HRP20220053T1 - Farmaceutski sastavi koji sadrže rpl554 u hfa-134a za primjenu inhalacijom - Google Patents

Farmaceutski sastavi koji sadrže rpl554 u hfa-134a za primjenu inhalacijom Download PDF

Info

Publication number
HRP20220053T1
HRP20220053T1 HRP20220053TT HRP20220053T HRP20220053T1 HR P20220053 T1 HRP20220053 T1 HR P20220053T1 HR P20220053T T HRP20220053T T HR P20220053TT HR P20220053 T HRP20220053 T HR P20220053T HR P20220053 T1 HRP20220053 T1 HR P20220053T1
Authority
HR
Croatia
Prior art keywords
pharmaceutical composition
liquid pharmaceutical
use according
rpl554
weight
Prior art date
Application number
HRP20220053TT
Other languages
English (en)
Croatian (hr)
Inventor
Peter Lionel Spargo
Phillip A HAYWOOD
Original Assignee
Verona Pharma Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Verona Pharma Plc filed Critical Verona Pharma Plc
Publication of HRP20220053T1 publication Critical patent/HRP20220053T1/hr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4738Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Otolaryngology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HRP20220053TT 2018-10-09 2019-10-09 Farmaceutski sastavi koji sadrže rpl554 u hfa-134a za primjenu inhalacijom HRP20220053T1 (hr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1816447.5A GB2578093B (en) 2018-10-09 2018-10-09 Liquid pharmaceutical composition comprising RPL554 and HFA-134A
PCT/GB2019/052863 WO2020074894A1 (en) 2018-10-09 2019-10-09 Pharmaceutical compositions comprising rpl554 in hfa-134a for administration by inhalation
EP19790718.1A EP3820446B1 (en) 2018-10-09 2019-10-09 Pharmaceutical compositions comprising rpl554 in hfa-134a for administration by inhalation

Publications (1)

Publication Number Publication Date
HRP20220053T1 true HRP20220053T1 (hr) 2022-04-15

Family

ID=64394831

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20220053TT HRP20220053T1 (hr) 2018-10-09 2019-10-09 Farmaceutski sastavi koji sadrže rpl554 u hfa-134a za primjenu inhalacijom

Country Status (26)

Country Link
US (2) US20210379053A1 (enExample)
EP (2) EP3820446B1 (enExample)
JP (2) JP7578587B2 (enExample)
CN (1) CN112912064B (enExample)
AU (1) AU2019358585B2 (enExample)
BR (1) BR112021006712A2 (enExample)
CA (1) CA3113167A1 (enExample)
CY (1) CY1124943T1 (enExample)
DK (1) DK3820446T3 (enExample)
ES (1) ES2899744T3 (enExample)
GB (1) GB2578093B (enExample)
HR (1) HRP20220053T1 (enExample)
HU (1) HUE057780T2 (enExample)
IL (1) IL282032B1 (enExample)
LT (1) LT3820446T (enExample)
MX (2) MX2021003599A (enExample)
MY (1) MY207302A (enExample)
PH (1) PH12021550767A1 (enExample)
PL (1) PL3820446T3 (enExample)
PT (1) PT3820446T (enExample)
RS (1) RS62775B1 (enExample)
SG (1) SG11202102567UA (enExample)
SI (1) SI3820446T1 (enExample)
SM (1) SMT202200044T1 (enExample)
WO (1) WO2020074894A1 (enExample)
ZA (1) ZA202102039B (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL3231444T3 (pl) 2014-05-12 2020-05-18 Verona Pharma Plc Nowe leczenie
GB201502260D0 (en) 2015-02-11 2015-04-01 Verona Pharma Plc Salt of Pyrimido[6,1-A]Isoquinolin-4-one compound
GB201916915D0 (en) 2019-11-20 2020-01-01 Amr Centre Ltd Compounds
GB2594480A (en) * 2020-04-28 2021-11-03 Verona Pharma Plc New treatment
GB202202297D0 (en) 2022-02-21 2022-04-06 Verona Pharma Plc Formulation production process
KR20250087621A (ko) * 2022-10-28 2025-06-16 지앙수 헨그루이 파마슈티컬스 컴퍼니 리미티드 이소퀴놀리논계 화합물을 포함하는 약학적 조성물 및 이의 제조 방법
EP4378942A1 (en) 2022-12-02 2024-06-05 Sandoz AG Crystal form of a pde3/4 inhibitor
AU2024309346C1 (en) 2023-06-26 2026-03-12 Verona Pharma Plc Particulate composition comprising ensifentrine

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60005493T2 (de) 1999-03-31 2004-07-01 Vernalis Ltd., Wokingham Pyrimido[6,1-a]isochinolinonderivate
PH12013500261A1 (en) * 2010-08-09 2013-03-04 Verona Pharma Plc Crystalline form of pyrimidio[6,1-a]isoquinolin-4-one compound
NZ629438A (en) * 2012-02-28 2016-10-28 Iceutica Holdings Inc Inhalable pharmaceutical compositions
EP2968312B1 (en) * 2013-03-15 2018-01-31 Verona Pharma PLC Drug combination
PL3231444T3 (pl) * 2014-05-12 2020-05-18 Verona Pharma Plc Nowe leczenie
MY196072A (en) * 2014-09-15 2023-03-13 Verona Pharma Plc Liquid Inhalation Formulation Comprising RPL554
GB201502260D0 (en) * 2015-02-11 2015-04-01 Verona Pharma Plc Salt of Pyrimido[6,1-A]Isoquinolin-4-one compound

Also Published As

Publication number Publication date
PL3820446T3 (pl) 2022-03-14
GB201816447D0 (en) 2018-11-28
RS62775B1 (sr) 2022-01-31
JP2022513566A (ja) 2022-02-09
AU2019358585A1 (en) 2021-04-15
HUE057780T2 (hu) 2022-06-28
BR112021006712A2 (pt) 2021-07-27
CN112912064B (zh) 2025-02-14
GB2578093A (en) 2020-04-22
SMT202200044T1 (it) 2022-05-12
PT3820446T (pt) 2021-12-03
MY207302A (en) 2025-02-15
CY1124943T1 (el) 2023-01-05
IL282032B1 (en) 2026-01-01
IL282032A (en) 2021-05-31
JP2024113096A (ja) 2024-08-21
MX2021003599A (es) 2021-05-28
CN112912064A (zh) 2021-06-04
CA3113167A1 (en) 2020-04-16
SI3820446T1 (sl) 2022-01-31
ES2899744T3 (es) 2022-03-14
DK3820446T3 (da) 2021-12-06
MX2024001499A (es) 2024-02-27
JP7836853B2 (ja) 2026-03-27
EP3820446A1 (en) 2021-05-19
US20250049781A1 (en) 2025-02-13
JP7578587B2 (ja) 2024-11-06
WO2020074894A1 (en) 2020-04-16
AU2019358585B2 (en) 2025-01-16
US20210379053A1 (en) 2021-12-09
ZA202102039B (en) 2022-08-31
SG11202102567UA (en) 2021-04-29
EP3820446B1 (en) 2021-11-03
KR20210073532A (ko) 2021-06-18
LT3820446T (lt) 2021-12-10
PH12021550767A1 (en) 2021-10-04
EP3960157A1 (en) 2022-03-02
GB2578093B (en) 2020-11-18

Similar Documents

Publication Publication Date Title
HRP20220053T1 (hr) Farmaceutski sastavi koji sadrže rpl554 u hfa-134a za primjenu inhalacijom
JP2024113096A5 (enExample)
MX2024002495A (es) Inhaladores de dosis medida y composiciones en suspension.
UA107499C2 (uk) Склад сухого порошку, який містить антимускариновий засіб
HRP20151214T4 (hr) Pripravak za inhalaciju koji sadrži aklidinij za liječenje kronične opstruktivne plućne bolesti
EA201591869A1 (ru) Композиция, содержащая для повышения стабильности лекарственной формы по меньшей мере два сухих порошка, получаемых распылительной сушкой
RU2013103534A (ru) Лечение легочных инфекций с помощью введения тобрамицина путем аэролизации
JP2016534142A5 (enExample)
UY34838A (es) Nueva forma de dosificación y formulación
FI3412277T3 (fi) Kortikosteroidia ja beeta-adrenergista ainetta käsittävä kuivajauheformulaatio annettavaksi inhalaatiolla
MX2017004476A (es) Composicion que comprende al menos un polvo seco obtenido por secado por atomizacion para aumentar la estabilidad de la formulacion.
HUE030983T2 (en) Inhalable medicine containing thiotropium
WO2017069721A1 (en) Antiviral pharmaceutical composition
JP2008540506A5 (enExample)
JP5938476B2 (ja) 呼吸器疾患を治療するための定量噴霧式吸入剤を調製する方法
MY187442A (en) A pharmaceutical composition containing budesonide and formoterol
ME02398B (me) Farmaceutske aerosolne formulacije formoterola i beklometazon dipropionata
EP2821061A1 (en) Novel inhalation formulations
RU2013148786A (ru) Улучшенный состав суспензии кортикостероида для ингаляционного введения
CA2930173A1 (en) An inhalable medicament
Das et al. Understanding the Respiratory Delivery of High Dose Anti‐Tubercular Drugs
WO2023177366A1 (en) Use of active ingredient used against viral diseases with pressurized metered dose inhaler in the treatment of covid-19 and other viral lung diseases
MX372705B (es) Composición farmacéutica que contiene budesonida y formoterol
JP2011509936A5 (enExample)
Vatanparast et al. Efficiency improvement of fluticasone propionate dry powder formulation for inhalation in pulmonary patients