HU183046B - Process for producing hydanthoine derivatives - Google Patents

Process for producing hydanthoine derivatives Download PDF

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Publication number
HU183046B
HU183046B HU77WE560A HUWE000560A HU183046B HU 183046 B HU183046 B HU 183046B HU 77WE560 A HU77WE560 A HU 77WE560A HU WE000560 A HUWE000560 A HU WE000560A HU 183046 B HU183046 B HU 183046B
Authority
HU
Hungary
Prior art keywords
formula
priority
compound
reaction
june
Prior art date
Application number
HU77WE560A
Other languages
English (en)
Hungarian (hu)
Inventor
Albert G Caldwell
Norman Whittaker
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of HU183046B publication Critical patent/HU183046B/hu

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10Oxygen atoms
    • C07D309/12Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72Two oxygen atoms, e.g. hydantoin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72Two oxygen atoms, e.g. hydantoin
    • C07D233/76Two oxygen atoms, e.g. hydantoin with substituted hydrocarbon radicals attached to the third ring carbon atom
    • C07D233/78Radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/86Oxygen and sulfur atoms, e.g. thiohydantoin

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
HU77WE560A 1976-06-03 1977-06-02 Process for producing hydanthoine derivatives HU183046B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB2287776 1976-06-03
GB5034076 1976-12-02
GB1214577 1977-03-23

Publications (1)

Publication Number Publication Date
HU183046B true HU183046B (en) 1984-04-28

Family

ID=27256793

Family Applications (1)

Application Number Title Priority Date Filing Date
HU77WE560A HU183046B (en) 1976-06-03 1977-06-02 Process for producing hydanthoine derivatives

Country Status (12)

Country Link
JP (1) JPS52151168A (US06168776-20010102-C00041.png)
CA (1) CA1176261A (US06168776-20010102-C00041.png)
CH (3) CH645631A5 (US06168776-20010102-C00041.png)
DE (1) DE2724948A1 (US06168776-20010102-C00041.png)
DK (1) DK244577A (US06168776-20010102-C00041.png)
ES (5) ES459412A1 (US06168776-20010102-C00041.png)
FI (1) FI71930C (US06168776-20010102-C00041.png)
FR (1) FR2362839A1 (US06168776-20010102-C00041.png)
HU (1) HU183046B (US06168776-20010102-C00041.png)
NL (1) NL7706064A (US06168776-20010102-C00041.png)
NZ (1) NZ184281A (US06168776-20010102-C00041.png)
SE (2) SE446336B (US06168776-20010102-C00041.png)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1602188A (en) * 1977-12-01 1981-11-11 Wellcome Found Hydantoin derivatives
FI782717A (fi) * 1977-09-05 1979-03-06 Wellcome Found Biologiskt aktiva n-heterocykler deras syntes och anvaendning i mediciner
ZA786739B (en) * 1977-12-01 1980-07-30 Wellcome Found Hydantoin derivatives and salts thereof,their syntheses,and intermediates,and pharmaceutical formulations
DE2963795D1 (en) * 1978-01-23 1982-11-11 Beecham Group Plc Hydantoins and thiohydantoins, method for their preparation and pharmaceutical compositions containing them
EP0004723A1 (en) * 1978-03-30 1979-10-17 Beecham Group Plc Deoxyhydantoins, processes for their preparation and pharmaceutical compositions containing them
GB1599740A (en) * 1978-05-31 1981-10-07 Wellcome Found Hydantoin derivatives
DE2965099D1 (en) * 1978-06-15 1983-05-05 Beecham Group Plc Prostaglandin analogue triazole derivatives, processes for their preparation and a pharmaceutical composition containing them
IL57504A0 (en) * 1978-06-15 1979-10-31 Beecham Group Ltd Prostagandin analogues,their preparation and pharmaceutical compositions containing
EP0006352A1 (en) * 1978-06-15 1980-01-09 Beecham Group Plc Hydantoins and thiohydantoins, process for their preparation and pharmaceutical compositions containing them
AU4778279A (en) * 1978-06-15 1979-12-20 Beecham Group Limited Prostaglandin analogues
IL59065A0 (en) 1979-01-18 1980-05-30 Beecham Group Ltd Hydantoin derivatives,their preparation pharmaceutical compositons containing them
JPS55151569A (en) * 1979-05-09 1980-11-26 Wellcome Found Optically active heterocyclic compounds* their synthesis and medical blend containing them
US4684735A (en) * 1985-07-01 1987-08-04 Stauffer Chemical Company Promotion of raney nickel hydrogenation catalyst
JP3022878U (ja) * 1995-08-18 1996-04-02 有限会社春江加工 ミニディスク用ケース
KR20050044606A (ko) 2001-11-30 2005-05-12 일라이 릴리 앤드 캄파니 퍼옥시솜 증식제에 의해 활성화된 수용체 아고니스트
EP1631355B1 (en) * 2003-06-06 2014-08-13 Allergan, Inc. Piperidinyl prostaglandin e analogs
US7179820B2 (en) * 2003-06-06 2007-02-20 Allergan, Inc. Piperidinyl prostaglandin E analogs

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1524818A (en) * 1974-11-29 1978-09-13 Beecham Group Ltd 12-azaprostaglandins

Also Published As

Publication number Publication date
FR2362839A1 (fr) 1978-03-24
ES8103057A1 (es) 1981-02-16
JPS52151168A (en) 1977-12-15
ES459412A1 (es) 1978-11-01
FI71930B (fi) 1986-11-28
ES478156A1 (es) 1979-11-01
CH647511A5 (en) 1985-01-31
ES470428A1 (es) 1979-09-01
CH645631A5 (en) 1984-10-15
FR2362839B1 (US06168776-20010102-C00041.png) 1980-02-01
FI71930C (fi) 1987-03-09
DK244577A (da) 1977-12-04
CA1176261A (en) 1984-10-16
ES489883A0 (es) 1981-02-16
SE446336B (sv) 1986-09-01
CH646426A5 (en) 1984-11-30
DE2724948A1 (de) 1977-12-15
SE8203161L (sv) 1982-05-19
SE7706428L (sv) 1977-12-04
JPS6222986B2 (US06168776-20010102-C00041.png) 1987-05-20
FI771763A (fi) 1977-12-04
ES482010A1 (es) 1980-08-16
NL7706064A (nl) 1977-12-06
NZ184281A (en) 1980-04-28

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