HU1000565D0 - Process for the preparation of pharmaceutically active compound and intermediers - Google Patents

Process for the preparation of pharmaceutically active compound and intermediers

Info

Publication number
HU1000565D0
HU1000565D0 HU1000565A HUP1000565A HU1000565D0 HU 1000565 D0 HU1000565 D0 HU 1000565D0 HU 1000565 A HU1000565 A HU 1000565A HU P1000565 A HUP1000565 A HU P1000565A HU 1000565 D0 HU1000565 D0 HU 1000565D0
Authority
HU
Hungary
Prior art keywords
intermediers
preparation
active compound
pharmaceutically active
pharmaceutically
Prior art date
Application number
HU1000565A
Other languages
English (en)
Original Assignee
Egis Gyogyszergyar Nyrt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egis Gyogyszergyar Nyrt filed Critical Egis Gyogyszergyar Nyrt
Priority to HU1000565A priority Critical patent/HUP1000565A2/hu
Publication of HU1000565D0 publication Critical patent/HU1000565D0/hu
Priority to PCT/HU2011/000099 priority patent/WO2012052788A1/en
Publication of HUP1000565A2 publication Critical patent/HUP1000565A2/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/02—Systems containing only non-condensed rings with a three-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
HU1000565A 2010-10-22 2010-10-22 Process for the preparation of pharmaceutically active compound and intermediers HUP1000565A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
HU1000565A HUP1000565A2 (en) 2010-10-22 2010-10-22 Process for the preparation of pharmaceutically active compound and intermediers
PCT/HU2011/000099 WO2012052788A1 (en) 2010-10-22 2011-10-21 Method for preparing pharmaceutically active ingredient and intermediates thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU1000565A HUP1000565A2 (en) 2010-10-22 2010-10-22 Process for the preparation of pharmaceutically active compound and intermediers

Publications (2)

Publication Number Publication Date
HU1000565D0 true HU1000565D0 (en) 2010-12-28
HUP1000565A2 HUP1000565A2 (en) 2012-05-02

Family

ID=89990017

Family Applications (1)

Application Number Title Priority Date Filing Date
HU1000565A HUP1000565A2 (en) 2010-10-22 2010-10-22 Process for the preparation of pharmaceutically active compound and intermediers

Country Status (2)

Country Link
HU (1) HUP1000565A2 (hu)
WO (1) WO2012052788A1 (hu)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114216990A (zh) * 2021-12-24 2022-03-22 珠海润都制药股份有限公司 一种溴代三苯甲基四氮唑联苯中二溴海因的检测方法

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU230649B1 (hu) 2013-01-24 2017-05-29 Egis Gyógyszergyár Nyilvánosan Működő Részvénytársaság Javított eljárás prasugrel gyógyszeripari hatóanyag és az 1-ciklopropil-2-(2-fluorofenil)-etanon intermedier előállítására
HU231079B1 (hu) 2016-06-23 2020-06-29 Richter Gedeon Nyrt. Eljárás nagytisztaságú Prasugrel előállítására bromopentil szennyezés eltávolításával
CN112047959A (zh) * 2020-10-21 2020-12-08 深圳市祥根生物科技有限公司 一种普拉格雷开环氯代杂质的制备方法
CN116183772B (zh) * 2023-03-03 2023-09-15 华夏生生药业(北京)有限公司 一种原料药中致突变杂质检测方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI101150B (fi) 1991-09-09 1998-04-30 Sankyo Co Menetelmä lääkeaineina käyttökelpoisten tetrahydrotienopyridiinin johd annaisten valmistamiseksi
US5874581A (en) 1994-10-07 1999-02-23 Ube Industries, Ltd. 2-silyloxy-tetrahydrothienopyridine, salt thereof and process for preparing the same
PT1728794E (pt) 2000-07-06 2008-07-15 Ube Industries Sal de adição maleato de derivados de hidropiridina
KR101784001B1 (ko) 2006-04-04 2017-10-23 케이지 액퀴지션 엘엘씨 항혈소판제와 산 억제제를 포함하는 경구 투여용 약학 조성물
TWI392681B (zh) 2006-04-06 2013-04-11 Daiichi Sankyo Co Ltd 高純度普拉格雷及其酸加成鹽之製法
CN102424686A (zh) 2007-03-02 2012-04-25 第一三共株式会社 用于制备高纯度普拉格雷盐酸盐的方法
CZ302135B6 (cs) 2007-07-09 2010-11-10 Zentiva, A. S. Zpusob výroby 5-[2-cyklopropyl-1-(2-fluorfenyl)-2-oxoethyl]-4, 5, 6, 7-tetrahydrothieno[3,2-c]pyridin-2-yl acetátu (prasugrelu)
US20100261908A1 (en) 2007-11-09 2010-10-14 Dr. Reddy's Laboratories Ltd. Processes for the preparation of prasugrel , and its salts and polymorphs
WO2009066326A2 (en) 2007-11-19 2009-05-28 Msn Laboratories Limited Improved process for the preparation of prasugrel and its pharmaceutically acceptable salts
HU230261B1 (hu) 2007-11-27 2015-11-30 Egis Gyógyszergyár Nyilvánosan Működő Részvénytársaság Eljárás gyógyszeripari intermedierek előállítására
CN101245072B (zh) 2008-03-21 2011-03-30 上海医药工业研究院 制备普拉格雷的中间体及其制备方法
CN101245073B (zh) 2008-03-21 2011-03-23 上海医药工业研究院 一种医药中间体及其制备方法
CN101250192B (zh) 2008-03-24 2010-08-11 上海医药工业研究院 5-(α-环丙基羰基-2-氟苄基)-2-氧-2,4,5,6,7,7a-六氢噻吩并[3,2-c]吡啶的制备方法
CN101250193B (zh) 2008-03-28 2010-09-08 上海医药工业研究院 2-烷氧基-5-(α-环丙基羰基-2-氟苄基)-4,5,6,7-四氢噻吩并[3,2-c]吡啶的制备方法
WO2009122440A1 (en) 2008-03-31 2009-10-08 Torrent Pharmaceuticals Ltd. PROCESS FOR THE PREPARATION OF 2-ACETOXY-5-(α -CYCLOPRPYLCARBONYL -2-FLUOROBENZYL)-4,5,6,7-TETRAHYDROTHIENO[3,2-C]PYRIDINE
CN101531667A (zh) 2009-04-16 2009-09-16 上海立科药物化学有限公司 普拉格雷中间体的合成方法及合成普拉格雷的方法
CN102101827B (zh) * 2010-11-15 2013-07-03 山东新华制药股份有限公司 一种普拉格雷中间体α-环丙羰基-2-氟苄基卤的制备方法

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114216990A (zh) * 2021-12-24 2022-03-22 珠海润都制药股份有限公司 一种溴代三苯甲基四氮唑联苯中二溴海因的检测方法

Also Published As

Publication number Publication date
HUP1000565A2 (en) 2012-05-02
WO2012052788A1 (en) 2012-04-26

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Legal Events

Date Code Title Description
FC4A Lapse of provisional application due to refusal