HK1258043A1 - 用α-2B腎上腺素能受體激動劑活化調節T細胞的方法 - Google Patents

用α-2B腎上腺素能受體激動劑活化調節T細胞的方法

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Publication number
HK1258043A1
HK1258043A1 HK19100420.9A HK19100420A HK1258043A1 HK 1258043 A1 HK1258043 A1 HK 1258043A1 HK 19100420 A HK19100420 A HK 19100420A HK 1258043 A1 HK1258043 A1 HK 1258043A1
Authority
HK
Hong Kong
Prior art keywords
alpha
cells
receptor agonists
adrenergic receptor
activating regulatory
Prior art date
Application number
HK19100420.9A
Other languages
English (en)
Inventor
Daniel W Gil
John E Donello
Lauren M B Luhrs
Veena Viswanath
Original Assignee
Allergan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allergan Inc filed Critical Allergan Inc
Publication of HK1258043A1 publication Critical patent/HK1258043A1/zh

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    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4168—1,3-Diazoles having a nitrogen attached in position 2, e.g. clonidine
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/421—1,3-Oxazoles, e.g. pemoline, trimethadione
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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  • Psychiatry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hospice & Palliative Care (AREA)
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  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HK19100420.9A 2010-08-16 2019-01-11 用α-2B腎上腺素能受體激動劑活化調節T細胞的方法 HK1258043A1 (zh)

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US37412410P 2010-08-16 2010-08-16

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HK18115908.9A HK1256823A1 (zh) 2010-08-16 2018-12-12 用α-2B腎上腺素能受體激動劑活化調節T細胞的方法
HK19100420.9A HK1258043A1 (zh) 2010-08-16 2019-01-11 用α-2B腎上腺素能受體激動劑活化調節T細胞的方法

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Country Status (18)

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US (5) US8575207B2 (zh)
EP (2) EP3332782A1 (zh)
JP (3) JP5938407B2 (zh)
KR (3) KR102013086B1 (zh)
CN (3) CN114073696A (zh)
AU (1) AU2011292296B2 (zh)
BR (1) BR112013003590A2 (zh)
CA (1) CA2808307C (zh)
DK (1) DK2605771T3 (zh)
ES (1) ES2676194T3 (zh)
HK (2) HK1256823A1 (zh)
HU (1) HUE038366T2 (zh)
PL (1) PL2605771T3 (zh)
PT (1) PT2605771T (zh)
RU (2) RU2016134989A (zh)
SI (1) SI2605771T1 (zh)
TR (1) TR201809456T4 (zh)
WO (1) WO2012024161A1 (zh)

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EP3332782A1 (en) 2018-06-13
KR20180040710A (ko) 2018-04-20
CA2808307A1 (en) 2012-02-23
US8575207B2 (en) 2013-11-05
SI2605771T1 (sl) 2018-09-28
AU2011292296A1 (en) 2013-03-14
US20160158199A1 (en) 2016-06-09
HUE038366T2 (hu) 2018-10-29
HK1256823A1 (zh) 2019-10-04
RU2013110877A (ru) 2014-09-27
PL2605771T3 (pl) 2018-10-31
TR201809456T4 (tr) 2018-07-23
US20180071259A1 (en) 2018-03-15
US9289420B2 (en) 2016-03-22
RU2016134989A3 (zh) 2020-02-17
CA2808307C (en) 2022-06-21
AU2011292296B2 (en) 2015-09-03
CN108272797A (zh) 2018-07-13
CN108272797B (zh) 2021-04-27
US20170079956A1 (en) 2017-03-23
KR102013086B1 (ko) 2019-08-21
JP6509307B2 (ja) 2019-05-08
US20120041031A1 (en) 2012-02-16
RU2599495C2 (ru) 2016-10-10
US10251865B2 (en) 2019-04-09
US9545394B2 (en) 2017-01-17
CN114073696A (zh) 2022-02-22
BR112013003590A2 (pt) 2016-05-31
EP2605771B1 (en) 2018-04-04
JP5938407B2 (ja) 2016-06-22
KR20190097323A (ko) 2019-08-20
KR101847669B1 (ko) 2018-05-24
KR20130108301A (ko) 2013-10-02
CN103153296A (zh) 2013-06-12
PT2605771T (pt) 2018-07-09
JP2013534246A (ja) 2013-09-02
EP2605771A1 (en) 2013-06-26
JP2016117781A (ja) 2016-06-30
WO2012024161A1 (en) 2012-02-23
RU2016134989A (ru) 2018-12-11
US20140066483A1 (en) 2014-03-06
JP6250728B2 (ja) 2017-12-20
JP2018027984A (ja) 2018-02-22
DK2605771T3 (en) 2018-07-16
ES2676194T3 (es) 2018-07-17
CN103153296B (zh) 2018-02-13

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