HU9401936D0 - Process and uses for 4,5-diohydrogeldanamycin and its hydroquinone - Google Patents

Process and uses for 4,5-diohydrogeldanamycin and its hydroquinone

Info

Publication number
HU9401936D0
HU9401936D0 HU9401936A HU9401936A HU9401936D0 HU 9401936 D0 HU9401936 D0 HU 9401936D0 HU 9401936 A HU9401936 A HU 9401936A HU 9401936 A HU9401936 A HU 9401936A HU 9401936 D0 HU9401936 D0 HU 9401936D0
Authority
HU
Hungary
Prior art keywords
diohydrogeldanamycin
hydroquinone
Prior art date
Application number
HU9401936A
Other languages
English (en)
Hungarian (hu)
Inventor
Mark T Jefferson
Walter P Cullen
Mikel P Moyer
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of HU9401936D0 publication Critical patent/HU9401936D0/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10—Nitrogen as only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D225/00—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom
    • C07D225/04—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D225/06—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with one six-membered ring

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
HU9401936A 1992-01-06 1992-12-03 Process and uses for 4,5-diohydrogeldanamycin and its hydroquinone HU9401936D0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US81723592A 1992-01-06 1992-01-06

Publications (1)

Publication Number Publication Date
HU9401936D0 true HU9401936D0 (en) 1994-09-28

Family

ID=25222638

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9401936A HU9401936D0 (en) 1992-01-06 1992-12-03 Process and uses for 4,5-diohydrogeldanamycin and its hydroquinone

Country Status (15)

Country Link
JP (1) JPH06510913A (fi)
KR (1) KR940703923A (fi)
CN (1) CN1074937A (fi)
AU (1) AU3225693A (fi)
BR (1) BR9207024A (fi)
CA (1) CA2127457A1 (fi)
CZ (1) CZ390592A3 (fi)
FI (1) FI943207A (fi)
HU (1) HU9401936D0 (fi)
IL (1) IL104289A0 (fi)
MX (1) MX9300011A (fi)
NO (1) NO942532D0 (fi)
PT (1) PT101169A (fi)
WO (1) WO1993014215A1 (fi)
ZA (1) ZA9333B (fi)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2794342B2 (ja) * 1993-06-29 1998-09-03 ファイザー・インク． 抗癌遺伝子剤および抗癌剤としてのアンサマイシン誘導体
US5932566A (en) * 1994-06-16 1999-08-03 Pfizer Inc. Ansamycin derivatives as antioncogene and anticancer agents
US6852496B1 (en) 1997-08-12 2005-02-08 Oregon Health And Science University Methods of screening for agents that promote nerve cell growth
US6872715B2 (en) * 2001-08-06 2005-03-29 Kosan Biosciences, Inc. Benzoquinone ansamycins
ATE387198T1 (de) 2001-09-24 2008-03-15 Conforma Therapeutic Corp Verfahren zur herstellung von 17-allyl-amino- geldanamycin (17-aag) und anderer ansamycine
EP1923061A1 (en) 2001-09-24 2008-05-21 Conforma Therapeutic Corporation Process for preparing 17-Allyl amino geldanamycin (17-AAG) and other ansamycins
WO2003066005A2 (en) 2002-02-08 2003-08-14 Conforma Therapeutics Corporation Ansamycins having improved pharmacological and biological properties
TW200303363A (en) * 2002-02-25 2003-09-01 Upjohn Co Process to prepare and isolate geldanamycin
US7241754B2 (en) 2003-06-13 2007-07-10 Kosan Biosciences, Inc. 2-Desmethyl ansamycin compounds
US6887993B1 (en) 2003-11-12 2005-05-03 Kosan Biosciences, Inc. 11-O-methylgeldanamycin compounds
US6855705B1 (en) 2003-11-12 2005-02-15 Kosan Biosciences, Inc. 11-O-methylgeldanamycin compounds
US6875863B1 (en) 2003-11-12 2005-04-05 Kosan Biosciences, Inc. 11-O-methylgeldanamycin compounds
CA2545457A1 (en) 2003-11-12 2005-06-23 Kosan Biosciences, Inc. 11-o-methylgeldanamycin compounds
JP2007512369A (ja) * 2003-11-26 2007-05-17 エンテロス・インコーポレーテッド 低酸素誘導因子１αアンタゴニストを用いる慢性関節リウマチの処置
CN1898212B (zh) * 2003-12-23 2012-06-13 无限发现公司 用于治疗癌症的包含苯醌的安沙霉素类似物
KR101154351B1 (ko) 2003-12-23 2012-06-15 인피니티 디스커버리, 인코포레이티드 암 치료를 위한 벤조퀴논-함유 안사마이신의 유사체
US20060019941A1 (en) * 2003-12-23 2006-01-26 Infinity Pharmaceuticals, Inc. Analogs of benzoquinone-containing ansamycins and methods of use thereof
CA2602257A1 (en) 2005-03-30 2006-10-05 Conforma Therapeutics Corporation Alkynyl pyrrolopyrimidines and related analogs as hsp90-inhibitors
AU2007319014B2 (en) * 2006-11-09 2013-03-28 Bristol-Myers Squibb Company Novel compounds and methods for their production
PE20081506A1 (es) 2006-12-12 2008-12-09 Infinity Discovery Inc Formulaciones de ansamicina
CN100500668C (zh) * 2006-12-19 2009-06-17 中国人民解放军军事医学科学院毒物药物研究所 格尔德霉素衍生物及其制备方法和制备药物的用途
JP2010516282A (ja) 2007-01-26 2010-05-20 コーサン バイオサイエンシーズ， インコーポレイテッド 工学的生合成によるマクロラクタム
WO2009130706A1 (en) * 2008-04-21 2009-10-29 Biocon Limited A process for isolation and purification of geldanamycin
WO2010045442A1 (en) 2008-10-15 2010-04-22 Infinity Discovery, Inc. Ansamycin hydroquinone compositions
CN102030764B (zh) * 2010-11-12 2012-07-04 中国医学科学院医药生物技术研究所 4，5双氢噻嗪酮格尔德霉素及其制备方法
CN103305563B (zh) * 2013-06-14 2014-12-03 湖南农业大学 一种以链霉菌提制阿里沙霉素的方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3595955A (en) * 1969-03-26 1971-07-27 Upjohn Co Geldanamycin and process for producing same

Also Published As

Publication number Publication date
WO1993014215A1 (en) 1993-07-22
NO942532L (no) 1994-07-05
FI943207A0 (fi) 1994-07-05
IL104289A0 (en) 1993-05-13
BR9207024A (pt) 1995-12-05
KR940703923A (ko) 1994-12-12
CZ390592A3 (en) 1993-08-11
CN1074937A (zh) 1993-08-04
NO942532D0 (no) 1994-07-05
CA2127457A1 (en) 1993-07-22
FI943207A (fi) 1994-07-05
ZA9333B (en) 1994-07-05
PT101169A (pt) 1994-03-31
JPH06510913A (ja) 1994-12-08
AU3225693A (en) 1993-08-03
MX9300011A (es) 1993-12-01

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