HK68295A - Process for the preparation of cephalosporin derivatives - Google Patents

Process for the preparation of cephalosporin derivatives

Info

Publication number
HK68295A
HK68295A HK68295A HK68295A HK68295A HK 68295 A HK68295 A HK 68295A HK 68295 A HK68295 A HK 68295A HK 68295 A HK68295 A HK 68295A HK 68295 A HK68295 A HK 68295A
Authority
HK
Hong Kong
Prior art keywords
cephtazidime
pentahydrate
addition
formula
preparation
Prior art date
Application number
HK68295A
Other languages
English (en)
Inventor
Bernhard Christian Prager
Original Assignee
Biochemie Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biochemie Gmbh filed Critical Biochemie Gmbh
Publication of HK68295A publication Critical patent/HK68295A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
HK68295A 1986-10-07 1995-05-04 Process for the preparation of cephalosporin derivatives HK68295A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT0265786A AT387390B (de) 1986-10-07 1986-10-07 Verfahren zur herstellung des antibiotikums (6r,7r)-7-(2-(2-amino-4-thiazolyl)-2-(2-carboxy

Publications (1)

Publication Number Publication Date
HK68295A true HK68295A (en) 1995-05-12

Family

ID=3538212

Family Applications (1)

Application Number Title Priority Date Filing Date
HK68295A HK68295A (en) 1986-10-07 1995-05-04 Process for the preparation of cephalosporin derivatives

Country Status (9)

Country Link
EP (1) EP0267427B1 (xx)
JP (2) JP2507505B2 (xx)
KR (1) KR950010597B1 (xx)
AT (2) AT387390B (xx)
DE (1) DE3777537D1 (xx)
ES (1) ES2033277T3 (xx)
GR (1) GR3004109T3 (xx)
HK (1) HK68295A (xx)
WO (1) WO1988002752A1 (xx)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106317081B (zh) * 2016-08-22 2018-08-31 山东罗欣药业集团恒欣药业有限公司 一种抗感染药物头孢他啶晶体化合物及其药物组合物
CN106397458A (zh) * 2016-09-23 2017-02-15 临沂草之美医药科技有限公司 一种治疗外科手术感染的药物头孢他啶晶体化合物
CN106432280A (zh) * 2016-09-23 2017-02-22 临沂草之美医药科技有限公司 一种治疗外科手术感染的药物头孢他啶晶体化合物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4329453A (en) * 1979-10-02 1982-05-11 Glaxo Group Limited Cephalosporin antibiotic
US4537959A (en) * 1984-03-26 1985-08-27 Eli Lilly And Company Crystalline cephalosporin antibiotic salt
US4616080A (en) * 1984-07-02 1986-10-07 Eli Lilly And Company Simplified process of forming crystalline ceftazidime pentahydrate
CA1239389A (en) * 1984-11-08 1988-07-19 Melvin G. Pleiss, Jr. Crystallization process

Also Published As

Publication number Publication date
ATE73809T1 (de) 1992-04-15
JPH01500906A (ja) 1989-03-30
GR3004109T3 (xx) 1993-03-31
WO1988002752A1 (en) 1988-04-21
ATA265786A (de) 1988-06-15
KR880701723A (ko) 1988-11-04
AT387390B (de) 1989-01-10
ES2033277T3 (es) 1993-03-16
EP0267427A1 (de) 1988-05-18
JP2507505B2 (ja) 1996-06-12
KR950010597B1 (ko) 1995-09-20
DE3777537D1 (de) 1992-04-23
JP2594780B2 (ja) 1997-03-26
EP0267427B1 (de) 1992-03-18
JPH08283272A (ja) 1996-10-29

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)