HK1250982A1 - 羧酸取代的(雜)芳環類衍生物及其製備方法和用途 - Google Patents
羧酸取代的(雜)芳環類衍生物及其製備方法和用途Info
- Publication number
- HK1250982A1 HK1250982A1 HK18110357.6A HK18110357A HK1250982A1 HK 1250982 A1 HK1250982 A1 HK 1250982A1 HK 18110357 A HK18110357 A HK 18110357A HK 1250982 A1 HK1250982 A1 HK 1250982A1
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- Prior art keywords
- hetero
- preparation
- aromatic ring
- ring derivatives
- carboxy substituted
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- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
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CN110612286A (zh) * | 2017-02-28 | 2019-12-24 | 广东东阳光药业有限公司 | 氰基取代的稠合双环衍生物及其制备方法和用途 |
ES2639863B1 (es) * | 2017-03-10 | 2018-09-20 | Universidad De Granada | Compuestos para el tratamiento de enfermedades causadas por la acumulación de oxalato |
WO2019057946A1 (en) | 2017-09-25 | 2019-03-28 | F. Hoffmann-La Roche Ag | MULTI-CYCLIC AROMATIC COMPOUNDS AS D-FACTOR INHIBITORS |
CN109503513B (zh) * | 2018-12-29 | 2020-09-25 | 嘉实(湖南)医药科技有限公司 | 一种非布司他中间体的“一锅法”合成方法 |
CN111943957B (zh) * | 2019-05-17 | 2023-01-06 | 中国医学科学院药物研究所 | 喹啉甲酰胺类化合物及其制备方法和用途 |
EP4053114B1 (en) * | 2019-10-30 | 2024-10-09 | Dongbao Purple Star (Hangzhou) Biopharmaceutical Co., Ltd. | Thiophene derivatives as xanthine oxidase inhibitors and application thereof |
WO2021204884A1 (de) * | 2020-04-09 | 2021-10-14 | Bayer Aktiengesellschaft | 3-(4-alkenyl-phenyl)-3-pyrrolin-2-one und deren verwendung als herbizide |
CN113105481A (zh) * | 2021-02-25 | 2021-07-13 | 浙江农林大学暨阳学院 | 一种双金属催化制备苯并-6,8-二氢异喹啉-1-亚硒砜基苯甲酰胺类化合物的方法 |
KR20240004711A (ko) * | 2021-04-29 | 2024-01-11 | 둥바오 퍼플 스타 (항저우) 바이오파마슈티컬 컴퍼니 리미티드 | 티오펜 유도체의 결정형 및 이의 제조 방법 |
WO2023208103A1 (zh) * | 2022-04-27 | 2023-11-02 | 江苏新元素医药科技有限公司 | 可用于痛风的化合物 |
CN115417804A (zh) * | 2022-09-16 | 2022-12-02 | 天津药明康德新药开发有限公司 | 一种7-甲基-1h-吲哚-5-羧酸的合成方法 |
CN116375603A (zh) * | 2023-03-03 | 2023-07-04 | 大连理工大学 | 一种合成苯丙环丁烯衍生物的方法 |
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AU642743B2 (en) | 1990-05-21 | 1993-10-28 | Smith Kline & French Laboratories Limited | Phenol and pyridinol derivatives as pharmaceuticals |
ATE142494T1 (de) * | 1990-11-30 | 1996-09-15 | Teijin Ltd | 2-arylthiazolderivat sowie dieses enthaltendes arzneimittel |
PT2133332E (pt) | 2007-04-11 | 2013-10-03 | Kissei Pharmaceutical | Derivado de (aza)indole e sua utilização para fins médicos |
WO2010044405A1 (ja) | 2008-10-15 | 2010-04-22 | キッセイ薬品工業株式会社 | 縮合環誘導体及びその医薬用途 |
US20110201815A1 (en) * | 2008-10-15 | 2011-08-18 | Kissei Pharmaceutical Co., Ltd. | Fused heterocyclic derivative and use thereof for medical purposes |
KR20100092909A (ko) * | 2009-02-13 | 2010-08-23 | 주식회사 엘지생명과학 | 잔틴 옥시다제 저해제로서 효과적인 신규 화합물, 그 제조방법 및 그를 함유하는 약제학적 조성물 |
RU2529868C2 (ru) | 2009-03-31 | 2014-10-10 | Кисcеи Фармасьютикал Ко., Лтд. | Производное индолизина и его применение в медицинских целях |
TWI423962B (zh) * | 2009-10-07 | 2014-01-21 | Lg Life Sciences Ltd | 有效作為黃嘌呤氧化酶抑制劑之新穎化合物、其製備方法及含該化合物之醫藥組成物 |
CN103221412B (zh) | 2010-09-29 | 2015-08-19 | 橘生药品工业株式会社 | (氮杂)中氮茚衍生物及其药物用途 |
JP6377732B2 (ja) | 2013-06-21 | 2018-08-22 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングMerck Patent Gesellschaft mit beschraenkter Haftung | 1,3−ジアミノシクロペンタンカルボキサミド誘導体 |
JP2015214527A (ja) * | 2014-05-13 | 2015-12-03 | 帝人ファーマ株式会社 | イミダゾール誘導体 |
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US20180230102A1 (en) | 2018-08-16 |
EP3344604A4 (en) | 2019-02-06 |
TW201710236A (zh) | 2017-03-16 |
DK3344604T3 (da) | 2020-12-07 |
KR102635986B1 (ko) | 2024-02-08 |
CA2994336C (en) | 2024-03-05 |
KR20180041747A (ko) | 2018-04-24 |
CA2994336A1 (en) | 2017-03-09 |
AU2016316278A1 (en) | 2018-03-01 |
WO2017036404A1 (en) | 2017-03-09 |
TWI733692B (zh) | 2021-07-21 |
JP2018532698A (ja) | 2018-11-08 |
EP3344604B1 (en) | 2020-11-04 |
EP3344604A1 (en) | 2018-07-11 |
HUE052608T2 (hu) | 2021-05-28 |
ES2839201T3 (es) | 2021-07-05 |
CN106478500B (zh) | 2020-02-11 |
JP6859323B2 (ja) | 2021-04-14 |
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