HU220611B1 - Nukleozidok foszfolipidszármazékai, ezeket hatóanyagként tartalmazó gyógyszerkészítmények és az előállításukra szolgáló eljárások - Google Patents

Nukleozidok foszfolipidszármazékai, ezeket hatóanyagként tartalmazó gyógyszerkészítmények és az előállításukra szolgáló eljárások Download PDF

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Publication number
HU220611B1
HU220611B1 HU9300468A HU46893A HU220611B1 HU 220611 B1 HU220611 B1 HU 220611B1 HU 9300468 A HU9300468 A HU 9300468A HU 46893 A HU46893 A HU 46893A HU 220611 B1 HU220611 B1 HU 220611B1
Authority
HU
Hungary
Prior art keywords
formula
phosphoric acid
decyloxy
propyl ester
group
Prior art date
Application number
HU9300468A
Other languages
English (en)
Hungarian (hu)
Other versions
HU9300468D0 (en
HUT62910A (en
Inventor
Dieter Herrmann
Herbert Leinert
Alfred Mertens
Harald Zilch
Original Assignee
Roche Diagnostics Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE4026265A external-priority patent/DE4026265A1/de
Application filed by Roche Diagnostics Gmbh filed Critical Roche Diagnostics Gmbh
Publication of HU9300468D0 publication Critical patent/HU9300468D0/hu
Publication of HUT62910A publication Critical patent/HUT62910A/hu
Publication of HU220611B1 publication Critical patent/HU220611B1/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
HU9300468A 1990-08-20 1991-08-14 Nukleozidok foszfolipidszármazékai, ezeket hatóanyagként tartalmazó gyógyszerkészítmények és az előállításukra szolgáló eljárások HU220611B1 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4026265A DE4026265A1 (de) 1990-08-20 1990-08-20 Neue phospholipid-derivate von nucleosiden, deren herstellung sowie deren verwendung als antivirale arzneimittel

Publications (3)

Publication Number Publication Date
HU9300468D0 HU9300468D0 (en) 1993-05-28
HUT62910A HUT62910A (en) 1993-06-28
HU220611B1 true HU220611B1 (hu) 2002-03-28

Family

ID=6412536

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9300468A HU220611B1 (hu) 1990-08-20 1991-08-14 Nukleozidok foszfolipidszármazékai, ezeket hatóanyagként tartalmazó gyógyszerkészítmények és az előállításukra szolgáló eljárások

Country Status (10)

Country Link
JP (1) JP3032576B2 (zh)
KR (1) KR970011307B1 (zh)
CZ (1) CZ287942B6 (zh)
HU (1) HU220611B1 (zh)
MX (1) MX9100676A (zh)
NZ (1) NZ239422A (zh)
RO (1) RO115163B1 (zh)
RU (1) RU2104282C1 (zh)
TW (1) TW207544B (zh)
ZA (1) ZA916542B (zh)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7026469B2 (en) * 2000-10-19 2006-04-11 Wake Forest University School Of Medicine Compositions and methods of double-targeting virus infections and cancer cells
RU2293739C2 (ru) * 2002-07-26 2007-02-20 Закрытое акционерное общество "Производственно-коммерческая Ассоциация АЗТ" 5`-холинфосфат 3`-азидо-3`-дезокситимидина как антивирусный агент

Also Published As

Publication number Publication date
KR970011307B1 (ko) 1997-07-09
TW207544B (zh) 1993-06-11
CZ287942B6 (cs) 2001-03-14
NZ239422A (en) 1993-09-27
HU9300468D0 (en) 1993-05-28
MX9100676A (es) 1992-04-01
ZA916542B (en) 1992-05-27
CZ18093A3 (en) 1993-06-16
HUT62910A (en) 1993-06-28
RO115163B1 (ro) 1999-11-30
JP3032576B2 (ja) 2000-04-17
JPH06500543A (ja) 1994-01-20
RU2104282C1 (ru) 1998-02-10
KR930701470A (ko) 1993-06-11

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