HK1252248A1 - 对治疗剂和疾病特异性抗原进行测序、确定、配对和验证的方法 - Google Patents
对治疗剂和疾病特异性抗原进行测序、确定、配对和验证的方法 Download PDFInfo
- Publication number
- HK1252248A1 HK1252248A1 HK18111487.7A HK18111487A HK1252248A1 HK 1252248 A1 HK1252248 A1 HK 1252248A1 HK 18111487 A HK18111487 A HK 18111487A HK 1252248 A1 HK1252248 A1 HK 1252248A1
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- Prior art keywords
- methods
- sequencing
- pairing
- determining
- therapeutic agents
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/005—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies constructed by phage libraries
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6811—Selection methods for production or design of target specific oligonucleotides or binding molecules
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6848—Nucleic acid amplification reactions characterised by the means for preventing contamination or increasing the specificity or sensitivity of an amplification reaction
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
- C12Q2563/185—Nucleic acid dedicated to use as a hidden marker/bar code, e.g. inclusion of nucleic acids to mark art objects or animals
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Analytical Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Toxicology (AREA)
- Virology (AREA)
- Cell Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Plant Pathology (AREA)
- Transplantation (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562153041P | 2015-04-27 | 2015-04-27 | |
| US62/153,041 | 2015-04-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1252248A1 true HK1252248A1 (zh) | 2019-05-24 |
Family
ID=57199815
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK18111487.7A HK1252248A1 (zh) | 2015-04-27 | 2016-04-27 | 对治疗剂和疾病特异性抗原进行测序、确定、配对和验证的方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US10982258B2 (https=) |
| EP (1) | EP3289082A4 (https=) |
| JP (2) | JP6894380B2 (https=) |
| CN (1) | CN107849560B (https=) |
| AU (1) | AU2016253964B2 (https=) |
| CA (1) | CA2983937A1 (https=) |
| HK (1) | HK1252248A1 (https=) |
| MX (1) | MX2017013471A (https=) |
| WO (1) | WO2016176322A1 (https=) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9951386B2 (en) | 2014-06-26 | 2018-04-24 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
| WO2015188839A2 (en) | 2014-06-13 | 2015-12-17 | Immudex Aps | General detection and isolation of specific cells by binding of labeled molecules |
| US9975122B2 (en) | 2014-11-05 | 2018-05-22 | 10X Genomics, Inc. | Instrument systems for integrated sample processing |
| JP6955487B2 (ja) | 2015-09-24 | 2021-10-27 | アブビトロ， エルエルシー | Ｈｉｖ抗体組成物および使用方法 |
| MX2018003534A (es) | 2015-09-25 | 2019-04-25 | Abvitro Llc | Proceso de alto rendimiento para identificacion de blanco de receptor de celula t de secuencias de receptor de celula t apareadas de manera natural. |
| WO2017197343A2 (en) | 2016-05-12 | 2017-11-16 | 10X Genomics, Inc. | Microfluidic on-chip filters |
| WO2017197338A1 (en) | 2016-05-13 | 2017-11-16 | 10X Genomics, Inc. | Microfluidic systems and methods of use |
| US11708574B2 (en) * | 2016-06-10 | 2023-07-25 | Myriad Women's Health, Inc. | Nucleic acid sequencing adapters and uses thereof |
| US10550429B2 (en) | 2016-12-22 | 2020-02-04 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
| US10011872B1 (en) | 2016-12-22 | 2018-07-03 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
| US10815525B2 (en) | 2016-12-22 | 2020-10-27 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
| KR102702552B1 (ko) | 2016-12-23 | 2024-09-03 | 비스테라, 인크. | 결합 폴리펩타이드 및 이의 제조 방법 |
| US12264411B2 (en) | 2017-01-30 | 2025-04-01 | 10X Genomics, Inc. | Methods and systems for analysis |
| EP4029939B1 (en) | 2017-01-30 | 2023-06-28 | 10X Genomics, Inc. | Methods and systems for droplet-based single cell barcoding |
| KR102550778B1 (ko) | 2017-05-26 | 2023-07-03 | 에이비비트로 엘엘씨 | 고-처리량 폴리뉴클레오타이드 라이브러리 시퀀싱 및 전사체 분석 |
| EP3664835B1 (en) | 2017-08-09 | 2024-10-23 | Juno Therapeutics, Inc. | Methods and compositions for preparing genetically engineered cells |
| MA50079A (fr) | 2017-09-07 | 2020-07-15 | Juno Therapeutics Inc | Procédés d'identification de caractéristiques cellulaires relatives à des réponses associées à une thérapie cellulaire |
| WO2019084538A1 (en) * | 2017-10-27 | 2019-05-02 | Board Of Regents, The University Of Texas System | TUMOR SPECIFIC ANTIBODIES, T CELL RECEPTORS AND METHODS OF IDENTIFICATION THEREOF |
| MA51184A (fr) | 2017-12-15 | 2020-10-21 | Juno Therapeutics Inc | Molécules de liaison à l'anti-cct5 et procédés d'utilisation associés |
| SG11202007686VA (en) | 2018-02-12 | 2020-09-29 | 10X Genomics Inc | Methods characterizing multiple analytes from individual cells or cell populations |
| WO2019217758A1 (en) | 2018-05-10 | 2019-11-14 | 10X Genomics, Inc. | Methods and systems for molecular library generation |
| WO2019241249A1 (en) * | 2018-06-11 | 2019-12-19 | The Brigham And Women's Hospital, Inc. | Single cell cloning approaches for biological studies |
| WO2019238939A1 (en) | 2018-06-15 | 2019-12-19 | F. Hoffmann-La Roche Ag | A system for identification of antigens recognized by t cell receptors expressed on tumor infiltrating lymphocytes |
| CN116298309B (zh) * | 2018-08-13 | 2024-04-02 | 根路径基因组学公司 | 成对的二分免疫受体多核苷酸的高通量克隆及其应用 |
| EP4219753A3 (en) * | 2018-10-19 | 2023-09-06 | Akoya Biosciences, Inc. | Detection of co-occurring receptor-coding nucleic acid segments |
| SG11202107976SA (en) | 2019-01-29 | 2021-08-30 | Juno Therapeutics Inc | Antibodies and chimeric antigen receptors specific for receptor tyrosine kinase like orphan receptor 1 (ror1) |
| WO2020206238A2 (en) | 2019-04-05 | 2020-10-08 | Rootpath Genomics, Inc. | Compositions and methods for t-cell receptor gene assembly |
| JP7725466B2 (ja) * | 2019-11-13 | 2025-08-19 | アムニクス ファーマシューティカルズ， インコーポレイテッド | バーコード化されたｘｔｅｎポリペプチドおよびその組成物、ならびにその作製および使用方法 |
| US12449419B1 (en) | 2020-02-12 | 2025-10-21 | 10X Genomics, Inc. | Methods for detecting binding of peptide-MHC monomers to T cells |
| CN111218502B (zh) * | 2020-04-23 | 2020-07-21 | 圣湘生物科技股份有限公司 | 提升qPCR检测性能的组合物、反应液、用途及方法 |
| KR20230024283A (ko) | 2020-05-13 | 2023-02-20 | 주노 쎄러퓨티크스 인코퍼레이티드 | 임상 반응과 관련된 특징을 식별하는 방법 및 이의 용도 |
| WO2022081643A2 (en) * | 2020-10-13 | 2022-04-21 | 10X Genomics, Inc. | Compositions and methods for generating recombinant antigen binding molecules from single cells |
| CN114464253B (zh) * | 2022-03-03 | 2023-03-10 | 予果生物科技（北京）有限公司 | 基于长读长测序进行实时病原检测的方法、系统和应用 |
| EP4519675A4 (en) * | 2022-05-03 | 2026-04-08 | 3T Biosciences Inc | T-LYMPHOCYTE TARGET DISCOVERY |
| WO2024015862A1 (en) * | 2022-07-13 | 2024-01-18 | 10X Genomics, Inc. | Methods for characterization of antigen-binding molecules from biological samples |
| JP2026510460A (ja) | 2023-03-13 | 2026-04-06 | エイチ．リー モフィット キャンサー センター アンド リサーチ インスティテュート インコーポレイテッド | 選択された腫瘍浸潤リンパ球の組成物ならびに関連するその生成及び使用方法 |
| GB2629157A (en) * | 2023-04-18 | 2024-10-23 | The Institute Of Cancer Res Royal Cancer Hospital | T cell receptor sequencing |
| WO2025080865A1 (en) | 2023-10-11 | 2025-04-17 | Turnstone Biologics Corp. | Combination of tumor infiltrating lymphocytes (til) and low dose radiation |
| WO2025096638A2 (en) | 2023-10-30 | 2025-05-08 | Turnstone Biologics Corp. | Genetically modified tumor infilitrating lymphocytes and methods of producing and using the same |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1990004648A1 (en) * | 1988-10-20 | 1990-05-03 | Alexander Alan Morley | Method for diagnosis of monoclonality in leukaemia and lymphoma |
| WO2005059176A1 (en) * | 2003-12-15 | 2005-06-30 | Institut Pasteur | Repertoire determination of a lymphocyte b population |
| US8268564B2 (en) * | 2007-09-26 | 2012-09-18 | President And Fellows Of Harvard College | Methods and applications for stitched DNA barcodes |
| EP2364368B1 (en) * | 2008-11-07 | 2014-01-15 | Sequenta, Inc. | Methods of monitoring conditions by sequence analysis |
| US10385391B2 (en) * | 2009-09-22 | 2019-08-20 | President And Fellows Of Harvard College | Entangled mate sequencing |
| WO2012106385A2 (en) * | 2011-01-31 | 2012-08-09 | Apprise Bio, Inc. | Methods of identifying multiple epitopes in cells |
| CN103732738A (zh) * | 2011-04-28 | 2014-04-16 | 小利兰斯坦福大学托管委员会 | 与样品相关的多核苷酸的鉴定 |
| AU2012309830B2 (en) | 2011-09-15 | 2017-03-30 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | T cell receptors recognizing HLA-A1- or HLA-Cw7-restricted mage |
| EP2768982A4 (en) | 2011-10-21 | 2015-06-03 | Adaptive Biotechnologies Corp | QUANTIFICATION OF ADAPTIVE IMMUNOCELL GENOMES IN A COMPLEX MIX OF CELLS |
| EP2861760B1 (en) | 2012-06-15 | 2020-01-01 | The Board of Regents of The University of Texas System | High throughput sequencing of multiple transcripts of a single cell |
| JP6513035B2 (ja) * | 2013-02-22 | 2019-05-15 | アダプティヴ バイオテクノロジーズ コーポレーション | 希少クロノタイプおよびその用途 |
| KR20150132479A (ko) * | 2013-03-15 | 2015-11-25 | 어댑티브 바이오테크놀로지스 코포레이션 | 복합 유전자 세트에서의 독특하게 태그되고 재배열된 적응 면역 수용체 유전자 |
| GB2525568B (en) | 2013-03-15 | 2020-10-14 | Abvitro Llc | Single cell barcoding for antibody discovery |
| KR102758333B1 (ko) | 2013-08-28 | 2025-01-23 | 벡톤 디킨슨 앤드 컴퍼니 | 대량의 동시 단일 세포 분석 |
| CN113307880B (zh) * | 2014-01-13 | 2025-07-04 | 希望之城公司 | 在Fc间隔物区中具有突变的嵌合抗原受体(CAR)及其使用方法 |
| EP3950944A1 (en) | 2014-09-15 | 2022-02-09 | AbVitro LLC | High-throughput nucleotide library sequencing |
| EP3253479B1 (en) * | 2015-02-04 | 2022-09-21 | The Regents of The University of California | Sequencing of nucleic acids via barcoding in discrete entities |
-
2016
- 2016-04-27 AU AU2016253964A patent/AU2016253964B2/en not_active Ceased
- 2016-04-27 CN CN201680039185.4A patent/CN107849560B/zh not_active Expired - Fee Related
- 2016-04-27 WO PCT/US2016/029556 patent/WO2016176322A1/en not_active Ceased
- 2016-04-27 EP EP16787061.7A patent/EP3289082A4/en not_active Withdrawn
- 2016-04-27 CA CA2983937A patent/CA2983937A1/en active Pending
- 2016-04-27 MX MX2017013471A patent/MX2017013471A/es unknown
- 2016-04-27 HK HK18111487.7A patent/HK1252248A1/zh unknown
- 2016-04-27 US US15/570,075 patent/US10982258B2/en not_active Expired - Fee Related
- 2016-04-27 JP JP2017556123A patent/JP6894380B2/ja not_active Expired - Fee Related
-
2020
- 2020-08-31 US US17/008,535 patent/US20210079454A1/en not_active Abandoned
-
2021
- 2021-06-03 JP JP2021093583A patent/JP2021129601A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20190024145A1 (en) | 2019-01-24 |
| US10982258B2 (en) | 2021-04-20 |
| MX2017013471A (es) | 2018-08-01 |
| WO2016176322A1 (en) | 2016-11-03 |
| JP2018520639A (ja) | 2018-08-02 |
| AU2016253964A1 (en) | 2017-11-09 |
| EP3289082A1 (en) | 2018-03-07 |
| US20210079454A1 (en) | 2021-03-18 |
| CA2983937A1 (en) | 2016-11-03 |
| EP3289082A4 (en) | 2018-09-12 |
| CN107849560A (zh) | 2018-03-27 |
| AU2016253964B2 (en) | 2022-07-07 |
| JP2021129601A (ja) | 2021-09-09 |
| JP6894380B2 (ja) | 2021-06-30 |
| CN107849560B (zh) | 2021-10-22 |
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