HRP20200941T1 - FARMACEUTSKI PRIPRAVAK KOJI SADRŽI REKOMBINANTNI hCG - Google Patents
FARMACEUTSKI PRIPRAVAK KOJI SADRŽI REKOMBINANTNI hCG Download PDFInfo
- Publication number
- HRP20200941T1 HRP20200941T1 HRP20200941TT HRP20200941T HRP20200941T1 HR P20200941 T1 HRP20200941 T1 HR P20200941T1 HR P20200941T T HRP20200941T T HR P20200941TT HR P20200941 T HRP20200941 T HR P20200941T HR P20200941 T1 HRP20200941 T1 HR P20200941T1
- Authority
- HR
- Croatia
- Prior art keywords
- pharmaceutical preparation
- recombinant hcg
- per
- cell line
- rhcg
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1081—Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/005—Glycopeptides, glycoproteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y204/00—Glycosyltransferases (2.4)
- C12Y204/99—Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Endocrinology (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Reproductive Health (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biophysics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Toxicology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Pregnancy & Childbirth (AREA)
- Gynecology & Obstetrics (AREA)
- Diabetes (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09252360 | 2009-10-05 | ||
| PCT/GB2010/001854 WO2011042688A1 (en) | 2009-10-05 | 2010-10-04 | Pharmaceutical preparation comprising recombinant hcg |
| EP10763000.6A EP2486051B1 (en) | 2009-10-05 | 2010-10-04 | Pharmaceutical preparation comprising recombinant hcg |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20200941T1 true HRP20200941T1 (hr) | 2020-09-18 |
Family
ID=41471027
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20200941TT HRP20200941T1 (hr) | 2009-10-05 | 2010-10-04 | FARMACEUTSKI PRIPRAVAK KOJI SADRŽI REKOMBINANTNI hCG |
Country Status (25)
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI488640B (zh) | 2008-04-16 | 2015-06-21 | Ferring Int Ct Sa | 藥學製劑 |
| TWI604850B (zh) * | 2009-10-05 | 2017-11-11 | 菲瑞茵國際中心股份有限公司 | 藥學製劑 |
| CA2831486A1 (en) | 2011-03-31 | 2012-10-04 | Ferring B.V. | Pharmaceutical preparation |
| AR090095A1 (es) * | 2011-06-06 | 2014-10-22 | Ferring Bv | Preparacion farmaceutica que comprende hormona estimulante del foliculo recombinante |
| JO3092B1 (ar) * | 2011-08-08 | 2017-03-15 | Ferring Bv | مركب لتحفيز مسيطر عليه للمبيض |
| AU2012340501A1 (en) * | 2011-12-19 | 2013-07-11 | Grifols, S.A. | Compositions, methods, and kits for preparing sialylated recombinant proteins |
| CN108646019B (zh) | 2012-12-10 | 2021-06-25 | 生化学工业株式会社 | 新重组因子c、其制造方法、及内毒素的测定法 |
| JP2018500934A (ja) * | 2014-12-22 | 2018-01-18 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | Ｃｍｐ依存性シアリダーゼ活性 |
| MX389908B (es) | 2015-04-24 | 2025-03-20 | Ferring Bv | Metodo de produccion de gonadotrofina. |
| EP3313859B1 (en) | 2015-06-26 | 2019-11-20 | Ferring BV | Methods of purification and/or viral inactivation |
| EP3787667B1 (en) * | 2018-04-30 | 2025-03-26 | Ferring B.V. | Composition for controlled ovarian stimulation |
| EP4100425A1 (en) * | 2020-02-05 | 2022-12-14 | Novartis AG | Cho cell expressing il-15 heterodimers |
| CN116199742B (zh) * | 2022-07-06 | 2025-01-24 | 华兰基因工程有限公司 | 一种重组人绒毛膜促性腺激素Fc融合蛋白制备方法 |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4840896A (en) * | 1983-11-02 | 1989-06-20 | Integrated Genetics, Inc. | Heteropolymeric protein |
| DK49987A (da) | 1987-01-30 | 1988-07-31 | Nordisk Gentofte | Fremgangsmaade til behandling af infertilitet og middel til anvendelse ved fremgangsmaaden |
| IT1206302B (it) | 1987-06-26 | 1989-04-14 | Serono Cesare Ist Ricerca | Ormone follicolo-stimolante urinario |
| UA61053C2 (en) * | 1995-03-21 | 2003-11-17 | Applied Research Systems | Stable liquid pharmaceutical compositions, method for its production and delivery form |
| IL122732A0 (en) * | 1997-01-15 | 1998-08-16 | Akzo Nobel Nv | Liquid gonadotropin-containing formulation its preparation and a device containing same |
| CN100404551C (zh) | 1997-06-25 | 2008-07-23 | 雪兰诺实验室有限公司 | 二硫键交联的糖蛋白激素类似物及其制备和应用 |
| US6500627B1 (en) * | 1998-02-03 | 2002-12-31 | The Trustees Of Columbia University In The City Of New York | Methods for predicting pregnancy outcome in a subject by HCG assay |
| EP1176976B2 (en) * | 1999-05-07 | 2015-10-21 | Laboratoires Serono SA | Use of lh administered in mid- or late-follicular phase for the treatment of anovulatory women |
| MXPA02007871A (es) | 2000-02-22 | 2003-02-10 | Applied Research Systems | Proceso para la purificacion de gonadotropina corionica humana (hcg) y gonadotropina corionica humana recombinante purificada mediante este proceso. |
| PL369098A1 (en) | 2001-09-12 | 2005-04-18 | Applied Research Systems Ars Holding N.V. | Use of hcg in controlled ovarian hyperstimulation |
| EP1621549A3 (en) * | 2001-10-22 | 2006-03-01 | Applied Research Systems ARS Holding N.V. | Compositions of fsh with high sialylation degree and their use for the preparation of medicinaments |
| BR0213402A (pt) | 2001-10-29 | 2004-10-13 | Crucell Holland Bv | Métodos para identificar uma célula de mamìfero capaz de produzir uma molécula proteinácea, para selecionar uma célula de mamìfero capaz de produzir uma molécula proteinácea, para se obter uma célula de mamìfero a partir de uma população heterogênea de células, e para produzir uma molécula proteinácea, composição farmaceuticamente aceitável, eritropoietina recombinantemente produzida, usos de uma célula de mamìfero, da eritropoietina recombinantemente produzida, e de uma composição de moléculas semelhantes à eritropoietina, preparação farmacêutica, método para o tratamento preventivo e/ou terapêutico de um distúrbio, composição de moléculas semelhates à eritropoietina, métodos para produzir, em uma célula de mamìfero, moléculas proteináceas, para produzir uma fração enriquecida em uma molécula proteinácea, e para fracionar uma mistura que contém moléculas proteináceas, fração, e, usos de uma fração ou composição, e de eritropoietina recombinantemente produzìvel em uma célula de mamìfero |
| AU2002224199A1 (en) * | 2001-10-29 | 2003-06-23 | Crucell Holland B.V. | Methods and means for producing proteins with predetermined post-translational modifications |
| CN1374525A (zh) * | 2001-12-31 | 2002-10-16 | 陕西超英生物医学研究开发有限公司 | 一种抗体芯片、其制备技术及其检测方法 |
| AU2004226353A1 (en) * | 2003-04-01 | 2004-10-14 | Laboratoires Serono Sa | Inhibitors of phosphodiesterases in infertility |
| EP2055189A1 (en) * | 2003-04-09 | 2009-05-06 | Neose Technologies, Inc. | Glycopegylation methods and proteins/peptides produced by the methods |
| US20040248784A1 (en) * | 2003-06-03 | 2004-12-09 | Marco Filicori | Unitary combinations of FSH and hCG |
| JP4518464B2 (ja) | 2003-06-30 | 2010-08-04 | ミヨシ油脂株式会社 | 紙類処理剤及び紙類 |
| EP1654353B1 (en) * | 2003-08-18 | 2013-05-22 | Glycotope GmbH | Tumour cell lines nm-f9 (dsm acc2606) and nm-d4 (dsm acc2605), uses threreof |
| DK1711834T3 (da) | 2004-02-04 | 2010-11-29 | Centre Nat Rech Scient | Fremgangsmåde til screening af glycoform-specifikke antistoffer |
| CN1926242B (zh) * | 2004-02-13 | 2013-01-16 | 格莱克托普有限公司 | 高活性糖蛋白加工条件及其有效生产方法 |
| EP1861124A2 (en) * | 2005-03-11 | 2007-12-05 | Fresenius Kabi Deutschland GmbH | Production of bioactive glycoproteins from inactive starting materials by conjugation with hydroxyalkylstarch |
| JP2009504985A (ja) | 2005-08-15 | 2009-02-05 | シーメンス ヴィディーオー オートモーティヴ コーポレイション | ディーゼル車排気への炭化水素計量弁 |
| RU2309411C2 (ru) * | 2005-11-24 | 2007-10-27 | Ростовский НИИ акушерства и педиатрии МЗ РФ | Способ отбора пациенток с синдромом "пустых" фолликулов для проведения программы эко и пэ донорскими ооцитами |
| KR100809945B1 (ko) * | 2006-02-01 | 2008-03-05 | 대한민국 | 인체장내정상세균총 특이반응 ｄｎａ칩 및 이를 이용한인체장내정상세균총의 변화에 의한 인체 위해성의 평가방법 |
| US9187532B2 (en) * | 2006-07-21 | 2015-11-17 | Novo Nordisk A/S | Glycosylation of peptides via O-linked glycosylation sequences |
| WO2008057683A2 (en) * | 2006-10-03 | 2008-05-15 | Novo Nordisk A/S | Methods for the purification of polypeptide conjugates |
| TWI488640B (zh) * | 2008-04-16 | 2015-06-21 | Ferring Int Ct Sa | 藥學製劑 |
| TWI604850B (zh) * | 2009-10-05 | 2017-11-11 | 菲瑞茵國際中心股份有限公司 | 藥學製劑 |
| CA2831486A1 (en) * | 2011-03-31 | 2012-10-04 | Ferring B.V. | Pharmaceutical preparation |
| JO3092B1 (ar) * | 2011-08-08 | 2017-03-15 | Ferring Bv | مركب لتحفيز مسيطر عليه للمبيض |
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2010
- 2010-09-27 TW TW104140348A patent/TWI604850B/zh active
- 2010-09-27 TW TW099132570A patent/TWI532495B/zh active
- 2010-10-04 PT PT107630006T patent/PT2486051T/pt unknown
- 2010-10-04 RU RU2016118236A patent/RU2724528C2/ru active
- 2010-10-04 KR KR1020217003233A patent/KR20210014767A/ko not_active Ceased
- 2010-10-04 ES ES19190372T patent/ES3036152T3/es active Active
- 2010-10-04 KR KR1020197016021A patent/KR102213154B1/ko active Active
- 2010-10-04 KR KR1020197007226A patent/KR101987982B1/ko active Active
- 2010-10-04 ES ES10763000T patent/ES2798258T3/es active Active
- 2010-10-04 KR KR1020177034392A patent/KR20170133531A/ko not_active Withdrawn
- 2010-10-04 LT LTEP10763000.6T patent/LT2486051T/lt unknown
- 2010-10-04 HU HUE10763000A patent/HUE050793T2/hu unknown
- 2010-10-04 DK DK10763000.6T patent/DK2486051T3/da active
- 2010-10-04 MX MX2012003951A patent/MX2012003951A/es active IP Right Grant
- 2010-10-04 AU AU2010304922A patent/AU2010304922B2/en active Active
- 2010-10-04 US US13/500,274 patent/US8975226B2/en active Active
- 2010-10-04 WO PCT/GB2010/001854 patent/WO2011042688A1/en not_active Ceased
- 2010-10-04 KR KR1020127008827A patent/KR101804479B1/ko active Active
- 2010-10-04 CN CN201610832288.8A patent/CN107050434B/zh active Active
- 2010-10-04 BR BR112012007990A patent/BR112012007990A2/pt not_active Application Discontinuation
- 2010-10-04 KR KR1020237001308A patent/KR20230012104A/ko active Pending
- 2010-10-04 CA CA2776790A patent/CA2776790A1/en active Pending
- 2010-10-04 HR HRP20200941TT patent/HRP20200941T1/hr unknown
- 2010-10-04 IN IN2073DEN2012 patent/IN2012DN02073A/en unknown
- 2010-10-04 RS RS20200698A patent/RS60413B1/sr unknown
- 2010-10-04 JP JP2012532657A patent/JP6176924B2/ja active Active
- 2010-10-04 EP EP19190372.3A patent/EP3611185B1/en active Active
- 2010-10-04 RU RU2012112907/10A patent/RU2588650C2/ru active
- 2010-10-04 KR KR1020217037028A patent/KR102489143B1/ko active Active
- 2010-10-04 PL PL10763000T patent/PL2486051T3/pl unknown
- 2010-10-04 EP EP10763000.6A patent/EP2486051B1/en active Active
- 2010-10-04 SI SI201032015T patent/SI2486051T1/sl unknown
- 2010-10-05 AR ARP100103608A patent/AR079876A1/es not_active Application Discontinuation
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2012
- 2012-03-08 IL IL218548A patent/IL218548A/en active IP Right Grant
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2014
- 2014-05-21 US US14/283,904 patent/US9676835B2/en active Active
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2015
- 2015-11-09 JP JP2015219480A patent/JP6310440B2/ja active Active
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2017
- 2017-02-23 IL IL250733A patent/IL250733B/en active IP Right Grant
- 2017-05-03 US US15/586,010 patent/US10526390B2/en active Active
- 2017-10-24 JP JP2017205012A patent/JP6580104B2/ja active Active
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2019
- 2019-06-20 IL IL267556A patent/IL267556A/en unknown
- 2019-08-27 JP JP2019154226A patent/JP7292153B2/ja active Active
- 2019-12-10 US US16/709,810 patent/US11292824B2/en active Active
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2020
- 2020-02-17 JO JOP/2020/0039A patent/JOP20200039A1/ar unknown
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2021
- 2021-07-12 JP JP2021114833A patent/JP7196244B2/ja active Active
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2022
- 2022-03-30 US US17/709,296 patent/US12234272B2/en active Active
- 2022-05-27 AR ARP220101408A patent/AR125991A2/es not_active Application Discontinuation
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2023
- 2023-02-22 JP JP2023025781A patent/JP2023075144A/ja active Pending
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