HU180230B - Process for producing dihydro- and hexahydrobenzopyranoxantenones - Google Patents

Process for producing dihydro- and hexahydrobenzopyranoxantenones Download PDF

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Publication number
HU180230B
HU180230B HU78EI777A HUEI000777A HU180230B HU 180230 B HU180230 B HU 180230B HU 78EI777 A HU78EI777 A HU 78EI777A HU EI000777 A HUEI000777 A HU EI000777A HU 180230 B HU180230 B HU 180230B
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HU
Hungary
Prior art keywords
formula
compound
dimethyl
preparation
xanthene
Prior art date
Application number
HU78EI777A
Other languages
English (en)
Hungarian (hu)
Inventor
Michael E Flaugh
David A Hall
Richard E Heiney
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/800,673 external-priority patent/US4081458A/en
Priority claimed from US05/800,674 external-priority patent/US4082627A/en
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of HU180230B publication Critical patent/HU180230B/hu

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/54—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition of compounds containing doubly bound oxygen atoms, e.g. esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/65—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/72—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
    • C07C45/74—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups combined with dehydration
    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
    • C25B3/00—Electrolytic production of organic compounds
    • C25B3/20—Processes
    • C25B3/25—Reduction

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Reproductive Health (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Hospice & Palliative Care (AREA)
  • Endocrinology (AREA)
  • Electrochemistry (AREA)
  • Materials Engineering (AREA)
  • Metallurgy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pyrane Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

Die Erfindung betrifft ein Verfahren zur Herstellung von Benzopyranoxanthenonen, bei dem ein 2-Hydroxybenzaldehyd mit einem 2,5-Cyclohexadien in Gegenwart von Pyrrolidin oder einer Pyrrolidinverbindung und einer Carbonsäure in einem inerten Lösungsmittel zu einem Dihydrobenzopyranoxanthenon umgesetzt wird.
HU78EI777A 1977-05-26 1978-02-07 Process for producing dihydro- and hexahydrobenzopyranoxantenones HU180230B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/800,673 US4081458A (en) 1977-05-26 1977-05-26 Anti-androgen compounds
US05/800,674 US4082627A (en) 1977-05-26 1977-05-26 Electrolytic reduction of dihydrobenzopyranoxanthenones

Publications (1)

Publication Number Publication Date
HU180230B true HU180230B (en) 1983-02-28

Family

ID=27122240

Family Applications (1)

Application Number Title Priority Date Filing Date
HU78EI777A HU180230B (en) 1977-05-26 1978-02-07 Process for producing dihydro- and hexahydrobenzopyranoxantenones

Country Status (25)

Country Link
JP (1) JPS53147099A (de)
AR (1) AR225133A1 (de)
AT (1) AT361920B (de)
AU (1) AU515424B2 (de)
BG (1) BG30020A3 (de)
CS (1) CS214887B2 (de)
DD (1) DD134766A5 (de)
DE (1) DE2804682A1 (de)
DK (1) DK52978A (de)
ES (1) ES466756A1 (de)
FR (1) FR2392026A1 (de)
GB (1) GB1593643A (de)
GR (1) GR69964B (de)
HU (1) HU180230B (de)
IE (1) IE46392B1 (de)
IL (1) IL53990A (de)
IT (1) IT1092577B (de)
NL (1) NL7801392A (de)
NZ (1) NZ186387A (de)
PL (1) PL110214B1 (de)
PT (1) PT67611B (de)
RO (1) RO74948A (de)
SE (1) SE7801419L (de)
SU (3) SU793395A3 (de)
YU (1) YU26378A (de)

Also Published As

Publication number Publication date
IE780232L (en) 1978-11-26
GR69964B (de) 1982-07-22
GB1593643A (en) 1981-07-22
FR2392026B1 (de) 1980-12-26
PT67611B (en) 1979-07-16
IT7820058A0 (it) 1978-02-07
NZ186387A (en) 1979-06-08
IL53990A (en) 1981-09-13
JPS53147099A (en) 1978-12-21
IE46392B1 (en) 1983-06-01
SU927117A3 (ru) 1982-05-07
PL110214B1 (en) 1980-07-31
IT1092577B (it) 1985-07-12
AR225133A1 (es) 1982-02-26
DE2804682A1 (de) 1978-11-30
PL204508A1 (pl) 1979-01-02
AT361920B (de) 1981-04-10
ATA85178A (de) 1980-09-15
BG30020A3 (en) 1981-03-16
AU3302278A (en) 1979-08-16
ES466756A1 (es) 1979-10-01
PT67611A (en) 1978-03-01
DK52978A (da) 1978-11-27
SU818485A3 (ru) 1981-03-30
FR2392026A1 (fr) 1978-12-22
DD134766A5 (de) 1979-03-21
RO74948A (ro) 1980-10-30
NL7801392A (nl) 1978-11-28
YU26378A (en) 1983-02-28
SE7801419L (sv) 1978-11-27
SU793395A3 (ru) 1980-12-30
CS214887B2 (en) 1982-06-25
AU515424B2 (en) 1981-04-02

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