FI782717A - Biologiskt aktiva n-heterocykler deras syntes och anvaendning i mediciner - Google Patents

Biologiskt aktiva n-heterocykler deras syntes och anvaendning i mediciner

Info

Publication number
FI782717A
FI782717A FI782717A FI782717A FI782717A FI 782717 A FI782717 A FI 782717A FI 782717 A FI782717 A FI 782717A FI 782717 A FI782717 A FI 782717A FI 782717 A FI782717 A FI 782717A
Authority
FI
Finland
Prior art keywords
mediciner
heterocycler
syntes
deras
biologically active
Prior art date
Application number
FI782717A
Other languages
English (en)
Inventor
Norman Whittaker
Albert Gordon Caldwell
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB37054/77A external-priority patent/GB1603407A/en
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of FI782717A publication Critical patent/FI782717A/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72Two oxygen atoms, e.g. hydantoin
    • C07D233/76Two oxygen atoms, e.g. hydantoin with substituted hydrocarbon radicals attached to the third ring carbon atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72Two oxygen atoms, e.g. hydantoin
    • C07D233/76Two oxygen atoms, e.g. hydantoin with substituted hydrocarbon radicals attached to the third ring carbon atom
    • C07D233/78Radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/90Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI782717A 1977-09-05 1978-09-05 Biologiskt aktiva n-heterocykler deras syntes och anvaendning i mediciner FI782717A (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB37054/77A GB1603407A (en) 1977-09-05 1977-09-05 Hydantoin derivatives
GB5009277 1977-12-01

Publications (1)

Publication Number Publication Date
FI782717A true FI782717A (fi) 1979-03-06

Family

ID=26263318

Family Applications (1)

Application Number Title Priority Date Filing Date
FI782717A FI782717A (fi) 1977-09-05 1978-09-05 Biologiskt aktiva n-heterocykler deras syntes och anvaendning i mediciner

Country Status (9)

Country Link
EP (1) EP0001238B1 (fi)
JP (1) JPS5463083A (fi)
AT (1) AT372681B (fi)
AU (1) AU527959B2 (fi)
CA (1) CA1150250A (fi)
DK (1) DK391678A (fi)
FI (1) FI782717A (fi)
IE (1) IE48747B1 (fi)
SU (1) SU1005658A3 (fi)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1599740A (en) * 1978-05-31 1981-10-07 Wellcome Found Hydantoin derivatives
EP0007180B1 (en) * 1978-06-15 1983-03-30 Beecham Group Plc Prostaglandin analogue triazole derivatives, processes for their preparation and a pharmaceutical composition containing them
IL57504A0 (en) * 1978-06-15 1979-10-31 Beecham Group Ltd Prostagandin analogues,their preparation and pharmaceutical compositions containing
EP0006352A1 (en) * 1978-06-15 1980-01-09 Beecham Group Plc Hydantoins and thiohydantoins, process for their preparation and pharmaceutical compositions containing them
AU4778279A (en) * 1978-06-15 1979-12-20 Beecham Group Limited Prostaglandin analogues
IL59065A0 (en) * 1979-01-18 1980-05-30 Beecham Group Ltd Hydantoin derivatives,their preparation pharmaceutical compositons containing them
EP0023083A1 (en) * 1979-06-27 1981-01-28 Beecham Group Plc Oxodiazole derivatives, processes for their production and pharmaceutical composition containing them
CA1268107A (en) * 1984-07-19 1990-04-24 Alfred Fuller Leatherman Thermoset bonding agent for non-distortion joining of self-supporting thermoset component parts

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2138225A1 (de) * 1971-07-30 1973-02-08 Diamalt Ag Hydantoinderivate
FR2362839A1 (fr) * 1976-06-03 1978-03-24 Wellcome Found Derives de l'hydantoine et medicaments contenant ces substances

Also Published As

Publication number Publication date
AU527959B2 (en) 1983-03-31
JPS5463083A (en) 1979-05-21
SU1005658A3 (ru) 1983-03-15
EP0001238A1 (en) 1979-04-04
IE48747B1 (en) 1985-05-15
ATA641378A (de) 1983-03-15
IE781794L (en) 1979-03-05
EP0001238B1 (en) 1984-07-04
AU3955678A (en) 1980-03-13
CA1150250A (en) 1983-07-19
AT372681B (de) 1983-11-10
DK391678A (da) 1979-03-06

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