HK1251166A1 - 平滑肌肉瘤的靶向療法 - Google Patents
平滑肌肉瘤的靶向療法Info
- Publication number
- HK1251166A1 HK1251166A1 HK18110654.6A HK18110654A HK1251166A1 HK 1251166 A1 HK1251166 A1 HK 1251166A1 HK 18110654 A HK18110654 A HK 18110654A HK 1251166 A1 HK1251166 A1 HK 1251166A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- leiomyosarcoma
- targeted treatment
- targeted
- treatment
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562147104P | 2015-04-14 | 2015-04-14 | |
PCT/US2016/026119 WO2016168014A1 (en) | 2015-04-14 | 2016-04-06 | Targeted treatment of leiomyosarcoma |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1251166A1 true HK1251166A1 (zh) | 2019-01-25 |
Family
ID=55752808
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK18110654.6A HK1251166A1 (zh) | 2015-04-14 | 2018-08-20 | 平滑肌肉瘤的靶向療法 |
Country Status (8)
Country | Link |
---|---|
US (1) | US10555951B2 (zh) |
EP (1) | EP3283079B1 (zh) |
JP (1) | JP6412278B2 (zh) |
CN (1) | CN107427523B (zh) |
ES (1) | ES2760462T3 (zh) |
HK (1) | HK1251166A1 (zh) |
TW (1) | TWI609687B (zh) |
WO (1) | WO2016168014A1 (zh) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI609687B (zh) | 2015-04-14 | 2018-01-01 | 美國禮來大藥廠 | 平滑肌肉瘤之標靶性治療 |
CN109071504B (zh) | 2016-02-05 | 2022-03-08 | 戴纳立制药公司 | 受体相互作用蛋白激酶1的抑制剂 |
ES2898952T3 (es) | 2016-04-12 | 2022-03-09 | Lilly Co Eli | Terapia de combinación con inhibidores de Notch y PI3K/mTOR para su uso en el tratamiento del cáncer de ovario |
KR102418765B1 (ko) | 2016-04-12 | 2022-07-08 | 일라이 릴리 앤드 캄파니 | 암 치료를 위한 Notch 및 CDK4/6 억제제의 조합 요법 |
SG11201810268YA (en) | 2016-05-20 | 2018-12-28 | Lilly Co Eli | Combination therapy with notch and pd-1 or pd-l1 inhibitors |
EP3506905B1 (en) * | 2016-08-31 | 2024-03-20 | Eli Lilly and Company | Dosage regimen for the treatment of solid tumors |
US11376259B2 (en) | 2016-10-12 | 2022-07-05 | Eli Lilly And Company | Targeted treatment of mature T-cell lymphoma |
CN110383066B (zh) | 2016-12-09 | 2023-03-31 | 戴纳立制药公司 | 化合物、组合物和方法 |
US11845803B2 (en) | 2017-02-17 | 2023-12-19 | Fred Hutchinson Cancer Center | Combination therapies for treatment of BCMA-related cancers and autoimmune disorders |
JP7233425B2 (ja) * | 2017-11-06 | 2023-03-06 | ジュノー セラピューティクス インコーポレイテッド | 細胞療法とガンマセクレターゼ阻害剤との組み合わせ |
AU2023206890A1 (en) | 2022-01-12 | 2024-08-22 | Denali Therapeutics Inc. | Crystalline forms of (s)-5-benzyl-n-(5-methyl-4-oxo-2, 3,4,5- tetrahydropyrido [3,2-b] [l,4]oxazepin-3-yl)-4h-l,2,4-triazole-3-carboxamide |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL196641B1 (pl) | 1996-12-23 | 2008-01-31 | Elan Pharm Inc | Związki laktamowe i środek farmaceutyczny |
JP2002526109A (ja) * | 1998-10-02 | 2002-08-20 | ザ ガバメント オブ ザ ユナイテッドステイツ オブ アメリカ アズ リプレゼンテッド バイ ザ セクレタリー デパートメント オブ ヘルス アンド ヒューマン サービシーズ ザ ナショナル インステ | アポトーシス誘導物質と方法 |
CN101583624B (zh) * | 2006-09-29 | 2012-11-21 | 昂考梅德药品有限公司 | 用于诊断和治疗癌症的组合物及其用途 |
JP5560270B2 (ja) * | 2008-07-08 | 2014-07-23 | オンコメッド ファーマシューティカルズ インコーポレイテッド | Notch結合剤およびアンタゴニストならびにその使用方法 |
JO2885B1 (en) | 2008-12-22 | 2015-03-15 | ايلي ليلي اند كومباني | Protein kinase inhibitors |
EP3029070A1 (en) * | 2009-08-29 | 2016-06-08 | AbbVie Inc. | Therapeutic dll4 binding proteins |
WO2011060051A1 (en) | 2009-11-12 | 2011-05-19 | University Of Massachusetts | Methods for treating glioblastoma |
JO3003B1 (ar) | 2011-01-14 | 2016-09-05 | Lilly Co Eli | مركب أيميدازو [4، 5 -c ] كينولين-2- واحد واستخدامه كمثبط كيناز PI3/mtor |
JO3148B1 (ar) * | 2011-07-27 | 2017-09-20 | Lilly Co Eli | مركب مثبط لإشارات مسار notch |
EP2897938B1 (en) * | 2012-09-21 | 2017-03-15 | Bristol-Myers Squibb Company | Fluoroalkyl dibenzodiazepinone compounds |
US10092645B2 (en) | 2014-06-17 | 2018-10-09 | Medimmune Limited | Methods of treatment with antagonists against PD-1 and PD-L1 in combination with radiation therapy |
US20180140602A1 (en) | 2015-04-07 | 2018-05-24 | Novartis Ag | Combination of chimeric antigen receptor therapy and amino pyrimidine derivatives |
TWI609687B (zh) | 2015-04-14 | 2018-01-01 | 美國禮來大藥廠 | 平滑肌肉瘤之標靶性治療 |
KR102418765B1 (ko) | 2016-04-12 | 2022-07-08 | 일라이 릴리 앤드 캄파니 | 암 치료를 위한 Notch 및 CDK4/6 억제제의 조합 요법 |
ES2898952T3 (es) | 2016-04-12 | 2022-03-09 | Lilly Co Eli | Terapia de combinación con inhibidores de Notch y PI3K/mTOR para su uso en el tratamiento del cáncer de ovario |
SG11201810268YA (en) | 2016-05-20 | 2018-12-28 | Lilly Co Eli | Combination therapy with notch and pd-1 or pd-l1 inhibitors |
EP3506905B1 (en) | 2016-08-31 | 2024-03-20 | Eli Lilly and Company | Dosage regimen for the treatment of solid tumors |
US11376259B2 (en) | 2016-10-12 | 2022-07-05 | Eli Lilly And Company | Targeted treatment of mature T-cell lymphoma |
EP3615055A1 (en) | 2017-04-28 | 2020-03-04 | Novartis AG | Cells expressing a bcma-targeting chimeric antigen receptor, and combination therapy with a gamma secretase inhibitor |
-
2016
- 2016-04-01 TW TW105110658A patent/TWI609687B/zh active
- 2016-04-06 US US15/560,676 patent/US10555951B2/en active Active
- 2016-04-06 ES ES16716435T patent/ES2760462T3/es active Active
- 2016-04-06 WO PCT/US2016/026119 patent/WO2016168014A1/en active Application Filing
- 2016-04-06 JP JP2017553909A patent/JP6412278B2/ja active Active
- 2016-04-06 EP EP16716435.9A patent/EP3283079B1/en active Active
- 2016-04-06 CN CN201680021715.2A patent/CN107427523B/zh active Active
-
2018
- 2018-08-20 HK HK18110654.6A patent/HK1251166A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
CN107427523A (zh) | 2017-12-01 |
US10555951B2 (en) | 2020-02-11 |
TW201709913A (zh) | 2017-03-16 |
ES2760462T3 (es) | 2020-05-14 |
EP3283079A1 (en) | 2018-02-21 |
JP6412278B2 (ja) | 2018-10-24 |
EP3283079B1 (en) | 2019-09-25 |
US20180104254A1 (en) | 2018-04-19 |
TWI609687B (zh) | 2018-01-01 |
WO2016168014A1 (en) | 2016-10-20 |
JP2018511629A (ja) | 2018-04-26 |
CN107427523B (zh) | 2020-08-14 |
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