SI3820446T1 - Farmacevtski sestavki, ki vsebujejo RPL554 v HFA-134A za uporabo z vdihavanjem - Google Patents

Farmacevtski sestavki, ki vsebujejo RPL554 v HFA-134A za uporabo z vdihavanjem

Info

Publication number
SI3820446T1
SI3820446T1 SI201930145T SI201930145T SI3820446T1 SI 3820446 T1 SI3820446 T1 SI 3820446T1 SI 201930145 T SI201930145 T SI 201930145T SI 201930145 T SI201930145 T SI 201930145T SI 3820446 T1 SI3820446 T1 SI 3820446T1
Authority
SI
Slovenia
Prior art keywords
hfa
pharmaceutical compositions
compositions containing
inhalation use
rpl554
Prior art date
Application number
SI201930145T
Other languages
English (en)
Slovenian (sl)
Inventor
Peter Lionel Spargo
Phillip A Haywood
Original Assignee
Verona Pharma Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Verona Pharma Plc filed Critical Verona Pharma Plc
Publication of SI3820446T1 publication Critical patent/SI3820446T1/sl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4738Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Otolaryngology (AREA)
  • Dispersion Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SI201930145T 2018-10-09 2019-10-09 Farmacevtski sestavki, ki vsebujejo RPL554 v HFA-134A za uporabo z vdihavanjem SI3820446T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1816447.5A GB2578093B (en) 2018-10-09 2018-10-09 Liquid pharmaceutical composition comprising RPL554 and HFA-134A
EP19790718.1A EP3820446B1 (en) 2018-10-09 2019-10-09 Pharmaceutical compositions comprising rpl554 in hfa-134a for administration by inhalation
PCT/GB2019/052863 WO2020074894A1 (en) 2018-10-09 2019-10-09 Pharmaceutical compositions comprising rpl554 in hfa-134a for administration by inhalation

Publications (1)

Publication Number Publication Date
SI3820446T1 true SI3820446T1 (sl) 2022-01-31

Family

ID=64394831

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201930145T SI3820446T1 (sl) 2018-10-09 2019-10-09 Farmacevtski sestavki, ki vsebujejo RPL554 v HFA-134A za uporabo z vdihavanjem

Country Status (27)

Country Link
US (2) US20210379053A1 (enExample)
EP (2) EP3960157A1 (enExample)
JP (2) JP7578587B2 (enExample)
KR (1) KR20210073532A (enExample)
CN (1) CN112912064B (enExample)
AU (1) AU2019358585B2 (enExample)
BR (1) BR112021006712A2 (enExample)
CA (1) CA3113167A1 (enExample)
CY (1) CY1124943T1 (enExample)
DK (1) DK3820446T3 (enExample)
ES (1) ES2899744T3 (enExample)
GB (1) GB2578093B (enExample)
HR (1) HRP20220053T1 (enExample)
HU (1) HUE057780T2 (enExample)
IL (1) IL282032A (enExample)
LT (1) LT3820446T (enExample)
MX (2) MX2021003599A (enExample)
MY (1) MY207302A (enExample)
PH (1) PH12021550767A1 (enExample)
PL (1) PL3820446T3 (enExample)
PT (1) PT3820446T (enExample)
RS (1) RS62775B1 (enExample)
SG (1) SG11202102567UA (enExample)
SI (1) SI3820446T1 (enExample)
SM (1) SMT202200044T1 (enExample)
WO (1) WO2020074894A1 (enExample)
ZA (1) ZA202102039B (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL3231444T3 (pl) 2014-05-12 2020-05-18 Verona Pharma Plc Nowe leczenie
GB201502260D0 (en) 2015-02-11 2015-04-01 Verona Pharma Plc Salt of Pyrimido[6,1-A]Isoquinolin-4-one compound
GB2594480A (en) * 2020-04-28 2021-11-03 Verona Pharma Plc New treatment
GB202202297D0 (en) 2022-02-21 2022-04-06 Verona Pharma Plc Formulation production process
KR20250087621A (ko) * 2022-10-28 2025-06-16 지앙수 헨그루이 파마슈티컬스 컴퍼니 리미티드 이소퀴놀리논계 화합물을 포함하는 약학적 조성물 및 이의 제조 방법
EP4378942A1 (en) 2022-12-02 2024-06-05 Sandoz AG Crystal form of a pde3/4 inhibitor
US12194045B1 (en) 2023-06-26 2025-01-14 Verona Pharma Plc Particulate composition

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60005493T2 (de) 1999-03-31 2004-07-01 Vernalis Ltd., Wokingham Pyrimido[6,1-a]isochinolinonderivate
MX345802B (es) * 2010-08-09 2017-02-16 Verona Pharma Plc * Forma cristalina de compuesto pirimido [6, 1-a] isoquinolin-4-ona.
RU2697862C2 (ru) * 2012-02-28 2019-08-21 Айсьютика Холдингз Инк. Ингаляционные фармацевтические композиции
RU2666624C2 (ru) * 2013-03-15 2018-09-11 ВЕРОНА ФАРМА ПиэЛСи Комбинация лекарственных средств
PL3231444T3 (pl) * 2014-05-12 2020-05-18 Verona Pharma Plc Nowe leczenie
RU2699995C2 (ru) * 2014-09-15 2019-09-12 ВЕРОНА ФАРМА ПиэЛСи Жидкая ингаляционная композиция, содержащая rpl 554
GB201502260D0 (en) * 2015-02-11 2015-04-01 Verona Pharma Plc Salt of Pyrimido[6,1-A]Isoquinolin-4-one compound

Also Published As

Publication number Publication date
SG11202102567UA (en) 2021-04-29
JP2024113096A (ja) 2024-08-21
AU2019358585A1 (en) 2021-04-15
US20250049781A1 (en) 2025-02-13
HUE057780T2 (hu) 2022-06-28
US20210379053A1 (en) 2021-12-09
JP7578587B2 (ja) 2024-11-06
EP3960157A1 (en) 2022-03-02
JP2022513566A (ja) 2022-02-09
SMT202200044T1 (it) 2022-05-12
ES2899744T3 (es) 2022-03-14
LT3820446T (lt) 2021-12-10
MY207302A (en) 2025-02-15
CN112912064A (zh) 2021-06-04
AU2019358585B2 (en) 2025-01-16
RS62775B1 (sr) 2022-01-31
EP3820446B1 (en) 2021-11-03
DK3820446T3 (da) 2021-12-06
CA3113167A1 (en) 2020-04-16
GB2578093A (en) 2020-04-22
BR112021006712A2 (pt) 2021-07-27
GB201816447D0 (en) 2018-11-28
MX2021003599A (es) 2021-05-28
CN112912064B (zh) 2025-02-14
PL3820446T3 (pl) 2022-03-14
EP3820446A1 (en) 2021-05-19
WO2020074894A1 (en) 2020-04-16
MX2024001499A (es) 2024-02-27
CY1124943T1 (el) 2023-01-05
IL282032A (en) 2021-05-31
PT3820446T (pt) 2021-12-03
ZA202102039B (en) 2022-08-31
GB2578093B (en) 2020-11-18
PH12021550767A1 (en) 2021-10-04
KR20210073532A (ko) 2021-06-18
HRP20220053T1 (hr) 2022-04-15

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