HRPK20041161B3 - N-benzoylureidocinnamate derivatives, method for production and use thereof - Google Patents

N-benzoylureidocinnamate derivatives, method for production and use thereof

Info

Publication number
HRPK20041161B3
HRPK20041161B3 HR20041161A HRP20041161A HRPK20041161B3 HR PK20041161 B3 HRPK20041161 B3 HR PK20041161B3 HR 20041161 A HR20041161 A HR 20041161A HR P20041161 A HRP20041161 A HR P20041161A HR PK20041161 B3 HRPK20041161 B3 HR PK20041161B3
Authority
HR
Croatia
Prior art keywords
alkyl
alkenyl
coo
alkynyl
cycloalkyl
Prior art date
Application number
HR20041161A
Other languages
English (en)
Croatian (hr)
Inventor
Schoenafinger Karl
Defossa Elisabeth
Kadereit Dieter
Von Roedern Erich
Klabunde Thomas
Burger Hans-Joerg
Herling Andreas
Karl
Original Assignee
Sanofi-Aventis Deutschland Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi-Aventis Deutschland Gmbh filed Critical Sanofi-Aventis Deutschland Gmbh
Publication of HRP20041161A2 publication Critical patent/HRP20041161A2/hr
Publication of HRPK20041161B3 publication Critical patent/HRPK20041161B3/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/46Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylureas
    • C07C275/48Y being a hydrogen or a carbon atom
    • C07C275/54Y being a carbon atom of a six-membered aromatic ring, e.g. benzoylureas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/17Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HR20041161A 2002-06-07 2003-05-22 N-benzoylureidocinnamate derivatives, method for production and use thereof HRPK20041161B3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10225635A DE10225635C1 (de) 2002-06-07 2002-06-07 N-Benzoylureido-Zimtsäurederivate, Verfahren zu deren Herstellung und deren Verwendung
PCT/EP2003/005355 WO2003104188A1 (de) 2002-06-07 2003-05-22 N-benzoylureido-zimtsäurederivate, verfahren zu deren herstellung und deren verwendung

Publications (2)

Publication Number Publication Date
HRP20041161A2 HRP20041161A2 (en) 2005-04-30
HRPK20041161B3 true HRPK20041161B3 (en) 2006-09-30

Family

ID=29594346

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20041161A HRPK20041161B3 (en) 2002-06-07 2003-05-22 N-benzoylureidocinnamate derivatives, method for production and use thereof

Country Status (26)

Country Link
EP (1) EP1513800B1 (enExample)
JP (1) JP4398859B2 (enExample)
KR (1) KR20050004295A (enExample)
CN (1) CN1659137A (enExample)
AT (1) ATE345326T1 (enExample)
AU (1) AU2003238373A1 (enExample)
BR (1) BR0311646A (enExample)
CA (1) CA2488760A1 (enExample)
CY (1) CY1106003T1 (enExample)
DE (2) DE10225635C1 (enExample)
DK (1) DK1513800T3 (enExample)
ES (1) ES2277082T3 (enExample)
HR (1) HRPK20041161B3 (enExample)
IL (1) IL165558A0 (enExample)
IN (1) IN2004CH02747A (enExample)
MA (1) MA27232A1 (enExample)
MX (1) MXPA04011984A (enExample)
NO (1) NO20050087L (enExample)
NZ (1) NZ537004A (enExample)
PL (1) PL372117A1 (enExample)
PT (1) PT1513800E (enExample)
RU (1) RU2004139122A (enExample)
SI (1) SI1513800T1 (enExample)
TW (1) TW200404763A (enExample)
WO (1) WO2003104188A1 (enExample)
ZA (1) ZA200408887B (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7179941B2 (en) 2003-01-23 2007-02-20 Sanofi-Aventis Deutschland Gmbh Carbonylamino-substituted acyl phenyl urea derivatives, process for their preparation and their use
DE10302452B4 (de) * 2003-01-23 2005-02-24 Aventis Pharma Deutschland Gmbh Carbonylamino-substituierte Acyl-phenyl-harnstoffderivate, Verfahren zu deren Herstellung und deren Verwendung
DE10306502B4 (de) * 2003-02-17 2005-03-17 Aventis Pharma Deutschland Gmbh Substituierte 3-(Benzoylureido)-thiophenderivate und sie enthaltende Arzneimittel
DE10308351A1 (de) 2003-02-27 2004-11-25 Aventis Pharma Deutschland Gmbh 1,3-substituierte Cycloalkylderivate mit sauren, meist heterocyclischen Gruppen, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
DE10308352A1 (de) 2003-02-27 2004-09-09 Aventis Pharma Deutschland Gmbh Arylcycloalkylderivate mit verzweigten Seitenketten, Verfahren zu ihrer Herstellung und ihre Anwendung als Arzneimittel
US7148246B2 (en) 2003-02-27 2006-12-12 Sanofi-Aventis Deutschland Gmbh Cycloalkyl derivatives having bioisosteric carboxylic acid groups, processes for their preparation and their use as pharmaceuticals
DE10308355A1 (de) 2003-02-27 2004-12-23 Aventis Pharma Deutschland Gmbh Aryl-cycloalkyl substituierte Alkansäurederivate, Verfahren zu ihrer Herstellung und ihre Anwendung als Arzneimittel
DE10308353A1 (de) 2003-02-27 2004-12-02 Aventis Pharma Deutschland Gmbh Diarylcycloalkylderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
DE10335092B3 (de) * 2003-08-01 2005-02-03 Aventis Pharma Deutschland Gmbh Substituierte Benzoylureido-o-benzoylamide, Verfahren zu deren Herstellung und deren Verwendung
US7241787B2 (en) 2004-01-25 2007-07-10 Sanofi-Aventis Deutschland Gmbh Substituted N-cycloexylimidazolinones, process for their preparation and their use as medicaments
EP1586573B1 (en) 2004-04-01 2007-02-07 Sanofi-Aventis Deutschland GmbH Oxadiazolones, processes for their preparation and their use as pharmaceuticals
US7223786B2 (en) 2004-11-15 2007-05-29 Bristol-Myers Squibb Company 2-aminonaphthalene derivatives and related glycogen phosphorylase inhibitors
US7226942B2 (en) 2004-11-15 2007-06-05 Bristol-Myers Squibb Company 2-amino-4-functionalized tetralin derivatives and related glycogen phosphorylase inhibitors
WO2006053274A2 (en) 2004-11-15 2006-05-18 Bristol-Myers Squibb Company 2-amino-1-functionalized tetralin derivatives and related glycogen phosphorylase inhibitors
US7365061B2 (en) 2004-11-15 2008-04-29 Bristol-Myers Squibb Company 2-Amino-3-functionalized tetralin derivatives and related glycogen phosphorylase inhibitors
DE102005026762A1 (de) 2005-06-09 2006-12-21 Sanofi-Aventis Deutschland Gmbh Azolopyridin-2-on-derivate als Inhibitoren von Lipasen und Phospholipasen
TW200718691A (en) * 2005-06-10 2007-05-16 Sigma Tau Ind Farmaceuti Cinnamic and phenylpropiolic acid derivatives useful as anti-tumour agents
PE20080251A1 (es) 2006-05-04 2008-04-25 Boehringer Ingelheim Int Usos de inhibidores de dpp iv

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL141381B (nl) * 1963-09-25 1974-03-15 Hoechst Ag Werkwijze voor het bereiden van geneesmiddelen met bloedsuikerspiegel verlagende werkzaamheid.
AU601145B2 (en) * 1985-03-01 1990-09-06 Duphar International Research B.V. Benzoyl urea derivatives having anti-tumor activity
ZA867420B (en) * 1985-09-30 1987-05-27 Union Carbide Corp Pesticidal 1-(4-aryloxyphenyl)-3-benzoyl urea compounds and process for preparation
DE4037112A1 (de) * 1990-11-22 1992-05-27 Thomae Gmbh Dr K Neue pyridylderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
GB9313268D0 (en) * 1993-06-28 1993-08-11 Zeneca Ltd Chemical compounds
US6297269B1 (en) * 1995-06-06 2001-10-02 Pfizer Inc. Substituted n-(indole-2-carbonyl-) amides and derivatives as glycogen phosphorylase inhibitors
AR028253A1 (es) * 2000-03-16 2003-04-30 Pfizer Prod Inc Inhibidores de la glucogeno fosforilasa
NZ523034A (en) * 2000-06-09 2004-07-30 Aventis Pharma Gmbh Acylphenyl urea derivatives, methods for the production thereof and use thereof as a medicament
GB0021831D0 (en) * 2000-09-06 2000-10-18 Astrazeneca Ab Chemical compounds

Also Published As

Publication number Publication date
RU2004139122A (ru) 2005-06-10
DK1513800T3 (da) 2007-03-26
ZA200408887B (en) 2005-11-23
MXPA04011984A (es) 2005-03-07
CY1106003T1 (el) 2011-04-06
DE50305693D1 (de) 2006-12-28
KR20050004295A (ko) 2005-01-12
WO2003104188A1 (de) 2003-12-18
SI1513800T1 (sl) 2007-04-30
PT1513800E (pt) 2007-02-28
MA27232A1 (fr) 2005-02-01
NZ537004A (en) 2006-06-30
EP1513800B1 (de) 2006-11-15
IN2004CH02747A (enExample) 2006-02-10
JP4398859B2 (ja) 2010-01-13
TW200404763A (en) 2004-04-01
CA2488760A1 (en) 2003-12-18
CN1659137A (zh) 2005-08-24
IL165558A0 (en) 2006-01-15
NO20050087L (no) 2005-01-06
EP1513800A1 (de) 2005-03-16
DE10225635C1 (de) 2003-12-24
BR0311646A (pt) 2005-03-15
AU2003238373A1 (en) 2003-12-22
ES2277082T3 (es) 2007-07-01
PL372117A1 (en) 2005-07-11
ATE345326T1 (de) 2006-12-15
HRP20041161A2 (en) 2005-04-30
JP2005529164A (ja) 2005-09-29

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Legal Events

Date Code Title Description
A1OB Publication of a patent application
AKOB Publication of a request for the grant of a patent not including a substantive examination of a patent application (a consensual patent)
PNAN Change of the applicant name, address/residence

Owner name: SANOFI-AVENTIS DEUTSCHLAND GMBH, DE

ODRP Renewal fee for the maintenance of a patent

Payment date: 20060412

Year of fee payment: 4

PKB1 Consensual patent granted
PBKO Lapse due to non-payment of renewal fee for consensual patent

Effective date: 20070523