HU210667B - Eljárás N,N'-bisz(dikarboxi-metil)-1,4,10,13-tetraoxa-7,16-diaza-ciklooktadekán-származékok sói és komplexei és a vegyületeket tartalmazó gyógyászati készítmények előállítására - Google Patents

Eljárás N,N'-bisz(dikarboxi-metil)-1,4,10,13-tetraoxa-7,16-diaza-ciklooktadekán-származékok sói és komplexei és a vegyületeket tartalmazó gyógyászati készítmények előállítására

Info

Publication number
HU210667B
HU210667B HU90145A HU14590A HU210667B HU 210667 B HU210667 B HU 210667B HU 90145 A HU90145 A HU 90145A HU 14590 A HU14590 A HU 14590A HU 210667 B HU210667 B HU 210667B
Authority
HU
Hungary
Prior art keywords
tetraoxa
diaza
bis
derivatives
hydrogen
Prior art date
Application number
HU90145A
Other languages
English (en)
Hungarian (hu)
Other versions
HU900145D0 (en
Inventor
László Varga
József Emri
Béla Győri
Zoltán Kovács
B. László Sztanyik
Ernő Brücher
Béla Kanyár
Ödön Király
Original Assignee
NUCLETECH Kutató-Fejlesztő, Egészségügyi és Kereskedelmi Korlátolt Felelősségű Társaság
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by NUCLETECH Kutató-Fejlesztő, Egészségügyi és Kereskedelmi Korlátolt Felelősségű Társaság filed Critical NUCLETECH Kutató-Fejlesztő, Egészségügyi és Kereskedelmi Korlátolt Felelősségű Társaság
Priority to HU9502769A priority Critical patent/HUT73493A/hu
Priority to HU90145A priority patent/HU210667B/hu
Publication of HU900145D0 publication Critical patent/HU900145D0/hu
Priority to PCT/HU1990/000070 priority patent/WO1991010655A1/en
Priority to AU67116/90A priority patent/AU645507B2/en
Priority to JP2515439A priority patent/JPH04505626A/ja
Priority to SU905001786A priority patent/RU2060256C1/ru
Priority to CA002048627A priority patent/CA2048627A1/en
Priority to KR1019910701044A priority patent/KR970009042B1/ko
Priority to UA5001786A priority patent/UA35547C2/uk
Priority to EP90916523A priority patent/EP0463123A1/en
Priority to IN943/MAS/90A priority patent/IN171733B/en
Priority to US08/102,955 priority patent/US5440031A/en
Priority to HU95P/P00244P priority patent/HU211923A9/hu
Publication of HU210667B publication Critical patent/HU210667B/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D273/00—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
    • C07D273/08—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00 having two nitrogen atoms and more than one oxygen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D273/00—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
HU90145A 1990-01-16 1990-01-16 Eljárás N,N'-bisz(dikarboxi-metil)-1,4,10,13-tetraoxa-7,16-diaza-ciklooktadekán-származékok sói és komplexei és a vegyületeket tartalmazó gyógyászati készítmények előállítására HU210667B (hu)

Priority Applications (13)

Application Number Priority Date Filing Date Title
HU9502769A HUT73493A (en) 1990-01-16 1990-01-16 Salts and complexes of n,n`-bis(dicarboxy-methyl)-1,4,10,13-tetraoxa-7,16-diaza-cyclooctadekane derivatives, ad pharmaceutical compositions containing them
HU90145A HU210667B (hu) 1990-01-16 1990-01-16 Eljárás N,N'-bisz(dikarboxi-metil)-1,4,10,13-tetraoxa-7,16-diaza-ciklooktadekán-származékok sói és komplexei és a vegyületeket tartalmazó gyógyászati készítmények előállítására
EP90916523A EP0463123A1 (en) 1990-01-16 1990-11-07 1,4,10,13-tetraoxa-7,16-diazacyclooctadecane derivatives, pharmaceutical compositions containing them and their use for the removal of toxic metal ions and radioactive isotopes from the living organism
CA002048627A CA2048627A1 (en) 1990-01-16 1990-11-07 1,4,10,13-tetraoxa-7,16-diazacyclooctadecane derivatives, pharmaceutical compositions containing them and their use for the removal of toxic metal ions and radioactive isotopes from the living organism
AU67116/90A AU645507B2 (en) 1990-01-16 1990-11-07 1,4,10,13-tetraoxa-7,16-diazacyclooctadecane derivatives, pharmaceutical compositions containing them and their use for the removal of toxic metal ions and radioactive isotopes from the living organism
JP2515439A JPH04505626A (ja) 1990-01-16 1990-11-07 １，４，１０，１３，―テトラオキサ―７，１６―ジアザシクロオクタデカン誘導体類、それらを含む医薬組成物及び生物からの毒性金属イオン及び放射性同位体の除去のためへのそれらの使用
SU905001786A RU2060256C1 (ru) 1990-01-16 1990-11-07 Производные 1,4,10,13-тетраокса-7,16-диазациклооктадекана, обладающие свойством выводить радиоактивные изотопы из живого организма, и фармацевтическая композиция для выведения из организма радиоактивных изотопов
PCT/HU1990/000070 WO1991010655A1 (en) 1990-01-16 1990-11-07 1,4,10,13-tetraoxa-7,16-diazacyclooctadecane derivatives, pharmaceutical compositions containing them and their use for the removal of toxic metal ions and radioactive isotopes from the living organism
KR1019910701044A KR970009042B1 (ko) 1990-01-16 1990-11-07 1,4,10,13-테트라옥사-7,16-디아자씨클로옥타데칸 유도체와 상기 유도체를 함유한 약제학적 조성물
UA5001786A UA35547C2 (uk) 1990-01-16 1990-11-07 ПОХІДНІ 1,4,10,13-ТЕТРАОКСА-7,16-ДІАЗАЦИКЛООКТАДЕКАНУ, ДИНАТРІЄВА СІЛЬ N,N<sup>1 </sup>-БІС(ДИКАРБОКСИМЕТИЛ)-1,4,10,13-ТЕТРАОКСА-7,16-ДІАЗАЦИКЛООКТА-ДЕКАН-КАЛЬЦІЄВОГО КОМПЛЕКСУ ТА КОМПОЗИЦІЇ НА ЇХ ОСНОВІ ДЛЯ ВИВЕДЕННЯ З ЖИВОГО ОРГАНІЗМУ ІОНІВ МЕТАЛІВ, ЩО ЙОГО УРАЖАЮТЬ, ОСОБЛИВО РАДІОАКТИВНИХ
IN943/MAS/90A IN171733B (cs) 1990-01-16 1990-11-22
US08/102,955 US5440031A (en) 1990-01-16 1993-08-06 1,4,10,13-tetraoxa-7,16-diazacyclooctadecane derivatives, pharmaceutical compositions containing them and their use for the removal of toxic metal ions and radioactive isotopes from living organism
HU95P/P00244P HU211923A9 (hu) 1990-01-16 1995-06-19 1,4,10,13-Tetraoxa-7,16-diaza-ciklooktadekán-származékok, a vegyületeket tartalmazó gyógyászati készítmények és alkalmazásuk toxikus fémionok és radioaktív izotópok élő szervezetből történő eltávolítására Az átmeneti oltalom az 1-7. igénypontokra vonatkozik.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU90145A HU210667B (hu) 1990-01-16 1990-01-16 Eljárás N,N'-bisz(dikarboxi-metil)-1,4,10,13-tetraoxa-7,16-diaza-ciklooktadekán-származékok sói és komplexei és a vegyületeket tartalmazó gyógyászati készítmények előállítására

Publications (2)

Publication Number Publication Date
HU900145D0 HU900145D0 (en) 1990-03-28
HU210667B true HU210667B (hu) 1998-03-30

Family

ID=10948158

Family Applications (2)

Application Number Title Priority Date Filing Date
HU90145A HU210667B (hu) 1990-01-16 1990-01-16 Eljárás N,N'-bisz(dikarboxi-metil)-1,4,10,13-tetraoxa-7,16-diaza-ciklooktadekán-származékok sói és komplexei és a vegyületeket tartalmazó gyógyászati készítmények előállítására
HU9502769A HUT73493A (en) 1990-01-16 1990-01-16 Salts and complexes of n,n`-bis(dicarboxy-methyl)-1,4,10,13-tetraoxa-7,16-diaza-cyclooctadekane derivatives, ad pharmaceutical compositions containing them

Family Applications After (1)

Application Number Title Priority Date Filing Date
HU9502769A HUT73493A (en) 1990-01-16 1990-01-16 Salts and complexes of n,n`-bis(dicarboxy-methyl)-1,4,10,13-tetraoxa-7,16-diaza-cyclooctadekane derivatives, ad pharmaceutical compositions containing them

Country Status (10)

Country Link
EP (1) EP0463123A1 (cs)
JP (1) JPH04505626A (cs)
KR (1) KR970009042B1 (cs)
AU (1) AU645507B2 (cs)
CA (1) CA2048627A1 (cs)
HU (2) HU210667B (cs)
IN (1) IN171733B (cs)
RU (1) RU2060256C1 (cs)
UA (1) UA35547C2 (cs)
WO (1) WO1991010655A1 (cs)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06505795A (ja) * 1990-09-27 1994-06-30 リサーチ・コーポレイション・テクノロジーズ キレート化剤
IL117302A (en) * 1995-03-07 2005-03-20 Univ Hawaii Cryptophycin derivatives, methods for the production thereof and pharmaceutical compositions containing the same
HUP1100731A2 (en) 2011-12-30 2013-06-28 Stratoxer S Kft Complex forming compounds
EA201201241A1 (ru) * 2012-06-19 2013-12-30 Елена Владимировна ОРЛОВА БИОБЕЗОПАСНЫЙ НАНОКОМПОЗИТНЫЙ ПОЛИМЕРНЫЙ СОРБЕНТ ДЛЯ СЕЛЕКТИВНОГО СВЯЗЫВАНИЯ ИЗОТОПОВ Sr И Cs ИЗ ЖИДКИХ СРЕД И СЫРЬЕВАЯ СМЕСЬ ДЛЯ ЕГО ИЗГОТОВЛЕНИЯ

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4190462A (en) * 1978-07-04 1980-02-26 Shell Oil Company Dissolving barium sulfate scale with aqueous solutions of salts of carboxymethyl monocyclic macrocyclic polyamines
US4597903A (en) * 1984-08-21 1986-07-01 University Of Maryland Process for the direct preparation of N,N-disubstituted derivatives for 4,13-diaza-18-crown-6
JPS61263964A (ja) * 1985-05-17 1986-11-21 Terumo Corp 新規クラウン（チオ）エ−テルおよびその製造方法

Also Published As

Publication number Publication date
UA35547C2 (uk) 2001-04-16
RU2060256C1 (ru) 1996-05-20
CA2048627A1 (en) 1991-07-17
HUT73493A (en) 1996-08-28
WO1991010655A1 (en) 1991-07-25
KR920701184A (ko) 1992-08-11
EP0463123A1 (en) 1992-01-02
HU9502769D0 (en) 1995-11-28
JPH04505626A (ja) 1992-10-01
HU900145D0 (en) 1990-03-28
KR970009042B1 (ko) 1997-06-03
AU645507B2 (en) 1994-01-20
AU6711690A (en) 1991-08-05
IN171733B (cs) 1992-12-26

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Legal Events

Date Code Title Description
HMM4 Cancellation of final prot. due to non-payment of fee
HPC4 Succession in title of patentee

Owner name: NUCLETECH KUTATO-FEJLESZTOE, EGESZSEGUEGYI ES KERE

HMM4 Cancellation of final prot. due to non-payment of fee
HMM4 Cancellation of final prot. due to non-payment of fee