HK1248540A1 - 用於靶向药物递送的自组装分子 - Google Patents

用於靶向药物递送的自组装分子 Download PDF

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Publication number
HK1248540A1
HK1248540A1 HK18108192.9A HK18108192A HK1248540A1 HK 1248540 A1 HK1248540 A1 HK 1248540A1 HK 18108192 A HK18108192 A HK 18108192A HK 1248540 A1 HK1248540 A1 HK 1248540A1
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HK
Hong Kong
Prior art keywords
drug delivery
targeted drug
self assembling
assembling molecules
self
Prior art date
Application number
HK18108192.9A
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English (en)
Chinese (zh)
Inventor
David R. Elmaleh
Kazue Takahashi
Original Assignee
The General Hospital Corporation
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Publication date
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Publication of HK1248540A1 publication Critical patent/HK1248540A1/zh

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5169—Proteins, e.g. albumin, gelatin
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    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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    • A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
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    • A61K47/6921—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere
    • A61K47/6925—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being a microcapsule, nanocapsule, microbubble or nanobubble
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    • A61K49/1818—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles
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  • Animal Behavior & Ethology (AREA)
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  • General Health & Medical Sciences (AREA)
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  • Pharmacology & Pharmacy (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Nanotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Optics & Photonics (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • Dispersion Chemistry (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
HK18108192.9A 2015-03-31 2016-03-31 用於靶向药物递送的自组装分子 HK1248540A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562140696P 2015-03-31 2015-03-31
US62/140,696 2015-03-31
PCT/US2016/025290 WO2016161129A1 (en) 2015-03-31 2016-03-31 Self assembling molecules for targeted drug delivery

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Publication Number Publication Date
HK1248540A1 true HK1248540A1 (zh) 2018-10-19

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US (2) US20180140719A1 (cg-RX-API-DMAC10.html)
EP (2) EP3936121A1 (cg-RX-API-DMAC10.html)
JP (2) JP2018513142A (cg-RX-API-DMAC10.html)
CN (1) CN107613963A (cg-RX-API-DMAC10.html)
AU (1) AU2016242920B2 (cg-RX-API-DMAC10.html)
CA (1) CA2980329C (cg-RX-API-DMAC10.html)
HK (1) HK1248540A1 (cg-RX-API-DMAC10.html)
MA (1) MA41866A (cg-RX-API-DMAC10.html)
MX (2) MX394468B (cg-RX-API-DMAC10.html)
WO (1) WO2016161129A1 (cg-RX-API-DMAC10.html)

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MA41866A (fr) 2018-02-06
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MX394468B (es) 2025-03-21
CN107613963A (zh) 2018-01-19
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MX2022009027A (es) 2022-08-11
US20180140719A1 (en) 2018-05-24
AU2016242920B2 (en) 2021-10-21
CA2980329A1 (en) 2016-10-06
EP3277268A1 (en) 2018-02-07
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