HK1256823A1 - 用α-2B腎上腺素能受體激動劑活化調節T細胞的方法 - Google Patents

用α-2B腎上腺素能受體激動劑活化調節T細胞的方法

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Publication number
HK1256823A1
HK1256823A1 HK18115908.9A HK18115908A HK1256823A1 HK 1256823 A1 HK1256823 A1 HK 1256823A1 HK 18115908 A HK18115908 A HK 18115908A HK 1256823 A1 HK1256823 A1 HK 1256823A1
Authority
HK
Hong Kong
Prior art keywords
alpha
cells
receptor agonists
adrenergic receptor
activating regulatory
Prior art date
Application number
HK18115908.9A
Other languages
English (en)
Inventor
Daniel W Gil
John E Donello
Lauren M B Luhrs
Veena Viswanath
Original Assignee
Allergan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allergan Inc filed Critical Allergan Inc
Publication of HK1256823A1 publication Critical patent/HK1256823A1/zh

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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/17Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41681,3-Diazoles having a nitrogen attached in position 2, e.g. clonidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41781,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • A61K31/4211,3-Oxazoles, e.g. pemoline, trimethadione
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HK18115908.9A 2010-08-16 2018-12-12 用α-2B腎上腺素能受體激動劑活化調節T細胞的方法 HK1256823A1 (zh)

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HK19100420.9A HK1258043A1 (zh) 2010-08-16 2019-01-11 用α-2B腎上腺素能受體激動劑活化調節T細胞的方法

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US (5) US8575207B2 (zh)
EP (2) EP3332782A1 (zh)
JP (3) JP5938407B2 (zh)
KR (3) KR102013086B1 (zh)
CN (3) CN108272797B (zh)
AU (1) AU2011292296B2 (zh)
BR (1) BR112013003590A2 (zh)
CA (1) CA2808307C (zh)
DK (1) DK2605771T3 (zh)
ES (1) ES2676194T3 (zh)
HK (2) HK1256823A1 (zh)
HU (1) HUE038366T2 (zh)
PL (1) PL2605771T3 (zh)
PT (1) PT2605771T (zh)
RU (2) RU2016134989A (zh)
SI (1) SI2605771T1 (zh)
TR (1) TR201809456T4 (zh)
WO (1) WO2012024161A1 (zh)

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US20180071259A1 (en) 2018-03-15
JP6250728B2 (ja) 2017-12-20
RU2016134989A (ru) 2018-12-11
US20120041031A1 (en) 2012-02-16
WO2012024161A1 (en) 2012-02-23
CA2808307C (en) 2022-06-21
KR20130108301A (ko) 2013-10-02
PL2605771T3 (pl) 2018-10-31
ES2676194T3 (es) 2018-07-17
US20160158199A1 (en) 2016-06-09
EP2605771B1 (en) 2018-04-04
EP3332782A1 (en) 2018-06-13
JP5938407B2 (ja) 2016-06-22
EP2605771A1 (en) 2013-06-26
BR112013003590A2 (pt) 2016-05-31
JP2013534246A (ja) 2013-09-02
CN114073696A (zh) 2022-02-22
CA2808307A1 (en) 2012-02-23
JP2016117781A (ja) 2016-06-30
DK2605771T3 (en) 2018-07-16
US10251865B2 (en) 2019-04-09
TR201809456T4 (tr) 2018-07-23
CN108272797A (zh) 2018-07-13
KR20190097323A (ko) 2019-08-20
PT2605771T (pt) 2018-07-09
US9545394B2 (en) 2017-01-17
CN103153296B (zh) 2018-02-13
AU2011292296A1 (en) 2013-03-14
US8575207B2 (en) 2013-11-05
CN108272797B (zh) 2021-04-27
AU2011292296B2 (en) 2015-09-03
US9289420B2 (en) 2016-03-22
SI2605771T1 (sl) 2018-09-28
JP2018027984A (ja) 2018-02-22
RU2016134989A3 (zh) 2020-02-17
CN103153296A (zh) 2013-06-12
KR102013086B1 (ko) 2019-08-21
US20170079956A1 (en) 2017-03-23
KR20180040710A (ko) 2018-04-20
HUE038366T2 (hu) 2018-10-29
RU2013110877A (ru) 2014-09-27
US20140066483A1 (en) 2014-03-06
RU2599495C2 (ru) 2016-10-10
HK1258043A1 (zh) 2019-11-01
KR101847669B1 (ko) 2018-05-24
JP6509307B2 (ja) 2019-05-08

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