HK93590A - Beta-lactam compounds,their preparation and use - Google Patents
Beta-lactam compounds,their preparation and useInfo
- Publication number
- HK93590A HK93590A HK935/90A HK93590A HK93590A HK 93590 A HK93590 A HK 93590A HK 935/90 A HK935/90 A HK 935/90A HK 93590 A HK93590 A HK 93590A HK 93590 A HK93590 A HK 93590A
- Authority
- HK
- Hong Kong
- Prior art keywords
- beta
- preparation
- lactam compounds
- lactam
- compounds
- Prior art date
Links
- -1 Beta-lactam compounds Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C335/30—Isothioureas
- C07C335/32—Isothioureas having sulfur atoms of isothiourea groups bound to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
- C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/568—Four-membered rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB8013563 | 1980-04-24 |
Publications (1)
Publication Number | Publication Date |
---|---|
HK93590A true HK93590A (en) | 1990-11-16 |
Family
ID=10512985
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK935/90A HK93590A (en) | 1980-04-24 | 1990-11-08 | Beta-lactam compounds,their preparation and use |
Country Status (14)
Country | Link |
---|---|
US (2) | US4485110A (xx) |
EP (1) | EP0041768B1 (xx) |
JP (1) | JPH0689004B2 (xx) |
AU (1) | AU547552B2 (xx) |
CA (1) | CA1221356A (xx) |
DE (1) | DE3176517D1 (xx) |
ES (1) | ES8303421A1 (xx) |
GR (1) | GR74493B (xx) |
HK (1) | HK93590A (xx) |
IE (1) | IE53292B1 (xx) |
NZ (1) | NZ196902A (xx) |
PT (1) | PT72914B (xx) |
SG (1) | SG75390G (xx) |
ZA (1) | ZA812708B (xx) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4558042A (en) * | 1981-05-06 | 1985-12-10 | Farmitalia Carlo Erba S.P.A. | β-Lactam-containing antibacterial agents and β-lactamase inhibitors |
JPS58198486A (ja) * | 1982-05-14 | 1983-11-18 | Sankyo Co Ltd | ペネムまたはカルバペネム−3−カルボン酸誘導体およびその製法 |
JPS591464A (ja) * | 1982-06-26 | 1984-01-06 | Sankyo Co Ltd | β−ラクタム化合物及びその製法 |
CA1221358A (en) * | 1982-12-08 | 1987-05-05 | Erba Farmitalia | 2-THIACEPHEM AND (5R)-PENEM DERIVATIVES |
EP0120613A1 (en) * | 1983-03-02 | 1984-10-03 | Beecham Group Plc | Penem derivatives and precursors |
EP0126709B1 (de) * | 1983-03-28 | 1991-04-03 | Ciba-Geigy Ag | Verfahren zur Herstellung von optisch aktiven Azetidinonen |
JPS6028981A (ja) * | 1983-07-27 | 1985-02-14 | Shionogi & Co Ltd | ジオキソラニルペネムカルボン酸誘導体 |
GB8402086D0 (en) * | 1984-01-26 | 1984-02-29 | Beecham Group Plc | Compounds |
FI82471C (fi) * | 1984-01-26 | 1991-03-11 | Beecham Group Plc | Foerfarande foer framstaellning av farmakologiskt aktiva 6-metylenpenemderivater. |
US4826833A (en) * | 1984-01-30 | 1989-05-02 | Pfizer Inc. | 6-(Substituted)methylene-penicillanic and 6-(substituted)hydroxymethylpenicillanic acids and derivatives thereof |
US5015473A (en) * | 1984-01-30 | 1991-05-14 | Pfizer Inc. | 6-(substituted)methylenepenicillanic and 6-(substituted)hydroxymethylpenicillanic acids and derivatives thereof |
US4559333A (en) * | 1984-03-01 | 1985-12-17 | Schering Corporation | Hydrazone substituted penems |
EP0167050A1 (en) * | 1984-06-21 | 1986-01-08 | Beecham Group Plc | Clavulanate compounds, their preparation and use and intermediates thereof |
WO1986000615A1 (en) * | 1984-07-13 | 1986-01-30 | Sanraku Incorporated | New 2-oxoazetidines, process for the preparation and utilization thereof |
GB8518422D0 (en) * | 1985-07-22 | 1985-08-29 | Beecham Group Plc | Compounds |
GB8518421D0 (en) * | 1985-07-22 | 1985-08-29 | Beecham Group Plc | Compounds |
DE3618813A1 (de) * | 1986-06-04 | 1987-12-10 | Hoechst Ag | Pharmazeutische zubereitung zur behandlung bakterieller infektionen |
AT392903B (de) * | 1987-10-08 | 1991-07-10 | Hoechst Ag | Pharmazeutische zubereitung enthaltend ein cephalosporin und ein penemantibiotikum |
EP0416810B1 (en) * | 1989-09-04 | 1995-02-08 | Beecham Group p.l.c. | Cephalosporin compounds, process for their preparation, pharmaceutical compositions and intermediates |
GB9116236D0 (en) * | 1991-07-27 | 1991-09-11 | Smithkline Beecham Plc | Novel compounds |
GB9305837D0 (en) * | 1993-03-20 | 1993-05-05 | Smithkline Beecham Plc | Novel compounds |
US6472383B1 (en) | 1994-04-25 | 2002-10-29 | Smithkline Beecham P.L.C. | Pharmaceutical formulations |
JP3865770B2 (ja) * | 1994-04-25 | 2007-01-10 | スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー | ベータ−ラクタム抗生物質と組み合わせてベータ−ラクタマーゼ阻害性ペネムを含有する医薬製剤および細菌感染の治療におけるそれらの使用 |
US5629306A (en) * | 1994-12-09 | 1997-05-13 | Research Corporation Technologies, Inc. | 7-alkylidene cephalosporanic acid derivatives and methods of using the same |
US6407091B1 (en) | 1999-04-15 | 2002-06-18 | Research Corporation Technologies, Inc. | β-lactamase inhibiting compounds |
US20040132708A1 (en) * | 2002-05-01 | 2004-07-08 | Wyeth | Process for preparing 6-alkylidene penem derivatives |
AR039475A1 (es) | 2002-05-01 | 2005-02-23 | Wyeth Corp | 6-alquiliden-penems triciclicos como inhibidores de beta-lactamasa |
AR039774A1 (es) | 2002-05-01 | 2005-03-02 | Wyeth Corp | 6-alquiliden-penems biciclicos como inhibidores de beta-lactamasas |
TW200621282A (en) * | 2004-08-13 | 2006-07-01 | Wyeth Corp | Stabilizing formulations |
EP1906954A1 (en) * | 2005-07-27 | 2008-04-09 | Wyeth Incoporated | Bicyclic 6-alkylidene-penem b-lactamase inhibitors and -lactam antibiotic combination: a broad spectrum antibiotic |
JP2009502932A (ja) * | 2005-07-27 | 2009-01-29 | ワイス | 三環式6−アルキリデンペネムβ−ラクタマーゼ阻害剤およびβ−ラクタム抗生物質の組み合わせ:広範なスペクトルの抗生物質 |
GT200600380A (es) * | 2005-08-24 | 2007-03-29 | Proceso para la preparacion de inhibidores de beta-lactamasa | |
EP2167081B1 (en) | 2007-05-21 | 2013-06-26 | Hans Rudolf Pfaendler | Bactericidal anti-mrsa active pharmaceutical composition containing carbapenems |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4301074A (en) * | 1977-11-17 | 1981-11-17 | Merck & Co., Inc. | 6-(1'-Hydroxyethyl)-2-substituted-pen-2-em-3-carboxylic acid |
US4123539A (en) * | 1977-12-29 | 1978-10-31 | Merck & Co., Inc. | 6-Ethylpenicillanic acid |
EP0003960B1 (de) * | 1978-02-02 | 1983-06-29 | Ciba-Geigy Ag | 6-Substituierte Thia-Azaverbindungen, ihre Herstellung und diese enthaltende pharmazeutische Präparate |
US4282150A (en) * | 1978-12-18 | 1981-08-04 | Bristol-Myers Company | 2,6-Disubstituted penem compounds |
US4272437A (en) * | 1978-12-18 | 1981-06-09 | Bristol-Myers Company | Antibacterial agents, and 4-thio azetidinone intermediates |
GB2045236A (en) * | 1979-03-26 | 1980-10-29 | Hoechst Uk Ltd | Oxapenem derivatives |
JPS55153789A (en) * | 1979-04-11 | 1980-11-29 | Sankyo Co Ltd | Penem-3-carboxylic acid derivative and its preparation |
US4260598A (en) * | 1979-10-22 | 1981-04-07 | Pfizer Inc. | Method for increasing antibacterial effectiveness of a β-lactam antibiotic |
US4432970A (en) * | 1979-11-23 | 1984-02-21 | Pfizer Inc. | 6-beta-Halopenicillanic acid 1,1-dioxides as beta-lactamase inhibitors |
-
1981
- 1981-04-15 DE DE8181301683T patent/DE3176517D1/de not_active Expired
- 1981-04-15 EP EP81301683A patent/EP0041768B1/en not_active Expired
- 1981-04-21 GR GR64752A patent/GR74493B/el unknown
- 1981-04-22 CA CA000375968A patent/CA1221356A/en not_active Expired
- 1981-04-23 NZ NZ196902A patent/NZ196902A/en unknown
- 1981-04-23 US US06/257,481 patent/US4485110A/en not_active Expired - Lifetime
- 1981-04-23 IE IE906/81A patent/IE53292B1/en unknown
- 1981-04-23 AU AU69762/81A patent/AU547552B2/en not_active Ceased
- 1981-04-24 ZA ZA00812708A patent/ZA812708B/xx unknown
- 1981-04-24 ES ES501645A patent/ES8303421A1/es not_active Expired
- 1981-04-24 PT PT72914A patent/PT72914B/pt unknown
- 1981-04-24 JP JP56062327A patent/JPH0689004B2/ja not_active Expired - Lifetime
-
1984
- 1984-04-23 US US06/602,975 patent/US4560550A/en not_active Expired - Lifetime
-
1990
- 1990-09-12 SG SG753/90A patent/SG75390G/en unknown
- 1990-11-08 HK HK935/90A patent/HK93590A/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
CA1221356A (en) | 1987-05-05 |
IE810906L (en) | 1981-10-24 |
US4560550A (en) | 1985-12-24 |
AU547552B2 (en) | 1985-10-24 |
NZ196902A (en) | 1984-03-30 |
JPS56167689A (en) | 1981-12-23 |
SG75390G (en) | 1990-11-23 |
US4485110A (en) | 1984-11-27 |
IE53292B1 (en) | 1988-10-12 |
EP0041768B1 (en) | 1987-11-11 |
PT72914A (en) | 1981-05-01 |
EP0041768A3 (en) | 1982-01-27 |
ZA812708B (en) | 1982-04-28 |
ES501645A0 (es) | 1983-02-01 |
ES8303421A1 (es) | 1983-02-01 |
DE3176517D1 (en) | 1987-12-17 |
PT72914B (en) | 1982-06-18 |
JPH0689004B2 (ja) | 1994-11-09 |
GR74493B (xx) | 1984-06-28 |
EP0041768A2 (en) | 1981-12-16 |
AU6976281A (en) | 1981-10-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PE | Patent expired |