HK1257122A1 - Lrp5作为用於鉴定免疫细胞特别是b细胞的表观遗传标志物 - Google Patents
Lrp5作为用於鉴定免疫细胞特别是b细胞的表观遗传标志物 Download PDFInfo
- Publication number
- HK1257122A1 HK1257122A1 HK18116376.0A HK18116376A HK1257122A1 HK 1257122 A1 HK1257122 A1 HK 1257122A1 HK 18116376 A HK18116376 A HK 18116376A HK 1257122 A1 HK1257122 A1 HK 1257122A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- cells
- lrp5
- methylation
- identification
- cell
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/154—Methylation markers
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- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Analytical Chemistry (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1516972.5 | 2015-09-25 | ||
| GBGB1516972.5A GB201516972D0 (en) | 2015-09-25 | 2015-09-25 | LRP5 as epigenetic marker for the identification of immune cells, in particular B-cells |
| PCT/EP2016/072579 WO2017050916A1 (en) | 2015-09-25 | 2016-09-22 | Lrp5 as epigenetic marker for the identification of immune cells, in particular b-cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1257122A1 true HK1257122A1 (zh) | 2019-10-11 |
Family
ID=54544102
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK18116376.0A HK1257122A1 (zh) | 2015-09-25 | 2016-09-22 | Lrp5作为用於鉴定免疫细胞特别是b细胞的表观遗传标志物 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US11643687B2 (https=) |
| EP (1) | EP3353318B1 (https=) |
| JP (1) | JP2018529345A (https=) |
| CN (1) | CN108026578A (https=) |
| GB (1) | GB201516972D0 (https=) |
| HK (1) | HK1257122A1 (https=) |
| WO (1) | WO2017050916A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3652344A1 (en) * | 2017-07-13 | 2020-05-20 | Yissum Research and Development Company of the Hebrew University of Jerusalem Ltd. | Dna targets as tissue-specific methylation markers |
| WO2019184886A1 (zh) * | 2018-03-26 | 2019-10-03 | 上海原能细胞医学技术有限公司 | 促进免疫细胞增殖的方法 |
| DE102018112644B4 (de) * | 2018-05-25 | 2020-06-10 | Epiontis Gmbh | CXCR3 als epigenetischer Marker zur Identifizierung von inflammatorischen Immunzellen, insbesondere CD8+ Gedächnis-T-Zellen |
| DE102018116353B4 (de) * | 2018-07-05 | 2020-06-10 | Epiontis Gmbh | Verfahren zum Nachweis und zur Zählung epigenetischer Immunzellen in humanen Blutproben für Immundiagnostik und Neugeborenen-Screening |
| DE102020108560B4 (de) | 2020-03-27 | 2022-03-03 | Precision For Medicine Gmbh | CBX6 als epigenetischer Marker für die Identifizierung von Immunzellen, insbesondere Gedächtnis-B-Zellen |
| CN119372296B (zh) * | 2024-12-24 | 2025-06-13 | 北京致谱医学检验实验室有限公司 | 基于基因甲基化检测实现人b淋巴细胞计数的试剂盒 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE60129433T2 (de) * | 2000-05-26 | 2008-04-17 | Oscient Pharmaceuticals Corp., Waltham | Regulation des lipidniveaus über die gene zmax1 oder hbm |
| DK1826279T3 (da) * | 2006-02-28 | 2011-09-05 | Charite Universitaetsmedizin | Detektering og kvalitetskontrol af regulatoriske t-celler vha. DNA-metyleringsanalyse af FoxP3--genet |
| CN101909630A (zh) * | 2007-11-02 | 2010-12-08 | 新加坡科技研究局 | 预防和治疗肿瘤的方法和化合物 |
| US20110104695A1 (en) * | 2009-11-05 | 2011-05-05 | Epigenomics Ag | Methods of predicting therapeutic efficacy of cancer therapy |
| WO2012045888A1 (en) * | 2010-10-08 | 2012-04-12 | Epiontis Gmbh | Method for determining cancer patient survival based on analyzing tumor-infiltrating overall t-lymphocytes |
| WO2013033627A2 (en) | 2011-09-01 | 2013-03-07 | The Regents Of The University Of California | Diagnosis and treatment of arthritis using epigenetics |
| US10208346B2 (en) * | 2013-04-19 | 2019-02-19 | Epiontis Gmbh | Method for identifying the quantitative cellular composition in a biological sample |
| ES2827241T3 (es) * | 2014-05-30 | 2021-05-20 | Robert Philibert | Estado de metilación del ADN como un biomarcador del consumo y la abstinencia del alcohol |
-
2015
- 2015-09-25 GB GBGB1516972.5A patent/GB201516972D0/en not_active Ceased
-
2016
- 2016-09-22 WO PCT/EP2016/072579 patent/WO2017050916A1/en not_active Ceased
- 2016-09-22 HK HK18116376.0A patent/HK1257122A1/zh unknown
- 2016-09-22 EP EP16770025.1A patent/EP3353318B1/en active Active
- 2016-09-22 US US15/752,072 patent/US11643687B2/en active Active
- 2016-09-22 CN CN201680052685.1A patent/CN108026578A/zh active Pending
- 2016-09-22 JP JP2018515528A patent/JP2018529345A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2018529345A (ja) | 2018-10-11 |
| EP3353318A1 (en) | 2018-08-01 |
| WO2017050916A1 (en) | 2017-03-30 |
| US20180216185A1 (en) | 2018-08-02 |
| US11643687B2 (en) | 2023-05-09 |
| CA2999611A1 (en) | 2017-03-30 |
| CN108026578A (zh) | 2018-05-11 |
| GB201516972D0 (en) | 2015-11-11 |
| EP3353318B1 (en) | 2021-03-10 |
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