HRP20211079T1 - Konstrukcije sirp-alfa varijante i njihove uporabe - Google Patents
Konstrukcije sirp-alfa varijante i njihove uporabe Download PDFInfo
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- HRP20211079T1 HRP20211079T1 HRP20211079TT HRP20211079T HRP20211079T1 HR P20211079 T1 HRP20211079 T1 HR P20211079T1 HR P20211079T T HRP20211079T T HR P20211079TT HR P20211079 T HRP20211079 T HR P20211079T HR P20211079 T1 HRP20211079 T1 HR P20211079T1
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- Prior art keywords
- cancer
- sirp
- variant
- construction
- seq
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Classifications
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| MA53493A (fr) * | 2018-08-31 | 2021-07-07 | Alx Oncology Inc | Polypeptides leurres |
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| CN115551892A (zh) * | 2020-03-26 | 2022-12-30 | 艾提欧生物疗法有限公司 | 用于耗竭调节性t细胞的双特异性融合蛋白 |
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| JP2024520902A (ja) | 2021-05-13 | 2024-05-27 | エーエルエックス オンコロジー インコーポレイテッド | がんを治療するための併用療法 |
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| EP3766511A1 (en) * | 2012-01-17 | 2021-01-20 | The Board of Trustees of the Leland Stanford Junior University | High affinity sirp-alpha reagents |
| US9428553B2 (en) * | 2012-02-10 | 2016-08-30 | City Of Hope | Meditopes and meditope-binding antibodies and uses thereof |
| CA2876904C (en) * | 2012-06-22 | 2019-12-03 | Cytomx Therapeutics, Inc. | Anti-jagged 1/jagged 2 cross-reactive antibodies, activatable anti-jagged antibodies and methods of use thereof |
| JP6335189B2 (ja) * | 2012-12-17 | 2018-05-30 | トリリアム・セラピューティクス・インコーポレイテッドTrillium Therapeutics Inc. | SIRPアルファ−Fc融合体でのCD47+疾患細胞の治療 |
| US9873747B2 (en) * | 2013-01-31 | 2018-01-23 | Thomas Jefferson University | Fusion proteins that facilitate cancer cell destruction |
| CN106459153B (zh) * | 2014-01-31 | 2021-12-21 | 西托姆克斯治疗公司 | 蛋白裂解酶和u型纤溶酶原激活物的底物和其它可裂解部分及其使用方法 |
| CN113621075B (zh) * | 2014-08-08 | 2024-09-20 | Alx肿瘤生物技术公司 | SIRP-α变体构建体及其用途 |
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