HRP20220557T1 - Spoj obilježen s 18f namijenjen dijagnosticiranju raka, te njegova upotreba - Google Patents
Spoj obilježen s 18f namijenjen dijagnosticiranju raka, te njegova upotreba Download PDFInfo
- Publication number
- HRP20220557T1 HRP20220557T1 HRP20220557TT HRP20220557T HRP20220557T1 HR P20220557 T1 HRP20220557 T1 HR P20220557T1 HR P20220557T T HRP20220557T T HR P20220557TT HR P20220557 T HRP20220557 T HR P20220557T HR P20220557 T1 HRP20220557 T1 HR P20220557T1
- Authority
- HR
- Croatia
- Prior art keywords
- prostate cancer
- fact
- indicated
- diagnosis
- compound according
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title claims 6
- 238000003745 diagnosis Methods 0.000 title claims 4
- 206010060862 Prostate cancer Diseases 0.000 title claims 3
- 208000000236 Prostatic Neoplasms Diseases 0.000 title claims 3
- -1 (pyridin-4-yl)methyl Chemical group 0.000 claims 4
- 239000004480 active ingredient Substances 0.000 claims 2
- 229910052739 hydrogen Inorganic materials 0.000 claims 2
- 239000001257 hydrogen Substances 0.000 claims 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 2
- 239000012217 radiopharmaceutical Substances 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 238000002595 magnetic resonance imaging Methods 0.000 claims 1
- 239000000825 pharmaceutical preparation Substances 0.000 claims 1
- 238000002600 positron emission tomography Methods 0.000 claims 1
- 229940121896 radiopharmaceutical Drugs 0.000 claims 1
- 230000002799 radiopharmaceutical effect Effects 0.000 claims 1
- 230000000007 visual effect Effects 0.000 claims 1
- 238000012800 visualization Methods 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0402—Organic compounds carboxylic acid carriers, fatty acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/085—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0453—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0497—Organic compounds conjugates with a carrier being an organic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Radiology & Medical Imaging (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nuclear Medicine (AREA)
- Plural Heterocyclic Compounds (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR20170077570 | 2017-06-19 | ||
| PCT/KR2018/006869 WO2018236115A1 (ko) | 2017-06-19 | 2018-06-18 | 전립선암 진단을 위한 18f-표지된 화합물 및 그의 용도 |
| EP18820848.2A EP3643707B1 (en) | 2017-06-19 | 2018-06-18 | 18f-labelled compound for prostate cancer diagnosis, and use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20220557T1 true HRP20220557T1 (hr) | 2022-06-10 |
Family
ID=65008286
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20220557TT HRP20220557T1 (hr) | 2017-06-19 | 2018-06-18 | Spoj obilježen s 18f namijenjen dijagnosticiranju raka, te njegova upotreba |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US10870629B2 (https=) |
| EP (1) | EP3643707B1 (https=) |
| JP (1) | JP6913968B2 (https=) |
| KR (1) | KR102015355B1 (https=) |
| CN (1) | CN110770212B (https=) |
| AU (1) | AU2018288907B2 (https=) |
| CA (1) | CA3067696C (https=) |
| CL (1) | CL2019003727A1 (https=) |
| DK (1) | DK3643707T3 (https=) |
| EA (1) | EA037781B1 (https=) |
| ES (1) | ES2912392T3 (https=) |
| HR (1) | HRP20220557T1 (https=) |
| LT (1) | LT3643707T (https=) |
| MX (1) | MX388833B (https=) |
| MY (1) | MY195426A (https=) |
| PH (1) | PH12019502665A1 (https=) |
| PL (1) | PL3643707T3 (https=) |
| PT (1) | PT3643707T (https=) |
| RS (1) | RS63205B1 (https=) |
| SG (1) | SG11201911602RA (https=) |
| SI (1) | SI3643707T1 (https=) |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2494096C2 (ru) | 2008-08-01 | 2013-09-27 | Дзе Джонс Хопкинс Юниверсити | Агенты, связывающиеся с psma, и их применение |
| WO2013022797A1 (en) * | 2011-08-05 | 2013-02-14 | Molecular Insight Pharmaceuticals | Radiolabeled prostate specific membrane antigen inhibitors |
| WO2013028664A1 (en) | 2011-08-22 | 2013-02-28 | Siemens Medical Solutions Usa, Inc. | Psma imaging agents |
| JP2014051442A (ja) * | 2012-09-05 | 2014-03-20 | Kyoto Univ | 前立腺がんを診断可能な核医学イメージングプローブ |
| EP3300746B1 (en) * | 2013-01-14 | 2019-05-15 | Molecular Insight Pharmaceuticals, Inc. | Triazine based radiopharmaceuticals and radioimaging agents |
| ES3005832T3 (en) | 2013-11-13 | 2025-03-17 | Ge Healthcare Ltd | Dual run cassette for the synthesis of 18f-labelled compounds |
| KR20150113801A (ko) * | 2014-03-31 | 2015-10-08 | 한미약품 주식회사 | Tak1 저해 활성을 갖는 피라진 접합고리 유도체 |
| FR3023290B1 (fr) * | 2014-07-04 | 2016-08-19 | Pf Medicament | Derives de flavaglines |
| WO2017027870A1 (en) * | 2015-08-13 | 2017-02-16 | The Johns Hopkins University | Triazole conjugated ureas, thioureas, carbamates, and "reversed" carbamates for psma-targeted imaging agents and uses thereof |
| EP3493856B1 (en) | 2016-06-28 | 2023-08-09 | Cornell University | 18f-labeled triazole containing psma inhibitors |
-
2018
- 2018-06-18 EP EP18820848.2A patent/EP3643707B1/en active Active
- 2018-06-18 LT LTEPPCT/KR2018/006869T patent/LT3643707T/lt unknown
- 2018-06-18 CA CA3067696A patent/CA3067696C/en active Active
- 2018-06-18 MY MYPI2019007226A patent/MY195426A/en unknown
- 2018-06-18 HR HRP20220557TT patent/HRP20220557T1/hr unknown
- 2018-06-18 RS RS20220436A patent/RS63205B1/sr unknown
- 2018-06-18 DK DK18820848.2T patent/DK3643707T3/da active
- 2018-06-18 JP JP2019571446A patent/JP6913968B2/ja active Active
- 2018-06-18 AU AU2018288907A patent/AU2018288907B2/en active Active
- 2018-06-18 SI SI201830663T patent/SI3643707T1/sl unknown
- 2018-06-18 KR KR1020180069590A patent/KR102015355B1/ko active Active
- 2018-06-18 MX MX2019015616A patent/MX388833B/es unknown
- 2018-06-18 SG SG11201911602RA patent/SG11201911602RA/en unknown
- 2018-06-18 US US16/622,518 patent/US10870629B2/en active Active
- 2018-06-18 PT PT188208482T patent/PT3643707T/pt unknown
- 2018-06-18 PL PL18820848.2T patent/PL3643707T3/pl unknown
- 2018-06-18 ES ES18820848T patent/ES2912392T3/es active Active
- 2018-06-18 EA EA202090071A patent/EA037781B1/ru not_active IP Right Cessation
- 2018-06-18 CN CN201880041217.3A patent/CN110770212B/zh active Active
-
2019
- 2019-11-26 PH PH12019502665A patent/PH12019502665A1/en unknown
- 2019-12-18 CL CL2019003727A patent/CL2019003727A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN110770212B (zh) | 2022-11-22 |
| DK3643707T3 (da) | 2022-05-09 |
| JP2020524175A (ja) | 2020-08-13 |
| EP3643707A4 (en) | 2021-06-09 |
| RS63205B1 (sr) | 2022-06-30 |
| US10870629B2 (en) | 2020-12-22 |
| PT3643707T (pt) | 2022-05-04 |
| CA3067696A1 (en) | 2018-12-27 |
| EA202090071A1 (ru) | 2020-04-16 |
| AU2018288907B2 (en) | 2020-05-07 |
| AU2018288907A1 (en) | 2020-01-23 |
| SI3643707T1 (sl) | 2022-06-30 |
| CA3067696C (en) | 2022-05-03 |
| KR102015355B1 (ko) | 2019-10-23 |
| CL2019003727A1 (es) | 2020-07-03 |
| EP3643707B1 (en) | 2022-02-23 |
| US20200207724A1 (en) | 2020-07-02 |
| CN110770212A (zh) | 2020-02-07 |
| SG11201911602RA (en) | 2020-01-30 |
| KR20180138169A (ko) | 2018-12-28 |
| MY195426A (en) | 2023-01-20 |
| EA037781B1 (ru) | 2021-05-20 |
| MX388833B (es) | 2025-03-12 |
| PH12019502665A1 (en) | 2020-10-26 |
| ES2912392T3 (es) | 2022-05-25 |
| BR112019027183A2 (pt) | 2020-06-30 |
| PL3643707T3 (pl) | 2023-06-12 |
| EP3643707A1 (en) | 2020-04-29 |
| LT3643707T (lt) | 2022-05-25 |
| JP6913968B2 (ja) | 2021-08-04 |
| MX2019015616A (es) | 2020-02-26 |
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