HK1259279A1 - 用於細胞封裝和細胞治療的改性藻朊酸鹽 - Google Patents

用於細胞封裝和細胞治療的改性藻朊酸鹽

Info

Publication number
HK1259279A1
HK1259279A1 HK19101640.1A HK19101640A HK1259279A1 HK 1259279 A1 HK1259279 A1 HK 1259279A1 HK 19101640 A HK19101640 A HK 19101640A HK 1259279 A1 HK1259279 A1 HK 1259279A1
Authority
HK
Hong Kong
Prior art keywords
cell
modified alginates
encapsulation
therapy
cell therapy
Prior art date
Application number
HK19101640.1A
Other languages
English (en)
Inventor
Arturo J Vegas
Minglin Ma
Kaitlin M Bratlie
Daniel G Anderson
Robert S Langer
Original Assignee
Massachusetts Inst Technology
Childrens Medical Ct Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Massachusetts Inst Technology, Childrens Medical Ct Corp filed Critical Massachusetts Inst Technology
Publication of HK1259279A1 publication Critical patent/HK1259279A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0084—Guluromannuronans, e.g. alginic acid, i.e. D-mannuronic acid and D-guluronic acid units linked with alternating alpha- and beta-1,4-glycosidic bonds; Derivatives thereof, e.g. alginates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/37—Digestive system
    • A61K35/39—Pancreas; Islets of Langerhans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5161—Polysaccharides, e.g. alginate, chitosan, cellulose derivatives; Cyclodextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Zoology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Biotechnology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK19101640.1A 2011-06-02 2019-01-30 用於細胞封裝和細胞治療的改性藻朊酸鹽 HK1259279A1 (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161492705P 2011-06-02 2011-06-02

Publications (1)

Publication Number Publication Date
HK1259279A1 true HK1259279A1 (zh) 2019-11-29

Family

ID=46321466

Family Applications (1)

Application Number Title Priority Date Filing Date
HK19101640.1A HK1259279A1 (zh) 2011-06-02 2019-01-30 用於細胞封裝和細胞治療的改性藻朊酸鹽

Country Status (7)

Country Link
US (6) US9422373B2 (zh)
EP (3) EP2714747B1 (zh)
CA (1) CA2837558C (zh)
DK (1) DK3354665T5 (zh)
ES (1) ES2912545T3 (zh)
HK (1) HK1259279A1 (zh)
WO (1) WO2012167223A1 (zh)

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US20210353781A1 (en) * 2018-09-21 2021-11-18 Massachusetts Institute Of Technology Surface-modified cells, methods of making and using
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US20220089537A1 (en) 2020-09-18 2022-03-24 Massachusetts Institute Of Technology High-throughput method to rapidly add chemical moieties to a small molecule library
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Also Published As

Publication number Publication date
US20120308650A1 (en) 2012-12-06
US20160324793A1 (en) 2016-11-10
US10292936B2 (en) 2019-05-21
ES2912545T3 (es) 2022-05-26
EP2714747B1 (en) 2020-08-05
US20210186886A1 (en) 2021-06-24
DK3354665T5 (da) 2022-09-19
US20230130084A1 (en) 2023-04-27
US10285949B2 (en) 2019-05-14
CA2837558C (en) 2018-11-20
EP4083074A1 (en) 2022-11-02
US10842753B2 (en) 2020-11-24
EP3354665B1 (en) 2022-03-30
US9422373B2 (en) 2016-08-23
EP2714747A1 (en) 2014-04-09
WO2012167223A1 (en) 2012-12-06
EP3354665A1 (en) 2018-08-01
US11337930B2 (en) 2022-05-24
CA2837558A1 (en) 2012-12-06
US20170239190A1 (en) 2017-08-24
US20190262272A1 (en) 2019-08-29
EP3354665B9 (en) 2022-08-03
DK3354665T3 (da) 2022-04-25

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