HRP20090632T1 - Novi derivati naftalena, postupak za njihovu pripravu i farmaceutski pripravci koji ih sadrže - Google Patents
Novi derivati naftalena, postupak za njihovu pripravu i farmaceutski pripravci koji ih sadrže Download PDFInfo
- Publication number
- HRP20090632T1 HRP20090632T1 HR20090632T HRP20090632T HRP20090632T1 HR P20090632 T1 HRP20090632 T1 HR P20090632T1 HR 20090632 T HR20090632 T HR 20090632T HR P20090632 T HRP20090632 T HR P20090632T HR P20090632 T1 HRP20090632 T1 HR P20090632T1
- Authority
- HR
- Croatia
- Prior art keywords
- compound
- formula
- pharmaceutically acceptable
- disorders
- accordance
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims 2
- 150000002790 naphthalenes Chemical class 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 claims abstract 13
- 150000003839 salts Chemical class 0.000 claims abstract 6
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 claims abstract 3
- HEPRAZQZDVDTHU-UHFFFAOYSA-N N-[3-hydroxy-2-(7-methoxy-1-naphthyl)propyl]propionamide Chemical compound C1=C(OC)C=C2C(C(CO)CNC(=O)CC)=CC=CC2=C1 HEPRAZQZDVDTHU-UHFFFAOYSA-N 0.000 claims abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 4
- 208000035475 disorder Diseases 0.000 claims 4
- 239000000825 pharmaceutical preparation Substances 0.000 claims 3
- 208000024827 Alzheimer disease Diseases 0.000 claims 2
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 229940079593 drug Drugs 0.000 claims 2
- 206010022437 insomnia Diseases 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 230000007170 pathology Effects 0.000 claims 2
- 238000000926 separation method Methods 0.000 claims 2
- 208000000044 Amnesia Diseases 0.000 claims 1
- 208000019901 Anxiety disease Diseases 0.000 claims 1
- 208000020401 Depressive disease Diseases 0.000 claims 1
- 208000026139 Memory disease Diseases 0.000 claims 1
- 208000019695 Migraine disease Diseases 0.000 claims 1
- HEPRAZQZDVDTHU-ZDUSSCGKSA-N N-[(2S)-3-hydroxy-2-(7-methoxy-1-naphthyl)propyl]propionamide Chemical compound C1=C(OC)C=C2C([C@H](CO)CNC(=O)CC)=CC=CC2=C1 HEPRAZQZDVDTHU-ZDUSSCGKSA-N 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 208000008589 Obesity Diseases 0.000 claims 1
- 206010033664 Panic attack Diseases 0.000 claims 1
- 208000018737 Parkinson disease Diseases 0.000 claims 1
- 208000028017 Psychotic disease Diseases 0.000 claims 1
- 206010039966 Senile dementia Diseases 0.000 claims 1
- 201000001880 Sexual dysfunction Diseases 0.000 claims 1
- 230000032683 aging Effects 0.000 claims 1
- 230000036506 anxiety Effects 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 230000002490 cerebral effect Effects 0.000 claims 1
- 206010012601 diabetes mellitus Diseases 0.000 claims 1
- 210000002249 digestive system Anatomy 0.000 claims 1
- IEJIGPNLZYLLBP-UHFFFAOYSA-N dimethyl carbonate Chemical compound COC(=O)OC IEJIGPNLZYLLBP-UHFFFAOYSA-N 0.000 claims 1
- ATUOYWHBWRKTHZ-UHFFFAOYSA-N dimethylmethane Natural products CCC ATUOYWHBWRKTHZ-UHFFFAOYSA-N 0.000 claims 1
- 230000002526 effect on cardiovascular system Effects 0.000 claims 1
- 206010015037 epilepsy Diseases 0.000 claims 1
- 230000010006 flight Effects 0.000 claims 1
- 150000004678 hydrides Chemical class 0.000 claims 1
- 239000002955 immunomodulating agent Substances 0.000 claims 1
- 229940121354 immunomodulator Drugs 0.000 claims 1
- 208000024714 major depressive disease Diseases 0.000 claims 1
- 201000003995 melancholia Diseases 0.000 claims 1
- 230000006984 memory degeneration Effects 0.000 claims 1
- 208000023060 memory loss Diseases 0.000 claims 1
- 206010027599 migraine Diseases 0.000 claims 1
- 235000020824 obesity Nutrition 0.000 claims 1
- 230000016087 ovulation Effects 0.000 claims 1
- 208000019906 panic disease Diseases 0.000 claims 1
- 230000001575 pathological effect Effects 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 238000002360 preparation method Methods 0.000 claims 1
- 239000001294 propane Substances 0.000 claims 1
- -1 propane amide Chemical class 0.000 claims 1
- RZWZRACFZGVKFM-UHFFFAOYSA-N propanoyl chloride Chemical compound CCC(Cl)=O RZWZRACFZGVKFM-UHFFFAOYSA-N 0.000 claims 1
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 claims 1
- 201000000980 schizophrenia Diseases 0.000 claims 1
- 208000012672 seasonal affective disease Diseases 0.000 claims 1
- 231100000872 sexual dysfunction Toxicity 0.000 claims 1
- 208000019116 sleep disease Diseases 0.000 claims 1
- 230000035882 stress Effects 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/17—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/18—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
- C07C233/04—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Immunology (AREA)
- Reproductive Health (AREA)
- Pain & Pain Management (AREA)
- Gynecology & Obstetrics (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Emergency Medicine (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Anesthesiology (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Child & Adolescent Psychology (AREA)
- Epidemiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0605917A FR2903102B1 (fr) | 2006-06-30 | 2006-06-30 | Nouveaux derives naphtaleniques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20090632T1 true HRP20090632T1 (hr) | 2010-01-31 |
Family
ID=37906940
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20090632T HRP20090632T1 (hr) | 2006-06-30 | 2009-11-27 | Novi derivati naftalena, postupak za njihovu pripravu i farmaceutski pripravci koji ih sadrže |
Country Status (33)
| Country | Link |
|---|---|
| US (1) | US7462741B2 (el) |
| EP (1) | EP1873140B1 (el) |
| JP (1) | JP4675938B2 (el) |
| KR (1) | KR100912163B1 (el) |
| CN (1) | CN101096346B (el) |
| AR (1) | AR061740A1 (el) |
| AT (1) | ATE444278T1 (el) |
| AU (1) | AU2007203044A1 (el) |
| BR (1) | BRPI0702817A (el) |
| CA (1) | CA2593621C (el) |
| CY (1) | CY1109663T1 (el) |
| DE (1) | DE602007002591D1 (el) |
| DK (1) | DK1873140T3 (el) |
| EA (1) | EA012283B1 (el) |
| ES (1) | ES2334278T3 (el) |
| FR (1) | FR2903102B1 (el) |
| GE (1) | GEP20094745B (el) |
| HK (1) | HK1111403A1 (el) |
| HR (1) | HRP20090632T1 (el) |
| MA (1) | MA29223B1 (el) |
| MX (1) | MX2007007899A (el) |
| MY (1) | MY142817A (el) |
| NO (1) | NO20073295L (el) |
| NZ (1) | NZ556188A (el) |
| PL (1) | PL1873140T3 (el) |
| PT (1) | PT1873140E (el) |
| RS (1) | RS51079B (el) |
| SG (1) | SG138589A1 (el) |
| SI (1) | SI1873140T1 (el) |
| TW (1) | TWI326679B (el) |
| UA (1) | UA93190C2 (el) |
| WO (1) | WO2008000968A1 (el) |
| ZA (1) | ZA200704955B (el) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2903101B1 (fr) * | 2006-06-30 | 2008-09-26 | Servier Lab | Nouveaux derives naphtaleniques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| EP2921473B1 (en) * | 2012-10-09 | 2017-09-27 | Jiangxi Synergy Pharmaceutical Co. Ltd. | 1-cyan-1-(7-methoxyl-1-naphtyl) methanol ester compound and preparation method and use thereof |
| CN102875408B (zh) * | 2012-10-09 | 2014-07-16 | 江西同和药业有限责任公司 | 一种阿戈美拉汀的制备方法 |
| CN102875415B (zh) * | 2012-10-09 | 2014-08-20 | 江西同和药业有限责任公司 | 一种化合物及其制备方法和应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2689124A1 (fr) * | 1992-03-27 | 1993-10-01 | Adir | Nouvelles naphtylalkylamines, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent. |
| FR2737725B1 (fr) * | 1995-08-08 | 1997-10-31 | Valentonine | Nouveaux derives acyles de la melatonine et d'analogues melatoninergiques, leur procede de preparation et leur utilisation en tant que medicament |
| FR2771739B1 (fr) * | 1997-11-28 | 2001-04-20 | Adir | Nouveaux composes naphtaleniques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| FR2784375B1 (fr) * | 1998-10-12 | 2000-11-24 | Adir | Nouveaux derives cycliques a chaine cycloalkylenique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| FR2805993B1 (fr) * | 2000-03-08 | 2004-01-16 | Adir | Utilisation de ligands melatoninergiques pour l'obtention de compositions pharmaceutiques destinees a la prevention ou au traitement du developpement de la tolerance aux composes nitres |
| FR2903101B1 (fr) * | 2006-06-30 | 2008-09-26 | Servier Lab | Nouveaux derives naphtaleniques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
-
2006
- 2006-06-30 FR FR0605917A patent/FR2903102B1/fr not_active Expired - Fee Related
-
2007
- 2007-06-14 MY MYPI20070960A patent/MY142817A/en unknown
- 2007-06-18 MA MA30015A patent/MA29223B1/fr unknown
- 2007-06-26 SG SG200704785-5A patent/SG138589A1/en unknown
- 2007-06-26 ZA ZA200704955A patent/ZA200704955B/xx unknown
- 2007-06-27 UA UAA200707268A patent/UA93190C2/ru unknown
- 2007-06-27 MX MX2007007899A patent/MX2007007899A/es active IP Right Grant
- 2007-06-28 US US11/823,771 patent/US7462741B2/en not_active Expired - Fee Related
- 2007-06-28 NZ NZ556188A patent/NZ556188A/en not_active IP Right Cessation
- 2007-06-28 KR KR1020070064103A patent/KR100912163B1/ko not_active IP Right Cessation
- 2007-06-28 NO NO20073295A patent/NO20073295L/no not_active Application Discontinuation
- 2007-06-29 ES ES07290819T patent/ES2334278T3/es active Active
- 2007-06-29 DE DE602007002591T patent/DE602007002591D1/de active Active
- 2007-06-29 EP EP07290819A patent/EP1873140B1/fr active Active
- 2007-06-29 SI SI200730089T patent/SI1873140T1/sl unknown
- 2007-06-29 JP JP2007171622A patent/JP4675938B2/ja not_active Expired - Fee Related
- 2007-06-29 CA CA2593621A patent/CA2593621C/fr not_active Expired - Fee Related
- 2007-06-29 RS RSP-2009/0502A patent/RS51079B/sr unknown
- 2007-06-29 PT PT07290819T patent/PT1873140E/pt unknown
- 2007-06-29 GE GEAP200710154A patent/GEP20094745B/en unknown
- 2007-06-29 AT AT07290819T patent/ATE444278T1/de active
- 2007-06-29 WO PCT/FR2007/001105 patent/WO2008000968A1/fr active Application Filing
- 2007-06-29 PL PL07290819T patent/PL1873140T3/pl unknown
- 2007-06-29 EA EA200701178A patent/EA012283B1/ru not_active IP Right Cessation
- 2007-06-29 TW TW096123645A patent/TWI326679B/zh not_active IP Right Cessation
- 2007-06-29 AU AU2007203044A patent/AU2007203044A1/en not_active Abandoned
- 2007-06-29 BR BRPI0702817-2A patent/BRPI0702817A/pt not_active IP Right Cessation
- 2007-06-29 AR ARP070102912A patent/AR061740A1/es unknown
- 2007-06-29 CN CN2007101362902A patent/CN101096346B/zh not_active Expired - Fee Related
- 2007-06-29 DK DK07290819T patent/DK1873140T3/da active
-
2008
- 2008-02-21 HK HK08101883.0A patent/HK1111403A1/xx unknown
-
2009
- 2009-11-27 HR HR20090632T patent/HRP20090632T1/hr unknown
- 2009-12-16 CY CY20091101309T patent/CY1109663T1/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HRP20170095T1 (hr) | Novi kristalni oblik iii agomelatina, postupak za njegovu pripravu i farmaceutski pripravci istog | |
| HRP20161672T1 (hr) | Novi kristalni oblik vi agomelatina, postupak priprave i farmaceutski pripravci istog | |
| CN102164488B (zh) | 有益于治疗中枢神经系统疾病和病症的新化合物 | |
| JP5460613B2 (ja) | 高純度を有する２−［４−（３−または２−フルオロベンジルオキシ）ベンジルアミノ］プロパンアミドの製造方法 | |
| HRP20161647T1 (hr) | Novi sukristali agomelatina | |
| AU2015242954B2 (en) | Inhibitors of cognitive decline | |
| US5591775A (en) | Trisubstituted naphthylalkylamides for disorders of the melatoninergic system | |
| NO336967B1 (no) | Ny krystallinsk form v av agomelatin, fremgangsmåte for dens fremstilling og farmasøytiske sammensetninger inneholdende den | |
| JPH09510188A (ja) | １−アミノインダン及びこれらの組成物 | |
| CN102482203B (zh) | 碳环glyt1受体拮抗剂 | |
| HRP20090632T1 (hr) | Novi derivati naftalena, postupak za njihovu pripravu i farmaceutski pripravci koji ih sadrže | |
| CN102850317A (zh) | 一种取代桂皮酰胺衍生物、制备方法及其应用 | |
| CN105189450A (zh) | 氨基甲酸苯酯化合物及包含该化合物的用于预防或治疗精神障碍的组合物 | |
| US9212155B2 (en) | Compounds advantageous in the treatment of central nervous system diseases and disorders | |
| Guan et al. | N-palmitoylethanolamide derivatives: synthesis and studies on anticonvulsant and antidepressant activities | |
| AU2012212219B2 (en) | Isolated compounds from turmeric oil and methods of use | |
| CN104710327B (zh) | 有益于治疗中枢神经系统疾病和病症的化合物 | |
| HRP20180019T1 (hr) | Stabilizirani amorfni oblik agomelatina, postupak za njegovu pripremu i farmaceutski pripravci koji ga sadržavaju | |
| JP2021073171A (ja) | （ｒ）−ジミラセタム（１）と（ｓ）−ジミラセタム（２）を非ラセミ比で含む相乗的組成物 | |
| RU2010120847A (ru) | Соединения индолина, фармацевтическая композиция на их основе и способ лечения или профилактики мелатонинергических заболеваний | |
| CN102816079B (zh) | 阿戈美拉汀的新共晶、它们的制备方法和含有它们的药物组合物 | |
| RU2012101227A (ru) | 1-(2-алкил-2,3-дигидро-бензофуран-4-ил)-пирролидин-3-иламинацильные соединения, фармацевтическая композиция и лекарственное средство на их основе и способ лечения или предупреждения мелатонергетических нарушений с их помощью | |
| US10793515B2 (en) | Compounds advantageous in the treatment of central nervous system diseases and disorders | |
| RU2479572C2 (ru) | Получение и применение производных фенилциклобутиламида и их стереоизомеров | |
| JPWO2020131918A5 (el) |