HRP20060089B1 - Method for the stabilization of atorvastatin - Google Patents

Method for the stabilization of atorvastatin

Info

Publication number
HRP20060089B1
HRP20060089B1 HR20060089A HRP20060089A HRP20060089B1 HR P20060089 B1 HRP20060089 B1 HR P20060089B1 HR 20060089 A HR20060089 A HR 20060089A HR P20060089 A HRP20060089 A HR P20060089A HR P20060089 B1 HRP20060089 B1 HR P20060089B1
Authority
HR
Croatia
Prior art keywords
kpa
stabilization
preferably less
partial pressure
gaseous mixture
Prior art date
Application number
HR20060089A
Other languages
English (en)
Croatian (hr)
Inventor
Sebek Pavel
Prokopova Alena
Svoboda Eduard
Radl Stanislav
Stach Jan
Sbovoda Martin
Kovacik Andrej
Danko Adrian
Petro Roman
Strizinec Miroslav
Original Assignee
Zentiva
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34117186&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HRP20060089(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from CZ20032135A external-priority patent/CZ295027B6/cs
Priority claimed from CZ20040857A external-priority patent/CZ296181B6/cs
Application filed by Zentiva filed Critical Zentiva
Publication of HRP20060089A2 publication Critical patent/HRP20060089A2/hr
Publication of HRP20060089B1 publication Critical patent/HRP20060089B1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
HR20060089A 2003-08-05 2006-03-02 Method for the stabilization of atorvastatin HRP20060089B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CZ20032135A CZ295027B6 (cs) 2003-08-05 2003-08-05 Způsob stabilizace farmaceutické kompozice
CZ20040857A CZ296181B6 (cs) 2004-08-03 2004-08-03 Zpusob stabilizace farmaceutické úcinné tuhé látky atorvastatinu
PCT/CZ2004/000045 WO2005011638A2 (en) 2003-08-05 2004-08-05 Methods for the stabilization of atorvastatin

Publications (2)

Publication Number Publication Date
HRP20060089A2 HRP20060089A2 (en) 2006-05-31
HRP20060089B1 true HRP20060089B1 (en) 2008-05-31

Family

ID=34117186

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20060089A HRP20060089B1 (en) 2003-08-05 2006-03-02 Method for the stabilization of atorvastatin

Country Status (13)

Country Link
US (1) US20080171784A1 (de)
EP (1) EP1653930B1 (de)
AT (1) ATE381322T1 (de)
CA (1) CA2535225A1 (de)
DE (1) DE602004010817T2 (de)
EA (1) EA007345B1 (de)
ES (1) ES2298763T3 (de)
HR (1) HRP20060089B1 (de)
PL (2) PL379195A1 (de)
PT (1) PT1653930E (de)
RS (1) RS20060081A (de)
SK (1) SK50462005A3 (de)
WO (1) WO2005011638A2 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101124230A (zh) * 2004-09-28 2008-02-13 特瓦制药工业有限公司 制备基本无杂质的阿托伐他汀钙形式的方法
TWI318571B (en) * 2005-06-10 2009-12-21 Lilly Co Eli Formulation of a thienopyridine platelet aggregation inhibitor
EP1741427A1 (de) * 2005-07-06 2007-01-10 KRKA, D.D., Novo Mesto Pharmazeutische Zusammensetzung enthaltend Simvastatin und Ezetimibe
CA2547216A1 (en) 2005-09-21 2007-03-21 Renuka D. Reddy Process for annealing amorphous atorvastatin
EP1810667A1 (de) 2006-01-20 2007-07-25 KRKA, tovarna zdravil, d.d., Novo mesto Pharmazeutische Zusammensetzung enthaltend amorphes Atorvastatin
CZ300047B6 (cs) * 2007-03-02 2009-01-21 Zentiva, A. S. Farmaceutická kompozice s obsahem úcinné látky atorvastatinu
EP2127628A1 (de) 2008-05-27 2009-12-02 Ranbaxy Laboratories Limited Einheitsdosenverpackung
TR200806300A2 (tr) * 2008-08-22 2010-03-22 B�Lg�� Mahmut Çözünürlük artırıcı farmasötlk formulasyon
KR20120128599A (ko) 2009-12-25 2012-11-27 사와이세이야쿠 가부시키가이샤 아트로바스타틴 함유 피복 제제
ES2589460T3 (es) 2011-12-08 2016-11-14 Hexal Ag Nueva composición farmacéutica de estatina
TWI636783B (zh) * 2012-04-18 2018-10-01 友霖生技醫藥股份有限公司 含匹伐他汀（ｐｉｔａｖａｓｔａｔｉｎ）穩定配方的醫藥組合物
CA2902343C (en) 2013-03-14 2022-08-02 Becton Dickinson France S.A.S. Injectable morphine formulations
EP2968729B1 (de) 2013-03-14 2018-08-15 Fresenius Kabi Deutschland GmbH Verpackungssystem für sauerstoffempfindliche medikamenten
EP3184103A1 (de) 2015-12-21 2017-06-28 Hexal AG Pharmazeutische zusammensetzung mit atorvastatin oder einem salz davon
EP3272336A1 (de) 2016-07-19 2018-01-24 Stada Arzneimittel Ag Atorvastatin-zusammensetzung

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001093859A1 (en) * 2000-06-09 2001-12-13 Lek Pharmaceuticals D.D. Stable pharmaceutical product and formulation
US20030042166A1 (en) * 2001-03-16 2003-03-06 Waterman Kenneth C. Pharmaceutical kit for oxygen-sensitive drugs
WO2004032920A1 (en) * 2002-10-11 2004-04-22 Lek Pharmaceuticals D.D. Stabilized pharmaceutical preparation comprising an amorphous active substance

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5180589A (en) * 1988-03-31 1993-01-19 E. R. Squibb & Sons, Inc. Pravastatin pharmaceuatical compositions having good stability
WO1994016693A1 (en) * 1993-01-19 1994-08-04 Warner-Lambert Company Stable oral ci-981 formulation and process of preparing same
EP1241110A1 (de) * 2001-03-16 2002-09-18 Pfizer Products Inc. Ausgabeeinheit für sauerstoff-empfindlichen Medikamenten
EP1336405A1 (de) * 2002-02-14 2003-08-20 Ranbaxy Laboratories, Ltd. Atorvastatin Zubereitungen stabilisiert mit Alkalimetalladditionen

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001093859A1 (en) * 2000-06-09 2001-12-13 Lek Pharmaceuticals D.D. Stable pharmaceutical product and formulation
US20030042166A1 (en) * 2001-03-16 2003-03-06 Waterman Kenneth C. Pharmaceutical kit for oxygen-sensitive drugs
WO2004032920A1 (en) * 2002-10-11 2004-04-22 Lek Pharmaceuticals D.D. Stabilized pharmaceutical preparation comprising an amorphous active substance

Also Published As

Publication number Publication date
SK50462005A3 (sk) 2005-09-08
DE602004010817T2 (de) 2008-12-11
PL1653930T3 (pl) 2008-06-30
WO2005011638A3 (en) 2005-10-20
RS20060081A (en) 2008-06-05
EP1653930A2 (de) 2006-05-10
PL379195A1 (pl) 2006-07-24
EP1653930B1 (de) 2007-12-19
ATE381322T1 (de) 2008-01-15
PT1653930E (pt) 2008-03-12
EA007345B1 (ru) 2006-08-25
ES2298763T3 (es) 2008-05-16
CA2535225A1 (en) 2005-02-10
US20080171784A1 (en) 2008-07-17
EA200500819A1 (ru) 2006-02-24
HRP20060089A2 (en) 2006-05-31
WO2005011638A2 (en) 2005-02-10
DE602004010817D1 (de) 2008-01-31

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