HRP921250B1 - Process for the preparation of new pharmacologically active catechol derivatives - Google Patents

Process for the preparation of new pharmacologically active catechol derivatives

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Publication number
HRP921250B1
HRP921250B1 HR921250A HRP921250A HRP921250B1 HR P921250 B1 HRP921250 B1 HR P921250B1 HR 921250 A HR921250 A HR 921250A HR P921250 A HRP921250 A HR P921250A HR P921250 B1 HRP921250 B1 HR P921250B1
Authority
HR
Croatia
Prior art keywords
preparation
pharmacologically active
catechol derivatives
new pharmacologically
active catechol
Prior art date
Application number
HR921250A
Other languages
English (en)
Inventor
Reijo Johannes Backstrom
Kalevi Evert Heinola
Erkki Juhani Honkanen
Seppo Kelavi Kaakkola
Pekka Juhani Kairisalo
Inge-Britt Yvonne Linden
Pekka Topias Mannisto
Erkki Aarne Olavi Nissinen
Pentti Pohto
Aino Kyllikki Pippuri
Jarmo Johan Pystynen
Original Assignee
Orion Yhtymae Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from YU2189A external-priority patent/YU48020B/sh
Application filed by Orion Yhtymae Oy filed Critical Orion Yhtymae Oy
Publication of HRP921250A2 publication Critical patent/HRP921250A2/xx
Publication of HRP921250B1 publication Critical patent/HRP921250B1/xx

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    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/333—Radicals substituted by oxygen or sulfur atoms
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C07C205/21—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by hydroxy groups having nitro groups and hydroxy groups bound to carbon atoms of six-membered aromatic rings having nitro groups and hydroxy groups bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C205/22—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by hydroxy groups having nitro groups and hydroxy groups bound to carbon atoms of six-membered aromatic rings having nitro groups and hydroxy groups bound to carbon atoms of the same non-condensed six-membered aromatic ring having one nitro groups bound to the ring
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    • C07C205/21—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by hydroxy groups having nitro groups and hydroxy groups bound to carbon atoms of six-membered aromatic rings having nitro groups and hydroxy groups bound to carbon atoms of the same non-condensed six-membered aromatic ring
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    • C07C205/37—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton to carbon atoms of the same non-condensed six-membered aromatic ring or to carbon atoms of six-membered aromatic rings being part of the same condensed ring system the oxygen atom of at least one of the etherified hydroxy groups being further bound to an acyclic carbon atom
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    • C07C45/562—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with nitrogen as the only hetero atom
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    • C07C45/74—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups combined with dehydration
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    • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
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    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
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    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
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HR921250A 1986-11-28 1992-11-12 Process for the preparation of new pharmacologically active catechol derivatives HRP921250B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FI864875A FI864875A0 (fi) 1986-11-28 1986-11-28 Nya farmakologiskt aktiva foereningar, dessa innehaollande kompositioner samt foerfarande och mellanprodukter foer anvaendning vid framstaellning av dessa.
GB878712437A GB8712437D0 (en) 1986-11-28 1987-05-27 Pharmacologically active compounds
YU2189A YU48020B (sh) 1986-11-28 1989-01-06 Postupak za dobijanje novih farmakoloških aktivnih ketholnih derivata

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HRP921250A2 HRP921250A2 (en) 1998-06-30
HRP921250B1 true HRP921250B1 (en) 2000-06-30

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KR (1) KR960004771B1 (sv)
DD (1) DD281375A5 (sv)
FI (2) FI864875A0 (sv)
GB (1) GB8712437D0 (sv)
HR (1) HRP921250B1 (sv)
LT (1) LT3770B (sv)
MX (1) MX9524A (sv)
NO (1) NO1999010I1 (sv)
PL (1) PL154006B1 (sv)
SU (1) SU1729291A3 (sv)
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US8334305B2 (en) * 2007-02-23 2012-12-18 High Point Pharmaceuticals, Llc N-adamantyl benzamides as inhibitors of 11-β-hydroxysteroid dehydrogenase
JP2010519240A (ja) * 2007-02-23 2010-06-03 ハイ ポイント ファーマシューティカルズ，リミティド ライアビリティ カンパニー １１−ベータ−ヒドロキシステロイドデヒドロゲナーゼの阻害剤としての、ｎ−アダマンチルベンズアミド
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DD281375A5 (de) 1990-08-08
KR960004771B1 (en) 1996-04-13
FI875229A (sv) 1988-05-29
FI93350B (sv) 1994-12-15
PL154006B1 (en) 1991-06-28
SU1729291A3 (ru) 1992-04-23
MX9524A (es) 1993-12-01
FI93350C (sv) 1995-03-27
NO1999010I1 (no) 1999-06-10
KR880006170A (ko) 1988-07-21
GB8712437D0 (en) 1987-07-01
HRP921250A2 (en) 1998-06-30
ZA878953B (en) 1988-05-24
US5112861A (en) 1992-05-12
FI875229A0 (sv) 1987-11-27
FI864875A0 (fi) 1986-11-28
LT3770B (en) 1996-03-25
LTIP915A (en) 1995-03-27

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