GB201516972D0 - LRP5 as epigenetic marker for the identification of immune cells, in particular B-cells - Google Patents

LRP5 as epigenetic marker for the identification of immune cells, in particular B-cells

Info

Publication number
GB201516972D0
GB201516972D0 GBGB1516972.5A GB201516972A GB201516972D0 GB 201516972 D0 GB201516972 D0 GB 201516972D0 GB 201516972 A GB201516972 A GB 201516972A GB 201516972 D0 GB201516972 D0 GB 201516972D0
Authority
GB
United Kingdom
Prior art keywords
cells
lrp5
identification
epigenetic marker
immune cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB1516972.5A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Precision for Medicine GmbH
Original Assignee
Epiontis GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Epiontis GmbH filed Critical Epiontis GmbH
Priority to GBGB1516972.5A priority Critical patent/GB201516972D0/en
Publication of GB201516972D0 publication Critical patent/GB201516972D0/en
Priority to CA2999611A priority patent/CA2999611C/en
Priority to PCT/EP2016/072579 priority patent/WO2017050916A1/en
Priority to US15/752,072 priority patent/US11643687B2/en
Priority to HK18116376.0A priority patent/HK1257122A1/zh
Priority to CN201680052685.1A priority patent/CN108026578A/zh
Priority to JP2018515528A priority patent/JP2018529345A/ja
Priority to EP16770025.1A priority patent/EP3353318B1/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/154—Methylation markers

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
GBGB1516972.5A 2015-09-25 2015-09-25 LRP5 as epigenetic marker for the identification of immune cells, in particular B-cells Ceased GB201516972D0 (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
GBGB1516972.5A GB201516972D0 (en) 2015-09-25 2015-09-25 LRP5 as epigenetic marker for the identification of immune cells, in particular B-cells
CA2999611A CA2999611C (en) 2015-09-25 2016-09-22 Lrp5 as epigenetic marker for the identification of immune cells, in particular b-cells
PCT/EP2016/072579 WO2017050916A1 (en) 2015-09-25 2016-09-22 Lrp5 as epigenetic marker for the identification of immune cells, in particular b-cells
US15/752,072 US11643687B2 (en) 2015-09-25 2016-09-22 LRP5 as epigenetic marker for the identification of immune cells, in particular B-cells
HK18116376.0A HK1257122A1 (zh) 2015-09-25 2016-09-22 Lrp5作为用於鉴定免疫细胞特别是b细胞的表观遗传标志物
CN201680052685.1A CN108026578A (zh) 2015-09-25 2016-09-22 Lrp5作为用于鉴定免疫细胞特别是b细胞的表观遗传标志物
JP2018515528A JP2018529345A (ja) 2015-09-25 2016-09-22 免疫細胞、特にｂ細胞の同定のためのエピジェネティックマーカーとしてのｌｒｐ５
EP16770025.1A EP3353318B1 (en) 2015-09-25 2016-09-22 Lrp5 as epigenetic marker for the identification of immune cells, in particular b-cells

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1516972.5A GB201516972D0 (en) 2015-09-25 2015-09-25 LRP5 as epigenetic marker for the identification of immune cells, in particular B-cells

Publications (1)

Publication Number Publication Date
GB201516972D0 true GB201516972D0 (en) 2015-11-11

Family

ID=54544102

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB1516972.5A Ceased GB201516972D0 (en) 2015-09-25 2015-09-25 LRP5 as epigenetic marker for the identification of immune cells, in particular B-cells

Country Status (7)

Country Link
US (1) US11643687B2 (https=)
EP (1) EP3353318B1 (https=)
JP (1) JP2018529345A (https=)
CN (1) CN108026578A (https=)
GB (1) GB201516972D0 (https=)
HK (1) HK1257122A1 (https=)
WO (1) WO2017050916A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3652344A1 (en) * 2017-07-13 2020-05-20 Yissum Research and Development Company of the Hebrew University of Jerusalem Ltd. Dna targets as tissue-specific methylation markers
US12005080B2 (en) 2018-03-26 2024-06-11 Oricell Therapeutics Co., Ltd. Method for promoting proliferation of immune cells
DE102018112644B4 (de) 2018-05-25 2020-06-10 Epiontis Gmbh CXCR3 als epigenetischer Marker zur Identifizierung von inflammatorischen Immunzellen, insbesondere CD8+ Gedächnis-T-Zellen
DE102018116353B4 (de) * 2018-07-05 2020-06-10 Epiontis Gmbh Verfahren zum Nachweis und zur Zählung epigenetischer Immunzellen in humanen Blutproben für Immundiagnostik und Neugeborenen-Screening
DE102020108560B4 (de) 2020-03-27 2022-03-03 Precision For Medicine Gmbh CBX6 als epigenetischer Marker für die Identifizierung von Immunzellen, insbesondere Gedächtnis-B-Zellen
CN119372296B (zh) * 2024-12-24 2025-06-13 北京致谱医学检验实验室有限公司 基于基因甲基化检测实现人b淋巴细胞计数的试剂盒

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2410253C (en) * 2000-05-26 2010-06-15 Genome Therapeutics Corporation Regulating lipid levels via the zmax1 or hbm gene
ES2367012T3 (es) * 2006-02-28 2011-10-27 Charite-Universitätsmedizin Berlin Detección y control de calidad de linfocitos t reguladores a través del análisis de metilación del adn del gen foxp3.
CN101909630A (zh) * 2007-11-02 2010-12-08 新加坡科技研究局 预防和治疗肿瘤的方法和化合物
US20110104695A1 (en) * 2009-11-05 2011-05-05 Epigenomics Ag Methods of predicting therapeutic efficacy of cancer therapy
WO2012045888A1 (en) * 2010-10-08 2012-04-12 Epiontis Gmbh Method for determining cancer patient survival based on analyzing tumor-infiltrating overall t-lymphocytes
WO2013033627A2 (en) 2011-09-01 2013-03-07 The Regents Of The University Of California Diagnosis and treatment of arthritis using epigenetics
JP6590790B2 (ja) * 2013-04-19 2019-10-16 エピオンティス ゲーエムベーハー 生体サンプルにおける定量的細胞組成を特定する方法
EP3149206B1 (en) * 2014-05-30 2020-09-02 Robert Philibert Dna methylation status as a biomarker of alcohol use and abstinence

Also Published As

Publication number Publication date
HK1257122A1 (zh) 2019-10-11
CA2999611A1 (en) 2017-03-30
US20180216185A1 (en) 2018-08-02
WO2017050916A1 (en) 2017-03-30
EP3353318B1 (en) 2021-03-10
JP2018529345A (ja) 2018-10-11
EP3353318A1 (en) 2018-08-01
CN108026578A (zh) 2018-05-11
US11643687B2 (en) 2023-05-09

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)