HRP940978B1 - Long-acting injection suspensions and a process for their preparation - Google Patents

Long-acting injection suspensions and a process for their preparation

Info

Publication number
HRP940978B1
HRP940978B1 HR940978A HRP940978A HRP940978B1 HR P940978 B1 HRP940978 B1 HR P940978B1 HR 940978 A HR940978 A HR 940978A HR P940978 A HRP940978 A HR P940978A HR P940978 B1 HRP940978 B1 HR P940978B1
Authority
HR
Croatia
Prior art keywords
preparation
long
injection suspensions
acting injection
acting
Prior art date
Application number
HR940978A
Other languages
English (en)
Croatian (hr)
Inventor
Engel J�rgen
Klokkers-Bethke Karin
Reissmann Thomas
Hilgard Peter
Original Assignee
Zentaris Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zentaris Gmbh filed Critical Zentaris Gmbh
Priority claimed from US08/661,017 external-priority patent/US5773032A/en
Publication of HRP940978A2 publication Critical patent/HRP940978A2/xx
Publication of HRP940978B1 publication Critical patent/HRP940978B1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A61K38/105—Bombesin; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HR940978A 1993-12-09 1994-12-08 Long-acting injection suspensions and a process for their preparation HRP940978B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4342092A DE4342092B4 (de) 1993-12-09 1993-12-09 Langwirkende Injektionssuspension und Verfahren zur Herstellung
US08/661,017 US5773032A (en) 1993-12-09 1996-06-10 Long-acting injection suspensions and a process for their preparation

Publications (2)

Publication Number Publication Date
HRP940978A2 HRP940978A2 (en) 1997-02-28
HRP940978B1 true HRP940978B1 (en) 2006-08-31

Family

ID=25931926

Family Applications (1)

Application Number Title Priority Date Filing Date
HR940978A HRP940978B1 (en) 1993-12-09 1994-12-08 Long-acting injection suspensions and a process for their preparation

Country Status (27)

Country Link
EP (1) EP0732934B1 (sh)
JP (1) JPH09509145A (sh)
CN (2) CN1248732C (sh)
AT (1) ATE310530T1 (sh)
AU (1) AU677748B2 (sh)
BR (1) BR9408272A (sh)
CZ (1) CZ291025B6 (sh)
DE (1) DE4342092B4 (sh)
DK (1) DK0732934T3 (sh)
EE (1) EE03224B1 (sh)
EG (1) EG20787A (sh)
ES (1) ES2251715T3 (sh)
FI (1) FI116121B (sh)
HK (1) HK1063746A1 (sh)
HR (1) HRP940978B1 (sh)
HU (1) HU217081B (sh)
IL (1) IL111928A (sh)
LV (1) LV11596B (sh)
NO (1) NO318984B1 (sh)
NZ (1) NZ277239A (sh)
PL (1) PL186929B1 (sh)
RO (1) RO119343B1 (sh)
RS (1) RS49511B (sh)
RU (1) RU2152222C1 (sh)
SK (2) SK284981B6 (sh)
WO (1) WO1995015767A1 (sh)
ZA (1) ZA949798B (sh)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6828415B2 (en) * 1993-02-19 2004-12-07 Zentaris Gmbh Oligopeptide lyophilisate, their preparation and use
UA44722C2 (uk) * 1993-12-09 2002-03-15 Аста Медіка Акціенгезельшафт Лікарський засіб пролонгованої дії для зниження рівня тестостерону
AU5678398A (en) * 1997-01-29 1998-08-18 Takeda Chemical Industries Ltd. Sustained-release microspheres, their production and use
DE10040700A1 (de) * 2000-08-17 2002-02-28 Asta Medica Ag Salze von biologisch aktiven Peptiden, ihre Herstellung und Verwendung
AU2002221139A1 (en) * 2000-12-15 2002-06-24 Takeda Chemical Industries Ltd. Medicinal compositions of nonpeptidyl gonadotropin-releasing hormone agonist or antagonist, process for producing the same and use thereof
TWI332407B (en) 2001-06-29 2010-11-01 Takeda Chemical Industries Ltd Controlled release composition and method of producting the same
US7098305B2 (en) 2001-09-06 2006-08-29 Ardana Bioscience Limited Sustained release of microcrystalline peptide suspensions
EP1674082A1 (de) 2004-12-22 2006-06-28 Zentaris GmbH Verfahren zur Herstellung von sterilen Suspensionen oder Lyophilisaten schwerlöslicher basischer Peptidkomplexe, diese enthaltende pharmazeutische Formulierungen sowie ihre Verwendung als Arzneimittel
CN101563068B (zh) 2006-12-18 2013-03-20 武田药品工业株式会社 缓释组合物和其制备方法
RU2548753C2 (ru) 2009-11-16 2015-04-20 Ипсен Фарма С.А.С. Фармацевтические композиции лигандов рецепторов меланокортинов
CN102504018A (zh) * 2011-10-28 2012-06-20 沈阳药科大学 可持续释放的蜂毒肽帕莫酸盐及其制剂
WO2017167180A1 (zh) * 2016-03-29 2017-10-05 上海华汇拓医药科技有限公司 沃替西汀的帕莫酸盐及其晶型
CN108969478A (zh) * 2018-08-29 2018-12-11 江南大学 一种美金刚难溶盐缓释注射剂及其制备方法
CN110003195B (zh) * 2019-05-21 2020-05-26 湖北中医药大学 鲁拉西酮晶体及其制备方法和在注射给药系统中的应用
CN112569340A (zh) * 2020-12-31 2021-03-30 苏州素仕生物科技有限公司 一种无菌布舍瑞林注射液及其制备方法和应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3852422A (en) * 1971-06-26 1974-12-03 Serono Ist Farm Long-active gonadotropins
NZ181036A (en) * 1975-06-12 1978-12-18 A Schally Luteinising hormone releasing hormone analogues and intermediates therefor
GB2209937B (en) * 1987-09-21 1991-07-03 Depiopharm S A Water insoluble polypeptides
FR2647677B1 (fr) * 1989-05-31 1991-09-27 Roussel Uclaf Nouvelles micro-proteines, procede de preparation et application a titre de medicaments de ces nouvelles micro-proteines
CH679207A5 (sh) * 1989-07-28 1992-01-15 Debiopharm Sa
CH683149A5 (fr) * 1991-07-22 1994-01-31 Debio Rech Pharma Sa Procédé pour la préparation de microsphères en matériau polymère biodégradable.

Also Published As

Publication number Publication date
PL186929B1 (pl) 2004-04-30
DE4342092B4 (de) 2007-01-11
EP0732934A1 (en) 1996-09-25
EG20787A (en) 2000-02-29
SK284980B6 (sk) 2006-03-02
CN1136916C (zh) 2004-02-04
WO1995015767A1 (en) 1995-06-15
ES2251715T3 (es) 2006-05-01
NO961877L (no) 1996-05-09
CZ142096A3 (en) 1996-12-11
DE4342092A1 (de) 1995-06-14
DK0732934T3 (da) 2006-03-27
NZ277239A (en) 1997-03-24
RS49511B (sr) 2006-10-27
LV11596A (lv) 1996-12-20
HU9601584D0 (en) 1996-08-28
RO119343B1 (ro) 2004-08-30
JPH09509145A (ja) 1997-09-16
AU1219995A (en) 1995-06-27
FI116121B (fi) 2005-09-30
AU677748B2 (en) 1997-05-01
HU217081B (hu) 1999-11-29
IL111928A (en) 1999-11-30
CN1494919A (zh) 2004-05-12
NO961877D0 (no) 1996-05-09
NO318984B1 (no) 2005-05-30
CN1136779A (zh) 1996-11-27
SK284981B6 (sk) 2006-03-02
CN1248732C (zh) 2006-04-05
ZA949798B (en) 1995-08-18
FI962354A0 (fi) 1996-06-06
SK66796A3 (en) 1997-08-06
EE03224B1 (et) 1999-10-15
EP0732934B1 (en) 2005-11-23
RU2152222C1 (ru) 2000-07-10
HRP940978A2 (en) 1997-02-28
CZ291025B6 (cs) 2002-12-11
YU72194A (sh) 1997-03-07
IL111928A0 (en) 1995-03-15
PL314913A1 (en) 1996-09-30
BR9408272A (pt) 1996-12-17
ATE310530T1 (de) 2005-12-15
HK1063746A1 (en) 2005-01-14
HUT75712A (en) 1997-05-28
LV11596B (en) 1997-06-20
FI962354A (fi) 1996-06-06

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Legal Events

Date Code Title Description
A1OB Publication of a patent application
AIPI Request for the grant of a patent on the basis of a substantive examination of a patent application
PPPP Transfer of rights

Owner name: ZENTARIS AG, DE

PNAN Change of the applicant name, address/residence

Owner name: ZENTARIS GMBH, DE

PNAN Change of the applicant name, address/residence

Owner name: ZENTARIS GMBH, DE

B1PR Patent granted
ODRP Renewal fee for the maintenance of a patent

Payment date: 20091204

Year of fee payment: 16

PBON Lapse due to non-payment of renewal fee

Effective date: 20101209