HRP20131103T1 - Benzimidazoli i njihovi farmaceutski pripravci - Google Patents

Benzimidazoli i njihovi farmaceutski pripravci Download PDF

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Publication number
HRP20131103T1
HRP20131103T1 HRP20131103AT HRP20131103T HRP20131103T1 HR P20131103 T1 HRP20131103 T1 HR P20131103T1 HR P20131103A T HRP20131103A T HR P20131103AT HR P20131103 T HRP20131103 T HR P20131103T HR P20131103 T1 HRP20131103 T1 HR P20131103T1
Authority
HR
Croatia
Prior art keywords
image
aryl
cycloalkyl
alkyl
heterocyclic
Prior art date
Application number
HRP20131103AT
Other languages
English (en)
Croatian (hr)
Inventor
Iwao Ojima
Seung-Yub Lee
Original Assignee
The Research Foundation Of State University Of New York
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Research Foundation Of State University Of New York filed Critical The Research Foundation Of State University Of New York
Publication of HRP20131103T1 publication Critical patent/HRP20131103T1/hr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/18—Benzimidazoles; Hydrogenated benzimidazoles with aryl radicals directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/08—Antibacterial agents for leprosy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/08—Radicals containing only hydrogen and carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HRP20131103AT 2007-04-20 2008-04-21 Benzimidazoli i njihovi farmaceutski pripravci HRP20131103T1 (hr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US91298007P 2007-04-20 2007-04-20
PCT/US2008/005084 WO2008130669A1 (en) 2007-04-20 2008-04-21 Benzimidazoles and pharmaceutical compositions thereof

Publications (1)

Publication Number Publication Date
HRP20131103T1 true HRP20131103T1 (hr) 2013-12-20

Family

ID=39875833

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20131103AT HRP20131103T1 (hr) 2007-04-20 2008-04-21 Benzimidazoli i njihovi farmaceutski pripravci

Country Status (17)

Country Link
US (1) US8232410B2 (cg-RX-API-DMAC7.html)
EP (1) EP2154966B1 (cg-RX-API-DMAC7.html)
JP (1) JP5400032B2 (cg-RX-API-DMAC7.html)
CN (1) CN101677553A (cg-RX-API-DMAC7.html)
AU (1) AU2008242488B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0810244A2 (cg-RX-API-DMAC7.html)
CA (1) CA2684594C (cg-RX-API-DMAC7.html)
DK (1) DK2154966T3 (cg-RX-API-DMAC7.html)
EA (1) EA016726B1 (cg-RX-API-DMAC7.html)
ES (1) ES2434693T3 (cg-RX-API-DMAC7.html)
HR (1) HRP20131103T1 (cg-RX-API-DMAC7.html)
IN (1) IN2009KN03959A (cg-RX-API-DMAC7.html)
MX (1) MX2009011281A (cg-RX-API-DMAC7.html)
PL (1) PL2154966T3 (cg-RX-API-DMAC7.html)
PT (1) PT2154966E (cg-RX-API-DMAC7.html)
SI (1) SI2154966T1 (cg-RX-API-DMAC7.html)
WO (1) WO2008130669A1 (cg-RX-API-DMAC7.html)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8232310B2 (en) 2006-12-29 2012-07-31 Georgetown University Targeting of EWS-FLI1 as anti-tumor therapy
US8039502B2 (en) 2007-07-24 2011-10-18 The Ohio State University Research Foundation Anti-infective agents against intracellular pathogens
US20120108823A1 (en) * 2009-04-22 2012-05-03 The Ohio State University Research Foundation Anti-francisella agents
EP2475428B1 (en) * 2009-09-11 2015-07-01 Probiodrug AG Heterocylcic derivatives as inhibitors of glutaminyl cyclase
WO2013116823A1 (en) * 2012-02-02 2013-08-08 The Research Foundation Of State University Of New York Benzimidazoles and uses thereof
WO2013142326A1 (en) * 2012-03-23 2013-09-26 The Research Foundation Of State University Of New York 5-carbonylamino-/(sulfonamido-) substituted benz imidazoles and use thereof treatment of tuberculosis
MX377618B (es) * 2012-04-12 2025-03-07 Univ Georgetown Métodos y composiciones para el tratamiento de la familia de tumores del sarcoma de ewing.
CN103333170B (zh) * 2013-06-14 2016-08-10 清华大学 苯并咪唑类化合物及其用途
JP6389884B2 (ja) 2013-10-24 2018-09-12 ジョージタウン・ユニバーシティＧｅｏｒｇｅｔｏｗｎ Ｕｎｉｖｅｒｓｉｔｙ 癌を治療するための方法及び組成物
CN106061951A (zh) * 2013-11-22 2016-10-26 纽约州立大学研究基金会 苯并咪唑及其在结核病治疗中的用途
WO2015138611A2 (en) 2014-03-11 2015-09-17 Colorado State University Research Foundation Methods for improved in vitro-in vivo efficacy determination
WO2015193506A1 (en) * 2014-06-20 2015-12-23 Institut Pasteur Korea Anti-infective compounds
EP3204376B1 (en) 2014-10-09 2023-04-19 Oncternal Therapeutics, Inc. Indolinone compounds and uses thereof
US9822122B2 (en) 2016-03-31 2017-11-21 Oncternal Therapeutics, Inc. Indoline analogs and uses thereof
MX395539B (es) 2016-07-29 2025-03-25 Oncternal Therapeutics Inc Usos de compuestos de indolinona
CN111303092B (zh) * 2020-04-07 2021-05-25 山东昌邑灶户盐化有限公司 2,4-二硝基-6-氯苯胺衍生物、合成方法及其应用
JP2024529298A (ja) 2021-07-09 2024-08-06 プレキシウム インコーポレイテッド Ｉｋｚｆ２を調節するアリール化合物及び医薬組成物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61170732A (ja) * 1985-01-25 1986-08-01 Fuji Photo Film Co Ltd ハロゲン化銀写真感光材料
US7405235B2 (en) * 2001-05-04 2008-07-29 Paratek Pharmaceuticals, Inc. Transcription factor modulating compounds and methods of use thereof
EP1805147B1 (en) * 2004-09-30 2014-08-13 Janssen Pharmaceutica NV Novel benzimidazole derivatives useful as selective androgen receptor modulators (sarms)
BRPI0621509A2 (pt) 2006-03-15 2011-12-13 Csir modulação da atividade de fosforil transferase de glutamina sintetase

Also Published As

Publication number Publication date
JP2010524947A (ja) 2010-07-22
PT2154966E (pt) 2013-11-13
EA200901423A1 (ru) 2010-06-30
US20100256203A1 (en) 2010-10-07
US8232410B2 (en) 2012-07-31
BRPI0810244A2 (pt) 2014-09-30
EP2154966A1 (en) 2010-02-24
EP2154966A4 (en) 2010-12-15
EP2154966B1 (en) 2013-08-21
JP5400032B2 (ja) 2014-01-29
AU2008242488A1 (en) 2008-10-30
MX2009011281A (es) 2010-03-08
CA2684594C (en) 2015-10-06
IN2009KN03959A (cg-RX-API-DMAC7.html) 2015-08-28
ES2434693T3 (es) 2013-12-17
WO2008130669A1 (en) 2008-10-30
SI2154966T1 (sl) 2014-02-28
AU2008242488B2 (en) 2014-10-30
DK2154966T3 (da) 2013-11-18
PL2154966T3 (pl) 2014-03-31
CN101677553A (zh) 2010-03-24
EA016726B1 (ru) 2012-07-30
CA2684594A1 (en) 2008-10-30

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