HRP980169B1 - Ortho-substituted benzoylguanidines, process for their preparation, their use as medicament or diagnostic agent as well as medicaments containing them - Google Patents

Ortho-substituted benzoylguanidines, process for their preparation, their use as medicament or diagnostic agent as well as medicaments containing them

Info

Publication number
HRP980169B1
HRP980169B1 HR980169A HRP980169A HRP980169B1 HR P980169 B1 HRP980169 B1 HR P980169B1 HR 980169 A HR980169 A HR 980169A HR P980169 A HRP980169 A HR P980169A HR P980169 B1 HRP980169 B1 HR P980169B1
Authority
HR
Croatia
Prior art keywords
ortho
medicament
preparation
well
diagnostic agent
Prior art date
Application number
HR980169A
Other languages
English (en)
Inventor
Andreas Weichert
Joachim Brendel
Heinz-Werner Kleemann
Jans Jochen Lang
Jan-Robert Schwark
Udo Albus
Wolfgang Scholz
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of HRP980169A2 publication Critical patent/HRP980169A2/hr
Publication of HRP980169B1 publication Critical patent/HRP980169B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/22—Y being a hydrogen or a carbon atom, e.g. benzoylguanidines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Biomedical Technology (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pulmonology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HR980169A 1997-04-01 1998-03-31 Ortho-substituted benzoylguanidines, process for their preparation, their use as medicament or diagnostic agent as well as medicaments containing them HRP980169B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19713427A DE19713427A1 (de) 1997-04-01 1997-04-01 Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament

Publications (2)

Publication Number Publication Date
HRP980169A2 HRP980169A2 (en) 1998-12-31
HRP980169B1 true HRP980169B1 (en) 2002-06-30

Family

ID=7825126

Family Applications (1)

Application Number Title Priority Date Filing Date
HR980169A HRP980169B1 (en) 1997-04-01 1998-03-31 Ortho-substituted benzoylguanidines, process for their preparation, their use as medicament or diagnostic agent as well as medicaments containing them

Country Status (29)

Country Link
US (1) US6075054A (no)
EP (1) EP0869116B1 (no)
JP (1) JP4160650B2 (no)
KR (1) KR19980080899A (no)
CN (1) CN1097579C (no)
AR (1) AR011207A1 (no)
AT (1) ATE210636T1 (no)
AU (1) AU729230B2 (no)
BR (1) BR9800989A (no)
CA (1) CA2232461A1 (no)
CZ (1) CZ290041B6 (no)
DE (2) DE19713427A1 (no)
DK (1) DK0869116T3 (no)
ES (1) ES2169453T3 (no)
HR (1) HRP980169B1 (no)
HU (1) HUP9800745A3 (no)
ID (1) ID19397A (no)
IL (1) IL123874A (no)
MY (1) MY117500A (no)
NO (1) NO309033B1 (no)
NZ (1) NZ330076A (no)
PL (1) PL189605B1 (no)
PT (1) PT869116E (no)
RU (1) RU2227796C2 (no)
SI (1) SI0869116T1 (no)
SK (1) SK282350B6 (no)
TR (1) TR199800577A2 (no)
TW (1) TW574192B (no)
ZA (1) ZA982688B (no)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19951702A1 (de) * 1999-10-27 2001-05-03 Aventis Pharma Gmbh Verwendung von 2-Amino-3,4-dihydro-chinazolinen zur Herstellung eines Medikaments zur Behandlung oder Prophylaxe von durch ischämischen Zuständen bewirkten Krankheiten
OA13285A (en) * 2003-11-13 2007-01-31 Sanofi Aventis Deutschland Pentafluorosulfanyl benzoylguanidines, method for their production, their use as medicaments or diagnostic agents and medicament containing the same.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4328869A1 (de) * 1993-08-27 1995-03-02 Hoechst Ag Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE4430212A1 (de) * 1994-08-28 1996-02-29 Merck Patent Gmbh Ortho-substituierte Benzoesäure-Derivate
DE19517848A1 (de) * 1995-05-16 1996-11-21 Merck Patent Gmbh Fluorhaltige Benzoylguanidine
DE19606509A1 (de) * 1996-02-22 1997-08-28 Hoechst Ag Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE19624178A1 (de) * 1996-06-18 1998-01-08 Hoechst Ag Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament

Also Published As

Publication number Publication date
CZ290041B6 (cs) 2002-05-15
SK41698A3 (en) 1999-04-13
AU5972298A (en) 1998-10-08
TR199800577A2 (xx) 1998-10-21
ATE210636T1 (de) 2001-12-15
CZ97698A3 (cs) 1998-11-11
JPH10298157A (ja) 1998-11-10
PT869116E (pt) 2002-06-28
IL123874A (en) 2003-11-23
CA2232461A1 (en) 1998-10-01
AU729230B2 (en) 2001-01-25
HUP9800745A2 (hu) 1998-12-28
HRP980169A2 (en) 1998-12-31
DE19713427A1 (de) 1998-10-08
TW574192B (en) 2004-02-01
SK282350B6 (sk) 2002-01-07
NO981446D0 (no) 1998-03-31
HUP9800745A3 (en) 2000-03-28
CN1097579C (zh) 2003-01-01
EP0869116B1 (de) 2001-12-12
NZ330076A (en) 1999-08-30
NO309033B1 (no) 2000-12-04
AR011207A1 (es) 2000-08-02
SI0869116T1 (en) 2002-06-30
JP4160650B2 (ja) 2008-10-01
KR19980080899A (ko) 1998-11-25
DK0869116T3 (da) 2002-04-08
PL325670A1 (en) 1998-10-12
IL123874A0 (en) 1998-10-30
ES2169453T3 (es) 2002-07-01
MY117500A (en) 2004-07-31
EP0869116A1 (de) 1998-10-07
DE59802390D1 (de) 2002-01-24
CN1194976A (zh) 1998-10-07
US6075054A (en) 2000-06-13
PL189605B1 (pl) 2005-08-31
BR9800989A (pt) 2000-02-29
NO981446L (no) 1998-10-02
ID19397A (id) 1998-07-09
RU2227796C2 (ru) 2004-04-27
ZA982688B (en) 1998-10-01

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Legal Events

Date Code Title Description
A1OB Publication of a patent application
AIPI Request for the grant of a patent on the basis of a substantive examination of a patent application
B1PR Patent granted
ODRP Renewal fee for the maintenance of a patent

Payment date: 20050215

Year of fee payment: 8

PBON Lapse due to non-payment of renewal fee

Effective date: 20060401