HK186096A - Fluorination process - Google Patents
Fluorination processInfo
- Publication number
- HK186096A HK186096A HK186096A HK186096A HK186096A HK 186096 A HK186096 A HK 186096A HK 186096 A HK186096 A HK 186096A HK 186096 A HK186096 A HK 186096A HK 186096 A HK186096 A HK 186096A
- Authority
- HK
- Hong Kong
- Prior art keywords
- fluorination process
- alpha
- hydroxy compound
- difluoroalkylamine
- reacting
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/10—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/18—Oxygen atoms
- C07D263/20—Oxygen atoms attached in position 2
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01L—SEMICONDUCTOR DEVICES NOT COVERED BY CLASS H10
- H01L2224/00—Indexing scheme for arrangements for connecting or disconnecting semiconductor or solid-state bodies and methods related thereto as covered by H01L24/00
- H01L2224/01—Means for bonding being attached to, or being formed on, the surface to be connected, e.g. chip-to-package, die-attach, "first-level" interconnects; Manufacturing methods related thereto
- H01L2224/02—Bonding areas; Manufacturing methods related thereto
- H01L2224/04—Structure, shape, material or disposition of the bonding areas prior to the connecting process
- H01L2224/05—Structure, shape, material or disposition of the bonding areas prior to the connecting process of an individual bonding area
- H01L2224/0554—External layer
- H01L2224/0555—Shape
- H01L2224/05552—Shape in top view
- H01L2224/05554—Shape in top view being square
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01L—SEMICONDUCTOR DEVICES NOT COVERED BY CLASS H10
- H01L2224/00—Indexing scheme for arrangements for connecting or disconnecting semiconductor or solid-state bodies and methods related thereto as covered by H01L24/00
- H01L2224/01—Means for bonding being attached to, or being formed on, the surface to be connected, e.g. chip-to-package, die-attach, "first-level" interconnects; Manufacturing methods related thereto
- H01L2224/42—Wire connectors; Manufacturing methods related thereto
- H01L2224/47—Structure, shape, material or disposition of the wire connectors after the connecting process
- H01L2224/48—Structure, shape, material or disposition of the wire connectors after the connecting process of an individual wire connector
- H01L2224/4805—Shape
- H01L2224/4809—Loop shape
- H01L2224/48091—Arched
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01L—SEMICONDUCTOR DEVICES NOT COVERED BY CLASS H10
- H01L2224/00—Indexing scheme for arrangements for connecting or disconnecting semiconductor or solid-state bodies and methods related thereto as covered by H01L24/00
- H01L2224/01—Means for bonding being attached to, or being formed on, the surface to be connected, e.g. chip-to-package, die-attach, "first-level" interconnects; Manufacturing methods related thereto
- H01L2224/42—Wire connectors; Manufacturing methods related thereto
- H01L2224/47—Structure, shape, material or disposition of the wire connectors after the connecting process
- H01L2224/48—Structure, shape, material or disposition of the wire connectors after the connecting process of an individual wire connector
- H01L2224/481—Disposition
- H01L2224/48151—Connecting between a semiconductor or solid-state body and an item not being a semiconductor or solid-state body, e.g. chip-to-substrate, chip-to-passive
- H01L2224/48221—Connecting between a semiconductor or solid-state body and an item not being a semiconductor or solid-state body, e.g. chip-to-substrate, chip-to-passive the body and the item being stacked
- H01L2224/48245—Connecting between a semiconductor or solid-state body and an item not being a semiconductor or solid-state body, e.g. chip-to-substrate, chip-to-passive the body and the item being stacked the item being metallic
- H01L2224/48247—Connecting between a semiconductor or solid-state body and an item not being a semiconductor or solid-state body, e.g. chip-to-substrate, chip-to-passive the body and the item being stacked the item being metallic connecting the wire to a bond pad of the item
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01L—SEMICONDUCTOR DEVICES NOT COVERED BY CLASS H10
- H01L2224/00—Indexing scheme for arrangements for connecting or disconnecting semiconductor or solid-state bodies and methods related thereto as covered by H01L24/00
- H01L2224/01—Means for bonding being attached to, or being formed on, the surface to be connected, e.g. chip-to-package, die-attach, "first-level" interconnects; Manufacturing methods related thereto
- H01L2224/42—Wire connectors; Manufacturing methods related thereto
- H01L2224/47—Structure, shape, material or disposition of the wire connectors after the connecting process
- H01L2224/49—Structure, shape, material or disposition of the wire connectors after the connecting process of a plurality of wire connectors
- H01L2224/491—Disposition
- H01L2224/4912—Layout
- H01L2224/49171—Fan-out arrangements
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Glass Compositions (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Liquid Crystal Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Catalysts (AREA)
- Compounds Of Alkaline-Earth Elements, Aluminum Or Rare-Earth Metals (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/244,210 US4876352A (en) | 1988-09-14 | 1988-09-14 | Pressurized fluorination of hydroxy alkyl groups |
Publications (1)
Publication Number | Publication Date |
---|---|
HK186096A true HK186096A (en) | 1996-10-11 |
Family
ID=22921827
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK186096A HK186096A (en) | 1988-09-14 | 1996-10-03 | Fluorination process |
Country Status (15)
Country | Link |
---|---|
US (1) | US4876352A (ja) |
EP (2) | EP0434732A1 (ja) |
JP (1) | JPH03502695A (ja) |
KR (1) | KR940003288B1 (ja) |
AT (1) | ATE126514T1 (ja) |
AU (1) | AU631141B2 (ja) |
DE (1) | DE68923839T2 (ja) |
ES (1) | ES2075018T3 (ja) |
FI (1) | FI89914C (ja) |
GR (1) | GR3017921T3 (ja) |
HK (1) | HK186096A (ja) |
HU (1) | HU207057B (ja) |
LU (1) | LU88719I2 (ja) |
NO (1) | NO301007B1 (ja) |
WO (1) | WO1990002739A1 (ja) |
Families Citing this family (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5243056A (en) * | 1983-06-02 | 1993-09-07 | Zambon S.P.A. | Intermediates for the preparation of 1-(phenyl)-1-hydroxy-2-amino-3-fluoro propane derivatives |
US5153328A (en) * | 1984-02-03 | 1992-10-06 | Zambon S.P.A. | 2 Hydrocarbyl-4 substituted methyl 5 (4 substituted phenyl)-oxazolines |
US5332835A (en) * | 1984-02-03 | 1994-07-26 | Zambon S.P.A. | Process for fluorinating 1-phenyl-2-amino-1,3-propanediol compounds and new oxazoline compounds useful in this process |
HU9301182D0 (en) * | 1990-10-25 | 1993-08-30 | Schering Corp | Method for producing fluoro-phenicole, its analogues and intermediary compounds |
IT1249048B (it) | 1991-02-21 | 1995-02-11 | Zambon Spa | Processo per la preparazione di trans-(5r)-2-ossazoline -2,4,5, trisostituite |
US5352832A (en) * | 1992-12-18 | 1994-10-04 | Schering Corporation | Asymmetric process for preparing florfenicol, thiamphenicol chloramphenicol and oxazoline intermediates |
DE4437932A1 (de) * | 1994-10-24 | 1996-04-25 | Bayer Ag | Verfahren zur Herstellung von in einer Seitenkette fluorierten Alkyloxazolen und neue, in einer Seitenkette fluorierte Alkyloxazole |
US5663361A (en) * | 1996-08-19 | 1997-09-02 | Schering Corporation | Process for preparing intermediates to florfenicol |
JP2005538937A (ja) * | 2002-03-08 | 2005-12-22 | シェーリング−プラウ, リミテッド | 新規なフロルフェニコール型抗生物質 |
US7439268B2 (en) * | 2003-07-18 | 2008-10-21 | Idexx Laboratories | Compositions containing prodrugs of florfenicol and methods of use |
US20050049210A1 (en) * | 2003-08-27 | 2005-03-03 | Idexx Laboratories, Inc. | Methods for the controlled delivery of pharmacologically active compounds |
US7126005B2 (en) | 2003-10-06 | 2006-10-24 | Aurobindo Pharma Limited | Process for preparing florfenicol |
DE602005012107D1 (de) * | 2004-08-13 | 2009-02-12 | Schering Plough Ltd | Pharmazeutische formulierungen mit einem antibioti |
NZ553777A (en) | 2004-09-23 | 2010-11-26 | Schering Plough Ltd | Control of parasites in animals by the use of novel trifluoromethanesulfonanilide oxime ether derivatives |
WO2006055565A2 (en) * | 2004-11-19 | 2006-05-26 | Schering-Plough Ltd. | Control of parasites in animals by the use of parasiticidal 2-phenyl-3-(1h-pyrrol-2-yl) acrylonitrile derivatives |
AU2005318187B2 (en) * | 2004-12-21 | 2010-12-16 | Intervet International B.V. | Injectable veterinary composition |
PE20070108A1 (es) * | 2005-06-09 | 2007-02-09 | Schering Plough Ltd | Control de parasitos en animales con derivados de n-[(feniloxi)fenil]-1,1,1-trifluorometansulfonamida y de n-[(fenilsulfanil)fenil]-1,1,1-trifluorometansulfonamida |
US8119667B2 (en) * | 2005-12-29 | 2012-02-21 | Schering-Plough Animal Health Corporation | Carbonates of fenicol antibiotics |
US7518017B2 (en) | 2006-02-17 | 2009-04-14 | Idexx Laboratories | Fenicol compounds and methods synthesizing 2-trifluoroacetamido-3-substituted propiophenone compounds |
US20070238700A1 (en) * | 2006-04-10 | 2007-10-11 | Winzenberg Kevin N | N-phenyl-1,1,1-trifluoromethanesulfonamide hydrazone derivative compounds and their usage in controlling parasites |
EP2091909A1 (en) * | 2006-12-13 | 2009-08-26 | Schering-Plough Ltd. | Water-soluble prodrugs of florfenicol and its analogs |
MX2009006467A (es) * | 2006-12-13 | 2009-08-21 | Schering Plough Ltd | Profarmacos solubles en agua de cloranfenicol, tiamfenicol y analogos de los mismos. |
WO2008133901A1 (en) * | 2007-04-27 | 2008-11-06 | Schering-Plough Ltd. | Compounds and methods for enhancing solubility of florfenicol and structurally-related antibiotics using cyclodextrins |
TWI430995B (zh) | 2007-06-26 | 2014-03-21 | Du Pont | 萘異唑啉無脊椎有害動物控制劑 |
MX361762B (es) | 2007-06-27 | 2018-12-17 | Du Pont | Metodo de control de plagas en animales. |
US7550625B2 (en) * | 2007-10-19 | 2009-06-23 | Idexx Laboratories | Esters of florfenicol |
NZ585219A (en) * | 2007-11-09 | 2012-11-30 | Intervet Int Bv | Fast release solid formulation, preparation and use thereof |
TWI401023B (zh) | 2008-02-06 | 2013-07-11 | Du Pont | 中離子農藥 |
WO2010014566A2 (en) * | 2008-07-30 | 2010-02-04 | Intervet International B.V. | Process for preparing oxazoline-protected aminodiol compounds useful as intermediates to florfenicol |
EP2461684A2 (en) | 2009-08-05 | 2012-06-13 | E. I. du Pont de Nemours and Company | Mesoionic pesticides |
UA110924C2 (uk) | 2009-08-05 | 2016-03-10 | Е. І. Дю Пон Де Немур Енд Компані | Мезоіонні пестициди |
UA107804C2 (en) | 2009-08-05 | 2015-02-25 | Du Pont | Mixtures of pesticides mezoionnyh |
CN102574815A (zh) | 2009-08-05 | 2012-07-11 | 杜邦公司 | 介离子杀虫剂 |
BRPI1002023A2 (pt) | 2010-03-01 | 2011-10-25 | Nanocore Biotecnologia S A | forma farmacêutica sólida de dissolução rápida para tratamento de infecções bacterianas |
DK2576523T3 (en) | 2010-05-27 | 2016-04-18 | Du Pont | A crystalline form of 4- [5- [3-chloro-5- (trifluoromethyl) phenyl] -4,5-dihydro-5- (trifluoromethyl) -3-isoxazolyl] -N- [2-oxo-2 - [( 2,2,2-trifluoroethyl) amino] ethyl] - 1-naphthalenecarboxamide |
WO2012087630A1 (en) | 2010-12-20 | 2012-06-28 | E.I. Du Pont De Nemours And Company | Pyridine and pyrimidine compounds for controlling invertebrate |
WO2013158422A1 (en) | 2012-04-17 | 2013-10-24 | E. I. Du Pont De Nemours And Company | Heterocyclic compounds for controlling invertebrate pests |
CN103980168A (zh) * | 2014-05-29 | 2014-08-13 | 京山瑞生制药有限公司 | 一种高纯度氟苯尼考的合成新方法 |
CN106278964B (zh) * | 2016-07-31 | 2018-01-16 | 浙江润康药业有限公司 | 氟苯尼考的制备方法 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3169133A (en) * | 1962-07-02 | 1965-02-09 | Upjohn Co | 3alpha-fluoroandrostanes and 15beta-fluorogesterone |
US3153644A (en) * | 1962-07-31 | 1964-10-20 | Upjohn Co | 16alpha, 17alpha-(2-halo-1-di-lower-alkylamino-2-haloalkylidenedioxy)-steroids and process for the preparation thereof |
US4348393A (en) * | 1978-06-09 | 1982-09-07 | Delalande S.A. | N-Aryl oxazolidinones, oxazolidinethiones, pyrrolidinones, pyrrolidines and thiazolidinones |
US4235892A (en) * | 1979-02-05 | 1980-11-25 | Schering Corporation, Patent Dept. | 1-Aryl-2-acylamido-3-fluoro-1-propanols, methods for their use as antibacterial agents and compositions useful therefor |
ES488154A0 (es) * | 1979-02-05 | 1981-04-16 | Schering Corp | Un procedimiento para la preparacion de un compuesto d-(treo-1-aril-2-acilamido-3-fluor-1-propanol |
EP0677511A3 (en) * | 1983-06-02 | 1996-07-24 | Zambon Spa | Intermediates for the production of 1-phenyl-1-hydroxy-2-amino-3-fluoropropane derivatives. |
US4603422A (en) * | 1984-09-26 | 1986-07-29 | The United States Of America As Represented By The Secretary Of The Navy | Long-lived laser dye |
US4698353A (en) * | 1985-11-13 | 1987-10-06 | Merrell Dow Pharmaceuticals Inc. | Cardiotonic heterocyclic oxazolones |
US4955090A (en) * | 1989-11-13 | 1990-09-11 | Alexander Stefan | Zero gravity toilet |
-
1988
- 1988-09-14 US US07/244,210 patent/US4876352A/en not_active Expired - Lifetime
-
1989
- 1989-09-12 WO PCT/US1989/003826 patent/WO1990002739A1/en active IP Right Grant
- 1989-09-12 JP JP1509847A patent/JPH03502695A/ja active Granted
- 1989-09-12 LU LU88719C patent/LU88719I2/fr unknown
- 1989-09-12 ES ES89116837T patent/ES2075018T3/es not_active Expired - Lifetime
- 1989-09-12 DE DE68923839T patent/DE68923839T2/de not_active Expired - Lifetime
- 1989-09-12 EP EP89910485A patent/EP0434732A1/en active Pending
- 1989-09-12 EP EP89116837A patent/EP0359190B1/en not_active Expired - Lifetime
- 1989-09-12 KR KR1019900700970A patent/KR940003288B1/ko not_active IP Right Cessation
- 1989-09-12 AT AT89116837T patent/ATE126514T1/de not_active IP Right Cessation
- 1989-09-12 AU AU43110/89A patent/AU631141B2/en not_active Expired
- 1989-09-12 HU HU895576A patent/HU207057B/hu unknown
-
1991
- 1991-03-06 NO NO910879A patent/NO301007B1/no not_active IP Right Cessation
- 1991-03-13 FI FI911236A patent/FI89914C/fi active Protection Beyond IP Right Term
-
1995
- 1995-10-31 GR GR950403027T patent/GR3017921T3/el unknown
-
1996
- 1996-10-03 HK HK186096A patent/HK186096A/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
FI911236A0 (fi) | 1991-03-13 |
NO301007B1 (no) | 1997-09-01 |
ATE126514T1 (de) | 1995-09-15 |
AU631141B2 (en) | 1992-11-19 |
AU4311089A (en) | 1990-04-02 |
GR3017921T3 (en) | 1996-01-31 |
EP0359190B1 (en) | 1995-08-16 |
DE68923839T2 (de) | 1995-12-21 |
KR940003288B1 (ko) | 1994-04-20 |
HU895576D0 (en) | 1991-05-28 |
EP0359190A1 (en) | 1990-03-21 |
FI89914C (fi) | 1993-12-10 |
DE68923839D1 (de) | 1995-09-21 |
WO1990002739A1 (en) | 1990-03-22 |
LU88719I2 (fr) | 1996-08-23 |
HUT55766A (en) | 1991-06-28 |
EP0434732A1 (en) | 1991-07-03 |
NO910879L (no) | 1991-03-06 |
NO910879D0 (no) | 1991-03-06 |
HU207057B (en) | 1993-03-01 |
FI89914B (fi) | 1993-08-31 |
JPH0552830B2 (ja) | 1993-08-06 |
KR900701766A (ko) | 1990-12-04 |
JPH03502695A (ja) | 1991-06-20 |
ES2075018T3 (es) | 1995-10-01 |
US4876352A (en) | 1989-10-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PF | Patent in force | ||
PE | Patent expired |
Effective date: 20090911 |