HRP980646B1 - Novel oleandomycin derivatives - Google Patents
Novel oleandomycin derivativesInfo
- Publication number
- HRP980646B1 HRP980646B1 HR980646A HRP980646A HRP980646B1 HR P980646 B1 HRP980646 B1 HR P980646B1 HR 980646 A HR980646 A HR 980646A HR P980646 A HRP980646 A HR P980646A HR P980646 B1 HRP980646 B1 HR P980646B1
- Authority
- HR
- Croatia
- Prior art keywords
- meaning
- group
- individual
- ketone
- hydrogen
- Prior art date
Links
- RZPAKFUAFGMUPI-KGIGTXTPSA-N oleandomycin Chemical class O1[C@@H](C)[C@H](O)[C@@H](OC)C[C@@H]1O[C@@H]1[C@@H](C)C(=O)O[C@H](C)[C@H](C)[C@H](O)[C@@H](C)C(=O)[C@]2(OC2)C[C@H](C)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C RZPAKFUAFGMUPI-KGIGTXTPSA-N 0.000 title 1
- 125000001584 benzyloxycarbonyl group Chemical group C(=O)(OCC1=CC=CC=C1)* 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 150000002576 ketones Chemical class 0.000 abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 235000005985 organic acids Nutrition 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/12—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by acids having the group -X-C(=X)-X-, or halides thereof, in which each X means nitrogen, oxygen, sulfur, selenium or tellurium, e.g. carbonic acid, carbamic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Priority Applications (17)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HR980646A HRP980646B1 (en) | 1998-12-30 | 1998-12-30 | Novel oleandomycin derivatives |
AU30679/00A AU3067900A (en) | 1998-12-30 | 1999-12-29 | Novel derivatives from the class of oleandomycin |
HU0105049A HUP0105049A3 (en) | 1998-12-30 | 1999-12-29 | Novel derivatives from the class of oleandomycin, process for their preparation and their intermediates |
US09/869,606 US6573367B1 (en) | 1998-12-30 | 1999-12-29 | Derivatives from the class of oleandomycin |
PL99349638A PL195977B1 (pl) | 1998-12-30 | 1999-12-29 | Pochodne z klasy oleandomycyny i sposób wytwarzania pochodnych z klasy oleandomycyny |
CA002358594A CA2358594A1 (en) | 1998-12-30 | 1999-12-29 | Novel derivatives from the class of oleandomycin |
ES99964758T ES2280130T3 (es) | 1998-12-30 | 1999-12-29 | Nuevos derivados de la clase de la oleandomicina. |
PCT/HR1999/000035 WO2000040589A2 (en) | 1998-12-30 | 1999-12-29 | Novel derivatives from the class of oleandomycin |
CZ20012316A CZ20012316A3 (cs) | 1998-12-30 | 1999-12-29 | Nové deriváty ze třídy oleandomycinu |
JP2000592297A JP2002534432A (ja) | 1998-12-30 | 1999-12-29 | オレアンドマイシンのクラスからの新規誘導体 |
SK918-2001A SK9182001A3 (en) | 1998-12-30 | 1999-12-29 | Novel derivatives from the class of oleandomycin |
CNB998153036A CN1147500C (zh) | 1998-12-30 | 1999-12-29 | 竹桃霉素类的新衍生物 |
RU2001121147/04A RU2234510C2 (ru) | 1998-12-30 | 1999-12-29 | Производные класса олеандомицина и способ их получения |
EP99964758A EP1140962B1 (de) | 1998-12-30 | 1999-12-29 | Oleandomycin-derivate |
DE69935250T DE69935250T2 (de) | 1998-12-30 | 1999-12-29 | Oleandomycin-derivate |
AT99964758T ATE354580T1 (de) | 1998-12-30 | 1999-12-29 | Oleandomycin-derivate |
HK02103276.7A HK1043597B (zh) | 1998-12-30 | 2002-05-02 | 竹桃霉素類的新衍生物 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HR980646A HRP980646B1 (en) | 1998-12-30 | 1998-12-30 | Novel oleandomycin derivatives |
Publications (2)
Publication Number | Publication Date |
---|---|
HRP980646A2 HRP980646A2 (en) | 2001-02-28 |
HRP980646B1 true HRP980646B1 (en) | 2008-02-29 |
Family
ID=10946862
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HR980646A HRP980646B1 (en) | 1998-12-30 | 1998-12-30 | Novel oleandomycin derivatives |
Country Status (17)
Country | Link |
---|---|
US (1) | US6573367B1 (de) |
EP (1) | EP1140962B1 (de) |
JP (1) | JP2002534432A (de) |
CN (1) | CN1147500C (de) |
AT (1) | ATE354580T1 (de) |
AU (1) | AU3067900A (de) |
CA (1) | CA2358594A1 (de) |
CZ (1) | CZ20012316A3 (de) |
DE (1) | DE69935250T2 (de) |
ES (1) | ES2280130T3 (de) |
HK (1) | HK1043597B (de) |
HR (1) | HRP980646B1 (de) |
HU (1) | HUP0105049A3 (de) |
PL (1) | PL195977B1 (de) |
RU (1) | RU2234510C2 (de) |
SK (1) | SK9182001A3 (de) |
WO (1) | WO2000040589A2 (de) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AR043050A1 (es) | 2002-09-26 | 2005-07-13 | Rib X Pharmaceuticals Inc | Compuestos heterociclicos bifuncionales y metodos para preparar y usar los mismos |
EP2716647A3 (de) | 2004-02-27 | 2014-08-20 | Rib-X Pharmaceuticals, Inc. | Makrocyclische Verbindungen Und Verfahren Zu Deren Herstellung Und Anwendung |
EP1934237A2 (de) | 2005-08-24 | 2008-06-25 | Rib-X Pharmaceuticals, Inc. | Triazolverbindungen und verfahren zu deren herstellung und anwendung |
EP1928893A2 (de) | 2005-08-24 | 2008-06-11 | Rib-X Pharmaceuticals, Inc. | Triazolverbindungen und verfahren zu ihrer herstellung und verwendung |
ATE468119T1 (de) | 2006-06-12 | 2010-06-15 | Univ Ramot | Verfahren zur behandlung von krebs |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2757123A (en) * | 1955-06-29 | 1956-07-31 | Pfizer & Co C | Oleandomycin, its salts and production |
US3144466A (en) * | 1963-03-08 | 1964-08-11 | Pfizer & Co C | Diacyl esters of de-oleandrosehydroxyoleandomycin and process therefor |
LU87039A1 (fr) * | 1987-11-04 | 1989-06-14 | Oreal | Esters biaromatiques d'antibiotiques macrolidiques et lincosamidiques,leur procede de preparation et compositions pharmaceutiques et cosmetiques les contenant |
SI9011409A (en) * | 1990-07-18 | 1995-10-31 | Pliva Pharm & Chem Works | O-methyl azitromycin derivates, methods and intermediates for their preparation and methods for preparation of pharmaceuticals products which comprise them |
RU2052263C1 (ru) * | 1993-10-21 | 1996-01-20 | Товарищество с ограниченной ответственностью "НИТА" | Средство "бентокомплекс" для профилактики и лечения эндометрита у коров |
-
1998
- 1998-12-30 HR HR980646A patent/HRP980646B1/xx not_active IP Right Cessation
-
1999
- 1999-12-29 RU RU2001121147/04A patent/RU2234510C2/ru not_active IP Right Cessation
- 1999-12-29 CZ CZ20012316A patent/CZ20012316A3/cs unknown
- 1999-12-29 CN CNB998153036A patent/CN1147500C/zh not_active Expired - Fee Related
- 1999-12-29 ES ES99964758T patent/ES2280130T3/es not_active Expired - Lifetime
- 1999-12-29 HU HU0105049A patent/HUP0105049A3/hu unknown
- 1999-12-29 US US09/869,606 patent/US6573367B1/en not_active Expired - Fee Related
- 1999-12-29 AT AT99964758T patent/ATE354580T1/de not_active IP Right Cessation
- 1999-12-29 PL PL99349638A patent/PL195977B1/pl unknown
- 1999-12-29 EP EP99964758A patent/EP1140962B1/de not_active Expired - Lifetime
- 1999-12-29 JP JP2000592297A patent/JP2002534432A/ja active Pending
- 1999-12-29 SK SK918-2001A patent/SK9182001A3/sk unknown
- 1999-12-29 DE DE69935250T patent/DE69935250T2/de not_active Expired - Fee Related
- 1999-12-29 CA CA002358594A patent/CA2358594A1/en not_active Abandoned
- 1999-12-29 WO PCT/HR1999/000035 patent/WO2000040589A2/en active IP Right Grant
- 1999-12-29 AU AU30679/00A patent/AU3067900A/en not_active Abandoned
-
2002
- 2002-05-02 HK HK02103276.7A patent/HK1043597B/zh not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
CA2358594A1 (en) | 2000-07-13 |
CN1332746A (zh) | 2002-01-23 |
HK1043597A1 (en) | 2002-09-20 |
HUP0105049A3 (en) | 2003-10-28 |
ATE354580T1 (de) | 2007-03-15 |
EP1140962B1 (de) | 2007-02-21 |
PL195977B1 (pl) | 2007-11-30 |
EP1140962A2 (de) | 2001-10-10 |
WO2000040589A3 (en) | 2000-11-23 |
HRP980646A2 (en) | 2001-02-28 |
HK1043597B (zh) | 2004-10-08 |
AU3067900A (en) | 2000-07-24 |
JP2002534432A (ja) | 2002-10-15 |
ES2280130T3 (es) | 2007-09-01 |
RU2234510C2 (ru) | 2004-08-20 |
SK9182001A3 (en) | 2002-01-07 |
CN1147500C (zh) | 2004-04-28 |
US6573367B1 (en) | 2003-06-03 |
WO2000040589A2 (en) | 2000-07-13 |
DE69935250D1 (de) | 2007-04-05 |
CZ20012316A3 (cs) | 2001-10-17 |
DE69935250T2 (de) | 2007-10-31 |
HUP0105049A2 (hu) | 2002-04-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
A1OB | Publication of a patent application | ||
AIPI | Request for the grant of a patent on the basis of a substantive examination of a patent application | ||
PPPP | Transfer of rights |
Owner name: PLIVA-ISTRAZIVACKI INSTITUT D.O.O., HR |
|
PNAN | Change of the applicant name, address/residence |
Owner name: GLAXOSMITHKLINE ISTRAZIVACKI CENTAR ZAGREB D.O.O., |
|
ODRP | Renewal fee for the maintenance of a patent |
Payment date: 20080206 Year of fee payment: 9 |
|
B1PR | Patent granted | ||
PBON | Lapse due to non-payment of renewal fee |
Effective date: 20081231 |