HRP20040691A2 - 2'-halo-3',5'-dialkoxyphen-1'-yl-imino-2-imidazolidine and the use thereof as a drug - Google Patents

2'-halo-3',5'-dialkoxyphen-1'-yl-imino-2-imidazolidine and the use thereof as a drug

Info

Publication number
HRP20040691A2
HRP20040691A2 HRP20040691A HRP20040691A2 HR P20040691 A2 HRP20040691 A2 HR P20040691A2 HR P20040691 A HRP20040691 A HR P20040691A HR P20040691 A2 HRP20040691 A2 HR P20040691A2
Authority
HR
Croatia
Prior art keywords
dialkoxyphen
imidazolidine
imino
halo
drug
Prior art date
Application number
Other languages
English (en)
Inventor
Franz Esser
Pascale Pouzet
Naoki Ishhiguro
Hisato Kitagawa
Ikunobu Muramatsu
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of HRP20040691A2 publication Critical patent/HRP20040691A2/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44Nitrogen atoms not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44Nitrogen atoms not forming part of a nitro radical
    • C07D233/50Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)
HRP20040691 2002-01-31 2004-07-29 2'-halo-3',5'-dialkoxyphen-1'-yl-imino-2-imidazolidine and the use thereof as a drug HRP20040691A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02002352A EP1333028A1 (en) 2002-01-31 2002-01-31 2'-Halo-3',5'-dialkoxyphen-1'-yl-imino-2-imidazolidine derivatives and the use thereof for the treatment of urinary incontinence
PCT/EP2002/014299 WO2003064398A1 (en) 2002-01-31 2002-12-16 2'-halo-3',5'-dialkoxyphen-1'-yl-imino-2-imidazolidine derivatives and the use thereof for the treatment of urinary incontinence

Publications (1)

Publication Number Publication Date
HRP20040691A2 true HRP20040691A2 (en) 2004-12-31

Family

ID=8185397

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20040691 HRP20040691A2 (en) 2002-01-31 2004-07-29 2'-halo-3',5'-dialkoxyphen-1'-yl-imino-2-imidazolidine and the use thereof as a drug

Country Status (20)

Country Link
EP (2) EP1333028A1 (xx)
JP (1) JP2005516066A (xx)
KR (1) KR20040074134A (xx)
CN (1) CN1617857A (xx)
AR (1) AR038380A1 (xx)
BR (1) BR0215560A (xx)
CA (1) CA2474588A1 (xx)
EA (1) EA200400877A1 (xx)
EC (1) ECSP045210A (xx)
HR (1) HRP20040691A2 (xx)
HU (1) HUP0402654A2 (xx)
IL (1) IL162776A0 (xx)
MX (1) MXPA04007250A (xx)
NO (1) NO20043614L (xx)
PE (1) PE20030819A1 (xx)
PL (1) PL369826A1 (xx)
TW (1) TW200418462A (xx)
UY (1) UY27628A1 (xx)
WO (1) WO2003064398A1 (xx)
ZA (1) ZA200405173B (xx)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4168086B1 (ja) * 2008-04-16 2008-10-22 国立大学法人福井大学 イミダゾリン誘導体
US20090286829A1 (en) * 2008-05-13 2009-11-19 Allergan, Inc. Quinolynylmethylimidizoles as therapeutic agents
US8258167B2 (en) 2008-05-13 2012-09-04 Allergan, Inc Naphthylmethylimidizoles as therapeutic agents
US8063231B2 (en) * 2008-06-09 2011-11-22 Allergan, Inc. Methods of treating alpha adrenergic mediated conditions
EP2303264B1 (en) * 2008-06-09 2018-04-04 Allergan, Inc. Methods of treating alpha adrenergic mediated conditions using imidazoline derivatives
US9034910B2 (en) 2008-06-09 2015-05-19 Allergan, Inc. Methods of treating alpha adrenergic mediated conditions

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2220906A1 (de) * 1972-04-28 1973-11-15 Boehringer Sohn Ingelheim Neue substituierte 2-phenylaminoimidazoline-(2), deren saeureadditionssalze sowie verfahren zu deren herstellung
DE2259160A1 (de) * 1972-12-02 1974-06-06 Boehringer Sohn Ingelheim Neue substituierte 2-phenylaminoimidazoline, deren saeureadditionssalze und verfahren zur herstellung derselben sowie ihre verwendung als arzneimittel
AT333749B (de) * 1974-07-03 1976-12-10 Chemie Linz Ag Verfahren zur herstellung von neuen 2-arylamino-2-imidazolinderivaten
MTP837B (en) * 1977-11-07 1979-10-22 Hoffman La Roche And Co Aktien Derivatives 2 finino-imidazolidire
DE3514351A1 (de) * 1985-04-20 1986-11-06 Boehringer Ingelheim KG, 6507 Ingelheim Neue substituierte 2-(n-alkinyl-n-phenyl)amino)-imidazolinderivate, deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zu deren herstellung
DE19514579A1 (de) * 1995-04-20 1996-10-24 Boehringer Ingelheim Kg Verwendung von alpha¶1¶¶L¶-Agonisten zur Behandlung der Harninkontinenz
SG72827A1 (en) * 1997-06-23 2000-05-23 Hoffmann La Roche Phenyl-and aminophenyl-alkylsulfonamide and urea derivatives
DE19740176C2 (de) * 1997-09-12 2000-04-06 Lemfoerder Metallwaren Ag Handschaltvorrichtung für ein Kraftfahrzeug

Also Published As

Publication number Publication date
IL162776A0 (en) 2005-11-20
EP1472231A1 (en) 2004-11-03
PL369826A1 (en) 2005-05-02
KR20040074134A (ko) 2004-08-21
JP2005516066A (ja) 2005-06-02
NO20043614L (no) 2004-08-30
EP1333028A1 (en) 2003-08-06
CA2474588A1 (en) 2003-08-07
ZA200405173B (en) 2005-06-21
BR0215560A (pt) 2004-12-21
EA200400877A1 (ru) 2005-02-24
TW200418462A (en) 2004-10-01
UY27628A1 (es) 2003-08-29
ECSP045210A (es) 2004-09-28
CN1617857A (zh) 2005-05-18
AR038380A1 (es) 2005-01-12
HUP0402654A2 (hu) 2005-03-29
MXPA04007250A (es) 2004-10-29
WO2003064398A1 (en) 2003-08-07
PE20030819A1 (es) 2003-10-20

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Legal Events

Date Code Title Description
A1OB Publication of a patent application
OBST Application withdrawn