HK1256207A1 - 用於增強檢測和分析物定量的系統及方法 - Google Patents

用於增強檢測和分析物定量的系統及方法

Info

Publication number
HK1256207A1
HK1256207A1 HK18115307.6A HK18115307A HK1256207A1 HK 1256207 A1 HK1256207 A1 HK 1256207A1 HK 18115307 A HK18115307 A HK 18115307A HK 1256207 A1 HK1256207 A1 HK 1256207A1
Authority
HK
Hong Kong
Prior art keywords
analytes
quantification
systems
methods
enhanced detection
Prior art date
Application number
HK18115307.6A
Other languages
English (en)
Inventor
Ayub Khattak
Clinton Sever
Paul Nelson
Ryan Cooper
Thomas Congdon
Justin Demartino
Raphael Shapiro
Mark Duncan
Original Assignee
Cue Health Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cue Health Inc filed Critical Cue Health Inc
Publication of HK1256207A1 publication Critical patent/HK1256207A1/zh

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0098—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/0045—Devices for taking samples of body liquids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02—Instruments for taking cell samples or for biopsy
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5023—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures with a sample being transported to, and subsequently stored in an absorbent for analysis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502723—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by venting arrangements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502738—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5029—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures using swabs
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/52—Containers specially adapted for storing or dispensing a reagent
    • B01L3/523—Containers specially adapted for storing or dispensing a reagent with means for closing or opening
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/52—Containers specially adapted for storing or dispensing a reagent
    • B01L3/527—Containers specially adapted for storing or dispensing a reagent for a plurality of reagents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00—Containers or packages with special means for dispensing contents
    • B65D83/0005—Containers or packages provided with a piston or with a movable bottom or partition having approximately the same section as the container
    • B65D83/005—Containers or packages provided with a piston or with a movable bottom or partition having approximately the same section as the container the piston or movable bottom being pulled upwards to dispense the contents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00—Containers or packages with special means for dispensing contents
    • B65D83/04—Containers or packages with special means for dispensing contents for dispensing annular, disc-shaped, or spherical or like small articles, e.g. tablets or pills
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00—Containers or packages with special means for dispensing contents
    • B65D83/08—Containers or packages with special means for dispensing contents for dispensing thin flat articles in succession
    • B65D83/0805—Containers or packages with special means for dispensing contents for dispensing thin flat articles in succession through an aperture in a wall
    • B65D83/0811—Containers or packages with special means for dispensing contents for dispensing thin flat articles in succession through an aperture in a wall with means for assisting dispensing
    • B65D83/0817—Containers or packages with special means for dispensing contents for dispensing thin flat articles in succession through an aperture in a wall with means for assisting dispensing the articles being automatically urged towards the dispensing aperture, e.g. spring-loaded
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00—Containers or packages with special means for dispensing contents
    • B65D83/08—Containers or packages with special means for dispensing contents for dispensing thin flat articles in succession
    • B65D83/0847—Containers or packages with special means for dispensing contents for dispensing thin flat articles in succession through an aperture at the junction of two walls
    • B65D83/0852—Containers or packages with special means for dispensing contents for dispensing thin flat articles in succession through an aperture at the junction of two walls with means for assisting dispensing
    • B65D83/0858—Containers or packages with special means for dispensing contents for dispensing thin flat articles in succession through an aperture at the junction of two walls with means for assisting dispensing the articles being automatically urged towards the dispensing aperture, e.g. spring-loaded
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00—Subject matter not provided for in other groups of this subclass
    • F16K99/0001—Microvalves
    • F16K99/0003—Constructional types of microvalves; Details of the cutting-off member
    • F16K99/0032—Constructional types of microvalves; Details of the cutting-off member using phase transition or influencing viscosity
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00—Subject matter not provided for in other groups of this subclass
    • F16K99/0001—Microvalves
    • F16K99/0034—Operating means specially adapted for microvalves
    • F16K99/0036—Operating means specially adapted for microvalves operated by temperature variations
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/10—Devices for withdrawing samples in the liquid or fluent state
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/34—Purifying; Cleaning
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/06—Investigating concentration of particle suspensions
    • G01N15/0606—Investigating concentration of particle suspensions by collecting particles on a support
    • G01N15/0618—Investigating concentration of particle suspensions by collecting particles on a support of the filter type
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/78—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
    • G01N27/3272—Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
    • G01N27/3273—Devices therefor, e.g. test element readers, circuitry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G01N33/54333—Modification of conditions of immunological binding reaction, e.g. use of more than one type of particle, use of chemical agents to improve binding, choice of incubation time or application of magnetic field during binding reaction
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G01N33/5438—Electrodes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/581—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with enzyme label (including co-enzymes, co-factors, enzyme inhibitors or substrates)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/00722—Communications; Identification
    • G01N35/00871—Communications between instruments or with remote terminals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/08—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a stream of discrete samples flowing along a tube system, e.g. flow injection analysis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1095—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices for supplying the samples to flow-through analysers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/157—Devices characterised by integrated means for measuring characteristics of blood
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/025—Align devices or objects to ensure defined positions relative to each other
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/026—Fluid interfacing between devices or objects, e.g. connectors, inlet details
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/026—Fluid interfacing between devices or objects, e.g. connectors, inlet details
    • B01L2200/027—Fluid interfacing between devices or objects, e.g. connectors, inlet details for microfluidic devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/028—Modular arrangements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/04—Exchange or ejection of cartridges, containers or reservoirs
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
    • B01L2200/0668—Trapping microscopic beads
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0684—Venting, avoiding backpressure, avoid gas bubbles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0689—Sealing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/08—Ergonomic or safety aspects of handling devices
    • B01L2200/087—Ergonomic aspects
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/14—Process control and prevention of errors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/16—Reagents, handling or storing thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/02—Identification, exchange or storage of information
    • B01L2300/023—Sending and receiving of information, e.g. using bluetooth
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/02—Identification, exchange or storage of information
    • B01L2300/025—Displaying results or values with integrated means
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/041—Connecting closures to device or container
    • B01L2300/044—Connecting closures to device or container pierceable, e.g. films, membranes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/046—Function or devices integrated in the closure
    • B01L2300/047—Additional chamber, reservoir
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0645—Electrodes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0663—Whole sensors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0672—Integrated piercing tool
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0681—Filter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/069—Absorbents; Gels to retain a fluid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0832—Geometry, shape and general structure cylindrical, tube shaped
    • B01L2300/0838—Capillaries
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0867—Multiple inlets and one sample wells, e.g. mixing, dilution
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/087—Multiple sequential chambers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/12—Specific details about materials
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/16—Surface properties and coatings
    • B01L2300/161—Control and use of surface tension forces, e.g. hydrophobic, hydrophilic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
    • B01L2300/1827—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using resistive heater
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0433—Moving fluids with specific forces or mechanical means specific forces vibrational forces
    • B01L2400/0439—Moving fluids with specific forces or mechanical means specific forces vibrational forces ultrasonic vibrations, vibrating piezo elements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0481—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure squeezing of channels or chambers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0677—Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0677—Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers
    • B01L2400/0683—Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers mechanically breaking a wall or membrane within a channel or chamber
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6825—Nucleic acid detection involving sensors
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00—Subject matter not provided for in other groups of this subclass
    • F16K2099/0082—Microvalves adapted for a particular use
    • F16K2099/0084—Chemistry or biology, e.g. "lab-on-a-chip" technology
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N2001/022—Devices for withdrawing samples sampling for security purposes, e.g. contraband, warfare agents
    • G01N2001/027—Devices for withdrawing samples sampling for security purposes, e.g. contraband, warfare agents field kits / quick test kits
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N2001/028—Sampling from a surface, swabbing, vaporising
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00178—Special arrangements of analysers
    • G01N2035/00277—Special precautions to avoid contamination (e.g. enclosures, glove- boxes, sealed sample carriers, disposal of contaminated material)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00465—Separating and mixing arrangements
    • G01N2035/00534—Mixing by a special element, e.g. stirrer
    • G01N2035/00554—Mixing by a special element, e.g. stirrer using ultrasound
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00465—Separating and mixing arrangements
    • G01N2035/00564—Handling or washing solid phase elements, e.g. beads
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/00722—Communications; Identification
    • G01N2035/00891—Displaying information to the operator
    • G01N2035/0091—GUI [graphical user interfaces]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2458/00—Labels used in chemical analysis of biological material
    • G01N2458/30—Electrochemically active labels
HK18115307.6A 2015-07-17 2018-11-29 用於增強檢測和分析物定量的系統及方法 HK1256207A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562194101P 2015-07-17 2015-07-17
PCT/US2016/042688 WO2017015172A1 (en) 2015-07-17 2016-07-16 Systems and methods for enhanced detection and quantification of analytes

Publications (1)

Publication Number Publication Date
HK1256207A1 true HK1256207A1 (zh) 2019-09-13

Family

ID=56551013

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18115307.6A HK1256207A1 (zh) 2015-07-17 2018-11-29 用於增強檢測和分析物定量的系統及方法

Country Status (11)

Country Link
US (10) US9718058B2 (zh)
EP (2) EP3689466A1 (zh)
JP (7) JP6824953B2 (zh)
KR (2) KR102604091B1 (zh)
CN (4) CN117310193A (zh)
AU (3) AU2016296589B2 (zh)
BR (2) BR112018000851B1 (zh)
CA (3) CA3224549A1 (zh)
HK (1) HK1256207A1 (zh)
WO (1) WO2017015172A1 (zh)
ZA (2) ZA201800856B (zh)

Families Citing this family (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102358124B1 (ko) 2013-03-11 2022-02-08 큐 헬스 인코퍼레이티드 분석물의 검출 및 정량을 위한 시스템 및 방법
US9623409B2 (en) 2013-03-11 2017-04-18 Cue Inc. Cartridges, kits, and methods for enhanced mixing for detection and quantification of analytes
US10545161B2 (en) 2013-03-11 2020-01-28 Cue Health Inc. Systems and methods for detection and quantification of analytes
WO2015164770A1 (en) 2014-04-24 2015-10-29 Diassess Inc. Colorimetric detection of nucleic acid amplification
USD745423S1 (en) 2014-05-12 2015-12-15 Cue Inc. Automated analyzer test cartridge and sample collection device for analyte detection
US9623415B2 (en) 2014-12-31 2017-04-18 Click Diagnostics, Inc. Devices and methods for molecular diagnostic testing
CN117310193A (zh) 2015-07-17 2023-12-29 克忧健康公司 用于增强检测和分析物定量的系统及方法
EP3754011B1 (en) 2015-09-09 2022-02-16 Drawbridge Health, Inc. Devices for sample collection, stabilization and preservation
CA3005084A1 (en) * 2015-12-11 2017-06-15 Opko Diagnostics, Llc Fluidic systems involving incubation of samples and/or reagents
CA3015376C (en) 2016-03-14 2023-11-14 Diassess Inc. Devices and methods for biological assay sample preparation and delivery
CA3015368A1 (en) 2016-03-14 2017-09-21 Diassess Inc. Systems and methods for performing biological assays
JP2019509740A (ja) 2016-03-14 2019-04-11 ディアスセス インコーポレイテッド 選択的に通気される生物学的アッセイ装置および関連の方法
WO2017185067A1 (en) 2016-04-22 2017-10-26 Click Diagnostics, Inc. Printed circuit board heater for an amplification module
US11002737B2 (en) * 2016-09-29 2021-05-11 Worcester Polytechnic Institute Micro-array devices for capturing cells in blood and methods of their use
JP1754773S (ja) 2017-01-10 2023-10-06 サンプル採取器具
US11237161B2 (en) 2017-01-25 2022-02-01 Cue Health Inc. Systems and methods for enhanced detection and quantification of analytes
KR20180091175A (ko) * 2017-02-06 2018-08-16 삼성전자주식회사 유체분석 카트리지 및 이를 포함하는 유체분석 카트리지 어셈블리
US11080848B2 (en) 2017-04-06 2021-08-03 Lucira Health, Inc. Image-based disease diagnostics using a mobile device
WO2019017912A1 (en) 2017-07-18 2019-01-24 Hewlett-Packard Development Company, L.P. DEVICES AND METHODS OF TEST SAMPLES
CA3070455A1 (en) * 2017-07-19 2019-01-24 Evanostics, Llc Cartridges for oral fluid analysis and methods of use
US10549275B2 (en) 2017-09-14 2020-02-04 Lucira Health, Inc. Multiplexed biological assay device with electronic readout
EP3724636A4 (en) 2017-12-15 2021-08-18 Evanostics, LLC OPTICAL READER FOR ANALYTE TEST
EP3731959A4 (en) 2017-12-29 2021-10-13 Clear Labs Inc. AUTOMATED PRIMING AND LIBRARY LOADER
CA3105374C (en) 2018-06-29 2022-08-23 Siemens Healthcare Diagnostics Inc. Sensor assembly for a sample fluid analysis system
CN110954759B (zh) * 2018-09-27 2022-08-02 湖南嘉业达电子有限公司 压电相变点在生产过程中的评测装置
CA3199825A1 (en) * 2018-11-02 2020-02-07 Cardiai Technologies Ltd. Portable electrochemical-sensor system for analyzing user health conditions and method thereof
USD915592S1 (en) * 2019-01-18 2021-04-06 Nico Corporation Dissection device
GB2580964B (en) 2019-02-01 2023-06-07 Dnae Diagnostics Ltd Storage Device
KR102104741B1 (ko) * 2019-02-15 2020-06-01 국민대학교산학협력단 슬라이딩 방식의 교체형 유체 분석 챔버 모듈
CN110057652B (zh) * 2019-04-25 2024-01-12 壹妙芯(厦门)科技有限公司 一种生物样品采集装置
USD918390S1 (en) * 2019-06-13 2021-05-04 Prodont Holliger Handle for hand-held dental instruments
CN112295628A (zh) * 2019-08-01 2021-02-02 利多(香港)有限公司 试剂的保存方法
EP4028353A4 (en) * 2019-09-09 2024-01-24 Lumacyte LLC MICROFLUIDIC DEVICES AND METHOD FOR SAMPLING AND ANALYZING CELLS USING OPTICAL FORCES AND RAMAN SPECTROSCOPY
US11352675B2 (en) 2020-01-03 2022-06-07 Visby Medical, Inc. Devices and methods for antibiotic susceptability testing
US20210292855A1 (en) * 2020-03-17 2021-09-23 Detect, Inc. Downloadable software application for guiding a rapid test
EP4128247A4 (en) * 2020-03-27 2024-05-01 Salvus Llc SYSTEM AND METHOD FOR ANALYTE MONITORING AND PREDICTIVE MODELING
WO2021226145A1 (en) * 2020-05-04 2021-11-11 Biotex, Inc. Methods and devices for pathogen detection
USD953561S1 (en) 2020-05-05 2022-05-31 Lucira Health, Inc. Diagnostic device with LED display
US20230211338A1 (en) * 2020-05-15 2023-07-06 Abacuslabs Ltd. A point of care device
USD962470S1 (en) 2020-06-03 2022-08-30 Lucira Health, Inc. Assay device with LCD display
JP1695257S (zh) * 2020-06-17 2021-09-21
JP1695258S (zh) * 2020-09-02 2021-09-21
JP1695260S (zh) * 2020-09-02 2021-09-21
JP1695261S (zh) * 2020-09-03 2021-09-21
EP4139055A4 (en) * 2020-09-03 2024-04-24 Illumina Inc CARTRIDGES AND ASSOCIATED SYSTEMS AND METHODS
CN114317250A (zh) * 2020-09-30 2022-04-12 富佳生技股份有限公司 加热结构、检测芯片、核酸检测盒及核酸检测设备
EP3978125A1 (en) * 2020-09-30 2022-04-06 iCare Diagnostics International Co. Ltd. Nucleic acid detection kit and nucleic acid detection device
US11852643B2 (en) * 2020-10-13 2023-12-26 Bionime Corporation Physiological signal monitoring device
CN112304933B (zh) * 2020-11-03 2021-09-21 南通市第一人民医院 一种智能消毒液比色显示控制方法及系统
WO2022101624A1 (en) * 2020-11-10 2022-05-19 Lumiradx Uk Ltd System for detection of a target in a liquid sample
USD970000S1 (en) * 2021-03-12 2022-11-15 Augusta University Research Institute, Inc. Swab
WO2023006817A1 (en) * 2021-07-28 2023-02-02 Bioeclosion, S.L. Device for assay system, system and method
CN114044241B (zh) * 2021-12-08 2023-06-09 广西科健邦生物技术有限公司 一种稳定性好的前白蛋白测定试剂盒
WO2023177684A1 (en) * 2022-03-15 2023-09-21 Cue Health Inc. Sample collection device
US20230304957A1 (en) * 2022-03-22 2023-09-28 Analog Devices International Unlimited Company Reference electrodes of electrochemical sensors
CN114397168B (zh) * 2022-03-28 2022-06-17 江西汉氏医学发展有限公司 基于互联网的体液平衡智能健康检测设备及检测方法
WO2023212070A2 (en) * 2022-04-29 2023-11-02 3Eo Health Inc. Swab assemblies and assay systems
WO2024020697A1 (en) * 2022-07-29 2024-02-01 Cardiai Technologies Ltd. Magnetic bead elisa detector device and methods of use thereof

Family Cites Families (211)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US843573A (en) 1905-09-07 1907-02-12 Axel Linus Blomen Air-gun.
CA159365A (en) 1914-01-01 1914-02-01 William H. Miner Draft rigging for railway cars
CA165985A (en) 1915-08-07 1915-11-09 William James Fullerton Car
US3915806A (en) 1974-01-17 1975-10-28 Denver Chemical Manufacturing Specimen holding kit
USD249062S (en) 1977-09-15 1978-08-22 Norabel Ab Dental instrument
US4381292A (en) 1980-11-14 1983-04-26 The Board Of Trustees Of The Leland Stanford Jr. University Anti-human T-lymphocyte monoclonal antibody
US4451570A (en) 1981-03-26 1984-05-29 The Regents Of The University Of California Immunoglobulin-secreting human hybridomas from a cultured human lymphoblastoid cell line
US4618577A (en) 1983-02-09 1986-10-21 The Regents Of The University Of California Human-human hybridoma, CLNH5
USD298166S (en) 1986-02-10 1988-10-18 Physio-Control Corporation Central hospital monitor
USD303288S (en) 1986-09-12 1989-09-05 Ballobes Aps Intragastric balloon kit consisting of an intragastric balloon device, a pump, a container tube and a box
USD302585S (en) 1987-05-14 1989-08-01 Elliott Raymond D Dental delivery unit
USD306067S (en) 1987-11-25 1990-02-13 Bogdanoff Steven P Dental implant cleaning tool
US5223414A (en) 1990-05-07 1993-06-29 Sri International Process for nucleic acid hybridization and amplification
US5273881A (en) 1990-05-07 1993-12-28 Daikin Industries, Ltd. Diagnostic applications of double D-loop formation
USD343679S (en) 1990-10-31 1994-01-25 Evergreen Industries, Inc. Inoculation streaker
US5455166A (en) 1991-01-31 1995-10-03 Becton, Dickinson And Company Strand displacement amplification
US5178298A (en) 1992-02-12 1993-01-12 Allina Curtis J Candy dispenser
US5498392A (en) 1992-05-01 1996-03-12 Trustees Of The University Of Pennsylvania Mesoscale polynucleotide amplification device and method
US5714320A (en) 1993-04-15 1998-02-03 University Of Rochester Rolling circle synthesis of oligonucleotides and amplification of select randomized circular oligonucleotides
US5470723A (en) 1993-05-05 1995-11-28 Becton, Dickinson And Company Detection of mycobacteria by multiplex nucleic acid amplification
USD379230S (en) 1994-10-28 1997-05-13 Phillip Mark Droplet liquid applicator brush
US6207369B1 (en) 1995-03-10 2001-03-27 Meso Scale Technologies, Llc Multi-array, multi-specific electrochemiluminescence testing
JPH11514849A (ja) * 1995-07-12 1999-12-21 チャーム サイエンシズ インコーポレイテッド 検査サンプルを検出するための検査装置、システム及び方法
US5708247A (en) 1996-02-14 1998-01-13 Selfcare, Inc. Disposable glucose test strips, and methods and compositions for making same
US5935804A (en) 1997-03-21 1999-08-10 Laine; Roger A. Method for detecting eubacteria in biological samples with catalytically inactive murein binding enzymes
US6413783B1 (en) 1997-09-18 2002-07-02 Meso Scale Technologies, Llc Assay sonication apparatus and methodology
USD402753S (en) 1997-11-19 1998-12-15 White Theresa M Medication consumption aid
CA2312102C (en) * 1997-12-24 2007-09-04 Cepheid Integrated fluid manipulation cartridge
US6248294B1 (en) 1998-04-15 2001-06-19 Frederic L. Nason Self contained diagnostic test unit
US6153148A (en) * 1998-06-15 2000-11-28 Becton, Dickinson And Company Centrifugal hematology disposable
US6146590A (en) 1998-06-29 2000-11-14 Mainline Technology, Inc. Vessel for an analytic test device
US6558320B1 (en) * 2000-01-20 2003-05-06 Medtronic Minimed, Inc. Handheld personal data assistant (PDA) with a medical device and method of using the same
US6523560B1 (en) 1998-09-03 2003-02-25 General Electric Corporation Microvalve with pressure equalization
US6235502B1 (en) 1998-09-18 2001-05-22 Molecular Staging Inc. Methods for selectively isolating DNA using rolling circle amplification
DE1020534T1 (de) 1998-11-09 2001-03-01 Eiken Chemical Verfahren zur synthetisieren von nukleinsäure
US7914994B2 (en) 1998-12-24 2011-03-29 Cepheid Method for separating an analyte from a sample
AUPP915799A0 (en) 1999-03-11 1999-04-15 Enterix Inc. Sample collection and testing system
JP2000346838A (ja) * 1999-03-30 2000-12-15 Kikkoman Corp 検体検査用器具及び拭取検査用器具
FR2791697B1 (fr) 1999-04-01 2003-02-28 Biomerieux Sa Appareil et procede de lyse par ultrasons de cellules biologiques
US6942771B1 (en) 1999-04-21 2005-09-13 Clinical Micro Sensors, Inc. Microfluidic systems in the electrochemical detection of target analytes
US20020177135A1 (en) 1999-07-27 2002-11-28 Doung Hau H. Devices and methods for biochip multiplexing
ES2158808B1 (es) 1999-10-15 2002-04-01 Consejo Superior Investigacion Sistema electromagnetico para la manipulacion de fluidos.
US6514415B2 (en) 2000-01-31 2003-02-04 Dexter Magnetic Technologies, Inc. Method and apparatus for magnetic separation of particles
US20010046687A1 (en) 2000-03-31 2001-11-29 Dicesare Joseph L. Method for the enhancement of luminescence intensity from a reaction between adenosine triphosphate (ATP) and a luciferase/luciferin reactant system
CA2407973C (en) 2000-05-03 2011-06-07 Jen-Jr Gau Biological identification system with integrated sensor chip
USD458456S1 (en) 2001-03-26 2002-06-11 Centrix, Inc. Double ended applicator
US6852287B2 (en) 2001-09-12 2005-02-08 Handylab, Inc. Microfluidic devices having a reduced number of input and output connections
US6575188B2 (en) 2001-07-26 2003-06-10 Handylab, Inc. Methods and systems for fluid control in microfluidic devices
CA2444649C (en) 2001-04-20 2012-10-02 The Penn State Research Foundation Methods for nucleic acid manipulation
EP1277438A1 (en) 2001-07-10 2003-01-22 Agilent Technologies, Inc. (a Delaware corporation) System for point of care diagnosis and/or analysis
US7285412B2 (en) 2001-07-27 2007-10-23 Surface Logix Inc. Device for magnetic immobilization of cells
WO2003025559A1 (fr) 2001-09-11 2003-03-27 Arkray, Inc. Instrument de mesure, corps d'installation et mesureur de densite
US7879293B2 (en) 2001-09-28 2011-02-01 Orasure Technologies, Inc. Sample collector and test device
USD472975S1 (en) 2001-10-18 2003-04-08 International Reagents Corporation Container for receiving specimen
US7399590B2 (en) 2002-02-21 2008-07-15 Asm Scientific, Inc. Recombinase polymerase amplification
WO2003103485A1 (ja) 2002-06-07 2003-12-18 プレシジョン・システム・サイエンス株式会社 携帯端末装置、および、生活習慣病患者−医療機関連携システム
US20040011650A1 (en) 2002-07-22 2004-01-22 Frederic Zenhausern Method and apparatus for manipulating polarizable analytes via dielectrophoresis
KR100480338B1 (ko) 2002-08-08 2005-03-30 한국전자통신연구원 극소량의 유체제어를 위한 미세 유체제어소자
US6910797B2 (en) 2002-08-14 2005-06-28 Hewlett-Packard Development, L.P. Mixing device having sequentially activatable circulators
GB2391813B (en) 2002-08-14 2006-03-29 Cozart Bioscience Ltd An oral fluid collection, transfer and transportation device and method
DE10237931A1 (de) 2002-08-14 2004-02-26 Endress + Hauser Gmbh + Co. Kg Vorrichtung zur Überwachung eines vorbestimmten Füllstands eines Messmediums in einem Behälter
US8158695B2 (en) 2002-09-06 2012-04-17 Johnson & Johnson Vision Care, Inc. Forming clear, wettable silicone hydrogel articles without surface treatments
WO2004027025A2 (en) 2002-09-20 2004-04-01 New England Biolabs, Inc. Helicase dependent amplification of nucleic acids
US7195036B2 (en) 2002-11-04 2007-03-27 The Regents Of The University Of Michigan Thermal micro-valves for micro-integrated devices
US7238520B2 (en) 2002-12-04 2007-07-03 Smiths Detection Inc. PCR sample preparation holder and method
CA3122193A1 (en) 2002-12-26 2004-07-22 Meso Scale Technologies, Llc. Assay cartridges and methods of using the same
US7820030B2 (en) 2003-04-16 2010-10-26 Handylab, Inc. System and method for electrochemical detection of biological compounds
US7517494B2 (en) * 2003-04-30 2009-04-14 Hewlett-Packard Development Company, L.P. Test tray and test system for determining response of a biological sample
US7435381B2 (en) 2003-05-29 2008-10-14 Siemens Healthcare Diagnostics Inc. Packaging of microfluidic devices
US7723099B2 (en) * 2003-09-10 2010-05-25 Abbott Point Of Care Inc. Immunoassay device with immuno-reference electrode
KR101330431B1 (ko) 2003-09-11 2013-11-20 테라노스, 인코포레이티드 피분석물의 모니터링 및 약물 전달을 위한 의료 기기
US6991898B2 (en) 2003-10-20 2006-01-31 Kimberly-Clark Worldwide, Inc. Diagnostic test device and method of using same
US7943089B2 (en) 2003-12-19 2011-05-17 Kimberly-Clark Worldwide, Inc. Laminated assay devices
US7098040B2 (en) 2003-12-23 2006-08-29 Kimberly-Clark Worldwide, Inc. Self-contained swab-based diagnostic systems
US20050178700A1 (en) 2004-01-21 2005-08-18 David Tyvoll Sorting particles in parallel
US7628787B2 (en) 2004-02-03 2009-12-08 Covidien Ag Self contained, gas-enhanced surgical instrument
US7432106B2 (en) * 2004-03-24 2008-10-07 Applied Biosystems Inc. Liquid processing device including gas trap, and system and method
US7466908B1 (en) 2004-04-16 2008-12-16 Spartan Bioscience Inc. System for rapid nucleic acid amplification and detection
US7118667B2 (en) 2004-06-02 2006-10-10 Jin Po Lee Biosensors having improved sample application and uses thereof
JP2006007146A (ja) 2004-06-28 2006-01-12 Canon Inc 粒子分離装置
JP4319590B2 (ja) 2004-07-12 2009-08-26 アルフレッサファーマ株式会社 採便容器
JP2008513022A (ja) 2004-09-15 2008-05-01 マイクロチップ バイオテクノロジーズ， インコーポレイテッド マイクロ流体デバイス
USD518597S1 (en) 2004-12-08 2006-04-04 Sommers J Erich Lotion applicator
US8883487B2 (en) 2004-12-23 2014-11-11 Abbott Point Of Care Inc. Molecular diagnostics system and methods
JP2008528170A (ja) 2005-01-31 2008-07-31 ギブン・イメージング・リミテツド 生体内分析用デバイス、装置および方法
WO2006084472A1 (en) * 2005-02-10 2006-08-17 Chempaq A/S Dual sample cartridge and method for characterizing particle in liquid
US7981696B2 (en) 2005-02-18 2011-07-19 The United States of America, as represented by the Secretary of Commerce, The National Institute of Standards and Technology Microfluidic platform of arrayed switchable spin-valve elements for high-throughput sorting and manipulation of magnetic particles and biomolecules
USD542931S1 (en) 2005-03-31 2007-05-15 Roche Diagnostics Operations, Inc. Laboratory measuring device housing
KR100668335B1 (ko) 2005-04-02 2007-01-12 삼성전자주식회사 자성 왁스 플러그를 구비한 마이크로 밸브 및 자성 왁스를이용한 유동 제어 방법
US20060243591A1 (en) 2005-04-28 2006-11-02 Plotkin Elliot V Electrochemical-based analytical test strip with hydrophilicity enhanced metal electrodes
WO2006121510A2 (en) 2005-05-09 2006-11-16 Theranos, Inc. Point-of-care fluidic systems and uses thereof
EP1915618A4 (en) 2005-06-02 2009-09-30 Fluidigm Corp ANALYSIS USING MICROFLUIDIC SEPARATION DEVICES
WO2007002579A2 (en) 2005-06-23 2007-01-04 Bioveris Corporation Assay cartridges and methods for point of care instruments
TW200714898A (en) 2005-08-02 2007-04-16 3M Innovative Properties Co Apparatus and method for detecting an analyte
US8005526B2 (en) 2005-08-31 2011-08-23 The Regents Of The University Of Michigan Biologically integrated electrode devices
CN101300352B (zh) * 2005-09-01 2013-03-20 佳能美国生命科学公司 检测、分析和鉴定基因组dna的方法和分子诊断装置
GB0518652D0 (en) * 2005-09-13 2005-10-19 Inverness Medical Switzerland Device
EP1945815A4 (en) * 2005-10-11 2009-02-18 Handylab Inc DEVICE FOR PREPARING SAMPLE OF POLYNUCLEOTIDES
CA2634735A1 (en) 2005-12-29 2007-07-12 I-Stat Corporation Molecular diagnostics amplification system and methods
US20070299364A1 (en) 2006-06-22 2007-12-27 Sangha Jangbir S Containerized sample collection apparatus and method
US7976795B2 (en) * 2006-01-19 2011-07-12 Rheonix, Inc. Microfluidic systems
US20090061450A1 (en) 2006-03-14 2009-03-05 Micronics, Inc. System and method for diagnosis of infectious diseases
US8741230B2 (en) 2006-03-24 2014-06-03 Theranos, Inc. Systems and methods of sample processing and fluid control in a fluidic system
US7998708B2 (en) 2006-03-24 2011-08-16 Handylab, Inc. Microfluidic system for amplifying and detecting polynucleotides in parallel
US8088616B2 (en) 2006-03-24 2012-01-03 Handylab, Inc. Heater unit for microfluidic diagnostic system
DK2001990T3 (en) 2006-03-24 2016-10-03 Handylab Inc Integrated microfluidic sample processing system and method for its use
GB2436616A (en) 2006-03-29 2007-10-03 Inverness Medical Switzerland Assay device and method
US9063132B2 (en) 2006-03-29 2015-06-23 Inverness Medical Switzerland Gmbh Assay device and method
AU2007298650B2 (en) 2006-05-04 2013-10-17 Abbott Diagnostics Scarborough, Inc. Recombinase polymerase amplification
US8007999B2 (en) 2006-05-10 2011-08-30 Theranos, Inc. Real-time detection of influenza virus
US8008034B2 (en) 2006-10-13 2011-08-30 Theranos, Inc. Reducing optical interference in a fluidic device
US8012744B2 (en) 2006-10-13 2011-09-06 Theranos, Inc. Reducing optical interference in a fluidic device
US7807454B2 (en) 2006-10-18 2010-10-05 The Regents Of The University Of California Microfluidic magnetophoretic device and methods for using the same
US20080113391A1 (en) 2006-11-14 2008-05-15 Ian Gibbons Detection and quantification of analytes in bodily fluids
US8157730B2 (en) 2006-12-19 2012-04-17 Valencell, Inc. Physiological and environmental monitoring systems and methods
US7993525B2 (en) * 2006-12-29 2011-08-09 Intel Corporation Device and method for particle complex handling
US8409877B2 (en) 2006-12-29 2013-04-02 Intel Corporation Enzymatic signal generation and detection of binding complexes in stationary fluidic chip
US7863035B2 (en) * 2007-02-15 2011-01-04 Osmetech Technology Inc. Fluidics devices
WO2008122908A1 (en) * 2007-04-04 2008-10-16 Koninklijke Philips Electronics N.V. Method and device for gathering a fluid sample for screening purposes
US8186913B2 (en) 2007-04-16 2012-05-29 The General Hospital Corporation Systems and methods for particle focusing in microchannels
CA2587198A1 (en) 2007-05-02 2008-11-02 Spartan Bioscience Inc. Method for increasing the speed of nucleic acid amplification reactions
ES2687620T3 (es) 2007-05-04 2018-10-26 Opko Diagnostics, Llc Dispositivo y método para análisis en sistemas microfluídicos
WO2008152980A1 (ja) * 2007-06-12 2008-12-18 Olympus Corporation 生物学的試料と試薬との混合用容器及び生物学的試料と試薬との混合方法
EP2171420A1 (en) * 2007-07-31 2010-04-07 Micronics, Inc. Sanitary swab collection system, microfluidic assay device, and methods for diagnostic assays
GB0715171D0 (en) 2007-08-03 2007-09-12 Enigma Diagnostics Ltd Sample processor
US8158430B1 (en) 2007-08-06 2012-04-17 Theranos, Inc. Systems and methods of fluidic sample processing
WO2009034563A2 (en) 2007-09-14 2009-03-19 Nanocomms Patents Limited An analysis system
JP5584954B2 (ja) 2007-09-27 2014-09-10 富士通株式会社 被検体評価方法
SG188082A1 (en) 2007-10-02 2013-03-28 Theranos Inc Modular point-of-care devices and uses thereof
EP2050498A1 (en) 2007-10-19 2009-04-22 Koninklijke Philips Electronics N.V. Fluid handling device for analysis of fluid samples
USD591864S1 (en) 2007-12-10 2009-05-05 Dako Denmark A/S Housing for a biological sample processing apparatus
CN101464412B (zh) 2007-12-19 2011-06-29 中国科学院电子学研究所 光学快速检测表面洁净度用生物传感器及测试方法
EP2250503A2 (en) 2008-02-20 2010-11-17 3M Innovative Properties Company Methods of analyzing samples for bacteria using whole cell capture and atp analysis
KR20170138578A (ko) 2008-03-26 2017-12-15 테라노스, 인코포레이티드 임상 결과를 평가하기 위한 방법 및 시스템
USD600578S1 (en) 2008-04-02 2009-09-22 Daikin Industries Ltd. Bacteria measuring instrument
WO2010003212A1 (en) 2008-07-11 2010-01-14 Early Warning Inc. Biosensing device and method for detecting target biomolecules in a solution
CA2638458A1 (en) 2008-07-31 2010-01-31 Spartan Bioscience Inc. Thermal recycling by positioning relative to fixed-temperature source
ES2340753B1 (es) 2008-09-04 2011-08-03 Consejo Superior De Investigaciones Científicas (Csic) Biosensor para la deteccion de anticuerpos anti-vih.
EP2340301A4 (en) 2008-09-24 2012-05-09 Straus Holdings Inc IMAGING ANALYZER FOR ANALYTE TESTING
JP2012504956A (ja) * 2008-10-10 2012-03-01 セントレ ナショナル デ ラ レシェルシェ サイエンティフィーク−ディーエーイー 細胞ソート・デバイス
US8361808B2 (en) 2008-12-31 2013-01-29 Oranoxis, Inc. Capillary flow solid phase assay
WO2010078482A1 (en) * 2008-12-31 2010-07-08 3M Innovative Properties Company Live bioload detection using microparticles
WO2010087191A1 (ja) 2009-01-30 2010-08-05 パナソニック株式会社 生体試料の温度測定方法、生体試料の濃度測定方法、センサチップおよびバイオセンサシステム
EP2400895A2 (en) 2009-02-27 2012-01-04 Koninklijke Philips Electronics N.V. Connection system for sensor cartridge
US8449842B2 (en) 2009-03-19 2013-05-28 Thermo Scientific Portable Analytical Instruments Inc. Molecular reader
EP2409130B1 (en) 2009-03-20 2013-12-04 Pbs Biotech, Inc. Automatable aseptic sample withdrawal system
RU2011142784A (ru) 2009-03-23 2013-04-27 Конинклейке Филипс Электроникс Н.В. Манипуляция магнитными частицами в биологическом образце
CA2662546A1 (en) 2009-04-15 2010-10-15 Spartan Bioscience Inc. Tube for dna reactions
JP5146399B2 (ja) 2009-04-27 2013-02-20 横河電機株式会社 化学反応用カートリッジおよびその駆動機構
EP2430446A4 (en) 2009-05-11 2012-12-05 Nexus Dx Inc METHOD AND COMPOSITIONS FOR DETECTING ANALYTES
CN101893523A (zh) * 2009-05-20 2010-11-24 纳米基因有限公司 分析物检测的方法和组合物
WO2010140128A1 (en) 2009-06-03 2010-12-09 Koninklijke Philips Electronics N.V. Valve with material having modifiable degree of penetrability
EP3586945A3 (en) 2009-06-05 2020-03-04 IntegenX Inc. Universal sample preparation system and use in an integrated analysis system
US20100331652A1 (en) * 2009-06-29 2010-12-30 Roche Diagnostics Operations, Inc. Modular diabetes management systems
JP2011013043A (ja) 2009-06-30 2011-01-20 Beckman Coulter Inc 磁性粒子移送装置および磁性粒子移送方法
WO2011011172A1 (en) 2009-07-21 2011-01-27 IntegenX, Inc. Microfluidic devices and uses thereof
US8993346B2 (en) 2009-08-07 2015-03-31 Nanomix, Inc. Magnetic carbon nanotube based biodetection
US8481336B2 (en) 2009-09-09 2013-07-09 The Board Of Trustees Of The Leland Stanford Junior University Magnetic separation device for cell sorting and analysis
US20120180580A1 (en) 2009-09-21 2012-07-19 Koninklijke Philips Electronics N.V. Disposable cartridge and sample analyzer
AU2010308329B2 (en) 2009-10-19 2016-10-13 Labrador Diagnostics Llc Integrated health data capture and analysis system
WO2011071772A2 (en) 2009-12-07 2011-06-16 Meso Scale Technologies, Llc. Assay cartridges and methods of using the same
WO2011079110A1 (en) 2009-12-24 2011-06-30 Mikhail Briman Carbon-based electrodes with graphene modification
EP2519355B1 (en) * 2009-12-30 2017-01-25 3M Innovative Properties Company Live bioload detection using microparticles
USD679025S1 (en) 2010-01-22 2013-03-26 Biotix, Inc. Anti-static pipette tip tray
USD646189S1 (en) 2010-03-18 2011-10-04 Agilent Technologies, Inc. Liquid chromatograph
EP2553122B1 (en) 2010-03-31 2017-08-09 Spartan Bioscience Inc. Direct nucleic acid analysis
GB2483077A (en) 2010-08-25 2012-02-29 Concateno Uk Ltd Sample testing assay apparatus and method
GB201014805D0 (en) 2010-09-07 2010-10-20 Multi Sense Technologies Ltd Microfluidics based assay device
TW201217783A (en) 2010-09-15 2012-05-01 Mbio Diagnostics Inc System and method for detecting multiple molecules in one assay
US8431408B2 (en) 2010-10-15 2013-04-30 Roche Diagnostics Operations, Inc. Handheld diabetes managing device with light pipe for enhanced illumination
JP2012132897A (ja) 2010-11-30 2012-07-12 Shizuokaken Koritsu Daigaku Hojin 検体採取具及び検体採取キット
GB201102037D0 (en) 2011-02-07 2011-03-23 Multi Sense Technologies Ltd Microfluidics based assay device
JP5584151B2 (ja) 2011-02-23 2014-09-03 協立電機株式会社 微量物質検出装置
EP2693208B1 (en) 2011-03-28 2017-10-11 Panasonic Healthcare Holdings Co., Ltd. Device for measuring biological sample
EP2515112B1 (en) 2011-04-22 2015-08-12 Sysmex Corporation Method for electrochemically detecting analyte
JP5805989B2 (ja) 2011-04-26 2015-11-10 大塚電子株式会社 電気泳動移動度測定用セル並びにそれを用いた測定装置及び測定方法
US8614087B2 (en) * 2011-05-02 2013-12-24 Ibis Biosciences, Inc. Multiple-analyte assay device and system
US20120316077A1 (en) 2011-06-07 2012-12-13 Charles Greef System And Method For Detection And Analysis Of A Molecule In A Sample
DE102011106523A1 (de) 2011-07-04 2013-01-10 Giesecke & Devrient Gmbh Prüfgerät und Verfahren zur Kalibrierung eines Prüfgeräts
US8737971B2 (en) 2011-07-17 2014-05-27 Pieter Van Rooyen Universal personal diagnostics platform
US8475739B2 (en) 2011-09-25 2013-07-02 Theranos, Inc. Systems and methods for fluid handling
US8889424B2 (en) 2011-09-13 2014-11-18 Joel R. L. Ehrenkranz Device and method for performing a diagnostic test
US8435738B2 (en) 2011-09-25 2013-05-07 Theranos, Inc. Systems and methods for multi-analysis
US9417210B2 (en) 2011-09-30 2016-08-16 Pandora Genomics, LLC System, apparatus and method for evaluating samples or analytes using a point-of-care device
US9593369B2 (en) 2011-10-05 2017-03-14 Spartan Bioscience Inc. Direct nucleic acid analysis
US9709469B2 (en) 2011-11-11 2017-07-18 The Regents Of The University Of California Valveless microfluidic device
EP2779900B1 (de) 2011-11-14 2015-09-16 Roche Diagnostics GmbH Analaysegerät zum nachweis mindestens eines analyten in einer probe
US20130145591A1 (en) 2011-12-13 2013-06-13 Yu-Lin Chen Pressing disc for disassembling bearings
EP2825501A1 (en) 2012-03-13 2015-01-21 Piramal Enterprises Limited Biosensor having nanostrucured electrodes
CN104411406B (zh) 2012-03-16 2017-05-31 统计诊断与创新有限公司 具有集成传送模块的测试盒
GB2500658A (en) 2012-03-28 2013-10-02 Dna Electronics Ltd Biosensor device and system
US10132802B2 (en) 2012-04-17 2018-11-20 i-calQ, LLC Device for performing a diagnostic test and methods for use thereof
USD698036S1 (en) 2012-05-09 2014-01-21 Biochrom Ltd Cuvette
USD694422S1 (en) 2012-05-15 2013-11-26 Wellstat Diagnostics, Llc Diagnostic instrument and sample cassette combination
US20130317318A1 (en) 2012-05-25 2013-11-28 Qualcomm Incorporated Methods and devices for acquiring electrodermal activity
EP2864827A4 (en) 2012-06-20 2016-01-27 Spartan Bioscience Inc OPTICAL FIBER WITH GRILLE AND PARTICLE COATING
KR101352900B1 (ko) 2012-07-31 2014-01-23 주식회사 아이센스 조작성이 향상된 생화학 분석 카트리지
EP2912432B1 (en) * 2012-10-24 2018-07-04 Genmark Diagnostics Inc. Integrated multiplex target analysis
US20140322706A1 (en) * 2012-10-24 2014-10-30 Jon Faiz Kayyem Integrated multipelx target analysis
US8724833B1 (en) 2012-12-18 2014-05-13 Floyd Bell Inc. Piezoelectric audible signal with spring contacts and retaining and spacer ring
US9623409B2 (en) 2013-03-11 2017-04-18 Cue Inc. Cartridges, kits, and methods for enhanced mixing for detection and quantification of analytes
KR102358124B1 (ko) 2013-03-11 2022-02-08 큐 헬스 인코퍼레이티드 분석물의 검출 및 정량을 위한 시스템 및 방법
US10545161B2 (en) 2013-03-11 2020-01-28 Cue Health Inc. Systems and methods for detection and quantification of analytes
USD719666S1 (en) 2013-03-14 2014-12-16 Reametrix, Inc. Cell detection system with touchscreen
USD745185S1 (en) 2014-04-15 2015-12-08 Shimadzu Corporation Sample feeder
USD745423S1 (en) 2014-05-12 2015-12-15 Cue Inc. Automated analyzer test cartridge and sample collection device for analyte detection
EP2982436B1 (en) * 2014-08-04 2020-09-09 Skyla Corporation Hsinchu Science Park Branch Testing module for testing a sample
JP6823589B2 (ja) 2014-09-11 2021-02-03 キュー ヘルス インコーポレイテッド 被分析物の検出および定量のためのシステム
CN104232622B (zh) 2014-09-24 2016-09-14 中国人民解放军疾病预防控制所 一种用聚合酶螺旋反应恒温扩增核酸的方法及其应用
CN117310193A (zh) 2015-07-17 2023-12-29 克忧健康公司 用于增强检测和分析物定量的系统及方法
TWI585312B (zh) 2015-12-30 2017-06-01 上銀科技股份有限公司 感測器結構

Also Published As

Publication number Publication date
CA2992596C (en) 2023-08-22
JP2022160500A (ja) 2022-10-19
USD825772S1 (en) 2018-08-14
US20220016620A1 (en) 2022-01-20
CN111487423A (zh) 2020-08-04
BR112018000851A2 (pt) 2018-09-04
AU2016296589A1 (en) 2018-02-08
US9808804B2 (en) 2017-11-07
EP3325153B1 (en) 2020-03-18
AU2016296589B2 (en) 2021-11-18
US20180104682A1 (en) 2018-04-19
US9718058B2 (en) 2017-08-01
JP1629282S (zh) 2019-04-15
EP3325153A1 (en) 2018-05-30
JP6824953B2 (ja) 2021-02-03
USD821602S1 (en) 2018-06-26
AU2021257927A1 (en) 2021-12-02
US20170045508A1 (en) 2017-02-16
ZA201900856B (en) 2020-10-28
US9999889B2 (en) 2018-06-19
CN108136391A (zh) 2018-06-08
CN111487423B (zh) 2023-09-01
CA3159274A1 (en) 2017-01-26
US20170043335A1 (en) 2017-02-16
EP3689466A1 (en) 2020-08-05
US20170043342A1 (en) 2017-02-16
BR122020004273B1 (pt) 2022-11-29
JP7112535B2 (ja) 2022-08-03
CA3224549A1 (en) 2017-01-26
JP1630919S (zh) 2019-05-13
AU2023204147A1 (en) 2023-07-20
ZA201800856B (en) 2019-04-24
KR20180037985A (ko) 2018-04-13
KR20230165349A (ko) 2023-12-05
JP2018528407A (ja) 2018-09-27
USD909600S1 (en) 2021-02-02
WO2017015172A1 (en) 2017-01-26
AU2021257927B2 (en) 2023-12-21
KR102604091B1 (ko) 2023-11-22
BR112018000851B1 (pt) 2022-10-18
US9724691B2 (en) 2017-08-08
JP2021092570A (ja) 2021-06-17
CN108136391B (zh) 2021-01-26
CN112881730A (zh) 2021-06-01
JP1617207S (zh) 2018-11-05
US11154866B2 (en) 2021-10-26
JP1631307S (zh) 2019-05-13
US11059045B2 (en) 2021-07-13
US20170043334A1 (en) 2017-02-16
CN117310193A (zh) 2023-12-29
US20170045507A1 (en) 2017-02-16
CA2992596A1 (en) 2017-01-26
JP7455908B2 (ja) 2024-03-26

Similar Documents

Publication Publication Date Title
ZA201900856B (en) Systems and methods for enhanced detection and quantification of analytes
IL290168A (en) Systems and methods for the detection and measurement of analytes
HK1252804A1 (zh) 用於基於測序的變型檢測的方法和系統
IL267241A (en) System and methods for identifying ransomware
IL258804B (en) Systems and methods for adaptive detection - area of defects
GB201719634D0 (en) Systems and methods for determining point of interest
IL250521A0 (en) Method and system for detecting malware
HK1257694A1 (zh) 用於多重檢測生物標誌物的系統和方法
EP3366524A4 (en) Parking space detection method and device
GB201701494D0 (en) Roadway-crossing-anomaly detection system and method
HK1243489A1 (zh) 用於檢測分析物的方法和系統
GB2550077B (en) Apparatus and method for detection of corrosion
EP3292395A4 (en) Methods and systems for the detection of analytes
HK1250748A1 (zh) 檢測和定量次要變體的並行式方法
GB201718352D0 (en) Devices and methods for detection of biomarkers
HK1250778A1 (zh) 分析物檢測及其方法
PL3589742T3 (pl) Sposób wykrywania
ZA201704429B (en) Method and system for the detection of conductive objects
IL252923A0 (en) Sensing system and method for discrimination and analysis
GB2537569B (en) Location detecting system and location detecting method of the location detecting system
KR102402386B9 (ko) 두께 판단 방법, 장치 및 시스템
SG11201606778TA (en) Methods and systems for quantification without standard curves
GB201520622D0 (en) Analyte Detection device and method
GB201408537D0 (en) Means and method for detection of analytes
GB201510425D0 (en) Detection system and method