatocellular carcinoma - Google Patents

Methods of treating hepatocellular carcinoma Download PDF

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Publication number
HUE027749T2
HUE027749T2 HUE11760333A HUE11760333A HUE027749T2 HU E027749 T2 HUE027749 T2 HU E027749T2 HU E11760333 A HUE11760333 A HU E11760333A HU E11760333 A HUE11760333 A HU E11760333A HU E027749 T2 HUE027749 T2 HU E027749T2
Authority
HU
Hungary
Prior art keywords
composition
nanoparticles
albumin
taxane
agent
Prior art date
Application number
HUE11760333A
Other languages
English (en)
Hungarian (hu)
Inventor
Winnie Yeo
Nathalie Wong
Original Assignee
Abraxis Bioscience Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abraxis Bioscience Llc filed Critical Abraxis Bioscience Llc
Publication of HUE027749T2 publication Critical patent/HUE027749T2/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/513Organic macromolecular compounds; Dendrimers
    • A61K9/5169Proteins, e.g. albumin, gelatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • A61K31/713Double-stranded nucleic acids or oligonucleotides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Nanotechnology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
HUE11760333A 2010-03-26 2011-03-25 Methods of treating hepatocellular carcinoma HUE027749T2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US31815310P 2010-03-26 2010-03-26

Publications (1)

Publication Number Publication Date
HUE027749T2 true HUE027749T2 (en) 2016-10-28

Family

ID=44673662

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE11760333A HUE027749T2 (en) 2010-03-26 2011-03-25 Methods of treating hepatocellular carcinoma

Country Status (20)

Country Link
US (3) US9370494B2 (Direct)
EP (2) EP2898884B1 (Direct)
JP (2) JP5847156B2 (Direct)
KR (1) KR101786142B1 (Direct)
CN (2) CN103052385B (Direct)
AU (1) AU2011230512B2 (Direct)
BR (1) BR112012024349A2 (Direct)
CA (2) CA2793536C (Direct)
DK (1) DK2552438T3 (Direct)
ES (2) ES2580135T3 (Direct)
HR (1) HRP20160609T1 (Direct)
HU (1) HUE027749T2 (Direct)
IL (2) IL221886A (Direct)
LT (1) LT2552438T (Direct)
MX (2) MX346861B (Direct)
NZ (1) NZ602382A (Direct)
PL (1) PL2552438T3 (Direct)
PT (1) PT2552438T (Direct)
TW (1) TWI495467B (Direct)
WO (1) WO2011119988A1 (Direct)

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Also Published As

Publication number Publication date
JP2013523656A (ja) 2013-06-17
JP2015134825A (ja) 2015-07-27
PT2552438T (pt) 2016-07-07
MX359413B (es) 2018-09-27
AU2011230512B2 (en) 2016-09-15
ES2580135T3 (es) 2016-08-19
US20140079787A1 (en) 2014-03-20
US20130115296A1 (en) 2013-05-09
US9370494B2 (en) 2016-06-21
CN103052385A (zh) 2013-04-17
DK2552438T3 (en) 2016-07-04
LT2552438T (lt) 2016-09-26
TWI495467B (zh) 2015-08-11
EP2552438A4 (en) 2013-09-04
MX2012010936A (es) 2012-10-10
EP2898884B1 (en) 2018-05-09
KR20130062922A (ko) 2013-06-13
EP2552438A1 (en) 2013-02-06
CN103052385B (zh) 2015-05-27
PL2552438T3 (pl) 2016-12-30
CA3051495A1 (en) 2011-09-29
NZ602382A (en) 2014-11-28
HK1181665A1 (zh) 2013-11-15
CA2793536C (en) 2019-10-01
CA2793536A1 (en) 2011-09-29
TW201138765A (en) 2011-11-16
BR112012024349A2 (pt) 2016-05-24
IL221886A (en) 2016-08-31
US20160374952A1 (en) 2016-12-29
IL247171B (en) 2019-02-28
HK1212926A1 (en) 2016-06-24
ES2675212T3 (es) 2018-07-09
JP5847156B2 (ja) 2016-01-20
EP2552438B1 (en) 2016-05-11
WO2011119988A1 (en) 2011-09-29
HRP20160609T1 (hr) 2016-09-23
EP2898884A1 (en) 2015-07-29
MX346861B (es) 2017-04-04
AU2011230512A1 (en) 2012-10-04
CN104784121A (zh) 2015-07-22
KR101786142B1 (ko) 2017-10-17

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