HK68295A - Process for the preparation of cephalosporin derivatives - Google Patents

Process for the preparation of cephalosporin derivatives Download PDF

Info

Publication number
HK68295A
HK68295A HK68295A HK68295A HK68295A HK 68295 A HK68295 A HK 68295A HK 68295 A HK68295 A HK 68295A HK 68295 A HK68295 A HK 68295A HK 68295 A HK68295 A HK 68295A
Authority
HK
Hong Kong
Prior art keywords
ceftazidime
pentahydrate
dihydrochloride
formula
hydrochloric acid
Prior art date
Application number
HK68295A
Other languages
German (de)
English (en)
French (fr)
Inventor
Christian Prager Bernhard
Original Assignee
Biochemie Gesellschaft M.B.H.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biochemie Gesellschaft M.B.H. filed Critical Biochemie Gesellschaft M.B.H.
Publication of HK68295A publication Critical patent/HK68295A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
HK68295A 1986-10-07 1995-05-04 Process for the preparation of cephalosporin derivatives HK68295A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT0265786A AT387390B (de) 1986-10-07 1986-10-07 Verfahren zur herstellung des antibiotikums (6r,7r)-7-(2-(2-amino-4-thiazolyl)-2-(2-carboxy

Publications (1)

Publication Number Publication Date
HK68295A true HK68295A (en) 1995-05-12

Family

ID=3538212

Family Applications (1)

Application Number Title Priority Date Filing Date
HK68295A HK68295A (en) 1986-10-07 1995-05-04 Process for the preparation of cephalosporin derivatives

Country Status (9)

Country Link
EP (1) EP0267427B1 (enrdf_load_stackoverflow)
JP (2) JP2507505B2 (enrdf_load_stackoverflow)
KR (1) KR950010597B1 (enrdf_load_stackoverflow)
AT (2) AT387390B (enrdf_load_stackoverflow)
DE (1) DE3777537D1 (enrdf_load_stackoverflow)
ES (1) ES2033277T3 (enrdf_load_stackoverflow)
GR (1) GR3004109T3 (enrdf_load_stackoverflow)
HK (1) HK68295A (enrdf_load_stackoverflow)
WO (1) WO1988002752A1 (enrdf_load_stackoverflow)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106317081B (zh) * 2016-08-22 2018-08-31 山东罗欣药业集团恒欣药业有限公司 一种抗感染药物头孢他啶晶体化合物及其药物组合物
CN106432280A (zh) * 2016-09-23 2017-02-22 临沂草之美医药科技有限公司 一种治疗外科手术感染的药物头孢他啶晶体化合物
CN106397458A (zh) * 2016-09-23 2017-02-15 临沂草之美医药科技有限公司 一种治疗外科手术感染的药物头孢他啶晶体化合物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4329453A (en) * 1979-10-02 1982-05-11 Glaxo Group Limited Cephalosporin antibiotic
US4537959A (en) * 1984-03-26 1985-08-27 Eli Lilly And Company Crystalline cephalosporin antibiotic salt
US4616080A (en) * 1984-07-02 1986-10-07 Eli Lilly And Company Simplified process of forming crystalline ceftazidime pentahydrate
EP0187450B1 (en) * 1984-11-08 1991-01-30 Eli Lilly And Company Process for the preparation of crystalline ceftazidime pentahydrate

Also Published As

Publication number Publication date
ATE73809T1 (de) 1992-04-15
KR950010597B1 (ko) 1995-09-20
GR3004109T3 (enrdf_load_stackoverflow) 1993-03-31
EP0267427B1 (de) 1992-03-18
JPH08283272A (ja) 1996-10-29
DE3777537D1 (de) 1992-04-23
JP2594780B2 (ja) 1997-03-26
AT387390B (de) 1989-01-10
KR880701723A (ko) 1988-11-04
ATA265786A (de) 1988-06-15
EP0267427A1 (de) 1988-05-18
WO1988002752A1 (en) 1988-04-21
JPH01500906A (ja) 1989-03-30
ES2033277T3 (es) 1993-03-16
JP2507505B2 (ja) 1996-06-12

Similar Documents

Publication Publication Date Title
EP0127411B1 (en) Method of preparing alpha-l-aspartyl-l-phenylalanine methyl ester and its hydrochloride
CZ54495A3 (en) Process for preparing and/or purification of clavulanic acid
EP0594099B1 (en) Process for the purification of crude clavulanic acid
IE55094B1 (en) Process for preparing l-ascorbic acid
US4294766A (en) Preparation of pure potassium ribonate and ribonolactone
HK68295A (en) Process for the preparation of cephalosporin derivatives
US5166426A (en) Process for producing l-carnitine from d,l-carnitine nitrile salts
CA1155453A (en) Method of producing n-benzyloxycarbonyl-l-aspartic acid
KR100537732B1 (ko) 클라불란산염의제조
US4203903A (en) Process for the recovery of spectinomycin
US4954624A (en) Process for the production of cephalosporin derivatives
US4346045A (en) Process for resolving DL-S-benzoyl-β-mercaptoisobutyric acid, and products obtained
KR950013472B1 (ko) 플루페남산의 2-(2-히드록시에톡시)에탄올아민을 제조하는 방법
JPH02121947A (ja) ２―ケト―ポリヒドロキシ―ｃ↓６―カルボン酸とくに２―ケト―ｌ―グロン酸の水性醗酵排液からの単離法
US3709912A (en) Process for preparing d-ribonolactone
US3983109A (en) Process for recovering cephalosporin C from A fermentation broth as the N-(p-nitrobenzoyl) derivative
JPH0574583B2 (enrdf_load_stackoverflow)
US7476760B2 (en) Purification and production methods of 1-aminocyclopropanecarboxylic acid
US4211883A (en) Process for the production of p-(N-methyl)-aminobenzoyl-L-glutamic acid
US4418016A (en) Method for recovering omega-amino-dodecanoic acid from crystallization mother liquors
EP0357029B1 (en) Method for the production of (-) 2-difluoromethyl-ornithine
EP0819131B1 (en) Purification process
US4484003A (en) Preparation process of β-chloroalanine
KR800001550B1 (ko) 5-(4-히드록시페닐) 히단토인의 제조법
JPS6213936B2 (enrdf_load_stackoverflow)

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)