HRP20161165T1 - Modafinil za uporabu u liječenju ovisnosti o kokainu - Google Patents
Modafinil za uporabu u liječenju ovisnosti o kokainu Download PDFInfo
- Publication number
- HRP20161165T1 HRP20161165T1 HRP20161165TT HRP20161165T HRP20161165T1 HR P20161165 T1 HRP20161165 T1 HR P20161165T1 HR P20161165T T HRP20161165T T HR P20161165TT HR P20161165 T HRP20161165 T HR P20161165T HR P20161165 T1 HRP20161165 T1 HR P20161165T1
- Authority
- HR
- Croatia
- Prior art keywords
- modafinil
- composition
- use according
- treatment
- cocaine addicts
- Prior art date
Links
- 229960001165 modafinil Drugs 0.000 title claims 6
- ZPUCINDJVBIVPJ-LJISPDSOSA-N cocaine Chemical compound O([C@H]1C[C@@H]2CC[C@@H](N2C)[C@H]1C(=O)OC)C(=O)C1=CC=CC=C1 ZPUCINDJVBIVPJ-LJISPDSOSA-N 0.000 title 2
- YFGHCGITMMYXAQ-UHFFFAOYSA-N 2-[(diphenylmethyl)sulfinyl]acetamide Chemical compound C=1C=CC=CC=1C(S(=O)CC(=O)N)C1=CC=CC=C1 YFGHCGITMMYXAQ-UHFFFAOYSA-N 0.000 title 1
- 229960003920 cocaine Drugs 0.000 title 1
- 239000000203 mixture Substances 0.000 claims 7
- 239000012530 fluid Substances 0.000 claims 2
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical group O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 claims 1
- 208000022497 Cocaine-Related disease Diseases 0.000 claims 1
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical group OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims 1
- 229930195725 Mannitol Natural products 0.000 claims 1
- 229960004977 anhydrous lactose Drugs 0.000 claims 1
- 201000006145 cocaine dependence Diseases 0.000 claims 1
- 206010013663 drug dependence Diseases 0.000 claims 1
- 239000008187 granular material Substances 0.000 claims 1
- 239000000594 mannitol Substances 0.000 claims 1
- 235000010355 mannitol Nutrition 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 238000006467 substitution reaction Methods 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
- A61K9/4825—Proteins, e.g. gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Addiction (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Psychiatry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
Claims (7)
1. Farmaceutski sastav na bazi S-modafinila, koji se upotrebljava u zamjenskom liječenju ovisnosti o kokainu, naznačen time, da se S-modafinil dobiva uporabom tehnologije superkritičnih fluida, pri čemu se navedeni S-modafinil apsorbira na površini granula proizvedenih u inertnom nosaču.
2. Sastav za uporabu prema zahtjevu 1, naznačen time, da navedeni fluid je CO2.
3. Sastav za uporabu prema jednom od zahtjeva 1 ili 2, naznačen time, da navedeni nosač je bezvodna laktoza.
4. Sastav za uporabu prema jednom od zahtjeva 1 ili 2, naznačen time, da navedeni nosač je manitol.
5. Sastav za uporabu prema bilo kojem od zahtjeva 1 do 4, naznačen time, da je navedeni sastav u obliku tablete.
6. Sastav za uporabu prema zahtjevu 5, naznačen time, da navedena tableta sadrži od 25 do 200 mg S-modafinila.
7. Sastav za uporabu prema zahtjevu 6, naznačen time, da navedena tableta sadrži od 50 do 100 mg S-modafinila.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR1200581A FR2987267B1 (fr) | 2012-02-28 | 2012-02-28 | Application du modafinil dans le traitement de substitution des cacainomanes |
| EP13715263.3A EP2819655B1 (fr) | 2012-02-28 | 2013-02-25 | Modafinil pour son utilisation dans le traitement des cocaïnomanes |
| PCT/FR2013/000052 WO2013128088A1 (fr) | 2012-02-28 | 2013-02-25 | Application du modafinil dans le traitement des cocaïnomanes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20161165T1 true HRP20161165T1 (hr) | 2016-11-04 |
Family
ID=48083447
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20161165TT HRP20161165T1 (hr) | 2012-02-28 | 2016-09-12 | Modafinil za uporabu u liječenju ovisnosti o kokainu |
Country Status (33)
| Country | Link |
|---|---|
| US (1) | US20150073055A1 (hr) |
| EP (1) | EP2819655B1 (hr) |
| JP (1) | JP6163169B2 (hr) |
| KR (1) | KR101897855B1 (hr) |
| CN (1) | CN104159575B (hr) |
| AR (1) | AR090169A1 (hr) |
| AU (1) | AU2013224831B2 (hr) |
| BR (1) | BR112014020626A2 (hr) |
| CA (1) | CA2863159C (hr) |
| CL (1) | CL2014002203A1 (hr) |
| CY (1) | CY1118166T1 (hr) |
| DK (1) | DK2819655T3 (hr) |
| EA (1) | EA025692B1 (hr) |
| ES (1) | ES2593276T3 (hr) |
| FR (1) | FR2987267B1 (hr) |
| HR (1) | HRP20161165T1 (hr) |
| HU (1) | HUE030737T2 (hr) |
| IL (1) | IL234009B (hr) |
| IN (1) | IN2014DN07831A (hr) |
| LT (1) | LT2819655T (hr) |
| MX (1) | MX348222B (hr) |
| NZ (1) | NZ628009A (hr) |
| PH (1) | PH12014501837A1 (hr) |
| PL (1) | PL2819655T3 (hr) |
| PT (1) | PT2819655T (hr) |
| RS (1) | RS55238B1 (hr) |
| SG (1) | SG11201405316WA (hr) |
| SI (1) | SI2819655T1 (hr) |
| SM (1) | SMT201600363B (hr) |
| TW (1) | TWI626042B (hr) |
| UA (1) | UA113301C2 (hr) |
| WO (1) | WO2013128088A1 (hr) |
| ZA (1) | ZA201405910B (hr) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105055404B (zh) * | 2015-08-19 | 2017-07-18 | 四川大学 | Hmgcs2抑制剂在制备治疗可卡因成瘾的药物中的用途 |
| CN105055412B (zh) * | 2015-08-20 | 2018-06-19 | 四川大学 | Nampt抑制剂在制备治疗可卡因成瘾的药物中的用途 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5618845A (en) * | 1994-10-06 | 1997-04-08 | Cephalon, Inc. | Acetamide derivative having defined particle size |
| FR2771004B1 (fr) | 1997-11-19 | 2000-02-18 | Inst Curie | Utilisation de derives de benzhydryl sulfinyle pour la fabrication de medicaments ayant un effet eveillant dans des situations de troubles de la vigilance d'origine medicamenteuse |
| US20010034373A1 (en) | 2000-02-09 | 2001-10-25 | Matthew Miller | Low dose modafinil for enhancement of cognitive function |
| BR0114814A (pt) * | 2000-10-11 | 2005-01-25 | Cephalon Inc | Composições compreendendo composto de modafinila e seu uso |
| US20040006532A1 (en) | 2001-03-20 | 2004-01-08 | David Lawrence | Network access risk management |
| US20060024370A1 (en) * | 2004-07-29 | 2006-02-02 | Cephalon France | Modafinil oral lyophilizate |
| US7093476B2 (en) | 2004-09-15 | 2006-08-22 | Ut-Battelle, Llc | Method for fabricating thin californium-containing radioactive source wires |
| WO2007013962A2 (en) * | 2005-07-21 | 2007-02-01 | Neurohealing Pharmaceuticals, Inc. | Rapid onset and short term modafinil compositions and methods of use thereof |
| BRPI0714173A2 (pt) * | 2006-07-12 | 2012-12-25 | Elan Pharma Int Ltd | composiÇço nanoparticulada estÁvel,mÉtodos para preparar a composiÇço, para prevenir e/ou tratar estados de doenÇas, sintomas, sÍndromes e condiÇÕes do sistema nervoso central, para melhorar ou manter a biodisponibilidade de modafinil, e para tratar distérbio com base neurolàgica, composiÇço farmacÊutica, e forma de dosagem |
| EP1980240A1 (en) * | 2007-04-11 | 2008-10-15 | Cephalon France | Lyophilized pharmaceutical compositions and methods of making and using same |
| US8173169B2 (en) * | 2007-07-11 | 2012-05-08 | Hikma Pharmaceuticals | Formulation and process for the preparation of modafinil |
-
2012
- 2012-02-28 FR FR1200581A patent/FR2987267B1/fr not_active Expired - Fee Related
-
2013
- 2013-02-25 IN IN7831DEN2014 patent/IN2014DN07831A/en unknown
- 2013-02-25 LT LTEP13715263.3T patent/LT2819655T/lt unknown
- 2013-02-25 RS RS20160882A patent/RS55238B1/sr unknown
- 2013-02-25 MX MX2014010237A patent/MX348222B/es active IP Right Grant
- 2013-02-25 DK DK13715263.3T patent/DK2819655T3/en active
- 2013-02-25 PL PL13715263T patent/PL2819655T3/pl unknown
- 2013-02-25 NZ NZ628009A patent/NZ628009A/en not_active IP Right Cessation
- 2013-02-25 CN CN201380011342.7A patent/CN104159575B/zh not_active Expired - Fee Related
- 2013-02-25 WO PCT/FR2013/000052 patent/WO2013128088A1/fr active Application Filing
- 2013-02-25 SG SG11201405316WA patent/SG11201405316WA/en unknown
- 2013-02-25 HU HUE13715263A patent/HUE030737T2/en unknown
- 2013-02-25 EP EP13715263.3A patent/EP2819655B1/fr active Active
- 2013-02-25 PT PT137152633T patent/PT2819655T/pt unknown
- 2013-02-25 CA CA2863159A patent/CA2863159C/fr not_active Expired - Fee Related
- 2013-02-25 AU AU2013224831A patent/AU2013224831B2/en not_active Ceased
- 2013-02-25 UA UAA201409664A patent/UA113301C2/uk unknown
- 2013-02-25 KR KR1020147023180A patent/KR101897855B1/ko active IP Right Grant
- 2013-02-25 SI SI201330319A patent/SI2819655T1/sl unknown
- 2013-02-25 US US14/381,896 patent/US20150073055A1/en not_active Abandoned
- 2013-02-25 EA EA201400960A patent/EA025692B1/ru not_active IP Right Cessation
- 2013-02-25 JP JP2014559270A patent/JP6163169B2/ja not_active Expired - Fee Related
- 2013-02-25 ES ES13715263.3T patent/ES2593276T3/es active Active
- 2013-02-25 BR BR112014020626A patent/BR112014020626A2/pt not_active Application Discontinuation
- 2013-02-27 TW TW102106817A patent/TWI626042B/zh not_active IP Right Cessation
- 2013-02-27 AR ARP130100596A patent/AR090169A1/es unknown
-
2014
- 2014-08-07 IL IL234009A patent/IL234009B/en active IP Right Grant
- 2014-08-12 ZA ZA2014/05910A patent/ZA201405910B/en unknown
- 2014-08-14 PH PH12014501837A patent/PH12014501837A1/en unknown
- 2014-08-19 CL CL2014002203A patent/CL2014002203A1/es unknown
-
2016
- 2016-09-12 HR HRP20161165TT patent/HRP20161165T1/hr unknown
- 2016-10-12 SM SM201600363T patent/SMT201600363B/it unknown
- 2016-10-26 CY CY20161101079T patent/CY1118166T1/el unknown
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