HRP20211079T1 - Konstrukcije sirp-alfa varijante i njihove uporabe - Google Patents

Konstrukcije sirp-alfa varijante i njihove uporabe Download PDF

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Publication number
HRP20211079T1
HRP20211079T1 HRP20211079TT HRP20211079T HRP20211079T1 HR P20211079 T1 HRP20211079 T1 HR P20211079T1 HR P20211079T T HRP20211079T T HR P20211079TT HR P20211079 T HRP20211079 T HR P20211079T HR P20211079 T1 HRP20211079 T1 HR P20211079T1
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HR
Croatia
Prior art keywords
cancer
sirp
variant
construction
seq
Prior art date
Application number
HRP20211079TT
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English (en)
Croatian (hr)
Inventor
Laura Deming
Corey Goodman
Jaume Pons
Bang Janet Sim
Marija VRLJIC
Original Assignee
ALX Oncology Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from TW104125902A external-priority patent/TWI702228B/zh
Application filed by ALX Oncology Inc. filed Critical ALX Oncology Inc.
Publication of HRP20211079T1 publication Critical patent/HRP20211079T1/hr

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
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    • C07—ORGANIC CHEMISTRY
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    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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    • C—CHEMISTRY; METALLURGY
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    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
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TW104125902A TWI702228B (zh) 2014-08-08 2015-08-10 信號調節蛋白α（ｓｉｇｎａｌ-ｒｅｇｕｌａｔｏｒｙ ｐｒｏｔｅｉｎ α， ＳＩＲＰ-α）變體構築物及其用途
US14/971,931 US20160319256A9 (en) 2014-08-08 2015-12-16 Sirp-alpha variant constructs and uses thereof
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EP3128005B1 (en) 2021-04-14
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