HUP0105049A2 - Az oleandomicinek osztályába tartozó új származékok, eljárás az előállításukra és az intermedierjeik - Google Patents

Az oleandomicinek osztályába tartozó új származékok, eljárás az előállításukra és az intermedierjeik

Info

Publication number
HUP0105049A2
HUP0105049A2 HU0105049A HUP0105049A HUP0105049A2 HU P0105049 A2 HUP0105049 A2 HU P0105049A2 HU 0105049 A HU0105049 A HU 0105049A HU P0105049 A HUP0105049 A HU P0105049A HU P0105049 A2 HUP0105049 A2 HU P0105049A2
Authority
HU
Hungary
Prior art keywords
formula
group
class
oleandomycin
intermediates
Prior art date
Application number
HU0105049A
Other languages
English (en)
Inventor
Gordana Burek
Gabrijela Kobrehel
Gorjana Lazarevski
Original Assignee
Pliva, Farmaceutska Industrija, Dionicko Drustvo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pliva, Farmaceutska Industrija, Dionicko Drustvo filed Critical Pliva, Farmaceutska Industrija, Dionicko Drustvo
Publication of HUP0105049A2 publication Critical patent/HUP0105049A2/hu
Publication of HUP0105049A3 publication Critical patent/HUP0105049A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/12—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by acids having the group -X-C(=X)-X-, or halides thereof, in which each X means nitrogen, oxygen, sulfur, selenium or tellurium, e.g. carbonic acid, carbamic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

A tal lm ny t rgya a makrolid antibiotikus-oleandomicinek oszt ly batartozó (I) ltal nos képletű új vegyületek és szervetlen vagy szervessavakkal képezett, gyógy szatilag elfogadható addíciós sóik - ahol R1jelentése -CH2CH3 csoport, (II) képletű csoport, R1 és R2 együtt (III)képletű csoportot képez, vagy R1 és R4 együttes jelentése (IV) vagy(V) képletű csoport. A tal lm ny kiterjed a vegyületek elő llít s raés az elő llít sra szolg ló intermedierekre is. Ó
HU0105049A 1998-12-30 1999-12-29 Novel derivatives from the class of oleandomycin, process for their preparation and their intermediates HUP0105049A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HR980646A HRP980646B1 (en) 1998-12-30 1998-12-30 Novel oleandomycin derivatives
PCT/HR1999/000035 WO2000040589A2 (en) 1998-12-30 1999-12-29 Novel derivatives from the class of oleandomycin

Publications (2)

Publication Number Publication Date
HUP0105049A2 true HUP0105049A2 (hu) 2002-04-29
HUP0105049A3 HUP0105049A3 (en) 2003-10-28

Family

ID=10946862

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0105049A HUP0105049A3 (en) 1998-12-30 1999-12-29 Novel derivatives from the class of oleandomycin, process for their preparation and their intermediates

Country Status (17)

Country Link
US (1) US6573367B1 (hu)
EP (1) EP1140962B1 (hu)
JP (1) JP2002534432A (hu)
CN (1) CN1147500C (hu)
AT (1) ATE354580T1 (hu)
AU (1) AU3067900A (hu)
CA (1) CA2358594A1 (hu)
CZ (1) CZ20012316A3 (hu)
DE (1) DE69935250T2 (hu)
ES (1) ES2280130T3 (hu)
HK (1) HK1043597B (hu)
HR (1) HRP980646B1 (hu)
HU (1) HUP0105049A3 (hu)
PL (1) PL195977B1 (hu)
RU (1) RU2234510C2 (hu)
SK (1) SK9182001A3 (hu)
WO (1) WO2000040589A2 (hu)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200420573A (en) 2002-09-26 2004-10-16 Rib X Pharmaceuticals Inc Bifunctional heterocyclic compounds and methods of making and using same
JP5383037B2 (ja) * 2004-02-27 2014-01-08 リブ−エックス ファーマシューティカルズ，インコーポレイテッド 大環状化合物およびそれらを製造し使用する方法
US8470985B2 (en) 2005-08-24 2013-06-25 Rib-X Pharmaceuticals, Inc. Triazole compounds and methods of making and using the same
US8278281B2 (en) 2005-08-24 2012-10-02 Rib-X Pharmaceuticals, Inc. Triazole compounds and methods of making and using the same
ATE468119T1 (de) 2006-06-12 2010-06-15 Univ Ramot Verfahren zur behandlung von krebs

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2757123A (en) * 1955-06-29 1956-07-31 Pfizer & Co C Oleandomycin, its salts and production
US3144466A (en) * 1963-03-08 1964-08-11 Pfizer & Co C Diacyl esters of de-oleandrosehydroxyoleandomycin and process therefor
LU87039A1 (fr) * 1987-11-04 1989-06-14 Oreal Esters biaromatiques d'antibiotiques macrolidiques et lincosamidiques,leur procede de preparation et compositions pharmaceutiques et cosmetiques les contenant
SI9011409A (en) * 1990-07-18 1995-10-31 Pliva Pharm & Chem Works O-methyl azitromycin derivates, methods and intermediates for their preparation and methods for preparation of pharmaceuticals products which comprise them
RU2052263C1 (ru) * 1993-10-21 1996-01-20 Товарищество с ограниченной ответственностью "НИТА" Средство "бентокомплекс" для профилактики и лечения эндометрита у коров

Also Published As

Publication number Publication date
WO2000040589A3 (en) 2000-11-23
DE69935250D1 (de) 2007-04-05
JP2002534432A (ja) 2002-10-15
HRP980646B1 (en) 2008-02-29
US6573367B1 (en) 2003-06-03
CN1332746A (zh) 2002-01-23
EP1140962B1 (en) 2007-02-21
HRP980646A2 (en) 2001-02-28
CZ20012316A3 (cs) 2001-10-17
DE69935250T2 (de) 2007-10-31
CN1147500C (zh) 2004-04-28
SK9182001A3 (en) 2002-01-07
HK1043597A1 (en) 2002-09-20
ES2280130T3 (es) 2007-09-01
PL195977B1 (pl) 2007-11-30
HK1043597B (zh) 2004-10-08
RU2234510C2 (ru) 2004-08-20
EP1140962A2 (en) 2001-10-10
ATE354580T1 (de) 2007-03-15
CA2358594A1 (en) 2000-07-13
HUP0105049A3 (en) 2003-10-28
WO2000040589A2 (en) 2000-07-13
AU3067900A (en) 2000-07-24

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Legal Events

Date Code Title Description
FD9A Lapse of provisional protection due to non-payment of fees