HRP20220053T1 - Farmaceutski sastavi koji sadrže rpl554 u hfa-134a za primjenu inhalacijom - Google Patents

Farmaceutski sastavi koji sadrže rpl554 u hfa-134a za primjenu inhalacijom Download PDF

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Publication number
HRP20220053T1
HRP20220053T1 HRP20220053TT HRP20220053T HRP20220053T1 HR P20220053 T1 HRP20220053 T1 HR P20220053T1 HR P20220053T T HRP20220053T T HR P20220053TT HR P20220053 T HRP20220053 T HR P20220053T HR P20220053 T1 HRP20220053 T1 HR P20220053T1
Authority
HR
Croatia
Prior art keywords
pharmaceutical composition
liquid pharmaceutical
use according
rpl554
weight
Prior art date
Application number
HRP20220053TT
Other languages
English (en)
Croatian (hr)
Inventor
Peter Lionel Spargo
Phillip A HAYWOOD
Original Assignee
Verona Pharma Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Verona Pharma Plc filed Critical Verona Pharma Plc
Publication of HRP20220053T1 publication Critical patent/HRP20220053T1/hr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4738Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Otolaryngology (AREA)
  • Dispersion Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HRP20220053TT 2018-10-09 2019-10-09 Farmaceutski sastavi koji sadrže rpl554 u hfa-134a za primjenu inhalacijom HRP20220053T1 (hr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1816447.5A GB2578093B (en) 2018-10-09 2018-10-09 Liquid pharmaceutical composition comprising RPL554 and HFA-134A
EP19790718.1A EP3820446B1 (en) 2018-10-09 2019-10-09 Pharmaceutical compositions comprising rpl554 in hfa-134a for administration by inhalation
PCT/GB2019/052863 WO2020074894A1 (en) 2018-10-09 2019-10-09 Pharmaceutical compositions comprising rpl554 in hfa-134a for administration by inhalation

Publications (1)

Publication Number Publication Date
HRP20220053T1 true HRP20220053T1 (hr) 2022-04-15

Family

ID=64394831

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20220053TT HRP20220053T1 (hr) 2018-10-09 2019-10-09 Farmaceutski sastavi koji sadrže rpl554 u hfa-134a za primjenu inhalacijom

Country Status (27)

Country Link
US (2) US20210379053A1 (enExample)
EP (2) EP3960157A1 (enExample)
JP (2) JP7578587B2 (enExample)
KR (1) KR20210073532A (enExample)
CN (1) CN112912064B (enExample)
AU (1) AU2019358585B2 (enExample)
BR (1) BR112021006712A2 (enExample)
CA (1) CA3113167A1 (enExample)
CY (1) CY1124943T1 (enExample)
DK (1) DK3820446T3 (enExample)
ES (1) ES2899744T3 (enExample)
GB (1) GB2578093B (enExample)
HR (1) HRP20220053T1 (enExample)
HU (1) HUE057780T2 (enExample)
IL (1) IL282032A (enExample)
LT (1) LT3820446T (enExample)
MX (2) MX2021003599A (enExample)
MY (1) MY207302A (enExample)
PH (1) PH12021550767A1 (enExample)
PL (1) PL3820446T3 (enExample)
PT (1) PT3820446T (enExample)
RS (1) RS62775B1 (enExample)
SG (1) SG11202102567UA (enExample)
SI (1) SI3820446T1 (enExample)
SM (1) SMT202200044T1 (enExample)
WO (1) WO2020074894A1 (enExample)
ZA (1) ZA202102039B (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI3231444T1 (sl) 2014-05-12 2020-04-30 Verona Pharma Plc Novo zdravljenje
GB201502260D0 (en) 2015-02-11 2015-04-01 Verona Pharma Plc Salt of Pyrimido[6,1-A]Isoquinolin-4-one compound
GB2594480A (en) * 2020-04-28 2021-11-03 Verona Pharma Plc New treatment
GB202202297D0 (en) 2022-02-21 2022-04-06 Verona Pharma Plc Formulation production process
JP2025534762A (ja) * 2022-10-28 2025-10-17 江蘇恒瑞医薬股▲ふん▼有限公司 イソキノリノン系化合物を含む医薬組成物及びその調製方法
EP4378942A1 (en) 2022-12-02 2024-06-05 Sandoz AG Crystal form of a pde3/4 inhibitor
TW202506117A (zh) 2023-06-26 2025-02-16 英商維羅納製藥Plc公司 顆粒組成物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1165558B1 (en) 1999-03-31 2003-09-24 Vernalis Limited Derivatives of pyrimido[6,1-a]isoquinolin-4-one
PH12013500261A1 (en) * 2010-08-09 2013-03-04 Verona Pharma Plc Crystalline form of pyrimidio[6,1-a]isoquinolin-4-one compound
US10022303B2 (en) * 2012-02-28 2018-07-17 Iceutica Pty Ltd. Inhalable pharmaceutical compositions
PT2968313T (pt) * 2013-03-15 2018-02-21 Verona Pharma Plc Combinação de fármacos
SI3231444T1 (sl) * 2014-05-12 2020-04-30 Verona Pharma Plc Novo zdravljenje
DK3494962T3 (da) * 2014-09-15 2021-06-21 Verona Pharma Plc Flydende inhalationsformulering omfattende RPL554
GB201502260D0 (en) * 2015-02-11 2015-04-01 Verona Pharma Plc Salt of Pyrimido[6,1-A]Isoquinolin-4-one compound

Also Published As

Publication number Publication date
CN112912064A (zh) 2021-06-04
LT3820446T (lt) 2021-12-10
KR20210073532A (ko) 2021-06-18
SG11202102567UA (en) 2021-04-29
GB201816447D0 (en) 2018-11-28
ES2899744T3 (es) 2022-03-14
MY207302A (en) 2025-02-15
DK3820446T3 (da) 2021-12-06
US20210379053A1 (en) 2021-12-09
JP2024113096A (ja) 2024-08-21
PH12021550767A1 (en) 2021-10-04
EP3960157A1 (en) 2022-03-02
EP3820446B1 (en) 2021-11-03
BR112021006712A2 (pt) 2021-07-27
WO2020074894A1 (en) 2020-04-16
MX2021003599A (es) 2021-05-28
GB2578093B (en) 2020-11-18
AU2019358585A1 (en) 2021-04-15
JP7578587B2 (ja) 2024-11-06
IL282032A (en) 2021-05-31
EP3820446A1 (en) 2021-05-19
SMT202200044T1 (it) 2022-05-12
JP2022513566A (ja) 2022-02-09
GB2578093A (en) 2020-04-22
CN112912064B (zh) 2025-02-14
AU2019358585B2 (en) 2025-01-16
PT3820446T (pt) 2021-12-03
PL3820446T3 (pl) 2022-03-14
MX2024001499A (es) 2024-02-27
RS62775B1 (sr) 2022-01-31
US20250049781A1 (en) 2025-02-13
CY1124943T1 (el) 2023-01-05
CA3113167A1 (en) 2020-04-16
SI3820446T1 (sl) 2022-01-31
ZA202102039B (en) 2022-08-31
HUE057780T2 (hu) 2022-06-28

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