HK68793A - Biologically active lysine containing octapeptides - Google Patents
Biologically active lysine containing octapeptidesInfo
- Publication number
- HK68793A HK68793A HK687/93A HK68793A HK68793A HK 68793 A HK68793 A HK 68793A HK 687/93 A HK687/93 A HK 687/93A HK 68793 A HK68793 A HK 68793A HK 68793 A HK68793 A HK 68793A
- Authority
- HK
- Hong Kong
- Prior art keywords
- sub
- trp
- cys
- ala
- thr
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/655—Somatostatins
- C07K14/6555—Somatostatins at least 1 amino acid in D-form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/16—Somatostatin; related peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/727,105 US4650787A (en) | 1985-04-25 | 1985-04-25 | Biologically active octapeptides |
US06/843,539 US4725577A (en) | 1985-04-25 | 1986-03-28 | Biologically active lysine containing octapeptides |
Publications (1)
Publication Number | Publication Date |
---|---|
HK68793A true HK68793A (en) | 1993-07-23 |
Family
ID=27111452
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK687/93A HK68793A (en) | 1985-04-25 | 1993-07-15 | Biologically active lysine containing octapeptides |
Country Status (10)
Country | Link |
---|---|
US (1) | US4725577A (xx) |
EP (1) | EP0203031B1 (xx) |
AT (1) | ATE78831T1 (xx) |
AU (1) | AU600895B2 (xx) |
CA (1) | CA1333646C (xx) |
DE (1) | DE3686200T2 (xx) |
DK (1) | DK174920B1 (xx) |
HK (1) | HK68793A (xx) |
IE (1) | IE59621B1 (xx) |
SG (1) | SG57793G (xx) |
Families Citing this family (53)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH085913B2 (ja) * | 1985-09-12 | 1996-01-24 | ザ・アドミニストレ−タ−ズ・オブ・ザ・ツ−レイン・エデユケイシヨナル・フアンド | 治療用ソマトスタチン同族体 |
US4904642A (en) * | 1985-09-12 | 1990-02-27 | The Administrators Of The Tulane Educational Fund | Therapeutic somatostatin analogs |
GR862206B (en) * | 1985-09-12 | 1986-12-31 | Univ Tulane | Therapeutic somatostatin analogs |
US4853371A (en) * | 1986-06-17 | 1989-08-01 | The Administrators Of The Tulane Educational Fund | Therapeutic somatostatin analogs |
DE3726517A1 (de) * | 1986-08-18 | 1988-03-03 | Sandoz Ag | Nasale zusammensetzungen, welche octreotid enthalten |
AU639371B2 (en) * | 1987-07-10 | 1993-07-22 | Novartis Ag | Method of treating breast cancer |
DE3845000C2 (de) * | 1987-07-10 | 1998-11-19 | Novartis Ag | Anwendung von Octreotid zur Behandlung von Brustkrebs |
US5073541A (en) * | 1987-11-18 | 1991-12-17 | Administrators Of The Tulane Educational Fund | Treatment of small cell lung cancer with somatostatin analogs |
US5068221A (en) * | 1989-05-09 | 1991-11-26 | Mathias John R | Treatment of motility disorders with a gnrh analog |
HU221294B1 (en) * | 1989-07-07 | 2002-09-28 | Novartis Ag | Process for producing retarde compositions containing the active ingredient in a polymeric carrier |
PH30995A (en) * | 1989-07-07 | 1997-12-23 | Novartis Inc | Sustained release formulations of water soluble peptides. |
US5538739A (en) * | 1989-07-07 | 1996-07-23 | Sandoz Ltd. | Sustained release formulations of water soluble peptides |
HUT59166A (en) * | 1989-12-08 | 1992-04-28 | Univ Tulane | Process for producing octqpeptide somatostatine analogues with treonine at the 6 position and pharmaceutical compositions containing them |
GB9004017D0 (en) * | 1990-02-22 | 1990-04-18 | Krenning Eric P | Improvements in or relating to organic compounds |
DK0450480T3 (da) * | 1990-04-06 | 1995-08-14 | Univ Tulane | Somatostatinaloger |
US5668254A (en) * | 1990-05-11 | 1997-09-16 | Romano Deghenghi | D-2-alkyl-tryptophan and peptides containing same |
US5872100A (en) * | 1990-05-11 | 1999-02-16 | Deghenghi; Romano | Peptides containing D-2-Alkyl-Tryptophan |
IT1240643B (it) * | 1990-05-11 | 1993-12-17 | Mediolanum Farmaceutici Spa | Peptidi biologicamente attivi contenenti in catena 2-alchiltriptofano |
US5434136A (en) * | 1990-12-14 | 1995-07-18 | Mathias; John R. | Treatment of motility disorders with a GNRH analog |
HU207104B (en) * | 1991-01-25 | 1993-03-01 | Biosignal Kutato Fejlesztoe Kf | Process for producing new somatostatin analogs inhibiting tumour growth and pharmaceutical compositions comprising such compounds |
US5443815A (en) * | 1991-11-27 | 1995-08-22 | Diatech, Inc. | Technetium-99m labeled peptides for imaging |
US5620675A (en) | 1992-06-23 | 1997-04-15 | Diatech, Inc. | Radioactive peptides |
US6017512A (en) * | 1992-06-23 | 2000-01-25 | Diatide, Inc. | Radiolabeled peptides |
US5504069A (en) * | 1993-02-11 | 1996-04-02 | Biomeasure, Inc. | Inhibition of trauma-induced tumor growth |
FR2701952B1 (fr) * | 1993-02-22 | 1995-03-31 | Adir | Nouveaux dérivés cyclopeptidiques de l'angiopeptine, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent. |
DE69434832D1 (de) | 1993-06-23 | 2006-10-05 | Diatide Inc | Radioaktiv-markierte Peptidderivate des Somatostatins zur bildformenden und therapeutischen Verwendung |
US6051206A (en) * | 1994-06-03 | 2000-04-18 | Diatide, Inc | Radiolabeled somatostatin-derived peptides for imaging and therapeutic uses |
US6100377A (en) * | 1994-06-10 | 2000-08-08 | The Trustees Of The University Of Pennsylvania | Constrained peptides |
CZ291798B6 (cs) * | 1994-09-27 | 2003-05-14 | Romano Deghenghi | Peptidy, jejich použití a farmaceutický prostředek s jejich obsahem |
US5597894A (en) * | 1995-06-05 | 1997-01-28 | The Louisiana State University Medical Center Foundation | Multi-tyrosinated somatostatin analogs |
US5830431A (en) * | 1995-06-07 | 1998-11-03 | Mallinckrodt Medical, Inc. | Radiolabeled peptide compositions for site-specific targeting |
US5770687A (en) * | 1995-06-07 | 1998-06-23 | Peptor Limited | Comformationally constrained backbone cyclized somatostatin analogs |
IT1277391B1 (it) * | 1995-07-28 | 1997-11-10 | Romano Deghenghi | Peptidi ciclici analoghi della somatostatina ad attivita' inibitrice dell'ormone della crescita |
JPH09328499A (ja) * | 1996-02-20 | 1997-12-22 | American Cyanamid Co | 純粋なソマトスタチンアンタゴニストおよびその使用方法 |
US6262229B1 (en) | 1996-12-04 | 2001-07-17 | Biomeasure Incorporated | Somatostatin antagonists |
US5972895A (en) * | 1996-12-11 | 1999-10-26 | A. Glenn Braswell | Composition and method for increasing growth hormone levels |
EP1332762A1 (en) * | 1997-05-01 | 2003-08-06 | Cedars-Sinai Medical Center | Method of treating hyperprolactinemia and prolactinomas |
PT979098E (pt) * | 1997-05-01 | 2003-07-31 | Cedars Sinai Medical Center | Metodo para o tratamento da hiperprolactinemia e de prolactinomas |
US5972893A (en) * | 1997-05-06 | 1999-10-26 | Cedars-Sinai Medical Center | Method of treating hyperprolactinemia and prolactinomas |
PT981363E (pt) * | 1997-05-13 | 2003-12-31 | Conseils De Rec Appl Scient S | Somatostatina e agonistas da somatostatina para reduzir o peso corporal |
CA2289499C (en) * | 1997-05-13 | 2010-02-23 | Michael Anthony Cawthorne | Somatostatin and somatostatin agonists for treating insulin insensitivity and syndrome x |
US6004928A (en) * | 1997-05-13 | 1999-12-21 | Biomeasure, Incorporated | Method of treating hyperlipidemia |
WO1998051330A1 (en) * | 1997-05-13 | 1998-11-19 | Societe De Conseils De Recherches Et D'applications Scientifiques S.A. (S.C.R.A.S.) | Method and compositions for treating hyperlipidemia and other conditions |
US5968903A (en) * | 1998-05-07 | 1999-10-19 | Biomeasure, Incorporated | Inhibition of H. pylori proliferation |
NZ530007A (en) | 2001-06-08 | 2006-02-24 | Sod Conseils Rech Applic | Somatostatin-dopamine chimeric analogues that retain both somatostatin and dopamine activity in vivo and display enhanced biological activity |
NZ576739A (en) | 2003-04-22 | 2011-01-28 | Sod Conseils Rech Applic | Peptide vectors for delivering paclitaxel |
US20070111930A1 (en) * | 2005-11-10 | 2007-05-17 | Palle Venkata Raghavendra A | Process for preparing vapreotide |
US8691761B2 (en) | 2006-10-16 | 2014-04-08 | Jean E. F. Rivier | Somatostatin receptor 2 antagonists |
EP2076535B1 (en) * | 2006-10-16 | 2013-03-06 | The Salk Institute For Biological Studies | Receptor(sstr2)-selective somatostatin antagonists |
EP2310028B1 (en) | 2008-06-12 | 2016-11-16 | Ipsen Bioinnovation Limited | Fusion proteins for use in the treatment of acromegaly |
CN107446053A (zh) | 2008-06-12 | 2017-12-08 | 益普生生物创新有限公司 | 癌症的抑制 |
GB0820970D0 (en) | 2008-11-17 | 2008-12-24 | Syntaxin Ltd | Suppression of cancer |
WO2014197938A1 (en) | 2013-06-13 | 2014-12-18 | Antisense Therapeutics Ltd | Combination therapy |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4209426A (en) * | 1979-05-29 | 1980-06-24 | American Home Products Corporation | Polypeptides related to somatostatin |
CY1327A (en) * | 1979-11-27 | 1986-06-27 | Sandoz Ag | Novel polypeptides,processes for their production,pharmaceutical compositions comprising said polypeptides and their use |
US4282143A (en) * | 1980-06-13 | 1981-08-04 | American Home Products Corporation | Octapeptides lowering growth hormone |
DK81082A (da) * | 1981-03-06 | 1982-09-07 | Sandoz Ag | Fremgangsmaade til fremstilling af polypeptider |
US4443434A (en) * | 1982-08-18 | 1984-04-17 | American Home Products Corporation | Antiulcer agent |
CH655505B (xx) * | 1982-08-24 | 1986-04-30 | ||
US4451394A (en) * | 1982-10-25 | 1984-05-29 | American Home Products Corporation | Dodecapeptides preventing glucose and triglyceride assimilation |
US4440904A (en) * | 1983-01-31 | 1984-04-03 | American Home Products Corporation | Nonapeptide anti-secretory agents |
US4684620A (en) * | 1984-09-04 | 1987-08-04 | Gibson-Stephens Neuropharmaceuticals, Inc. | Cyclic polypeptides having mu-receptor specificity |
JPH085913B2 (ja) * | 1985-09-12 | 1996-01-24 | ザ・アドミニストレ−タ−ズ・オブ・ザ・ツ−レイン・エデユケイシヨナル・フアンド | 治療用ソマトスタチン同族体 |
-
1986
- 1986-03-28 US US06/843,539 patent/US4725577A/en not_active Expired - Lifetime
- 1986-04-15 AT AT86810174T patent/ATE78831T1/de not_active IP Right Cessation
- 1986-04-15 EP EP86810174A patent/EP0203031B1/en not_active Expired
- 1986-04-15 DE DE8686810174T patent/DE3686200T2/de not_active Expired - Lifetime
- 1986-04-16 IE IE100486A patent/IE59621B1/en not_active IP Right Cessation
- 1986-04-17 AU AU56338/86A patent/AU600895B2/en not_active Expired
- 1986-04-22 DK DK198601854A patent/DK174920B1/da not_active IP Right Cessation
- 1986-04-24 CA CA000507490A patent/CA1333646C/en not_active Expired - Lifetime
-
1993
- 1993-05-04 SG SG577/93A patent/SG57793G/en unknown
- 1993-07-15 HK HK687/93A patent/HK68793A/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
IE861004L (en) | 1986-10-25 |
US4725577A (en) | 1988-02-16 |
SG57793G (en) | 1993-07-09 |
EP0203031A3 (en) | 1988-09-21 |
DK185486D0 (da) | 1986-04-22 |
DE3686200D1 (de) | 1992-09-03 |
ATE78831T1 (de) | 1992-08-15 |
DK174920B1 (da) | 2004-02-23 |
DE3686200T2 (de) | 1993-03-11 |
AU600895B2 (en) | 1990-08-30 |
CA1333646C (en) | 1994-12-20 |
DK185486A (da) | 1986-10-26 |
IE59621B1 (en) | 1994-03-09 |
AU5633886A (en) | 1986-10-30 |
EP0203031A2 (en) | 1986-11-26 |
EP0203031B1 (en) | 1992-07-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PF | Patent in force | ||
PE | Patent expired |
Effective date: 20060414 |