HU9400061D0 - Pyrrolidine and thiazolidine derivatives, preparation thereof and drugs containing same - Google Patents
Pyrrolidine and thiazolidine derivatives, preparation thereof and drugs containing sameInfo
- Publication number
- HU9400061D0 HU9400061D0 HU9400061A HU9400061A HU9400061D0 HU 9400061 D0 HU9400061 D0 HU 9400061D0 HU 9400061 A HU9400061 A HU 9400061A HU 9400061 A HU9400061 A HU 9400061A HU 9400061 D0 HU9400061 D0 HU 9400061D0
- Authority
- HU
- Hungary
- Prior art keywords
- preparation
- pyrrolidine
- containing same
- drugs containing
- thiazolidine derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/06—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with radicals, containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Biophysics (AREA)
- Neurosurgery (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Rheumatology (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9108675A FR2678938B1 (fr) | 1991-07-10 | 1991-07-10 | Derives de pyrrolidine, leur preparation et les medicaments les contenant. |
PCT/FR1992/000626 WO1993001167A1 (fr) | 1991-07-10 | 1992-07-03 | Derives de pyrrolidine et thiazolidine, leur preparation et les medicaments les contenant |
Publications (3)
Publication Number | Publication Date |
---|---|
HU9400061D0 true HU9400061D0 (en) | 1994-05-30 |
HUT70403A HUT70403A (en) | 1995-10-30 |
HU223470B1 HU223470B1 (hu) | 2004-07-28 |
Family
ID=9414933
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU9400061A HU223470B1 (hu) | 1991-07-10 | 1992-07-03 | Pirrolidin- és tiazolidinszármazékok, előállításuk és ezeket tartalmazó gyógyszerkészítmények |
Country Status (23)
Country | Link |
---|---|
US (1) | US5610144A (hu) |
EP (2) | EP0527069A1 (hu) |
JP (1) | JP3034043B2 (hu) |
KR (1) | KR100234927B1 (hu) |
AT (1) | ATE120732T1 (hu) |
AU (1) | AU662345B2 (hu) |
BR (1) | BR1100717A (hu) |
CA (1) | CA2102697C (hu) |
CZ (1) | CZ283602B6 (hu) |
DE (1) | DE69201956T2 (hu) |
DK (1) | DK0593639T3 (hu) |
ES (1) | ES2071510T3 (hu) |
FI (1) | FI105190B (hu) |
FR (1) | FR2678938B1 (hu) |
HU (1) | HU223470B1 (hu) |
IE (1) | IE66331B1 (hu) |
NO (1) | NO180166C (hu) |
NZ (1) | NZ243514A (hu) |
PL (5) | PL171333B1 (hu) |
RU (1) | RU2118316C1 (hu) |
SK (1) | SK1694A3 (hu) |
WO (1) | WO1993001167A1 (hu) |
ZA (1) | ZA925128B (hu) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2695641B1 (fr) * | 1992-09-11 | 1994-11-25 | Rhone Poulenc Rorer Sa | (Amino-3 phényl)-1 éthanesulfonate d'hydroquinine optiquement actif, sa préparation et son utilisation. |
FR2700166B1 (fr) * | 1993-01-07 | 1995-02-17 | Rhone Poulenc Rorer Sa | Dérivés de pyrrolidine, leur préparation et les médicaments les contenant. |
FR2700168B1 (fr) * | 1993-01-07 | 1995-02-03 | Rhone Poulenc Rorer Sa | Dérivés de thiazolidine, leur préparation et les médicaments les contenant. |
FR2700165B1 (fr) * | 1993-01-07 | 1995-02-17 | Rhone Poulenc Rorer Sa | Dérivés de pyrrolidine, leur préparation et les médicaments les contenant. |
FR2700167B1 (fr) * | 1993-01-07 | 1995-02-03 | Rhone Poulenc Rorer Sa | Dérivés de pyrrolidine et thiazolidine, leur préparation et les médicaments les contenant. |
US5744485A (en) * | 1994-03-25 | 1998-04-28 | Vertex Pharmaceuticals Incorporated | Carbamates and ureas as modifiers of multi-drug resistance |
FR2721314B1 (fr) * | 1994-06-20 | 1996-07-19 | Rhone Poulenc Rorer Sa | Dérivés de pyrrolidine, leur préparation et les médicaments les contenant. |
FR2721608B1 (fr) * | 1994-06-22 | 1996-07-19 | Rhone Poulenc Rorer Sa | Dérivés de thiazolidine, leur préparation et les médicaments les contenant. |
FR2734724B1 (fr) * | 1995-06-01 | 1997-07-04 | Rhone Poulenc Rorer Sa | Application de derives de pyrrolidine a la preparation de medicaments destines au traitement de l'alcoolisme |
US6297269B1 (en) | 1995-06-06 | 2001-10-02 | Pfizer Inc. | Substituted n-(indole-2-carbonyl-) amides and derivatives as glycogen phosphorylase inhibitors |
KR100241643B1 (ko) * | 1995-06-06 | 2000-03-02 | 디. 제이. 우드 | 당뇨병치료제인 치환된 N-(인돌-2-카르보닐)-β-알라님아미드 및 그의 유도체 |
FR2744361B1 (fr) * | 1996-02-07 | 1998-02-27 | Rhone Poulenc Rorer Sa | Application de derives de pyrrolidine a la preparation de medicaments destines au traitement de l'abus de drogues ou de substances donnant lieu a des pharmacomanies ou a un usage excessif |
TW442449B (en) | 1996-07-04 | 2001-06-23 | Hoechst Ag | Process for preparing 1,2-dichloroethane by direct chlorination |
DE19816880A1 (de) * | 1998-04-17 | 1999-10-21 | Boehringer Ingelheim Pharma | Neue Diphenyl-substituierte 5-Ring-Heterocyclen, Verfahren zu ihrer Herstellung sowie deren Verwendung als Arzneimittel |
US6638950B2 (en) * | 2000-06-21 | 2003-10-28 | Bristol-Myers Squibb Pharma Company | Piperidine amides as modulators of chemokine receptor activity |
US6277877B1 (en) * | 2000-08-15 | 2001-08-21 | Pfizer, Inc. | Substituted n-(indole-2-carbonyl)glycinamides and derivates as glycogen phosphorylase inhibitors |
US7125891B2 (en) * | 2000-10-30 | 2006-10-24 | Janssen Pharmaceutica N.V. | Tripeptidyl peptidase inhibitors |
US7105556B2 (en) | 2001-05-30 | 2006-09-12 | Bristol-Myers Squibb Company | Conformationally constrained analogs useful as antidiabetic and antiobesity agents and method |
US7262207B2 (en) | 2002-09-19 | 2007-08-28 | Abbott Laboratories | Pharmaceutical compositions as inhibitors of dipeptidyl peptidase-IV (DPP-IV) |
EP1560811B9 (en) * | 2002-09-19 | 2008-03-05 | Abbott Laboratories | Pharmaceutical compositions as inhibitors of dipeptidyl peptidase-iv (dpp-iv) |
US7238724B2 (en) | 2002-09-19 | 2007-07-03 | Abbott Laboratories | Pharmaceutical compositions as inhibitors of dipeptidyl peptidase-IV (DPP-IV) |
US6846836B2 (en) * | 2003-04-18 | 2005-01-25 | Bristol-Myers Squibb Company | N-substituted phenylurea inhibitors of mitochondrial F1F0 ATP hydrolase |
US7230002B2 (en) | 2004-02-03 | 2007-06-12 | Glenmark Pharmaceuticals Ltd. | Dipeptidyl peptidase IV inhibitors; processes for their preparation and compositions thereof |
JP2007522247A (ja) * | 2004-02-11 | 2007-08-09 | ザ オハイオ ステート ユニバーシティー リサーチ ファウンデーション | 細胞増殖の阻害を示すアナログ、それを作製する方法およびその使用 |
WO2007086584A1 (ja) * | 2006-01-30 | 2007-08-02 | Meiji Seika Kaisha, Ltd. | 新規FabKおよびFabI/K阻害剤 |
CA2657930A1 (en) * | 2006-07-20 | 2008-01-24 | Abbott Laboratories | Synthesis of (2s,5r)-5-ethynyl-1-{n-(4-methyl-1-(4-carboxy-pyridin-2-yl)piperidin-4-yl)glycyl}pyrrolidine-2-carbonitrile |
US8247438B2 (en) | 2008-02-27 | 2012-08-21 | Neuropill, Inc. | Methods for treating schizophrenia |
CN101407502B (zh) * | 2008-11-21 | 2010-12-22 | 南京大学 | 一类n-(叔丁氧基羰基)噻唑烷酸类化合物及其制法和用途 |
DE102009004204A1 (de) * | 2009-01-09 | 2010-07-15 | Christian-Albrechts-Universität Zu Kiel | Verfahren zur verbesserten Bioaktivierung von Arzneistoffen |
WO2011073376A1 (en) * | 2009-12-18 | 2011-06-23 | Euroscreen S.A. | Pyrrolidine or thiazolidine carboxylic acid derivatives, pharmaceutical composition and methods for use in treating metabolic disordersas as agonists of g- protein coupled receptor 43 (gpr43) |
WO2012036962A2 (en) | 2010-09-13 | 2012-03-22 | Amylin Pharmaceuticals, Inc. | C-terminal amidation of polypeptides |
BR112016011917B1 (pt) | 2013-11-27 | 2022-10-11 | Epics Therapeutics | Compostos, composição e métodos farmacêuticos para o uso no tratamento de doenças inflamatórias |
CA2972731A1 (en) | 2015-01-24 | 2016-07-28 | Chi-Huey Wong | Cancer markers and methods of use thereof |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH362072A (de) * | 1957-03-19 | 1962-05-31 | Ciba Geigy | Verfahren zur Herstellung neuer Acylpiperidine |
US4499102A (en) * | 1979-12-13 | 1985-02-12 | Santen Pharmaceutical Co., Ltd. | Thiazolidine and pyrrolidine compounds and pharmaceutical compositions containing them |
DE3272505D1 (en) * | 1981-03-09 | 1986-09-18 | Merck & Co Inc | Substituted thiazolidine carboxylic acid analogs and derivatives as antihypertensives |
DE3332633A1 (de) * | 1983-09-09 | 1985-04-04 | Luitpold-Werk Chemisch-pharmazeutische Fabrik GmbH & Co, 8000 München | Substituierte carbonsaeurederivate, verfahren zu ihrer herstellung, und arzneimittel |
AU629376B2 (en) * | 1989-08-04 | 1992-10-01 | Mitsubishi Chemical Corporation | 1-phenylalkyl-3-phenylurea derivatives |
US5258405A (en) * | 1990-03-12 | 1993-11-02 | Yamanouchi Pharmaceutical Co., Ltd. | Urea derivatives and salts thereof in method for inhibiting the ACAT enzyme |
-
1991
- 1991-07-10 FR FR9108675A patent/FR2678938B1/fr not_active Expired - Fee Related
-
1992
- 1992-07-03 EP EP92401904A patent/EP0527069A1/fr active Pending
- 1992-07-03 PL PL92302029A patent/PL171333B1/pl unknown
- 1992-07-03 AU AU23275/92A patent/AU662345B2/en not_active Expired
- 1992-07-03 CZ CZ9449A patent/CZ283602B6/cs not_active IP Right Cessation
- 1992-07-03 DK DK92915456.5T patent/DK0593639T3/da active
- 1992-07-03 HU HU9400061A patent/HU223470B1/hu active IP Right Grant
- 1992-07-03 US US08/175,381 patent/US5610144A/en not_active Expired - Lifetime
- 1992-07-03 WO PCT/FR1992/000626 patent/WO1993001167A1/fr active IP Right Grant
- 1992-07-03 KR KR1019940700052A patent/KR100234927B1/ko not_active IP Right Cessation
- 1992-07-03 EP EP92915456A patent/EP0593639B1/fr not_active Expired - Lifetime
- 1992-07-03 DE DE69201956T patent/DE69201956T2/de not_active Expired - Lifetime
- 1992-07-03 PL PL92313381A patent/PL171112B1/pl unknown
- 1992-07-03 JP JP5502018A patent/JP3034043B2/ja not_active Expired - Lifetime
- 1992-07-03 PL PL92313382A patent/PL171095B1/pl unknown
- 1992-07-03 AT AT92915456T patent/ATE120732T1/de active
- 1992-07-03 CA CA002102697A patent/CA2102697C/fr not_active Expired - Lifetime
- 1992-07-03 ES ES92915456T patent/ES2071510T3/es not_active Expired - Lifetime
- 1992-07-03 PL PL92313380A patent/PL171054B1/pl unknown
- 1992-07-03 PL PL92313379A patent/PL171094B1/pl unknown
- 1992-07-03 SK SK16-94A patent/SK1694A3/sk unknown
- 1992-07-09 ZA ZA925128A patent/ZA925128B/xx unknown
- 1992-07-09 IE IE922244A patent/IE66331B1/en not_active IP Right Cessation
- 1992-07-10 NZ NZ243514A patent/NZ243514A/en not_active IP Right Cessation
-
1993
- 1993-01-21 RU RU94015258/04A patent/RU2118316C1/ru active
- 1993-11-26 NO NO934300A patent/NO180166C/no not_active IP Right Cessation
-
1994
- 1994-01-07 FI FI940072A patent/FI105190B/fi not_active IP Right Cessation
-
1997
- 1997-05-04 BR BR1100717-6A patent/BR1100717A/pt active IP Right Grant
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
HFG4 | Patent granted, date of granting |
Effective date: 20040513 |
|
HC9A | Change of name, address |
Owner name: AVENTIS PHARMA S.A., FR Free format text: FORMER OWNER(S): RHONE-POULENC RORER S.A., FR |
|
FH91 | Appointment of a representative |
Free format text: FORMER REPRESENTATIVE(S): DR. LANG TIVADARNE, S.B.G. & K. BUDAPEST NEMZETKOEZI SZABADALMI IRODA, HU Representative=s name: DANUBIA SZABADALMI ES JOGI IRODA KFT., HU |
|
FH92 | Termination of representative |
Representative=s name: DR. LANG TIVADARNE, S.B.G. & K. BUDAPEST NEMZE, HU |