HU191694B - Process for production of new derivatives of amineburnan carbonic acid - Google Patents

Process for production of new derivatives of amineburnan carbonic acid Download PDF

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Publication number
HU191694B
HU191694B HU842703A HU270384A HU191694B HU 191694 B HU191694 B HU 191694B HU 842703 A HU842703 A HU 842703A HU 270384 A HU270384 A HU 270384A HU 191694 B HU191694 B HU 191694B
Authority
HU
Hungary
Prior art keywords
amino
formula
hydrogen
acid
group
Prior art date
Application number
HU842703A
Other languages
English (en)
Hungarian (hu)
Other versions
HUT38101A (en
Inventor
Andras Vedres
Csaba Szantay
Istvan Moldvai
Bela Stefko
Dora Groo
Egon Karpati
Bela Kiss
Erzsebet Lapis
Istvan Laszlovszky
Eva Palosi
Miklos Riesz
Zsolt Szombathelyi
Laszlo Szporny
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Priority to HU842703A priority Critical patent/HU191694B/hu
Priority to AU44770/85A priority patent/AU577393B2/en
Priority to PL25449685A priority patent/PL254496A1/xx
Priority to FI852750A priority patent/FI852750L/fi
Priority to YU01153/85A priority patent/YU115385A/xx
Priority to DD85278517A priority patent/DD235646A5/de
Priority to PT80799A priority patent/PT80799B/pt
Priority to EP85108623A priority patent/EP0170926B1/de
Priority to ZA855245A priority patent/ZA855245B/xx
Priority to DK317985A priority patent/DK317985A/da
Priority to GR851723A priority patent/GR851723B/el
Priority to AT85108623T priority patent/ATE50576T1/de
Priority to JP60151430A priority patent/JPS6150981A/ja
Priority to NZ212713A priority patent/NZ212713A/en
Priority to CS855186A priority patent/CS255889B2/cs
Priority to NO852795A priority patent/NO852795L/no
Priority to KR1019850004954A priority patent/KR860001111A/ko
Priority to ES545116A priority patent/ES545116A0/es
Priority to IL75775A priority patent/IL75775A0/xx
Priority to SU853923279A priority patent/SU1428200A3/ru
Priority to DE8585108623T priority patent/DE3576159D1/de
Publication of HUT38101A publication Critical patent/HUT38101A/hu
Publication of HU191694B publication Critical patent/HU191694B/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06—Peri-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cephalosporin Compounds (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Fats And Perfumes (AREA)

Abstract

Die Erfindung betrifft ein Verfahren zur Herstellung von neuen, in der 9- oder 11-Stellung eine gegebenenfalls substituierte Aminogruppe enthaltenden Eburnancarbonsaeure-Derivaten, von ihren optischen aktiven Isomeren und ihren Salze. Die neuen Verbindungen entsprechen der allgemeinen Formel (I), worin R fuer eine Aminogruppe oder eine Gruppe der allgemeinen Formel -NH-COR1 steht, worin R1 z. B. Wasserstoff, eine cycloaliphatische Kohlenwasserstoffgruppe mit 3.8 Kohlenstoffatomen oder eine aromatische Kohlenwasserstoffgruppe mit 6-14 Kohlenstoffatomen oder eine Gruppe -NH-SO2R2 steht, worin R2 z. B. eine gegebenenfalls substituierte aliphatische Kohlenwasserstoffgruppe mit 1-10 Kohlenstoffatomen ist, R3 z. B. fuer Wasserstoff oder eine gegebenenfalls substituierte Kohlenwasserstoffgruppe mit 1-10 Kohlenstoffatomen steht. A eine Hydroxylgruppe und B Wasserstoff bedeutet oder A und B gemeinsam eine chemische Bindung bilden. Die Verbindungen der allgemeinen Formel (I) weisen wertvolle pharmakologische Wirkungen auf. Die Herstellung der Verbindungen erfolgt gemaess Analogieverfahren in an sich bekannter Weise. Weitere Bedeutungen der Substituenten sind dem Anspruch 1 zu entnehmen. Formel I
HU842703A 1984-07-11 1984-07-11 Process for production of new derivatives of amineburnan carbonic acid HU191694B (en)

Priority Applications (21)

Application Number Priority Date Filing Date Title
HU842703A HU191694B (en) 1984-07-11 1984-07-11 Process for production of new derivatives of amineburnan carbonic acid
AU44770/85A AU577393B2 (en) 1984-07-11 1985-07-10 Apovincamine or vincamine derivatives
PL25449685A PL254496A1 (en) 1984-07-11 1985-07-11 A method of aminoeburano-carboxyl acid production
FI852750A FI852750L (fi) 1984-07-11 1985-07-11 Foerfarande foer framstaellning aminoeburnankarboxylsyraderivat.
YU01153/85A YU115385A (en) 1984-07-11 1985-07-11 Process for obtaining derivatives of aminoeburnancarbonic acid
DD85278517A DD235646A5 (de) 1984-07-11 1985-07-11 Verfahren zur herstellung von neuen aminoeburnancarbonsaeure-derivaten
PT80799A PT80799B (en) 1984-07-11 1985-07-11 Aminoeburnanecarboxylic acid derivatives pharmaceutical compositions containing them and process for preparing same
EP85108623A EP0170926B1 (de) 1984-07-11 1985-07-11 In der 9- oder 11-Stellung eine, gegebenenfalls substituierte, Aminogruppe aufweisende Eburnancarbonsäurederivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
ZA855245A ZA855245B (en) 1984-07-11 1985-07-11 Aminoeburnanecarboxylic acid derivatives,pharmaceutical compositions containing them and process for preparing same
DK317985A DK317985A (da) 1984-07-11 1985-07-11 Aminoeburnancarboxylsyrederivater
GR851723A GR851723B (de) 1984-07-11 1985-07-11
AT85108623T ATE50576T1 (de) 1984-07-11 1985-07-11 In der 9- oder 11-stellung eine, gegebenenfalls substituierte, aminogruppe aufweisende eburnancarbonsaeurederivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel.
JP60151430A JPS6150981A (ja) 1984-07-11 1985-07-11 エブルナンカルボン酸誘導体及びその製造方法並びにこの誘導体を含有する医薬組成物
NZ212713A NZ212713A (en) 1984-07-11 1985-07-11 Vincaminate derivatives and pharmaceutical compositions
CS855186A CS255889B2 (en) 1984-07-11 1985-07-11 Process for preparing new racemic and optical active derivatives of 9-and 11-aminoeburnancarboxylic acid
NO852795A NO852795L (no) 1984-07-11 1985-07-11 Fremgangsmaate for fremstilling av aminoeburnankarboksylsyre-derivater.
KR1019850004954A KR860001111A (ko) 1984-07-11 1985-07-11 아미노 에부르난 카르복실산 유도체의 제조방법
ES545116A ES545116A0 (es) 1984-07-11 1985-07-11 Procedimiento para la preparacion de nuevos derivados race- micos y opticamente activos del acido 9- y 11-aminoeburnano-carboxilico
IL75775A IL75775A0 (en) 1984-07-11 1985-07-11 Aminoeburnanecarboxylic acid derivatives,their preparation and pharmaceutical compositions containing them
SU853923279A SU1428200A3 (ru) 1984-07-11 1985-07-11 Способ получени рацемических или оптически активных производных 9- или 11-аминоэбурнанкарбоновой кислоты или их кислотно-аддитивных солей
DE8585108623T DE3576159D1 (de) 1984-07-11 1985-07-11 In der 9- oder 11-stellung eine, gegebenenfalls substituierte, aminogruppe aufweisende eburnancarbonsaeurederivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU842703A HU191694B (en) 1984-07-11 1984-07-11 Process for production of new derivatives of amineburnan carbonic acid

Publications (2)

Publication Number Publication Date
HUT38101A HUT38101A (en) 1986-04-28
HU191694B true HU191694B (en) 1987-03-30

Family

ID=10960716

Family Applications (1)

Application Number Title Priority Date Filing Date
HU842703A HU191694B (en) 1984-07-11 1984-07-11 Process for production of new derivatives of amineburnan carbonic acid

Country Status (18)

Country Link
JP (1) JPS6150981A (de)
KR (1) KR860001111A (de)
AU (1) AU577393B2 (de)
CS (1) CS255889B2 (de)
DD (1) DD235646A5 (de)
DK (1) DK317985A (de)
ES (1) ES545116A0 (de)
FI (1) FI852750L (de)
GR (1) GR851723B (de)
HU (1) HU191694B (de)
IL (1) IL75775A0 (de)
NO (1) NO852795L (de)
NZ (1) NZ212713A (de)
PL (1) PL254496A1 (de)
PT (1) PT80799B (de)
SU (1) SU1428200A3 (de)
YU (1) YU115385A (de)
ZA (1) ZA855245B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU191938B (en) * 1984-07-11 1987-04-28 Andras Vedres Process for production of new derivatives of 9 and 11 nitro-apovincamin acid
HU191693B (en) * 1984-07-11 1987-03-30 Richter Gedeon Vegyeszet Process for production of derivatives of 9-or-11 substituated apovincamin acid
FR2623501B1 (fr) * 1987-11-19 1990-03-16 Roussel Uclaf Nouveaux derives substitues de 20,21-dinoreburnamenine, leur procede de preparation et les nouveaux intermediaires ainsi obtenus, leur application comme medicaments et les compositions pharmaceutiques les renfermant
CA2238488A1 (en) * 1994-07-07 1997-06-05 Hiroyoshi Hidaka Apovincaminic acid derivatives and drugs containing the same
US10017507B2 (en) * 2015-02-04 2018-07-10 Harbin Pharmaceutical Group Co., Ltd. General Pharmaceutical Factory Diaza-benzofluoranthrene compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU191938B (en) * 1984-07-11 1987-04-28 Andras Vedres Process for production of new derivatives of 9 and 11 nitro-apovincamin acid

Also Published As

Publication number Publication date
KR860001111A (ko) 1986-02-22
DD235646A5 (de) 1986-05-14
JPS6150981A (ja) 1986-03-13
PT80799A (en) 1985-08-01
IL75775A0 (en) 1985-11-29
GR851723B (de) 1986-02-28
HUT38101A (en) 1986-04-28
PL254496A1 (en) 1988-07-21
PT80799B (en) 1987-01-12
SU1428200A3 (ru) 1988-09-30
YU115385A (en) 1988-04-30
DK317985D0 (da) 1985-07-11
AU4477085A (en) 1986-01-16
ZA855245B (en) 1986-02-26
CS255889B2 (en) 1988-03-15
DK317985A (da) 1986-01-12
ES8603880A1 (es) 1986-01-01
NZ212713A (en) 1988-03-30
NO852795L (no) 1986-01-13
ES545116A0 (es) 1986-01-01
FI852750L (fi) 1986-01-12
AU577393B2 (en) 1988-09-22
FI852750A0 (fi) 1985-07-11

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Legal Events

Date Code Title Description
HU90 Patent valid on 900628
HMM4 Cancellation of final prot. due to non-payment of fee