BR0215560A - Derivados de 2'-halo-3',5'-dialcoxifen-1'-il-imino-2-imidazolidina e o seu uso para o tratamento de incontinência urinária - Google Patents

Derivados de 2'-halo-3',5'-dialcoxifen-1'-il-imino-2-imidazolidina e o seu uso para o tratamento de incontinência urinária

Info

Publication number
BR0215560A
BR0215560A BR0215560-5A BR0215560A BR0215560A BR 0215560 A BR0215560 A BR 0215560A BR 0215560 A BR0215560 A BR 0215560A BR 0215560 A BR0215560 A BR 0215560A
Authority
BR
Brazil
Prior art keywords
halo
imino
treatment
urinary incontinence
dialkoxyphen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
BR0215560-5A
Other languages
English (en)
Inventor
Franz Esser
Pascale Pouzet
Naoki Ishiguro
Hisato Kitagawa
Ikunobu Muramatsu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH Co KG
Original Assignee
Boehringer Ingelheim Pharma GmbH Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma GmbH Co KG filed Critical Boehringer Ingelheim Pharma GmbH Co KG
Publication of BR0215560A publication Critical patent/BR0215560A/pt
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44—Nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44—Nitrogen atoms not forming part of a nitro radical
    • C07D233/50—Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

"DERIVADOS DE 2<39>-HALO-3<39>,5<39>-DIALCOXIFEN-1<39>-IL-IMINO-2-IMID AZOLIDINA E O SEU USO PARA O TRATAMENTO DE INCONTINêNCIA URINáRIA". A presente invenção refere-se a 2<39>-halo-3<39>,5<39>-dialcoxifen-1<39>-il-imino-2-imiazolidina, a 2<39>-halo-3<39>,5<39>-dialcoxianilino-2-imiazolidina tautomérica e/ou a seus sais farmacologicamente aceitáveis e a seu uso como composição farmacêutica, no tratamento de incontinência urinária (I).
BR0215560-5A 2002-01-31 2002-12-16 Derivados de 2'-halo-3',5'-dialcoxifen-1'-il-imino-2-imidazolidina e o seu uso para o tratamento de incontinência urinária Pending BR0215560A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02002352A EP1333028A1 (en) 2002-01-31 2002-01-31 2'-Halo-3',5'-dialkoxyphen-1'-yl-imino-2-imidazolidine derivatives and the use thereof for the treatment of urinary incontinence
PCT/EP2002/014299 WO2003064398A1 (en) 2002-01-31 2002-12-16 2'-halo-3',5'-dialkoxyphen-1'-yl-imino-2-imidazolidine derivatives and the use thereof for the treatment of urinary incontinence

Publications (1)

Publication Number Publication Date
BR0215560A true BR0215560A (pt) 2004-12-21

Family

ID=8185397

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0215560-5A Pending BR0215560A (pt) 2002-01-31 2002-12-16 Derivados de 2'-halo-3',5'-dialcoxifen-1'-il-imino-2-imidazolidina e o seu uso para o tratamento de incontinência urinária

Country Status (20)

Country Link
EP (2) EP1333028A1 (pt)
JP (1) JP2005516066A (pt)
KR (1) KR20040074134A (pt)
CN (1) CN1617857A (pt)
AR (1) AR038380A1 (pt)
BR (1) BR0215560A (pt)
CA (1) CA2474588A1 (pt)
EA (1) EA200400877A1 (pt)
EC (1) ECSP045210A (pt)
HR (1) HRP20040691A2 (pt)
HU (1) HUP0402654A2 (pt)
IL (1) IL162776A0 (pt)
MX (1) MXPA04007250A (pt)
NO (1) NO20043614L (pt)
PE (1) PE20030819A1 (pt)
PL (1) PL369826A1 (pt)
TW (1) TW200418462A (pt)
UY (1) UY27628A1 (pt)
WO (1) WO2003064398A1 (pt)
ZA (1) ZA200405173B (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4168086B1 (ja) * 2008-04-16 2008-10-22 国立大学法人福井大学 イミダゾリン誘導体
EP2296648A1 (en) * 2008-05-13 2011-03-23 Allergan, Inc. Naphthylmethylimidizoles for the treatment of stress urinary incontinence
US20090286829A1 (en) * 2008-05-13 2009-11-19 Allergan, Inc. Quinolynylmethylimidizoles as therapeutic agents
WO2009152053A1 (en) * 2008-06-09 2009-12-17 Allergan, Inc. Methods of treating alpha adrenergic mediated conditions using imidazoline derivates
US9034910B2 (en) 2008-06-09 2015-05-19 Allergan, Inc. Methods of treating alpha adrenergic mediated conditions
AU2009257692A1 (en) * 2008-06-09 2009-12-17 Allergan, Inc. Methods of treating alpha adrenergic mediated conditions

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2220906A1 (de) * 1972-04-28 1973-11-15 Boehringer Sohn Ingelheim Neue substituierte 2-phenylaminoimidazoline-(2), deren saeureadditionssalze sowie verfahren zu deren herstellung
DE2259160A1 (de) * 1972-12-02 1974-06-06 Boehringer Sohn Ingelheim Neue substituierte 2-phenylaminoimidazoline, deren saeureadditionssalze und verfahren zur herstellung derselben sowie ihre verwendung als arzneimittel
AT333749B (de) * 1974-07-03 1976-12-10 Chemie Linz Ag Verfahren zur herstellung von neuen 2-arylamino-2-imidazolinderivaten
MTP837B (en) * 1977-11-07 1979-10-22 Hoffman La Roche And Co Aktien Derivatives 2 finino-imidazolidire
DE3514351A1 (de) * 1985-04-20 1986-11-06 Boehringer Ingelheim KG, 6507 Ingelheim Neue substituierte 2-(n-alkinyl-n-phenyl)amino)-imidazolinderivate, deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zu deren herstellung
DE19514579A1 (de) * 1995-04-20 1996-10-24 Boehringer Ingelheim Kg Verwendung von alpha¶1¶¶L¶-Agonisten zur Behandlung der Harninkontinenz
SG72827A1 (en) * 1997-06-23 2000-05-23 Hoffmann La Roche Phenyl-and aminophenyl-alkylsulfonamide and urea derivatives
DE19740176C2 (de) * 1997-09-12 2000-04-06 Lemfoerder Metallwaren Ag Handschaltvorrichtung für ein Kraftfahrzeug

Also Published As

Publication number Publication date
AR038380A1 (es) 2005-01-12
EP1333028A1 (en) 2003-08-06
CA2474588A1 (en) 2003-08-07
HRP20040691A2 (en) 2004-12-31
TW200418462A (en) 2004-10-01
HUP0402654A2 (hu) 2005-03-29
JP2005516066A (ja) 2005-06-02
UY27628A1 (es) 2003-08-29
MXPA04007250A (es) 2004-10-29
KR20040074134A (ko) 2004-08-21
EA200400877A1 (ru) 2005-02-24
PE20030819A1 (es) 2003-10-20
NO20043614L (no) 2004-08-30
CN1617857A (zh) 2005-05-18
PL369826A1 (en) 2005-05-02
EP1472231A1 (en) 2004-11-03
ZA200405173B (en) 2005-06-21
WO2003064398A1 (en) 2003-08-07
ECSP045210A (es) 2004-09-28
IL162776A0 (en) 2005-11-20

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]