HK1385A - 3-indolyl-tertiary butylaminopropanols - Google Patents

3-indolyl-tertiary butylaminopropanols

Info

Publication number
HK1385A
HK1385A HK13/85A HK1385A HK1385A HK 1385 A HK1385 A HK 1385A HK 13/85 A HK13/85 A HK 13/85A HK 1385 A HK1385 A HK 1385A HK 1385 A HK1385 A HK 1385A
Authority
HK
Hong Kong
Prior art keywords
alkyl
optionally
carboxamido
substituents
phenyl
Prior art date
Application number
HK13/85A
Other languages
English (en)
Inventor
Eugene Kreighbaum William
Timmey Comer William
Original Assignee
Bristol-Myers Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol-Myers Company filed Critical Bristol-Myers Company
Publication of HK1385A publication Critical patent/HK1385A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
HK13/85A 1977-07-13 1985-01-03 3-indolyl-tertiary butylaminopropanols HK1385A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US81513877A 1977-07-13 1977-07-13

Publications (1)

Publication Number Publication Date
HK1385A true HK1385A (en) 1985-01-11

Family

ID=25216976

Family Applications (1)

Application Number Title Priority Date Filing Date
HK13/85A HK1385A (en) 1977-07-13 1985-01-03 3-indolyl-tertiary butylaminopropanols

Country Status (30)

Country Link
JP (1) JPS5419972A (enrdf_load_html_response)
AR (1) AR225274A1 (enrdf_load_html_response)
AT (1) AT364821B (enrdf_load_html_response)
AU (1) AU525064B2 (enrdf_load_html_response)
BE (1) BE868943A (enrdf_load_html_response)
CA (1) CA1116598A (enrdf_load_html_response)
CH (1) CH642066A5 (enrdf_load_html_response)
CY (1) CY1274A (enrdf_load_html_response)
DE (1) DE2830884A1 (enrdf_load_html_response)
DK (1) DK156568C (enrdf_load_html_response)
ES (1) ES471674A1 (enrdf_load_html_response)
FI (1) FI69835C (enrdf_load_html_response)
FR (1) FR2397404A1 (enrdf_load_html_response)
GB (1) GB2001633B (enrdf_load_html_response)
GR (1) GR74488B (enrdf_load_html_response)
HK (1) HK1385A (enrdf_load_html_response)
HU (1) HU178992B (enrdf_load_html_response)
IE (1) IE47122B1 (enrdf_load_html_response)
IL (1) IL55115A (enrdf_load_html_response)
IT (1) IT1105091B (enrdf_load_html_response)
KE (1) KE3485A (enrdf_load_html_response)
LU (1) LU79966A1 (enrdf_load_html_response)
MY (1) MY8500946A (enrdf_load_html_response)
NL (1) NL189946C (enrdf_load_html_response)
NO (1) NO149311C (enrdf_load_html_response)
NZ (1) NZ187763A (enrdf_load_html_response)
SE (1) SE429339B (enrdf_load_html_response)
SG (1) SG82584G (enrdf_load_html_response)
YU (1) YU40528B (enrdf_load_html_response)
ZA (1) ZA783744B (enrdf_load_html_response)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2463765A1 (fr) * 1979-08-17 1981-02-27 Clin Midy Nouveaux derives de l'indole actifs sur le systeme cardiovasculaire
US4321398A (en) * 1981-05-07 1982-03-23 Mead Johnson & Company Thienyl and benzothienyl-tertiary butylaminophenoxypropanols
DE3119796A1 (de) * 1981-05-19 1982-12-23 Hoechst Ag, 6000 Frankfurt Substituierte tryptaminderivate von thienyloxpropanolaminen, verfahren zu ihrer herstellung, pharmazeutische praeparate auf basis dieser verbindungen sowie ihre verwendung
FR2523964B1 (fr) * 1982-03-23 1985-09-27 Sanofi Sa Nouveaux derives de la tryptamine actifs notamment sur le systeme cardiovasculaire et procede pour leur preparation
NZ208337A (en) * 1983-06-10 1988-10-28 Bristol Myers Co 2-(2-hydroxy-3-((2-(ar-hydroxy-1h-aminopropoxy-yl)ethyl benzonitriles and pharmaceutical compositions
FR2601008B1 (fr) * 1986-07-03 1990-03-30 Sanofi Sa Procede de synthese stereospecifique de derives de l'indole
ATE329901T1 (de) 2000-11-10 2006-07-15 Lilly Co Eli 3-substituierte oxindolderivate als beta-3- agonisten
DE60215028T2 (de) * 2001-08-14 2007-03-15 Eli Lilly And Co., Indianapolis Indol derivate als beta-3-adrenerge agonisten zur behandlung von typ 2 diabetes
EP1444224B1 (en) 2001-08-14 2006-05-03 Eli Lilly And Company 3-substituted oxindole beta-3 agonists
EP1448561B1 (en) 2001-11-20 2008-02-20 Eli Lilly And Company Beta 3 adrenergic agonists
EP1448560B1 (en) 2001-11-20 2005-06-15 Eli Lilly And Company 3-SUBSTITUTED OXINDOLE beta 3 AGONISTS
JP2005520805A (ja) 2002-01-11 2005-07-14 イーライ・リリー・アンド・カンパニー ２−オキソ−ベンズイミダゾリル置換型エタノールアミン誘導体およびβ３アゴニストとしてのその使用
CA2732513C (en) 2008-08-01 2017-04-25 Arca Biopharma, Inc. Methods and compositions involving (s)-bucindolol

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1532210A (fr) * 1963-06-21 1968-07-12 Ici Ltd Composés hétérocycliques et leur procédé de préparation
CH495983A (de) * 1968-02-09 1970-09-15 Sandoz Ag Verfahren zur Herstellung von linksdrehendem 4-(2-Hydroxy-3-isopropylaminopropoxy)indol
US3371098A (en) * 1966-11-29 1968-02-27 Philips Corp 5- and 6-methoxy-3-(phenoxyethyl-aminoethyl)-indoles
US3946009A (en) * 1972-05-05 1976-03-23 Merck Sharp & Dohme (I.A.) Corporation 2-(3-Substituted amino-2-hydroxypropoxy)-3-substituted pyrazines

Also Published As

Publication number Publication date
NZ187763A (en) 1984-07-31
NO149311B (no) 1983-12-19
DE2830884C2 (enrdf_load_html_response) 1990-01-11
NO149311C (no) 1984-03-28
JPS5419972A (en) 1979-02-15
IE47122B1 (en) 1983-12-28
CA1116598A (en) 1982-01-19
CH642066A5 (de) 1984-03-30
GB2001633B (en) 1982-03-24
FI69835B (fi) 1985-12-31
ATA508978A (de) 1981-04-15
FI782205A7 (fi) 1979-01-14
DK156568B (da) 1989-09-11
DK156568C (da) 1990-02-05
MY8500946A (en) 1985-12-31
IT7850228A0 (it) 1978-07-10
AU3770478A (en) 1980-01-10
HU178992B (en) 1982-07-28
BE868943A (fr) 1979-01-12
DE2830884A1 (de) 1979-02-01
SE429339B (sv) 1983-08-29
IT1105091B (it) 1985-10-28
IL55115A (en) 1981-09-13
IE781400L (en) 1979-01-13
LU79966A1 (fr) 1979-04-09
NL189946B (nl) 1993-04-16
SG82584G (en) 1985-09-13
JPS6340784B2 (enrdf_load_html_response) 1988-08-12
CY1274A (en) 1985-03-08
ES471674A1 (es) 1979-10-01
AT364821B (de) 1981-11-25
IL55115A0 (en) 1978-09-29
FI69835C (fi) 1986-05-26
FR2397404B1 (enrdf_load_html_response) 1982-06-11
FR2397404A1 (fr) 1979-02-09
GB2001633A (en) 1979-02-07
SE7807700L (sv) 1979-01-14
KE3485A (en) 1985-01-25
NL7807564A (nl) 1979-01-16
NO782407L (no) 1979-01-16
GR74488B (enrdf_load_html_response) 1984-06-28
AR225274A1 (es) 1982-03-15
AU525064B2 (en) 1982-10-21
YU40528B (en) 1986-02-28
DK313878A (da) 1979-01-14
NL189946C (nl) 1993-09-16
ZA783744B (en) 1979-07-25
YU161178A (en) 1983-02-28

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Legal Events

Date Code Title Description
PE Patent expired