HU191694B - Process for production of new derivatives of amineburnan carbonic acid - Google Patents
Process for production of new derivatives of amineburnan carbonic acid Download PDFInfo
- Publication number
- HU191694B HU191694B HU842703A HU270384A HU191694B HU 191694 B HU191694 B HU 191694B HU 842703 A HU842703 A HU 842703A HU 270384 A HU270384 A HU 270384A HU 191694 B HU191694 B HU 191694B
- Authority
- HU
- Hungary
- Prior art keywords
- amino
- formula
- hydrogen
- acid
- group
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/06—Peri-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Cephalosporin Compounds (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Fats And Perfumes (AREA)
Abstract
Die Erfindung betrifft ein Verfahren zur Herstellung von neuen, in der 9- oder 11-Stellung eine gegebenenfalls substituierte Aminogruppe enthaltenden Eburnancarbonsaeure-Derivaten, von ihren optischen aktiven Isomeren und ihren Salze. Die neuen Verbindungen entsprechen der allgemeinen Formel (I), worin R fuer eine Aminogruppe oder eine Gruppe der allgemeinen Formel -NH-COR1 steht, worin R1 z. B. Wasserstoff, eine cycloaliphatische Kohlenwasserstoffgruppe mit 3.8 Kohlenstoffatomen oder eine aromatische Kohlenwasserstoffgruppe mit 6-14 Kohlenstoffatomen oder eine Gruppe -NH-SO2R2 steht, worin R2 z. B. eine gegebenenfalls substituierte aliphatische Kohlenwasserstoffgruppe mit 1-10 Kohlenstoffatomen ist, R3 z. B. fuer Wasserstoff oder eine gegebenenfalls substituierte Kohlenwasserstoffgruppe mit 1-10 Kohlenstoffatomen steht. A eine Hydroxylgruppe und B Wasserstoff bedeutet oder A und B gemeinsam eine chemische Bindung bilden. Die Verbindungen der allgemeinen Formel (I) weisen wertvolle pharmakologische Wirkungen auf. Die Herstellung der Verbindungen erfolgt gemaess Analogieverfahren in an sich bekannter Weise. Weitere Bedeutungen der Substituenten sind dem Anspruch 1 zu entnehmen. Formel I
Priority Applications (21)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU842703A HU191694B (en) | 1984-07-11 | 1984-07-11 | Process for production of new derivatives of amineburnan carbonic acid |
AU44770/85A AU577393B2 (en) | 1984-07-11 | 1985-07-10 | Apovincamine or vincamine derivatives |
PL25449685A PL254496A1 (en) | 1984-07-11 | 1985-07-11 | A method of aminoeburano-carboxyl acid production |
FI852750A FI852750L (fi) | 1984-07-11 | 1985-07-11 | Foerfarande foer framstaellning aminoeburnankarboxylsyraderivat. |
YU01153/85A YU115385A (en) | 1984-07-11 | 1985-07-11 | Process for obtaining derivatives of aminoeburnancarbonic acid |
DD85278517A DD235646A5 (de) | 1984-07-11 | 1985-07-11 | Verfahren zur herstellung von neuen aminoeburnancarbonsaeure-derivaten |
PT80799A PT80799B (en) | 1984-07-11 | 1985-07-11 | Aminoeburnanecarboxylic acid derivatives pharmaceutical compositions containing them and process for preparing same |
EP85108623A EP0170926B1 (de) | 1984-07-11 | 1985-07-11 | In der 9- oder 11-Stellung eine, gegebenenfalls substituierte, Aminogruppe aufweisende Eburnancarbonsäurederivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel |
ZA855245A ZA855245B (en) | 1984-07-11 | 1985-07-11 | Aminoeburnanecarboxylic acid derivatives,pharmaceutical compositions containing them and process for preparing same |
DK317985A DK317985A (da) | 1984-07-11 | 1985-07-11 | Aminoeburnancarboxylsyrederivater |
GR851723A GR851723B (de) | 1984-07-11 | 1985-07-11 | |
AT85108623T ATE50576T1 (de) | 1984-07-11 | 1985-07-11 | In der 9- oder 11-stellung eine, gegebenenfalls substituierte, aminogruppe aufweisende eburnancarbonsaeurederivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel. |
JP60151430A JPS6150981A (ja) | 1984-07-11 | 1985-07-11 | エブルナンカルボン酸誘導体及びその製造方法並びにこの誘導体を含有する医薬組成物 |
NZ212713A NZ212713A (en) | 1984-07-11 | 1985-07-11 | Vincaminate derivatives and pharmaceutical compositions |
CS855186A CS255889B2 (en) | 1984-07-11 | 1985-07-11 | Process for preparing new racemic and optical active derivatives of 9-and 11-aminoeburnancarboxylic acid |
NO852795A NO852795L (no) | 1984-07-11 | 1985-07-11 | Fremgangsmaate for fremstilling av aminoeburnankarboksylsyre-derivater. |
KR1019850004954A KR860001111A (ko) | 1984-07-11 | 1985-07-11 | 아미노 에부르난 카르복실산 유도체의 제조방법 |
ES545116A ES545116A0 (es) | 1984-07-11 | 1985-07-11 | Procedimiento para la preparacion de nuevos derivados race- micos y opticamente activos del acido 9- y 11-aminoeburnano-carboxilico |
IL75775A IL75775A0 (en) | 1984-07-11 | 1985-07-11 | Aminoeburnanecarboxylic acid derivatives,their preparation and pharmaceutical compositions containing them |
SU853923279A SU1428200A3 (ru) | 1984-07-11 | 1985-07-11 | Способ получени рацемических или оптически активных производных 9- или 11-аминоэбурнанкарбоновой кислоты или их кислотно-аддитивных солей |
DE8585108623T DE3576159D1 (de) | 1984-07-11 | 1985-07-11 | In der 9- oder 11-stellung eine, gegebenenfalls substituierte, aminogruppe aufweisende eburnancarbonsaeurederivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU842703A HU191694B (en) | 1984-07-11 | 1984-07-11 | Process for production of new derivatives of amineburnan carbonic acid |
Publications (2)
Publication Number | Publication Date |
---|---|
HUT38101A HUT38101A (en) | 1986-04-28 |
HU191694B true HU191694B (en) | 1987-03-30 |
Family
ID=10960716
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU842703A HU191694B (en) | 1984-07-11 | 1984-07-11 | Process for production of new derivatives of amineburnan carbonic acid |
Country Status (18)
Country | Link |
---|---|
JP (1) | JPS6150981A (de) |
KR (1) | KR860001111A (de) |
AU (1) | AU577393B2 (de) |
CS (1) | CS255889B2 (de) |
DD (1) | DD235646A5 (de) |
DK (1) | DK317985A (de) |
ES (1) | ES545116A0 (de) |
FI (1) | FI852750L (de) |
GR (1) | GR851723B (de) |
HU (1) | HU191694B (de) |
IL (1) | IL75775A0 (de) |
NO (1) | NO852795L (de) |
NZ (1) | NZ212713A (de) |
PL (1) | PL254496A1 (de) |
PT (1) | PT80799B (de) |
SU (1) | SU1428200A3 (de) |
YU (1) | YU115385A (de) |
ZA (1) | ZA855245B (de) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU191938B (en) * | 1984-07-11 | 1987-04-28 | Andras Vedres | Process for production of new derivatives of 9 and 11 nitro-apovincamin acid |
HU191693B (en) * | 1984-07-11 | 1987-03-30 | Richter Gedeon Vegyeszet | Process for production of derivatives of 9-or-11 substituated apovincamin acid |
FR2623501B1 (fr) * | 1987-11-19 | 1990-03-16 | Roussel Uclaf | Nouveaux derives substitues de 20,21-dinoreburnamenine, leur procede de preparation et les nouveaux intermediaires ainsi obtenus, leur application comme medicaments et les compositions pharmaceutiques les renfermant |
CA2238488A1 (en) * | 1994-07-07 | 1997-06-05 | Hiroyoshi Hidaka | Apovincaminic acid derivatives and drugs containing the same |
US10017507B2 (en) * | 2015-02-04 | 2018-07-10 | Harbin Pharmaceutical Group Co., Ltd. General Pharmaceutical Factory | Diaza-benzofluoranthrene compounds |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU191938B (en) * | 1984-07-11 | 1987-04-28 | Andras Vedres | Process for production of new derivatives of 9 and 11 nitro-apovincamin acid |
-
1984
- 1984-07-11 HU HU842703A patent/HU191694B/hu not_active IP Right Cessation
-
1985
- 1985-07-10 AU AU44770/85A patent/AU577393B2/en not_active Ceased
- 1985-07-11 SU SU853923279A patent/SU1428200A3/ru active
- 1985-07-11 CS CS855186A patent/CS255889B2/cs unknown
- 1985-07-11 NO NO852795A patent/NO852795L/no unknown
- 1985-07-11 IL IL75775A patent/IL75775A0/xx unknown
- 1985-07-11 DK DK317985A patent/DK317985A/da not_active Application Discontinuation
- 1985-07-11 FI FI852750A patent/FI852750L/fi not_active Application Discontinuation
- 1985-07-11 KR KR1019850004954A patent/KR860001111A/ko not_active Application Discontinuation
- 1985-07-11 GR GR851723A patent/GR851723B/el unknown
- 1985-07-11 NZ NZ212713A patent/NZ212713A/en unknown
- 1985-07-11 ES ES545116A patent/ES545116A0/es active Granted
- 1985-07-11 YU YU01153/85A patent/YU115385A/xx unknown
- 1985-07-11 DD DD85278517A patent/DD235646A5/de not_active IP Right Cessation
- 1985-07-11 PL PL25449685A patent/PL254496A1/xx unknown
- 1985-07-11 JP JP60151430A patent/JPS6150981A/ja active Pending
- 1985-07-11 ZA ZA855245A patent/ZA855245B/xx unknown
- 1985-07-11 PT PT80799A patent/PT80799B/pt unknown
Also Published As
Publication number | Publication date |
---|---|
KR860001111A (ko) | 1986-02-22 |
DD235646A5 (de) | 1986-05-14 |
JPS6150981A (ja) | 1986-03-13 |
PT80799A (en) | 1985-08-01 |
IL75775A0 (en) | 1985-11-29 |
GR851723B (de) | 1986-02-28 |
HUT38101A (en) | 1986-04-28 |
PL254496A1 (en) | 1988-07-21 |
PT80799B (en) | 1987-01-12 |
SU1428200A3 (ru) | 1988-09-30 |
YU115385A (en) | 1988-04-30 |
DK317985D0 (da) | 1985-07-11 |
AU4477085A (en) | 1986-01-16 |
ZA855245B (en) | 1986-02-26 |
CS255889B2 (en) | 1988-03-15 |
DK317985A (da) | 1986-01-12 |
ES8603880A1 (es) | 1986-01-01 |
NZ212713A (en) | 1988-03-30 |
NO852795L (no) | 1986-01-13 |
ES545116A0 (es) | 1986-01-01 |
FI852750L (fi) | 1986-01-12 |
AU577393B2 (en) | 1988-09-22 |
FI852750A0 (fi) | 1985-07-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
HU90 | Patent valid on 900628 | ||
HMM4 | Cancellation of final prot. due to non-payment of fee |