HRP20151339T1 - Pripravak baziran na ubidekarenonu - Google Patents

Pripravak baziran na ubidekarenonu Download PDF

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HRP20151339T1
HRP20151339T1 HRP20151339TT HRP20151339T HRP20151339T1 HR P20151339 T1 HRP20151339 T1 HR P20151339T1 HR P20151339T T HRP20151339T T HR P20151339TT HR P20151339 T HRP20151339 T HR P20151339T HR P20151339 T1 HRP20151339 T1 HR P20151339T1
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preparation according
sucrose
coq10
class
ternary
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Tiziana Canal
Fulvio Fortuna
Elena MENCINI
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Asoltech Srl
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Publication of HRP20151339T8 publication Critical patent/HRP20151339T8/hr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15—Vitamins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07—Retinol compounds, e.g. vitamin A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/35—Ketones, e.g. benzophenone
    • A61K8/355—Quinones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60—Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
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    • A61K8/732—Starch; Amylose; Amylopectin; Derivatives thereof
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    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P17/16—Emollients or protectives, e.g. against radiation
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P3/04—Anorexiants; Antiobesity agents
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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Claims (25)

1. Ternarni pripravak baziran na ubidekarenonu, ili koenzimu Q10 ili CoQ10, naznačen time da se sastoji od tri komponente ili razreda komponenata: od CoQ10, od jednog ili više specifičnih hidrofilnih nosača odabranih iz razreda maltodekstrina i jednog ili više pomoćnih sredstava odabranih iz razreda sukroza-estera.
2. Pripravak prema zahtjevu 1, naznačen time da se u suhom stanju zajednički usitnjavaju CoQ10, jedan ili više specifičnih hidrofilnih nosača odabranih iz razreda maltodekstrina i jedno ili više pomoćnih sredstava odabranih iz razreda sukroza-estera.
3. Pripravak prema zahtjevu 1 ili 2, naznačen time da sadrži težinski postotak CoQ10 koji se nalazi između 5% i 30%.
4. Pripravak prema zahtjevu 1, 2 ili 3, naznačen time da sadrži težinski postotak CoQ10 koji se nalazi između 7.5% i 20%.
5. Pripravak prema bilo kojem prethodnom zahtjevu, naznačen time da sadrži težinski postotak CoQ10 koji se nalazi između 10% i 15%.
6. Pripravak prema bilo kojem prethodnom zahtjevu, naznačen time da sadrži težinski postotak jednog ili više pomoćnih sredstava odabranih iz razreda sukroza-estera koji se nalazi između 5% i 30%.
7. Pripravak prema bilo kojem prethodnom zahtjevu, naznačen time da sadrži težinski postotak jednog ili više pomoćnih sredstava odabranih iz razreda sukroza-estera koji se nalazi između 7.5% i 20%.
8. Pripravak prema bilo kojem prethodnom zahtjevu, naznačen time da sadrži težinski postotak jednog ili više pomoćnih sredstava odabranih iz razreda sukroza-estera koji se nalazi između 10% i 15%.
9. Pripravak prema bilo kojem prethodnom zahtjevu, naznačen time da je, s obzirom na težinski postotak CoQ10 i pomoćnog sredstva koje se zajednički usitnjava odabranog iz razreda sukroza-estera, predviđen težinski postotak hidrofilnog nosača iz razreda maltodekstrina tako da se dobije 100% težinski.
10. Pripravak prema bilo kojem prethodnom zahtjevu, naznačen time da su težinski postotci CoQ10 i sukroza-estera u pripravku prema predmetnom izumu jednaki.
11. Pripravak prema bilo kojem zahtjevu od 1 do 9, naznačen time da su težinski postotci CoQ10 i sukroza-estera u pripravku prema predmetnom izumu međusobno različiti.
12. Pripravak prema bilo kojem prethodnom zahtjevu, naznačen time da je odabrani sukroza-ester jedan ili više od saharoza monopalmitata, saharoza monostearata, saharoza dipalmitata, saharoza distearata, saharoza alhilata ili smjese dva ili više od navedenih.
13. Pripravak prema bilo kojem prethodnom zahtjevu naznačen time da je za uporabu u za terapijski farmaceutski tretman.
14. Pripravak prema bilo kojem prethodnom zahtjevu naznačen time da je za uporabu za dijetetski tretman ili za integralne dodatke prehrani.
15. Pripravak prema bilo kojem prethodnom zahtjevu naznačen time da je za uporabu za kozmetički tretman.
16. Pripravak prema bilo kojem prethodnom zahtjevu naznačen time da je za uporabu za terapijski veterinarski tretman, dijetetski tretman ili integralni dodatak prehrani.
17. Formulacija naznačena time da sadrži ternarni pripravak prema bilo kojem prethodnom zahtjevu sastavljen ili izmiješan s: - jednim ili više vitamina iz skupine vitamina B, i - jednim ili više minerala ili metala, kao što su magnezij, kalij, cink, selen, kalcij, fluor, fosfor, i - jednom ili više drugih tvari koje su odabrane iz skupine koju čine: kreatin, karnitin, gama orizanol, lipoična kiselina, kolin, karnozin, fosfatidilserin, lutein, likopen, resveratrol, drugi antioksidansi, esencijalne masne kiseline omega-3 i/ili omega-6, biljne tvari, ekstrakti i/ili pripravci, kako što su ekstrakt borovnice, Ginsenga, Ginkgo bilobe, Rhodiola rosea, Boswellia serrata, kvasac, ksilitrol, eritritol, manitol, sorbitol, amino kiseline, razgranate ili modificirane amino kiseline.
18. Formulacija prema zahtjevu 17, naznačena time da sadrži ternarni pripravak prema bilo kojem zahtjevu od 1 do 16 i: - vitamine iz skupine vitamina B, uključujući jedan ili više vitamina B1, B2, B3, B5, B6, B12, - kreatin, - Ginseng, - magnezij i - kalij.
19. Formulacija prema zahtjevu 17, naznačena time da sadrži ternarni pripravak prema bilo kojem zahtjevu od 1 do 16 i: - kolin, - L-arginin, - vitamine iz skupine vitamina B, uključujući jedan ili više vitamina B1, B2, B3, B5, B6, B12, - vitamin A, - vitamin E, - selen, - cink, - magnezij i - Ginkgo biloba.
20. Formulacija prema zahtjevu 17, naznačena time da sadrži ternarni pripravak prema bilo kojem zahtjevu od 1 do 16 i: - karnitin, - karnozin, - magnezij, - cink i kalij, - vitamine B1, B12, C i E.
21. Formulacija prema zahtjevu 17, naznačena time da sadrži ternarni pripravak prema bilo kojem zahtjevu od 1 do 16 i: - lutein, - ekstrakt borovnice, - vitamine A i B12 i - cink.
22. Formulacija prema zahtjevu 17, naznačena time da sadrži ternarni pripravak prema bilo kojem zahtjevu od 1 do 16 i: - omega-3, - vitamine A, B3, B5, C i D, H, - kalcij, - fluor, - fosfor i magnezij i - kslitol, - sa ili bez Boswellia serrata.
23. Formulacija naznačena time da sadrži ternarni pripravak prema bilo kojem zahtjevu od 1 do 16 i vitamin A.
24. Postupak za pripremanje ternarnog pripravka baziranog na ubidekarenonu, ili koenzimu Q10 ili CoQ10 prema bilo kojem od zahtjeva 1 do 16, naznačen time da predviđa korak pripremanja navedenog ternarnog pripravka pomoću miješanja, uz korištenje samo tri komponente ili razreda komponenata: CoQ10, jednog ili više specifičnih hidrofilnih nosača koji su odabrani iz razreda maltodekstrina i jednog ili više pomoćnih sredstava odabranih iz razreda sukroza-estera.
25. Postupak prema zahtjevu 24, naznačen time da predviđa podvrgavanje suhom zajedničkom usitnjavanju, poželjno njihovom istovremenom zajedničkom usitnjavanju, CoQ10, jednog ili više specifičnih hidrofilnih nosača koji su odabrani iz razreda maltodekstrina i jednog ili više pomoćnih sredstava odabranih iz razreda sukroza-estera.
HRP20151339TT 2011-12-02 2015-12-08 Composition based on ubidecarenone HRP20151339T8 (en)

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Application Number Priority Date Filing Date Title
IT000196A ITUD20110196A1 (it) 2011-12-02 2011-12-02 Composizione a base di ubidecarenone
EP12813443.4A EP2713771B1 (en) 2011-12-02 2012-12-03 Composition based on ubidecarenone
PCT/IB2012/002565 WO2013080028A1 (en) 2011-12-02 2012-12-03 Composition based on ubidecarenone

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HRP20151339T1 true HRP20151339T1 (hr) 2016-01-01
HRP20151339T8 HRP20151339T8 (en) 2016-02-26

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US (1) US9675564B2 (hr)
EP (1) EP2713771B1 (hr)
JP (1) JP5984956B2 (hr)
KR (1) KR101616853B1 (hr)
CN (1) CN104093322B (hr)
BR (1) BR112014013348A2 (hr)
CA (1) CA2857592C (hr)
DK (1) DK2713771T3 (hr)
ES (1) ES2550086T3 (hr)
HR (1) HRP20151339T8 (hr)
HU (1) HUE026130T2 (hr)
IT (1) ITUD20110196A1 (hr)
PL (1) PL2713771T3 (hr)
PT (1) PT2713771E (hr)
SI (1) SI2713771T1 (hr)
WO (1) WO2013080028A1 (hr)

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WO2016074800A1 (en) * 2014-11-14 2016-05-19 Asoltech S.R.L. Composition based on coq10
IT202000018970A1 (it) 2020-08-03 2022-02-03 Asoltech Srl Composizione a base di mirra

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JP2015505826A (ja) 2015-02-26
CA2857592A1 (en) 2013-06-06
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WO2013080028A1 (en) 2013-06-06
ES2550086T3 (es) 2015-11-04
CN104093322A (zh) 2014-10-08
US9675564B2 (en) 2017-06-13
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ITUD20110196A1 (it) 2013-06-03
EP2713771A1 (en) 2014-04-09
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DK2713771T3 (en) 2015-12-14
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EP2713771B1 (en) 2015-09-16
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CA2857592C (en) 2018-06-05
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