HU180266B - Process for enhancing the stability of streptomyces cell agregate - Google Patents
Process for enhancing the stability of streptomyces cell agregate Download PDFInfo
- Publication number
- HU180266B HU180266B HU79MI648A HUMI000648A HU180266B HU 180266 B HU180266 B HU 180266B HU 79MI648 A HU79MI648 A HU 79MI648A HU MI000648 A HUMI000648 A HU MI000648A HU 180266 B HU180266 B HU 180266B
- Authority
- HU
- Hungary
- Prior art keywords
- cell aggregate
- streptomyces
- streptomyces cell
- dried
- aggregate
- Prior art date
Links
- 241000187747 Streptomyces Species 0.000 title claims description 34
- 238000000034 method Methods 0.000 title claims description 33
- 230000002708 enhancing effect Effects 0.000 title 1
- 230000001580 bacterial effect Effects 0.000 claims abstract description 49
- 230000015572 biosynthetic process Effects 0.000 claims abstract description 6
- 229920000768 polyamine Polymers 0.000 claims description 25
- 239000003431 cross linking reagent Substances 0.000 claims description 19
- 239000000203 mixture Substances 0.000 claims description 18
- SXRSQZLOMIGNAQ-UHFFFAOYSA-N Glutaraldehyde Chemical compound O=CCCCC=O SXRSQZLOMIGNAQ-UHFFFAOYSA-N 0.000 claims description 17
- -1 cyanuric acid halide Chemical class 0.000 claims description 17
- 239000002245 particle Substances 0.000 claims description 17
- 239000000047 product Substances 0.000 claims description 12
- 150000001875 compounds Chemical class 0.000 claims description 9
- 229920006317 cationic polymer Polymers 0.000 claims description 5
- 239000011541 reaction mixture Substances 0.000 claims description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 5
- 241000218589 Streptomyces olivaceus Species 0.000 claims description 4
- 239000007795 chemical reaction product Substances 0.000 claims description 3
- 238000004519 manufacturing process Methods 0.000 claims description 2
- 150000001299 aldehydes Chemical class 0.000 claims 1
- 241000894007 species Species 0.000 claims 1
- 238000007493 shaping process Methods 0.000 abstract description 2
- 239000000523 sample Substances 0.000 description 22
- 229920000642 polymer Polymers 0.000 description 18
- 239000000843 powder Substances 0.000 description 14
- 230000000694 effects Effects 0.000 description 12
- 102000004190 Enzymes Human genes 0.000 description 10
- 108090000790 Enzymes Proteins 0.000 description 10
- 108700040099 Xylose isomerases Proteins 0.000 description 9
- 238000006243 chemical reaction Methods 0.000 description 7
- 238000001125 extrusion Methods 0.000 description 7
- 238000000855 fermentation Methods 0.000 description 7
- 230000004151 fermentation Effects 0.000 description 7
- 230000006835 compression Effects 0.000 description 6
- 238000007906 compression Methods 0.000 description 6
- 239000007787 solid Substances 0.000 description 6
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 5
- 239000008103 glucose Substances 0.000 description 5
- 125000003277 amino group Chemical group 0.000 description 4
- 239000000428 dust Substances 0.000 description 4
- 238000001914 filtration Methods 0.000 description 4
- 239000000463 material Substances 0.000 description 4
- 230000035515 penetration Effects 0.000 description 4
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 description 3
- 125000002947 alkylene group Chemical group 0.000 description 3
- 125000002091 cationic group Chemical group 0.000 description 3
- 239000012153 distilled water Substances 0.000 description 3
- 238000009826 distribution Methods 0.000 description 3
- 230000002255 enzymatic effect Effects 0.000 description 3
- 229960002737 fructose Drugs 0.000 description 3
- 125000005843 halogen group Chemical group 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 238000006116 polymerization reaction Methods 0.000 description 3
- 238000002360 preparation method Methods 0.000 description 3
- 239000004925 Acrylic resin Substances 0.000 description 2
- 229920000178 Acrylic resin Polymers 0.000 description 2
- 229930091371 Fructose Natural products 0.000 description 2
- 239000005715 Fructose Substances 0.000 description 2
- 230000004931 aggregating effect Effects 0.000 description 2
- 238000004220 aggregation Methods 0.000 description 2
- 230000002776 aggregation Effects 0.000 description 2
- 239000013068 control sample Substances 0.000 description 2
- MGNCLNQXLYJVJD-UHFFFAOYSA-N cyanuric chloride Chemical compound ClC1=NC(Cl)=NC(Cl)=N1 MGNCLNQXLYJVJD-UHFFFAOYSA-N 0.000 description 2
- 239000008394 flocculating agent Substances 0.000 description 2
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 2
- 150000002367 halogens Chemical group 0.000 description 2
- 230000002779 inactivation Effects 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 244000005700 microbiome Species 0.000 description 2
- 229920000867 polyelectrolyte Polymers 0.000 description 2
- 238000009987 spinning Methods 0.000 description 2
- 238000003860 storage Methods 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 description 1
- 239000010963 304 stainless steel Substances 0.000 description 1
- 241000193749 Bacillus coagulans Species 0.000 description 1
- 229920001503 Glucan Polymers 0.000 description 1
- 108090000769 Isomerases Proteins 0.000 description 1
- 102000004195 Isomerases Human genes 0.000 description 1
- 240000002129 Malva sylvestris Species 0.000 description 1
- 235000006770 Malva sylvestris Nutrition 0.000 description 1
- 229910000589 SAE 304 stainless steel Inorganic materials 0.000 description 1
- 229910000831 Steel Inorganic materials 0.000 description 1
- 241000187759 Streptomyces albus Species 0.000 description 1
- 241000509474 Streptomyces flavovirens Species 0.000 description 1
- GPWHDDKQSYOYBF-UHFFFAOYSA-N ac1l2u0q Chemical compound Br[Br-]Br GPWHDDKQSYOYBF-UHFFFAOYSA-N 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 238000005273 aeration Methods 0.000 description 1
- 125000000129 anionic group Chemical group 0.000 description 1
- 229940054340 bacillus coagulans Drugs 0.000 description 1
- 239000011230 binding agent Substances 0.000 description 1
- 239000000872 buffer Substances 0.000 description 1
- 206010061592 cardiac fibrillation Diseases 0.000 description 1
- 230000001413 cellular effect Effects 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- 235000013351 cheese Nutrition 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000005056 compaction Methods 0.000 description 1
- 238000004132 cross linking Methods 0.000 description 1
- 238000012258 culturing Methods 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 239000008121 dextrose Substances 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 230000002600 fibrillogenic effect Effects 0.000 description 1
- 230000003311 flocculating effect Effects 0.000 description 1
- 229910052736 halogen Inorganic materials 0.000 description 1
- 230000036571 hydration Effects 0.000 description 1
- 238000006703 hydration reaction Methods 0.000 description 1
- 230000003100 immobilizing effect Effects 0.000 description 1
- 150000002736 metal compounds Chemical class 0.000 description 1
- FEMOMIGRRWSMCU-UHFFFAOYSA-N ninhydrin Chemical compound C1=CC=C2C(=O)C(O)(O)C(=O)C2=C1 FEMOMIGRRWSMCU-UHFFFAOYSA-N 0.000 description 1
- 239000011236 particulate material Substances 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 239000000376 reactant Substances 0.000 description 1
- 239000012429 reaction media Substances 0.000 description 1
- 230000035484 reaction time Effects 0.000 description 1
- 239000002002 slurry Substances 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 239000010959 steel Substances 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000004753 textile Substances 0.000 description 1
- WRTMQOHKMFDUKX-UHFFFAOYSA-N triiodide Chemical compound I[I-]I WRTMQOHKMFDUKX-UHFFFAOYSA-N 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/24—Preparation of compounds containing saccharide radicals produced by the action of an isomerase, e.g. fructose
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
- C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
- C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
- C12N11/089—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
- C12N11/091—Phenol resins; Amino resins
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/886—Streptomyces
- Y10S435/902—Streptomyces olivaceus
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Bakery Products And Manufacturing Methods Therefor (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/941,152 US4251632A (en) | 1978-09-11 | 1978-09-11 | Preparation of a bacterial cell aggregate |
Publications (1)
Publication Number | Publication Date |
---|---|
HU180266B true HU180266B (en) | 1983-02-28 |
Family
ID=25476013
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU79MI648A HU180266B (en) | 1978-09-11 | 1979-04-11 | Process for enhancing the stability of streptomyces cell agregate |
Country Status (19)
Country | Link |
---|---|
US (1) | US4251632A (en, 2012) |
JP (1) | JPS5539793A (en, 2012) |
AR (1) | AR225283A1 (en, 2012) |
AU (1) | AU514883B2 (en, 2012) |
BE (1) | BE876083A (en, 2012) |
CA (1) | CA1110186A (en, 2012) |
DE (1) | DE2936486C2 (en, 2012) |
DK (1) | DK151638C (en, 2012) |
ES (1) | ES479854A1 (en, 2012) |
FR (1) | FR2435525A1 (en, 2012) |
GB (1) | GB2029856B (en, 2012) |
HU (1) | HU180266B (en, 2012) |
IL (1) | IL56952A0 (en, 2012) |
IT (1) | IT1120423B (en, 2012) |
NL (1) | NL188952C (en, 2012) |
NO (1) | NO792916L (en, 2012) |
PL (1) | PL216816A1 (en, 2012) |
SE (1) | SE7903700L (en, 2012) |
YU (1) | YU44406B (en, 2012) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4411795A (en) * | 1980-03-10 | 1983-10-25 | Baxter Travenol Laboratories, Inc. | Particle adsorption |
DE3038219A1 (de) * | 1980-10-09 | 1982-04-15 | Süddeutsche Zucker AG, 6800 Mannheim | Verfahren zur herstellung von isomaltulose (6-o-(alpha)-d-glucopyranosido-d-fructose) mit hilfe von immobilisierten bakterienzellen |
US4337313A (en) * | 1980-12-08 | 1982-06-29 | Miles Laboratories, Inc. | Immobilization of biocatalysts |
CS231458B1 (en) * | 1982-01-14 | 1984-11-19 | Vladimir Vojtisek | Cellular catalysts for biotransformation and method to produce them |
US4543332A (en) * | 1982-03-29 | 1985-09-24 | Miles Laboratories, Inc. | Method for the preparation of spherical microorganism cell aggregates |
JPS58187189A (ja) * | 1982-03-29 | 1983-11-01 | マイルス・ラボラトリ−ス・インコ−ポレ−テツド | 球状の微生物細胞凝集物の製造法 |
US4757008A (en) * | 1986-02-24 | 1988-07-12 | Miles Inc. | Enzyme immobilization in a macroporous non-ionic resin |
JPS6358449U (en, 2012) * | 1986-10-03 | 1988-04-19 | ||
WO2019060501A1 (en) * | 2017-09-21 | 2019-03-28 | Muhammed Majeed | ALCOHOLIC BEVERAGE COMPOSITION CONTAINING BACILLUS COAGULANS |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4060456A (en) * | 1973-01-02 | 1977-11-29 | R. J. Reynolds Tobacco Company | Glucose isomerization process |
-
1978
- 1978-09-11 US US05/941,152 patent/US4251632A/en not_active Expired - Lifetime
-
1979
- 1979-03-22 CA CA323,952A patent/CA1110186A/en not_active Expired
- 1979-03-26 IL IL56952A patent/IL56952A0/xx unknown
- 1979-04-05 AR AR276091A patent/AR225283A1/es active
- 1979-04-11 HU HU79MI648A patent/HU180266B/hu not_active IP Right Cessation
- 1979-04-24 ES ES479854A patent/ES479854A1/es not_active Expired
- 1979-04-26 SE SE7903700A patent/SE7903700L/xx unknown
- 1979-04-27 NL NLAANVRAGE7903379,A patent/NL188952C/xx not_active IP Right Cessation
- 1979-05-04 FR FR7911264A patent/FR2435525A1/fr not_active Withdrawn
- 1979-05-07 BE BE0/195027A patent/BE876083A/xx not_active IP Right Cessation
- 1979-05-21 GB GB7917618A patent/GB2029856B/en not_active Expired
- 1979-05-25 IT IT49183/79A patent/IT1120423B/it active
- 1979-06-08 AU AU47911/79A patent/AU514883B2/en not_active Ceased
- 1979-06-14 JP JP7408379A patent/JPS5539793A/ja active Granted
- 1979-07-03 PL PL21681679A patent/PL216816A1/xx unknown
- 1979-09-05 YU YU2150/79A patent/YU44406B/xx unknown
- 1979-09-10 DE DE2936486A patent/DE2936486C2/de not_active Expired
- 1979-09-10 DK DK377679A patent/DK151638C/da not_active IP Right Cessation
- 1979-09-10 NO NO792916A patent/NO792916L/no unknown
Also Published As
Publication number | Publication date |
---|---|
FR2435525A1 (fr) | 1980-04-04 |
US4251632A (en) | 1981-02-17 |
BE876083A (fr) | 1979-09-03 |
DE2936486A1 (de) | 1980-03-13 |
IL56952A0 (en) | 1979-05-31 |
AU4791179A (en) | 1980-03-20 |
IT7949183A0 (it) | 1979-05-25 |
DE2936486C2 (de) | 1982-10-14 |
JPS5741239B2 (en, 2012) | 1982-09-02 |
DK151638C (da) | 1988-06-20 |
PL216816A1 (en, 2012) | 1980-05-05 |
YU215079A (en) | 1984-04-30 |
NL188952C (nl) | 1992-11-16 |
AU514883B2 (en) | 1981-03-05 |
YU44406B (en) | 1990-08-31 |
CA1110186A (en) | 1981-10-06 |
NL188952B (nl) | 1992-06-16 |
GB2029856A (en) | 1980-03-26 |
ES479854A1 (es) | 1980-08-16 |
SE7903700L (sv) | 1980-03-12 |
DK151638B (da) | 1987-12-21 |
NO792916L (no) | 1980-03-12 |
JPS5539793A (en) | 1980-03-19 |
AR225283A1 (es) | 1982-03-15 |
GB2029856B (en) | 1982-10-20 |
NL7903379A (nl) | 1980-03-13 |
DK377679A (da) | 1980-03-12 |
IT1120423B (it) | 1986-03-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
HU90 | Patent valid on 900628 | ||
HPC4 | Succession in title of patentee |
Owner name: SOLVAY ENZYMES, INC., US |
|
HMM4 | Cancellation of final prot. due to non-payment of fee |